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Items: 1 to 50 of 239

1.

Development of Rice-Seed-Based Oral Allergy Vaccines Containing Hypoallergenic Japanese Cedar Pollen Allergen Derivatives for Immunotherapy.

Takaiwa F, Yang L, Takagi H, Maruyama N, Wakasa Y, Ozawa K, Hiroi T.

J Agric Food Chem. 2019 Nov 14. doi: 10.1021/acs.jafc.9b05421. [Epub ahead of print]

PMID:
31682438
2.

Basophil-expressing genes related with the efficacy of sublingual immunotherapy.

Gotoh M, Kaminuma O, Nakaya A, Saeki M, Nishimura T, Kitamura N, Hiroi T, Kimihiro Okubo A.

J Nippon Med Sch. 2019 Sep 30. doi: 10.1272/jnms.JNMS.2020_87-104. [Epub ahead of print]

3.

LAT1-specific inhibitor is effective against T cell-mediated allergic skin inflammation.

Hayashi K, Kaminuma O, Nishimura T, Saeki M, Matsuoka K, Hiroi T, Jutabha P, Iwata Y, Sugiura K, Owada T, Kurasawa K, Okayasu I, Ouchi M, Fujita T, Kanai Y, Endou H, Anzai N.

Allergy. 2019 Aug 12. doi: 10.1111/all.14019. [Epub ahead of print] No abstract available.

PMID:
31403710
4.

AL amyloidosis diagnosed using anti-IGLL5 antibody: a case report.

Hiroi T, Mushino T, Tanaka K, Furuya Y, Hori Y, Oiwa T, Kobata H, Yamashita Y, Hosoi H, Murata S, Nishikawa A, Tamura S, Takeuchi S, Nohgawa M, Yamashita T, Ando Y, Hata H, Sonoki T.

Amyloid. 2019;26(sup1):111-112. doi: 10.1080/13506129.2019.1585343. No abstract available.

PMID:
31343322
5.

[Mechanisms of allergen immunotherapy elucidated through integrated comparative analysis].

Kaminuma O, Gotoh M, Okubo K, Nakaya A, Hiroi T.

Nihon Yakurigaku Zasshi. 2019;154(1):23-27. doi: 10.1254/fpj.154.23. Review. Japanese.

PMID:
31308346
6.

Potential Mechanisms of T Cell-Mediated and Eosinophil-Independent Bronchial Hyperresponsiveness.

Saeki M, Nishimura T, Kitamura N, Hiroi T, Mori A, Kaminuma O.

Int J Mol Sci. 2019 Jun 18;20(12). pii: E2980. doi: 10.3390/ijms20122980. Review.

7.

Thrombospondin 1-mediated suppression of mast cell degranulation is involved in the efficacy of sublingual immunotherapy.

Kaminuma O, Kitamura N, Gotoh M, Shindo M, Watanabe N, Saeki M, Nishimura T, Mori A, Nemoto S, Tatsumi H, Okubo K, Hiroi T.

Allergol Int. 2019 Sep;68S:S9-S10. doi: 10.1016/j.alit.2019.03.007. Epub 2019 Apr 25. No abstract available.

8.

The surface composition of asteroid 162173 Ryugu from Hayabusa2 near-infrared spectroscopy.

Kitazato K, Milliken RE, Iwata T, Abe M, Ohtake M, Matsuura S, Arai T, Nakauchi Y, Nakamura T, Matsuoka M, Senshu H, Hirata N, Hiroi T, Pilorget C, Brunetto R, Poulet F, Riu L, Bibring JP, Takir D, Domingue DL, Vilas F, Barucci MA, Perna D, Palomba E, Galiano A, Tsumura K, Osawa T, Komatsu M, Nakato A, Arai T, Takato N, Matsunaga T, Takagi Y, Matsumoto K, Kouyama T, Yokota Y, Tatsumi E, Sakatani N, Yamamoto Y, Okada T, Sugita S, Honda R, Morota T, Kameda S, Sawada H, Honda C, Yamada M, Suzuki H, Yoshioka K, Hayakawa M, Ogawa K, Cho Y, Shirai K, Shimaki Y, Hirata N, Yamaguchi A, Ogawa N, Terui F, Yamaguchi T, Takei Y, Saiki T, Nakazawa S, Tanaka S, Yoshikawa M, Watanabe S, Tsuda Y.

