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Performance of 99mTc-aprotinin scintigraphy for diagnosing light chain (AL) cardiac amyloidosis confirmed by endomyocardial biopsy.

Awaya T, Minamimoto R, Iwama K, Kubota S, Hotta M, Hirai R, Yamamoto M, Okazaki O, Hara H, Hiroi Y, Hiroe M, Moroi M.

J Nucl Cardiol. 2019 Oct 7. doi: 10.1007/s12350-019-01868-9. [Epub ahead of print]


Diagnostic value of lead aVR in electrocardiography for identifying acute coronary lesions in patients with out-of-hospital cardiac arrest.

Yamamoto M, Witsch T, Kubota S, Hara H, Hiroi Y.

Resuscitation. 2019 Sep;142:97-103. doi: 10.1016/j.resuscitation.2019.07.017. Epub 2019 Jul 19.


Transmitral inflow wave and progression from paroxysmal to permanent atrial fibrillation in Asian people.

Nakagawa T, Hara H, Yamamoto M, Matsushita Y, Hiroi Y.

Heart Asia. 2019 Jun 26;11(2):e011166. doi: 10.1136/heartasia-2018-011166. eCollection 2019.


A case of prominent coronary plaque regression with statin therapy.

Awaya T, Kodama C, Yamamoto M, Okazaki O, Hara H, Hiroi Y, Moroi M.

J Cardiovasc Comput Tomogr. 2019 May 3. pii: S1934-5925(19)30004-8. doi: 10.1016/j.jcct.2019.05.002. [Epub ahead of print] No abstract available.


The predictors of complications in balloon pulmonary angioplasty for chronic thromboembolic pulmonary hypertension.

Ikeda N, Kubota S, Okazaki T, Iijima R, Hara H, Hiroi Y, Nakamura M.

Catheter Cardiovasc Interv. 2019 May 1;93(6):E349-E356. doi: 10.1002/ccd.28133. Epub 2019 Feb 17.


Pacemaker malfunction after acute myocardial infarction in a patient with wrap-around left anterior descending artery supplying the right ventricular apex.

Umei TC, Awaya T, Okazaki O, Hara H, Hiroi Y.

J Cardiol Cases. 2018 Apr 4;18(1):9-12. doi: 10.1016/j.jccase.2018.03.001. eCollection 2018 Jul.


Significance of 11C-PIB PET/CT in cardiac amyloidosis compared with 99mTc-aprotinin scintigraphy: A pilot study.

Minamimoto R, Awaya T, Iwama K, Hotta M, Nakajima K, Hirai R, Okazaki O, Hiroi Y.

J Nucl Cardiol. 2018 Mar 27. doi: 10.1007/s12350-018-1260-5. [Epub ahead of print]


HySAR: Hybrid Material Rendering by an Optical See-Through Head-Mounted Display with Spatial Augmented Reality Projection.

Hamasaki T, Itoh Y, Hiroi Y, Iwai D, Sugimoto M.

IEEE Trans Vis Comput Graph. 2018 Apr;24(4):1457-1466. doi: 10.1109/TVCG.2018.2793659.


11C-4DST PET/CT Imaging of Cardiac Sarcoidosis: Comparison With 18F-FDG and Cardiac MRI.

Hotta M, Minamimoto R, Kubota S, Awaya T, Hiroi Y.

Clin Nucl Med. 2018 Jun;43(6):458-459. doi: 10.1097/RLU.0000000000002059.


Effect of Oral Branched-Chain Amino Acids on Serum Albumin Concentration in Heart Failure Patients with Hypoalbuminemia: Results of a Preliminary Study.

Uchino Y, Watanabe M, Takata M, Amiya E, Tsushima K, Adachi T, Hiroi Y, Funazaki T, Komuro I.

Am J Cardiovasc Drugs. 2018 Aug;18(4):327-332. doi: 10.1007/s40256-018-0269-0.


Neuroprotection Mediated by Upregulation of Endothelial Nitric Oxide Synthase in Rho-Associated, Coiled-Coil-Containing Kinase 2 Deficient Mice.

Hiroi Y, Noma K, Kim HH, Sladojevic N, Tabit CE, Li Y, Soydan G, Salomone S, Moskowitz MA, Liao JK.

Circ J. 2018 Mar 23;82(4):1195-1204. doi: 10.1253/circj.CJ-17-0732. Epub 2018 Jan 19.


Walking through Apertures in Individuals with Stroke.

Muroi D, Hiroi Y, Koshiba T, Suzuki Y, Kawaki M, Higuchi T.

