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Items: 1 to 50 of 174

1.

Bif-1/Endophilin B1/SH3GLB1 regulates bone homeostasis.

Touyama K, Khan M, Aoki K, Matsuda M, Hiura F, Takakura N, Matsubara T, Harada Y, Hirohashi Y, Tamura Y, Gao J, Mori K, Kokabu S, Yasuda H, Fujita Y, Watanabe K, Takahashi Y, Maki K, Jimi E.

J Cell Biochem. 2019 Nov;120(11):18793-18804. doi: 10.1002/jcb.29193. Epub 2019 Jun 26.

PMID:
31243813
2.

Randomized phase II trial of survivin 2B peptide vaccination for patients with HLA-A24-positive pancreatic adenocarcinoma.

Shima H, Tsurita G, Wada S, Hirohashi Y, Yasui H, Hayashi H, Miyakoshi T, Watanabe K, Murai A, Asanuma H, Tokita S, Kubo T, Nakatsugawa M, Kanaseki T, Tsukahara T, Nakae Y, Sugita O, Ito YM, Ota Y, Kimura Y, Kutomi G, Hirata K, Mizuguchi T, Imai K, Takemasa I, Sato N, Torigoe T.

Cancer Sci. 2019 Aug;110(8):2378-2385. doi: 10.1111/cas.14106. Epub 2019 Jul 23.

3.

Immunohistological analysis of pancreatic carcinoma after vaccination with survivin 2B peptide: Analysis of an autopsy series.

Kubo T, Tsurita G, Hirohashi Y, Yasui H, Ota Y, Watanabe K, Murai A, Matsuo K, Asanuma H, Shima H, Wada S, Nakatsugawa M, Kanaseki T, Tsukahara T, Mizuguchi T, Hirata K, Takemasa I, Imai K, Sato N, Torigoe T.

Cancer Sci. 2019 Aug;110(8):2386-2395. doi: 10.1111/cas.14099. Epub 2019 Jul 11.

4.

[PD-L1-Mediated Immune Escape Mechanism of Cancer Stem-Like Cells].

Matsuki M, Hirohashi Y, Torigoe T.

Gan To Kagaku Ryoho. 2019 May;46(5):850-854. Review. Japanese.

PMID:
31189802
5.

Effect of interfacial serum proteins on the cell membrane disruption induced by amorphous silica nanoparticles in erythrocytes, lymphocytes, malignant melanocytes, and macrophages.

Shinto H, Fukasawa T, Yoshisue K, Tsukamoto N, Aso S, Hirohashi Y, Seto H.

Colloids Surf B Biointerfaces. 2019 Sep 1;181:270-277. doi: 10.1016/j.colsurfb.2019.05.067. Epub 2019 May 27.

PMID:
31153022
6.

ABCG2 expression is related to low 5-ALA photodynamic diagnosis (PDD) efficacy and cancer stem cell phenotype, and suppression of ABCG2 improves the efficacy of PDD.

Kawai N, Hirohashi Y, Ebihara Y, Saito T, Murai A, Saito T, Shirosaki T, Kubo T, Nakatsugawa M, Kanaseki T, Tsukahara T, Shichinohe T, Li L, Hirano S, Torigoe T.

PLoS One. 2019 May 13;14(5):e0216503. doi: 10.1371/journal.pone.0216503. eCollection 2019.

7.

Severe cytokine release syndrome resulting in purpura fulminans despite successful response to nivolumab therapy in a patient with pleomorphic carcinoma of the lung: a case report.

Honjo O, Kubo T, Sugaya F, Nishizaka T, Kato K, Hirohashi Y, Takahashi H, Torigoe T.

J Immunother Cancer. 2019 Apr 3;7(1):97. doi: 10.1186/s40425-019-0582-4.

8.

Upstream Position of Proline Defines Peptide-HLA Class I Repertoire Formation and CD8+ T Cell Responses.

Hongo A, Kanaseki T, Tokita S, Kochin V, Miyamoto S, Hashino Y, Codd A, Kawai N, Nakatsugawa M, Hirohashi Y, Sato N, Torigoe T.

J Immunol. 2019 May 15;202(10):2849-2855. doi: 10.4049/jimmunol.1900029. Epub 2019 Apr 1.