Science. 2019 Apr 19;364(6437):272-275. doi: 10.1126/science.aav7432. Epub 2019 Mar 19.

PMID:
30890589
9.

The geomorphology, color, and thermal properties of Ryugu: Implications for parent-body processes.

Sugita S, Honda R, Morota T, Kameda S, Sawada H, Tatsumi E, Yamada M, Honda C, Yokota Y, Kouyama T, Sakatani N, Ogawa K, Suzuki H, Okada T, Namiki N, Tanaka S, Iijima Y, Yoshioka K, Hayakawa M, Cho Y, Matsuoka M, Hirata N, Hirata N, Miyamoto H, Domingue D, Hirabayashi M, Nakamura T, Hiroi T, Michikami T, Michel P, Ballouz RL, Barnouin OS, Ernst CM, Schröder SE, Kikuchi H, Hemmi R, Komatsu G, Fukuhara T, Taguchi M, Arai T, Senshu H, Demura H, Ogawa Y, Shimaki Y, Sekiguchi T, Müller TG, Hagermann A, Mizuno T, Noda H, Matsumoto K, Yamada R, Ishihara Y, Ikeda H, Araki H, Yamamoto K, Abe S, Yoshida F, Higuchi A, Sasaki S, Oshigami S, Tsuruta S, Asari K, Tazawa S, Shizugami M, Kimura J, Otsubo T, Yabuta H, Hasegawa S, Ishiguro M, Tachibana S, Palmer E, Gaskell R, Le Corre L, Jaumann R, Otto K, Schmitz N, Abell PA, Barucci MA, Zolensky ME, Vilas F, Thuillet F, Sugimoto C, Takaki N, Suzuki Y, Kamiyoshihara H, Okada M, Nagata K, Fujimoto M, Yoshikawa M, Yamamoto Y, Shirai K, Noguchi R, Ogawa N, Terui F, Kikuchi S, Yamaguchi T, Oki Y, Takao Y, Takeuchi H, Ono G, Mimasu Y, Yoshikawa K, Takahashi T, Takei Y, Fujii A, Hirose C, Nakazawa S, Hosoda S, Mori O, Shimada T, Soldini S, Iwata T, Abe M, Yano H, Tsukizaki R, Ozaki M, Nishiyama K, Saiki T, Watanabe S, Tsuda Y.

Science. 2019 Apr 19;364(6437):252. doi: 10.1126/science.aaw0422. Epub 2019 Mar 19.

PMID:
30890587
10.

[Refractory ascites developing in late-phase of cord blood transplantation improving with CART].

Hiroi T, Mushino T, Tanaka K, Yamashita Y, Kuriyama K, Murata S, Furuya Y, Hori Y, Oiwa T, Kobata H, Hosoi H, Nishikawa A, Tamura S, Sonoki T.

Rinsho Ketsueki. 2019;60(2):130-133. doi: 10.11406/rinketsu.60.130. Japanese.

PMID:
30842380
11.

Serum Cytokine Interactions Are Implicated in the Mechanism of Action of Sublingual Immunotherapy for Japanese Cedar Pollinosis.

Shimada K, Gotoh M, Okubo K, Hiroi T, Kaminuma O, Nakaya A.

J Nippon Med Sch. 2018;85(5):250-258. doi: 10.1272/jnms.JNMS.2018_85-40.

12.

Microarray-Based Multivariate Analysis of the Effectiveness of Sublingual Immunotherapy for Cedar Pollinosis.

Gotoh M, Kaminuma O, Hiroi T, Okubo K.

Allergy Asthma Immunol Res. 2018 Sep;10(5):562-569. doi: 10.4168/aair.2018.10.5.562.

13.