PLoS One. 2017 Jan 19;12(1):e0170119. doi: 10.1371/journal.pone.0170119. eCollection 2017.


Sustained effects of once-a-week gait training with hybrid assistive limb for rehabilitation in chronic stroke: case study.

Yoshimoto T, Shimizu I, Hiroi Y.

J Phys Ther Sci. 2016 Sep;28(9):2684-2687. Epub 2016 Sep 29.


Impact of serum 1,5-anhydro-d-glucitol level on prediction of major adverse cardiac and cerebrovascular events in non-diabetic patients without coronary artery disease.

Ikeda N, Hara H, Hiroi Y, Nakamura M.

Atherosclerosis. 2016 Oct;253:1-6. doi: 10.1016/j.atherosclerosis.2016.08.016. Epub 2016 Aug 20.


Computed tomography imaging to quantify the area of the endocardial subvalvular apparatus in hypertrophic cardiomyopathy - Relationship to outflow tract obstruction and symptoms.

Tajima M, Iguchi N, Utanohara Y, Hiroi Y, Mahara K, Niwa T, Takayama M, Sumiyoshi T, Tomoike H.

J Cardiovasc Comput Tomogr. 2016 Sep-Oct;10(5):351-8. doi: 10.1016/j.jcct.2016.07.015. Epub 2016 Jul 19.


Biotin augments acetyl CoA carboxylase 2 gene expression in the hypothalamus, leading to the suppression of food intake in mice.

Sone H, Kamiyama S, Higuchi M, Fujino K, Kubo S, Miyazawa M, Shirato S, Hiroi Y, Shiozawa K.

Biochem Biophys Res Commun. 2016 Jul 29;476(3):134-9. doi: 10.1016/j.bbrc.2016.04.152. Epub 2016 May 12.


Comparison of intravascular optical frequency domain imaging versus intravascular ultrasound during balloon pulmonary angioplasty in patients with chronic thromboembolic pulmonary hypertension.

Ikeda N, Kubota S, Okazaki T, Hara H, Hiroi Y.

Catheter Cardiovasc Interv. 2016 Jun;87(7):E268-74. doi: 10.1002/ccd.26437. Epub 2016 Mar 18.


Ability of 1,5-Anhydro-d-glucitol Values to Predict Coronary Artery Disease in a Non-Diabetic Population.

Ikeda N, Hara H, Hiroi Y.

Int Heart J. 2015;56(6):587-91. doi: 10.1536/ihj.15-177. Epub 2015 Nov 6.


Feasibility and efficacy of high-speed gait training with a voluntary driven exoskeleton robot for gait and balance dysfunction in patients with chronic stroke: nonrandomized pilot study with concurrent control.

Yoshimoto T, Shimizu I, Hiroi Y, Kawaki M, Sato D, Nagasawa M.

Int J Rehabil Res. 2015 Dec;38(4):338-43. doi: 10.1097/MRR.0000000000000132.


Patterning of photocleavable zwitterionic polymer brush fabricated on silicon wafer.

Kamada T, Yamazawa Y, Nakaji-Hirabayashi T, Kitano H, Usui Y, Hiroi Y, Kishioka T.

Colloids Surf B Biointerfaces. 2014 Nov 1;123:878-86. doi: 10.1016/j.colsurfb.2014.10.039. Epub 2014 Oct 30.


IgG4-related cardiovascular disorders.

Tajima M, Nagai R, Hiroi Y.

Int Heart J. 2014;55(4):287-95. Epub 2014 Jun 5. Review.


1,5-Anhydro-D-glucitol predicts coronary artery disease prevalence and complexity.

Ikeda N, Hara H, Hiroi Y.

J Cardiol. 2014 Oct;64(4):297-301. doi: 10.1016/j.jjcc.2014.02.014. Epub 2014 Mar 26.


Immunoglobulin G4-related multiple systemic aneurysms and splenic aneurysm rupture during steroid therapy.

Tajima M, Hiroi Y, Takazawa Y, Muraoka H, Iwata H, Yamashita H, Hirata Y, Nagai R.

Hum Pathol. 2014 Jan;45(1):175-9. doi: 10.1016/j.humpath.2013.07.035. Epub 2013 Oct 15.


Asymmetric cross-dimerization between methyl methacrylate and substituted alkene by Ru(0)-bicyclononadiene complex.

Hiroi Y, Komine N, Komiya S, Hirano M.

Org Lett. 2013 May 17;15(10):2486-9. doi: 10.1021/ol400963d. Epub 2013 May 9.