PMID:
30936292
9.

Amplification of Sensor Signals from Metal Mesh Device with Fine Periodic Structure.

Seto H, Saiki A, Kamba S, Kondo T, Hasegawa M, Miura Y, Hirohashi Y, Shinto H.

Anal Sci. 2019 Jun 10;35(6):619-623. doi: 10.2116/analsci.18P498. Epub 2019 Feb 1.

10.

Clonal analysis revealed functional heterogeneity in cancer stem-like cell phenotypes in uterine endometrioid adenocarcinoma.

Tabuchi Y, Hirohashi Y, Hashimoto S, Mariya T, Asano T, Ikeo K, Kuroda T, Mizuuchi M, Murai A, Uno S, Kawai N, Kubo T, Nakatsugawa M, Kanaseki T, Tsukahara T, Saito T, Torigoe T.

Exp Mol Pathol. 2019 Feb;106:78-88. doi: 10.1016/j.yexmp.2018.11.013. Epub 2018 Nov 30.

PMID:
30503404
11.

Occult ovarian clear-cell carcinoma diagnosed as primary adenocarcinoma of the lung: A case report of a diagnostic pitfall for clinicians and pathologists.

Kubo T, Hirohashi Y, Fujita H, Sugita S, Kikuchi Y, Shinkawa T, Nakatsugawa M, Tsujiwaki M, Sudo Y, Asai Y, Umeda Y, Takahashi H, Hasegawa T, Torigoe T.

Respir Med Case Rep. 2018 Oct 18;25:306-308. doi: 10.1016/j.rmcr.2018.10.013. eCollection 2018.

12.

Development of a T-cell receptor multimer with high avidity for detecting a naturally presented tumor-associated antigen on osteosarcoma cells.

Watanabe K, Tsukahara T, Toji S, Saitoh S, Hirohashi Y, Nakatsugawa M, Kubo T, Kanaseki T, Kameshima H, Terui T, Sato N, Torigoe T.

Cancer Sci. 2019 Jan;110(1):40-51. doi: 10.1111/cas.13854. Epub 2018 Dec 1.

13.

Differential bronchial epithelial response regulated by ΔNp63: a functional understanding of the epithelial shedding found in asthma.

Kubo T, Tsujiwaki M, Hirohashi Y, Tsukahara T, Kanaseki T, Nakatsugawa M, Hasegawa T, Torigoe T.

Lab Invest. 2019 Feb;99(2):158-168. doi: 10.1038/s41374-018-0132-6. Epub 2018 Sep 25.

PMID:
30254318
14.

Influence of PD-L1 expression in immune cells on the response to radiation therapy in patients with oropharyngeal squamous cell carcinoma.

Fukushima Y, Someya M, Nakata K, Hori M, Kitagawa M, Hasegawa T, Tsuchiya T, Gocho T, Ikeda H, Hirohashi Y, Torigoe T, Sugita S, Hasegawa T, Himi T, Sakata KI.

Radiother Oncol. 2018 Nov;129(2):409-414. doi: 10.1016/j.radonc.2018.08.023. Epub 2018 Sep 21.

PMID:
30249348
15.

Case report: Long-term survival of a pancreatic cancer patient immunized with an SVN-2B peptide vaccine.

Shima H, Kutomi G, Satomi F, Imamura M, Kimura Y, Mizuguchi T, Watanabe K, Takahashi A, Murai A, Tsukahara T, Kanaseki T, Hirohashi Y, Iwayama Y, Tsuruma T, Kameshima H, Sato N, Torigoe T, Takemasa I.

Cancer Immunol Immunother. 2018 Oct;67(10):1603-1609. doi: 10.1007/s00262-018-2217-x. Epub 2018 Aug 1.

16.

LpMab-23-recognizing cancer-type podoplanin is a novel predictor for a poor prognosis of early stage tongue cancer.

Miyazaki A, Nakai H, Sonoda T, Hirohashi Y, Kaneko MK, Kato Y, Sawa Y, Hiratsuka H.

Oncotarget. 2018 Apr 20;9(30):21156-21165. doi: 10.18632/oncotarget.24986. eCollection 2018 Apr 20.

17.