Effects of anti-allergic drugs on T cell-mediated nasal hyperresponsiveness in a murine model of allergic rhinitis.

Nishimura T, Kaminuma O, Saeki M, Kitamura N, Gotoh M, Mori A, Hiroi T.

Allergol Int. 2018 Sep;67S:S25-S31. doi: 10.1016/j.alit.2018.05.002. Epub 2018 Jun 15.

14.

Involvement of taste receptors in the effectiveness of sublingual immunotherapy.

Gotoh M, Kaminuma O, Nakaya A, Katayama K, Watanabe N, Saeki M, Nishimura T, Kitamura N, Okubo K, Hiroi T.

Allergol Int. 2018 Jul;67(3):421-424. doi: 10.1016/j.alit.2018.02.003. Epub 2018 Mar 6. No abstract available.

15.

Contribution of neuraminidase 3 to the differentiation of induced regulatory T cells.

Kaminuma O, Katoh S, Miyagi T, Watanabe N, Kitamura N, Nishimura T, Saeki M, Mori A, Hiroi T.

Genes Cells. 2018 Feb;23(2):112-116. doi: 10.1111/gtc.12553. Epub 2017 Dec 22.

16.

Downregulation of NFAT3 Due to Lack of T-Box Transcription Factor TBX5 Is Crucial for Cytokine Expression in T Cells.

Kaminuma O, Kitamura N, Nishito Y, Nemoto S, Tatsumi H, Mori A, Hiroi T.

J Immunol. 2018 Jan 1;200(1):92-100. doi: 10.4049/jimmunol.1602113. Epub 2017 Nov 27.

17.

T-Helper Type 2 Cells Direct Antigen-Induced Eosinophilic Skin Inflammation in Mice.

Kaminuma O, Nishimura T, Kitamura N, Saeki M, Hiroi T, Mori A.

Allergy Asthma Immunol Res. 2018 Jan;10(1):77-82. doi: 10.4168/aair.2018.10.1.77.

18.

Differential Contribution of Adhesion Molecules to Th1 and Th2 Cell-Mediated Lung and Bowel Inflammation.

Kaminuma O, Saeki M, Nishimura T, Kitamura N, Watanabe N, Hiroi T, Mori A.

Biol Pharm Bull. 2017;40(10):1801-1805. doi: 10.1248/bpb.b17-00279.

19.

Oral administration of ovalbumin after sensitization attenuates symptoms in a mouse model of food allergic enteropathy.

Hiraide E, Morinaga M, Hidaka H, Yamada S, Takeyama J, Kitamura N, Kaminuma O, Hiroi T, Du W, Ohashi-Doi K, Nakajima-Adachi H, Hachimura S.

Biosci Biotechnol Biochem. 2017 Oct;81(10):1967-1972. doi: 10.1080/09168451.2017.1361806. Epub 2017 Aug 16.

PMID:
28812470
20.

Th9 cells induce steroid-resistant bronchial hyperresponsiveness in mice.

Saeki M, Kaminuma O, Nishimura T, Kitamura N, Mori A, Hiroi T.

Allergol Int. 2017 Sep;66S:S35-S40. doi: 10.1016/j.alit.2017.07.001. Epub 2017 Jul 26.

21.

Identification of biomarker sets for predicting the efficacy of sublingual immunotherapy against pollen-induced allergic rhinitis.

Gotoh M, Kaminuma O, Nakaya A, Katayama K, Motoi Y, Watanabe N, Saeki M, Nishimura T, Kitamura N, Yamaoka K, Okubo K, Hiroi T.

Int Immunol. 2017 Jun 1;29(6):291-300. doi: 10.1093/intimm/dxx034.

PMID:
28575522
22.

Hyper-reactive cloned mice generated by direct nuclear transfer of antigen-specific CD4+ T cells.

Kaminuma O, Katayama K, Inoue K, Saeki M, Nishimura T, Kitamura N, Shimo Y, Tofukuji S, Ishida S, Ogonuki N, Kamimura S, Oikawa M, Katoh S, Mori A, Shichijo M, Hiroi T, Ogura A.