FHL2 prevents cardiac hypertrophy in mice with cardiac-specific deletion of ROCK2.

Okamoto R, Li Y, Noma K, Hiroi Y, Liu PY, Taniguchi M, Ito M, Liao JK.

FASEB J. 2013 Apr;27(4):1439-49. doi: 10.1096/fj.12-217018. Epub 2012 Dec 27.


Notch1 in bone marrow-derived cells mediates cardiac repair after myocardial infarction.

Li Y, Hiroi Y, Ngoy S, Okamoto R, Noma K, Wang CY, Wang HW, Zhou Q, Radtke F, Liao R, Liao JK.

Circulation. 2011 Mar 1;123(8):866-76. doi: 10.1161/CIRCULATIONAHA.110.947531. Epub 2011 Feb 14.


Notch signaling as an important mediator of cardiac repair and regeneration after myocardial infarction.

Li Y, Hiroi Y, Liao JK.

Trends Cardiovasc Med. 2010 Oct;20(7):228-31. doi: 10.1016/j.tcm.2011.11.006. Review.


The thread and streaks sign.

Matsumoto N, Ogawa M, Abe M, Nakagawara H, Hiroi Y, Yamamoto T, Moriyama M.

J Med Ultrason (2001). 2009 Jun;36(2):99-100. doi: 10.1007/s10396-008-0207-x. Epub 2009 Jun 17. No abstract available.


Obesity increases vascular senescence and susceptibility to ischemic injury through chronic activation of Akt and mTOR.

Wang CY, Kim HH, Hiroi Y, Sawada N, Salomone S, Benjamin LE, Walsh K, Moskowitz MA, Liao JK.

Sci Signal. 2009 Mar 17;2(62):ra11. doi: 10.1126/scisignal.2000143.


[Visions of aged society and the reorganizations of social security and community].

Hiroi Y.

Nihon Ronen Igakkai Zasshi. 2008 Sep;45(5):474-6. Japanese. No abstract available.


A crucial role of a high mobility group protein HMGA2 in cardiogenesis.

Monzen K, Ito Y, Naito AT, Kasai H, Hiroi Y, Hayashi D, Shiojima I, Yamazaki T, Miyazono K, Asashima M, Nagai R, Komuro I.

Nat Cell Biol. 2008 May;10(5):567-74. doi: 10.1038/ncb1719. Epub 2008 Apr 20.


ROCK1 mediates leukocyte recruitment and neointima formation following vascular injury.

Noma K, Rikitake Y, Oyama N, Yan G, Alcaide P, Liu PY, Wang H, Ahl D, Sawada N, Okamoto R, Hiroi Y, Shimizu K, Luscinskas FW, Sun J, Liao JK.

J Clin Invest. 2008 May;118(5):1632-44. doi: 10.1172/JCI29226.


Dynamic regulation of endothelial NOS mediated by competitive interaction with alpha-actinin-4 and calmodulin.

Hiroi Y, Guo Z, Li Y, Beggs AH, Liao JK.

FASEB J. 2008 May;22(5):1450-7. doi: 10.1096/fj.07-9309com. Epub 2008 Jan 7.


Clinical efficacy of contrast-enhanced ultrasonography (CEUS) in the diagnosis of ruptured hepatocellular carcinoma (HCC).

Matsumoto N, Ogawa M, Nakagawara H, Hiroi Y, Yamamoto T, Arakawa Y, Ishida H, Komatsuda T, Yamada M, Yagisawa H.

J Med Ultrason (2001). 2007 Jun;34(2):101-5. doi: 10.1007/s10396-007-0136-0. Epub 2007 Jun 21.


Evaluation of malignancy of hepatocellular carcinoma using the ultrasonic B-mode method: clinical significance of extracapsular invasion of hepatocellular carcinoma using ultrasonography.

Nakagawara H, Ogawa M, Matsumoto N, Hiroi Y, Yamamoto T, Ono Y, Arakawa Y, Takayama T, Kinukawa N, Ishida H.

J Med Ultrason (2001). 2007 Jun;34(2):83-91. doi: 10.1007/s10396-007-0142-2. Epub 2007 Jun 21.


Pseudolymphoma of the liver: Sonographic findings and review of the literature.

Matsumoto N, Ogawa M, Kawabata M, Tohne R, Hiroi Y, Furuta T, Yamamoto T, Gotoh I, Ishiwata H, Ono Y, Arakawa Y, Kinukawa N.