The Antigen ASB4 on Cancer Stem Cells Serves as a Target for CTL Immunotherapy of Colorectal Cancer.

Miyamoto S, Kochin V, Kanaseki T, Hongo A, Tokita S, Kikuchi Y, Takaya A, Hirohashi Y, Tsukahara T, Terui T, Ishitani K, Hata F, Takemasa I, Miyazaki A, Hiratsuka H, Sato N, Torigoe T.

Cancer Immunol Res. 2018 Mar;6(3):358-369. doi: 10.1158/2326-6066.CIR-17-0518. Epub 2018 Jan 25.

18.

ST6GALNAC1 plays important roles in enhancing cancer stem phenotypes of colorectal cancer via the Akt pathway.

Ogawa T, Hirohashi Y, Murai A, Nishidate T, Okita K, Wang L, Ikehara Y, Satoyoshi T, Usui A, Kubo T, Nakastugawa M, Kanaseki T, Tsukahara T, Kutomi G, Furuhata T, Hirata K, Sato N, Mizuguchi T, Takemasa I, Torigoe T.

Oncotarget. 2017 Nov 8;8(68):112550-112564. doi: 10.18632/oncotarget.22545. eCollection 2017 Dec 22.

19.

Cellular stress induces cancer stem-like cells through expression of DNAJB8 by activation of heat shock factor 1.

Kusumoto H, Hirohashi Y, Nishizawa S, Yamashita M, Yasuda K, Murai A, Takaya A, Mori T, Kubo T, Nakatsugawa M, Kanaseki T, Tsukahara T, Kondo T, Sato N, Hara I, Torigoe T.

Cancer Sci. 2018 Mar;109(3):741-750. doi: 10.1111/cas.13501. Epub 2018 Feb 20.

20.

Identification of antigenic peptides from novel renal cancer stem-like cell antigen, DNAJB8.

Nishizawa S, Hirohashi Y, Kusumoto H, Wakamiya T, Iguchi T, Yamashita S, Iba A, Kikkawa K, Kohjimoto Y, Torigoe T, Hara I.

Biochem Biophys Res Commun. 2017 Dec 16;494(3-4):693-699. doi: 10.1016/j.bbrc.2017.10.146. Epub 2017 Oct 28.

PMID:
29107688
21.

Comprehensive single-cell transcriptome analysis reveals heterogeneity in endometrioid adenocarcinoma tissues.

Hashimoto S, Tabuchi Y, Yurino H, Hirohashi Y, Deshimaru S, Asano T, Mariya T, Oshima K, Takamura Y, Ukita Y, Ametani A, Kondo N, Monma N, Takeda T, Misu S, Okayama T, Ikeo K, Saito T, Kaneko S, Suzuki Y, Hattori M, Matsushima K, Torigoe T.

Sci Rep. 2017 Oct 27;7(1):14225. doi: 10.1038/s41598-017-14676-3.

22.

Induction and Analysis of Cytotoxic T-Lymphocytes that Recognize Autologous Oral Squamous Cell Carcinoma.

Okamoto JY, Miyazaki A, Kobayashi JI, Miyamoto S, Sasaki T, Kanaseki T, Hirohashi Y, Torigoe T, Hiratsuka H.

Anticancer Res. 2017 Sep;37(9):4889-4897.

PMID:
28870910
23.

Elevated expression of JAM-A promotes neoplastic properties of lung adenocarcinoma.

Magara K, Takasawa A, Osanai M, Ota M, Tagami Y, Ono Y, Takasawa K, Murata M, Hirohashi Y, Miyajima M, Yamada G, Hasegawa T, Sawada N.

Cancer Sci. 2017 Nov;108(11):2306-2314. doi: 10.1111/cas.13385. Epub 2017 Sep 18.

24.

Occult Thyroid Follicular Carcinoma Diagnosed as Metastasis to the Chest Wall.

Saijo H, Kitamura Y, Takenaka H, Kudo S, Yokoo K, Hirohashi Y, Takahashi H.

Intern Med. 2017;56(15):2033-2037. doi: 10.2169/internalmedicine.56.8340. Epub 2017 Aug 1.

25.

Implication of chemo-resistant memory T cells for immune surveillance in patients with sarcoma receiving chemotherapy.