EMBO Rep. 2017 Jun;18(6):885-893. doi: 10.15252/embr.201643321. Epub 2017 May 2.

23.

Functional characterization of the neuron-restrictive silencer element in the human tryptophan hydroxylase 2 gene expression.

Nawa Y, Kaneko H, Oda M, Tsubonoya M, Hiroi T, Gentile MT, Colucci-D'Amato L, Takahashi R, Matsui H.

J Neurochem. 2017 Sep;142(6):827-840. doi: 10.1111/jnc.14060. Epub 2017 Jun 13.

24.

Role of the local structure in superconductivity of LaO0.5F0.5BiS2-x Se x system.

Paris E, Mizuguchi Y, Hacisalihoglu MY, Hiroi T, Joseph B, Aquilanti G, Miura O, Mizokawa T, Saini NL.

J Phys Condens Matter. 2017 Apr 12;29(14):145603. doi: 10.1088/1361-648X/aa5e97. Epub 2017 Feb 6.

PMID:
28165329
25.
26.

Th9 cells elicit eosinophil-independent bronchial hyperresponsiveness in mice.

Saeki M, Kaminuma O, Nishimura T, Kitamura N, Mori A, Hiroi T.

Allergol Int. 2016 Sep;65 Suppl:S24-9. doi: 10.1016/j.alit.2016.05.003. Epub 2016 Jun 11.

27.

Critical role of CD44 in antigen-induced Th2- but not Th17-madiated murine airway inflammation.

Nishimura T, Katoh S, Mori A, Ohtomo T, Saeki M, Hiroi T, Kaminuma O.

Allergol Int. 2016 Sep;65 Suppl:S59-61. doi: 10.1016/j.alit.2016.04.010. Epub 2016 Jul 7. No abstract available.

28.

Induced Treg Cells Augment the Th17-Mediated Intestinal Inflammatory Response in a CTLA4-Dependent Manner.

Watanabe N, Kaminuma O, Kitamura N, Hiroi T.

PLoS One. 2016 Mar 7;11(3):e0150244. doi: 10.1371/journal.pone.0150244. eCollection 2016.

29.

Effects of Dendritic Cell Subset Manipulation on Airway Allergy in a Mouse Model.

Murakami R, Nakagawa Y, Shimizu M, Wakabayashi A, Negishi Y, Hiroi T, Okubo K, Takahashi H.

Int Arch Allergy Immunol. 2015;168(4):219-32. doi: 10.1159/000443237. Epub 2016 Feb 9.

30.

Essential Contribution of CD4+ T Cells to Antigen-Induced Nasal Hyperresponsiveness in Experimental Allergic Rhinitis.

Nishimura T, Kaminuma O, Saeki M, Kitamura N, Matsuoka K, Yonekawa H, Mori A, Hiroi T.

PLoS One. 2016 Jan 11;11(1):e0146686. doi: 10.1371/journal.pone.0146686. eCollection 2016.

31.

[A biomarker set relation to the efficacy of allergen-specific immunotherapy].

Kaminuma O, Gotoh M, Nakaya A, Okubo K, Hiroi T.

Nihon Yakurigaku Zasshi. 2015 Nov;146(5):259-62. doi: 10.1254/fpj.146.259. Japanese. No abstract available.

PMID:
26558310
32.

Janus Kinase Inhibitor Tofacitinib Shows Potent Efficacy in a Mouse Model of Autoimmune Lymphoproliferative Syndrome (ALPS).

Yokoyama S, Perera PY, Terawaki S, Watanabe N, Kaminuma O, Waldmann TA, Hiroi T, Perera LP.

J Clin Immunol. 2015 Oct;35(7):661-7. doi: 10.1007/s10875-015-0203-z. Epub 2015 Oct 9.

PMID:
26453583
33.

In-plane chemical pressure essential for superconductivity in BiCh2-based (Ch: S, Se) layered structure.

Mizuguchi Y, Miura A, Kajitani J, Hiroi T, Miura O, Tadanaga K, Kumada N, Magome E, Moriyoshi C, Kuroiwa Y.