J Clin Ultrasound. 2007 Jun;35(5):284-8. Review.


Expression of MAK-V/Hunk in renal distal tubules and its possible involvement in proliferative suppression.

Sakai M, Tamura K, Tsurumi Y, Tanaka Y, Koide Y, Matsuda M, Ishigami T, Yabana M, Tokita Y, Hiroi Y, Komuro I, Umemura S.

Am J Physiol Renal Physiol. 2007 May;292(5):F1526-36. Epub 2007 Feb 13.


Rapid nongenomic actions of thyroid hormone.

Hiroi Y, Kim HH, Ying H, Furuya F, Huang Z, Simoncini T, Noma K, Ueki K, Nguyen NH, Scanlan TS, Moskowitz MA, Cheng SY, Liao JK.

Proc Natl Acad Sci U S A. 2006 Sep 19;103(38):14104-9. Epub 2006 Sep 11.


Cathepsin L plays an important role in the lysosomal degradation of L-lactate dehydrogenase.

Ohshita T, Hiroi Y.

Biosci Biotechnol Biochem. 2006 Sep;70(9):2254-61. Epub 2006 Sep 7.


Decreased vascular lesion formation in mice with inducible endothelial-specific expression of protein kinase Akt.

Mukai Y, Rikitake Y, Shiojima I, Wolfrum S, Satoh M, Takeshita K, Hiroi Y, Salomone S, Kim HH, Benjamin LE, Walsh K, Liao JK.

J Clin Invest. 2006 Feb;116(2):334-43.


Carvedilol therapy improved left ventricular function in a patient with arrhythmogenic right ventricular cardiomyopathy.

Hiroi Y, Fujiu K, Komatsu S, Sonoda M, Sakomura Y, Imai Y, Oishi Y, Nakamura F, Ajiki K, Hayami N, Murakawa Y, Ohno M, Hirata Y, Ohtomo K, Nagai R.

Jpn Heart J. 2004 Jan;45(1):169-77.


Novel TBX5 mutations and molecular mechanism for Holt-Oram syndrome.

Fan C, Duhagon MA, Oberti C, Chen S, Hiroi Y, Komuro I, Duhagon PI, Canessa R, Wang Q.

J Med Genet. 2003 Mar;40(3):e29. No abstract available.


Exacerbation of Lambert-Eaton myasthenic syndrome caused by an L-type Ca2+ channel antagonist.

Hiroi Y, Nakao T, Tsuchiya N, Takeda N, Maemura K, Nakamura F, Ohno M, Hirata Y, Nagai R.

Jpn Heart J. 2003 Jan;44(1):139-44.


Proprotein interaction with the GPI transamidase.

Chen R, Anderson V, Hiroi Y, Medof ME.

J Cell Biochem. 2003 Apr 1;88(5):1025-37.


Unimolecular metastable decompositions of 1,1,1-trifluoroisopropyl methyl ether [CF3(CH3)CHOCH3] upon electron ionization.

Tajima S, Kojima S, Hiroi Y, Mamada M, Nakajima S, Nibbering NM.

Rapid Commun Mass Spectrom. 2003;17(5):503-6. No abstract available.


Dual effects of the homeobox transcription factor Csx/Nkx2-5 on cardiomyocytes.

Monzen K, Zhu W, Kasai H, Hiroi Y, Hosoda T, Akazawa H, Zou Y, Hayashi D, Yamazaki T, Nagai R, Komuro I.

Biochem Biophys Res Commun. 2002 Nov 8;298(4):493-500.


Novel point mutation in the cardiac transcription factor CSX/NKX2.5 associated with congenital heart disease.

Ikeda Y, Hiroi Y, Hosoda T, Utsunomiya T, Matsuo S, Ito T, Inoue J, Sumiyoshi T, Takano H, Nagai R, Komuro I.

Circ J. 2002 Jun;66(6):561-3.


Csx/Nkx2-5 is required for homeostasis and survival of cardiac myocytes in the adult heart.

Toko H, Zhu W, Takimoto E, Shiojima I, Hiroi Y, Zou Y, Oka T, Akazawa H, Mizukami M, Sakamoto M, Terasaki F, Kitaura Y, Takano H, Nagai T, Nagai R, Komuro I.

J Biol Chem. 2002 Jul 5;277(27):24735-43. Epub 2002 Mar 11.


[An investigation of the use of diskhaleres in asthmatic patients].

Hiroi Y, Kuwabara A, Yoshimine F.

Arerugi. 2002 Jan;51(1):30-2. Japanese. No abstract available.


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