Shibayama Y, Tsukahara T, Emori M, Murata K, Mizushima E, Hirohashi Y, Kanaseki T, Nakatsugawa M, Kubo T, Yamashita T, Sato N, Torigoe T.

Cancer Sci. 2017 Sep;108(9):1739-1745. doi: 10.1111/cas.13319. Epub 2017 Aug 7.

26.

Claudin-18 coupled with EGFR/ERK signaling contributes to the malignant potentials of bile duct cancer.

Takasawa K, Takasawa A, Osanai M, Aoyama T, Ono Y, Kono T, Hirohashi Y, Murata M, Sawada N.

Cancer Lett. 2017 Sep 10;403:66-73. doi: 10.1016/j.canlet.2017.05.033. Epub 2017 Jun 15.

PMID:
28624624
27.

Identification of cancer-stem cell antigens and development of CTL-mediated cancer immunotherapy.

Miyamoto S, Kanaseki T, Hirohashi Y, Tsukahara T, Kikuchi Y, Sato N, Torigoe T.

Nihon Rinsho Meneki Gakkai Kaishi. 2017;40(1):40-47. doi: 10.2177/jsci.40.40. Review. Japanese.

28.

HLA-A24 ligandome analysis of colon and lung cancer cells identifies a novel cancer-testis antigen and a neoantigen that elicits specific and strong CTL responses.

Kochin V, Kanaseki T, Tokita S, Miyamoto S, Shionoya Y, Kikuchi Y, Morooka D, Hirohashi Y, Tsukahara T, Watanabe K, Toji S, Kokai Y, Sato N, Torigoe T.

Oncoimmunology. 2017 Feb 16;6(4):e1293214. doi: 10.1080/2162402X.2017.1293214. eCollection 2017.

29.

GRIK2 has a role in the maintenance of urothelial carcinoma stem-like cells, and its expression is associated with poorer prognosis.

Inoue R, Hirohashi Y, Kitamura H, Nishida S, Murai A, Takaya A, Yamamoto E, Matsuki M, Tanaka T, Kubo T, Nakatsugawa M, Kanaseki T, Tsukahara T, Sato N, Masumori N, Torigoe T.

Oncotarget. 2017 Apr 25;8(17):28826-28839. doi: 10.18632/oncotarget.16259.

30.

Phosphorylation of HSF1 at serine 326 residue is related to the maintenance of gynecologic cancer stem cells through expression of HSP27.

Yasuda K, Hirohashi Y, Mariya T, Murai A, Tabuchi Y, Kuroda T, Kusumoto H, Takaya A, Yamamoto E, Kubo T, Nakatsugawa M, Kanaseki T, Tsukahara T, Tamura Y, Hirano H, Hasegawa T, Saito T, Sato N, Torigoe T.

Oncotarget. 2017 May 9;8(19):31540-31553. doi: 10.18632/oncotarget.16361.

31.

Loss of tapasin in human lung and colon cancer cells and escape from tumor-associated antigen-specific CTL recognition.

Shionoya Y, Kanaseki T, Miyamoto S, Tokita S, Hongo A, Kikuchi Y, Kochin V, Watanabe K, Horibe R, Saijo H, Tsukahara T, Hirohashi Y, Takahashi H, Sato N, Torigoe T.

Oncoimmunology. 2017 Jan 3;6(2):e1274476. doi: 10.1080/2162402X.2016.1274476. eCollection 2017.

32.

Mismatch Repair Protein Deficiency Is a Risk Factor for Aberrant Expression of HLA Class I Molecules: A Putative "Adaptive Immune Escape" Phenomenon.

Kubo T, Hirohashi Y, Matsuo K, Sonoda T, Sakamoto H, Furumura K, Tsukahara T, Kanaseki T, Nakatsugawa M, Hirano H, Furuhata T, Takemasa I, Hasegawa T, Torigoe T.

Anticancer Res. 2017 Mar;37(3):1289-1295.

PMID:
28314294
33.

Brother of the regulator of the imprinted site (BORIS) variant subfamily 6 is a novel target of lung cancer stem-like cell immunotherapy.