Sci Rep. 2015 Oct 8;5:14968. doi: 10.1038/srep14968.

34.

Reliable Hydrogel with Mechanical "Fuse Link" in an Aqueous Environment.

Kondo S, Hiroi T, Han YS, Kim TH, Shibayama M, Chung UI, Sakai T.

Adv Mater. 2015 Dec 2;27(45):7407-11. doi: 10.1002/adma.201503130. Epub 2015 Oct 7.

PMID:
26443000
35.

TCRβ repertoire of CD4+ and CD8+ T cells is distinct in richness, distribution, and CDR3 amino acid composition.

Li HM, Hiroi T, Zhang Y, Shi A, Chen G, De S, Metter EJ, Wood WH 3rd, Sharov A, Milner JD, Becker KG, Zhan M, Weng NP.

J Leukoc Biol. 2016 Mar;99(3):505-13. doi: 10.1189/jlb.6A0215-071RR. Epub 2015 Sep 22.

36.

Rice seed for delivery of vaccines to gut mucosal immune tissues.

Takaiwa F, Wakasa Y, Takagi H, Hiroi T.

Plant Biotechnol J. 2015 Oct;13(8):1041-55. doi: 10.1111/pbi.12423. Epub 2015 Jun 23. Review.

37.

Analysis of the effects of dietary fat on body and skin lipids of hamsters by Raman spectroscopy.

Meksiarun P, Maeda Y, Hiroi T, Andriana BB, Sato H.

Analyst. 2015 Jun 21;140(12):4238-44. doi: 10.1039/c5an00076a. Epub 2015 Apr 29.

PMID:
25920444
38.

Effects of natural nuclear factor-kappa B inhibitors on anticancer drug efflux transporter human P-glycoprotein.

Nabekura T, Hiroi T, Kawasaki T, Uwai Y.

Biomed Pharmacother. 2015 Mar;70:140-5. doi: 10.1016/j.biopha.2015.01.007. Epub 2015 Jan 15.

PMID:
25776492
39.

Concentrated protein body product derived from rice endosperm as an oral tolerogen for allergen-specific immunotherapy--a new mucosal vaccine formulation against Japanese cedar pollen allergy.

Wakasa Y, Takagi H, Watanabe N, Kitamura N, Fujiwara Y, Ogo Y, Hayashi S, Yang L, Ohta M, Thet Tin WW, Sekikawa K, Takano M, Ozawa K, Hiroi T, Takaiwa F.

PLoS One. 2015 Mar 16;10(3):e0120209. doi: 10.1371/journal.pone.0120209. eCollection 2015.

40.

Tumor-secreted miR-214 induces regulatory T cells: a major link between immune evasion and tumor growth.

Yin Y, Cai X, Chen X, Liang H, Zhang Y, Li J, Wang Z, Chen X, Zhang W, Yokoyama S, Wang C, Li L, Li L, Hou D, Dong L, Xu T, Hiroi T, Yang F, Ji H, Zhang J, Zen K, Zhang CY.

Cell Res. 2014 Oct;24(10):1164-80. doi: 10.1038/cr.2014.121. Epub 2014 Sep 16.

41.

IL-17A induces hypo-contraction of intestinal smooth muscle via induction of iNOS in muscularis macrophages.

Mori D, Watanabe N, Kaminuma O, Murata T, Hiroi T, Ozaki H, Hori M.

J Pharmacol Sci. 2014;125(4):394-405. Epub 2014 Jul 25.

42.

Food Allergen-induced IgE Response Mouse Model Created by Injection of in vitro Differentiated Th2 Cell Culture and Oral Antigen Intake.

Shibahara K, Nakajima-Adachi H, Kaminuma O, Hiroi T, Mori A, Hachimura S.

Biosci Microbiota Food Health. 2014;33(1):41-6. doi: 10.12938/bmfh.33.41. Epub 2014 Jan 30.

43.

Antigen-induced mixed and separated inflammation in murine upper and lower airways.