Horibe R, Hirohashi Y, Asano T, Mariya T, Suzuki T, Takaya A, Saijo H, Shionoya Y, Kubo T, Nakatsugawa M, Kanaseki T, Tsukahara T, Watanabe K, Atsuyama E, Toji S, Hirano H, Hasegawa T, Takahashi H, Sato N, Torigoe T.

PLoS One. 2017 Mar 1;12(3):e0171460. doi: 10.1371/journal.pone.0171460. eCollection 2017.

34.

LY6/PLAUR domain containing 3 has a role in the maintenance of colorectal cancer stem-like cells.

Wang L, Hirohashi Y, Ogawa T, Shen M, Takeda R, Murai A, Yamamoto E, Kubo T, Nakatsugawa M, Kanaseki T, Tsukahara T, Nishidate T, Okita K, Kutomi G, Sato N, Takemasa I, Torigoe T.

Biochem Biophys Res Commun. 2017 Apr 29;486(2):232-238. doi: 10.1016/j.bbrc.2017.02.112. Epub 2017 Feb 24.

PMID:
28238780
35.

Identification and functional analysis of variants of a cancer/testis antigen LEMD1 in colorectal cancer stem-like cells.

Takeda R, Hirohashi Y, Shen M, Wang L, Ogawa T, Murai A, Yamamoto E, Kubo T, Nakatsugawa M, Kanaseki T, Tsukahara T, Nishidate T, Okita K, Kutomi G, Sato N, Takemasa I, Torigoe T.

Biochem Biophys Res Commun. 2017 Apr 8;485(3):651-657. doi: 10.1016/j.bbrc.2017.02.081. Epub 2017 Feb 20.

PMID:
28219643
36.

Cancer-associated oxidoreductase ERO1-α promotes immune escape through up-regulation of PD-L1 in human breast cancer.

Tanaka T, Kutomi G, Kajiwara T, Kukita K, Kochin V, Kanaseki T, Tsukahara T, Hirohashi Y, Torigoe T, Okamoto Y, Hirata K, Sato N, Tamura Y.

Oncotarget. 2017 Apr 11;8(15):24706-24718. doi: 10.18632/oncotarget.14960.

37.

Development of next-generation peptide vaccination therapy.

Tsukahara T, Hirohashi Y, Emori M, Torigoe T.

Nihon Rinsho. 2017 Feb;75(2):270-274. Japanese.

PMID:
30562863
38.

Dendritic cell and cancer immune checkpoint.

Kubo T, Hirohashi Y, Torigoe T.

Nihon Rinsho Meneki Gakkai Kaishi. 2016;39(5):468-472. Review. Japanese.

39.

Hypoxia augments MHC class I antigen presentation via facilitation of ERO1-α-mediated oxidative folding in murine tumor cells.

Kajiwara T, Tanaka T, Kukita K, Kutomi G, Saito K, Okuya K, Takaya A, Kochin V, Kanaseki T, Tsukahara T, Hirohashi Y, Torigoe T, Hirata K, Sato N, Tamura Y.

Eur J Immunol. 2016 Dec;46(12):2842-2851. doi: 10.1002/eji.201646525. Epub 2016 Oct 18.

40.

Identification of a novel human memory T-cell population with the characteristics of stem-like chemo-resistance.

Murata K, Tsukahara T, Emori M, Shibayama Y, Mizushima E, Matsumiya H, Yamashita K, Kaya M, Hirohashi Y, Kanaseki T, Kubo T, Himi T, Ichimiya S, Yamashita T, Sato N, Torigoe T.

Oncoimmunology. 2016 Jun 8;5(6):e1165376. doi: 10.1080/2162402X.2016.1165376. eCollection 2016 Jun.

41.

Peptide vaccination therapy: Towards the next generation.

Tsukahara T, Hirohashi Y, Kanaseki T, Nakatsugawa M, Kubo T, Sato N, Torigoe T.

Pathol Int. 2016 Oct;66(10):547-553. doi: 10.1111/pin.12438. Epub 2016 Jul 19. Review.

PMID:
27435148
42.

Non-neoplastic Fallopian Tube Epithelium Carrying Gene Mutations of a Novel SOX2 Repressor Region is Soil of High-grade Serous Ovarian Cancer.

Hirohashi Y, Torigoe T.

EBioMedicine. 2016 Aug;10:17-8. doi: 10.1016/j.ebiom.2016.07.009. Epub 2016 Jul 10. No abstract available.

43.

Plasticity of lung cancer stem-like cells is regulated by the transcription factor HOXA5 that is induced by oxidative stress.

Saijo H, Hirohashi Y, Torigoe T, Horibe R, Takaya A, Murai A, Kubo T, Kajiwara T, Tanaka T, Shionoya Y, Yamamoto E, Maruyama R, Nakatsugawa M, Kanaseki T, Tsukahara T, Tamura Y, Sasaki Y, Tokino T, Suzuki H, Kondo T, Takahashi H, Sato N.

Oncotarget. 2016 Aug 2;7(31):50043-50056. doi: 10.18632/oncotarget.10571.

44.

Establishment and Analysis of Cancer Stem-Like and Non-Cancer Stem-Like Clone Cells from the Human Colon Cancer Cell Line SW480.

Takaya A, Hirohashi Y, Murai A, Morita R, Saijo H, Yamamoto E, Kubo T, Nakatsugawa M, Kanaseki T, Tsukahara T, Tamura Y, Takemasa I, Kondo T, Sato N, Torigoe T.

PLoS One. 2016 Jul 14;11(7):e0158903. doi: 10.1371/journal.pone.0158903. eCollection 2016.

45.

SOX2 and ALDH1 as Predictors of Operable Breast Cancer.

Shima H, Kutomi G, Satomi F, Maeda H, Hirohashi Y, Hasegawa T, Mori M, Torigoe T, Takemasa I.

Anticancer Res. 2016 Jun;36(6):2945-53.

PMID:
27272809
46.

The future of immunotherapy for sarcoma.

Tsukahara T, Emori M, Murata K, Mizushima E, Shibayama Y, Kubo T, Kanaseki T, Hirohashi Y, Yamashita T, Sato N, Torigoe T.

Expert Opin Biol Ther. 2016 Aug;16(8):1049-57. doi: 10.1080/14712598.2016.1188075. Epub 2016 May 27. Review.

PMID:
27158940
47.

A novel nuclear DnaJ protein, DNAJC8, can suppress the formation of spinocerebellar ataxia 3 polyglutamine aggregation in a J-domain independent manner.

Ito N, Kamiguchi K, Nakanishi K, Sokolovskya A, Hirohashi Y, Tamura Y, Murai A, Yamamoto E, Kanaseki T, Tsukahara T, Kochin V, Chiba S, Shimohama S, Sato N, Torigoe T.

Biochem Biophys Res Commun. 2016 Jun 10;474(4):626-633. doi: 10.1016/j.bbrc.2016.03.152. Epub 2016 Apr 28.

PMID:
27133716
48.

Cancer-associated oxidoreductase ERO1-α drives the production of VEGF via oxidative protein folding and regulating the mRNA level.

Tanaka T, Kutomi G, Kajiwara T, Kukita K, Kochin V, Kanaseki T, Tsukahara T, Hirohashi Y, Torigoe T, Okamoto Y, Hirata K, Sato N, Tamura Y.

Br J Cancer. 2016 May 24;114(11):1227-34. doi: 10.1038/bjc.2016.105. Epub 2016 Apr 21.

49.

Matrix metalloproteinase-10 regulates stemness of ovarian cancer stem-like cells by activation of canonical Wnt signaling and can be a target of chemotherapy-resistant ovarian cancer.

Mariya T, Hirohashi Y, Torigoe T, Tabuchi Y, Asano T, Saijo H, Kuroda T, Yasuda K, Mizuuchi M, Saito T, Sato N.

Oncotarget. 2016 May 3;7(18):26806-22. doi: 10.18632/oncotarget.8645.

50.

Wound healing delays in α-Klotho-deficient mice that have skin appearance similar to that in aged humans - Study of delayed wound healing mechanism.

Yamauchi M, Hirohashi Y, Torigoe T, Matsumoto Y, Yamashita K, Kayama M, Sato N, Yotsuyanagi T.

Biochem Biophys Res Commun. 2016 May 13;473(4):845-852. doi: 10.1016/j.bbrc.2016.03.138. Epub 2016 Mar 30.

PMID:
27037022

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