Saeki M, Nishimura T, Mori A, Kaminuma O, Hiroi T.

Allergol Int. 2014 May;63 Suppl 1:59-61. doi: 10.2332/allergolint.13-LE-0634. No abstract available.

44.

Selective suppression of Th2 cell-mediated lung eosinophilic inflammation by anti-major facilitator super family domain containing 10 monoclonal antibody.

Nishimura T, Saeki M, Motoi Y, Kitamura N, Mori A, Kaminuma O, Hiroi T.

Allergol Int. 2014 May;63 Suppl 1:29-35. doi: 10.2332/allergolint.13-OA-0635.

45.

A gene cluster for the synthesis of serotype g-specific polysaccharide antigen in Aggregatibacter actinomycetemcomitans.

Tsuzukibashi O, Saito M, Kobayashi T, Umezawa K, Nagahama F, Hiroi T, Hirasawa M, Takada K.

Arch Microbiol. 2014 Apr;196(4):261-5. doi: 10.1007/s00203-014-0965-3. Epub 2014 Feb 22.

PMID:
24562973
46.

Development of an immunochromatographic test strip for detection of cholera toxin.

Yamasaki E, Sakamoto R, Matsumoto T, Morimatsu F, Kurazono T, Hiroi T, Nair GB, Kurazono H.

Biomed Res Int. 2013;2013:679038. doi: 10.1155/2013/679038. Epub 2013 Nov 7.

47.

Chelyabinsk airburst, damage assessment, meteorite recovery, and characterization.

Popova OP, Jenniskens P, Emel'yanenko V, Kartashova A, Biryukov E, Khaibrakhmanov S, Shuvalov V, Rybnov Y, Dudorov A, Grokhovsky VI, Badyukov DD, Yin QZ, Gural PS, Albers J, Granvik M, Evers LG, Kuiper J, Kharlamov V, Solovyov A, Rusakov YS, Korotkiy S, Serdyuk I, Korochantsev AV, Larionov MY, Glazachev D, Mayer AE, Gisler G, Gladkovsky SV, Wimpenny J, Sanborn ME, Yamakawa A, Verosub KL, Rowland DJ, Roeske S, Botto NW, Friedrich JM, Zolensky ME, Le L, Ross D, Ziegler K, Nakamura T, Ahn I, Lee JI, Zhou Q, Li XH, Li QL, Liu Y, Tang GQ, Hiroi T, Sears D, Weinstein IA, Vokhmintsev AS, Ishchenko AV, Schmitt-Kopplin P, Hertkorn N, Nagao K, Haba MK, Komatsu M, Mikouchi T; Chelyabinsk Airburst Consortium.

Science. 2013 Nov 29;342(6162):1069-73. doi: 10.1126/science.1242642. Epub 2013 Nov 7.

48.

Dynamic light scattering microscope: accessing opaque samples with high spatial resolution.

Hiroi T, Shibayama M.

Opt Express. 2013 Aug 26;21(17):20260-7. doi: 10.1364/OE.21.020260.

PMID:
24105571
49.

The proteasome inhibitor bortezomib inhibits the growth of canine malignant melanoma cells in vitro and in vivo.

Ito K, Kobayashi M, Kuroki S, Sasaki Y, Iwata T, Mori K, Kuroki T, Ozawa Y, Tetsuka M, Nakagawa T, Hiroi T, Yamamoto H, Ono K, Washizu T, Bonkobara M.

Vet J. 2013 Dec;198(3):577-82. doi: 10.1016/j.tvjl.2013.08.003. Epub 2013 Aug 11.

PMID:
24035468
50.

Protective-antigen (PA) based anthrax vaccines confer protection against inhalation anthrax by precluding the establishment of a systemic infection.

Merkel TJ, Perera PY, Lee GM, Verma A, Hiroi T, Yokote H, Waldmann TA, Perera LP.

Hum Vaccin Immunother. 2013 Sep;9(9):1841-8. doi: 10.4161/hv.25337. Epub 2013 Jun 20.

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