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Solar-Driven Photoelectrochemical Water Oxidation over an n-Type Lead-Titanium Oxyfluoride Anode.

Hirayama N, Nakata H, Wakayama H, Nishioka S, Kanazawa T, Kamata R, Ebato Y, Kato K, Kumagai H, Yamakata A, Oka K, Maeda K.

J Am Chem Soc. 2019 Oct 30;141(43):17158-17165. doi: 10.1021/jacs.9b06570. Epub 2019 Oct 17.


A pull-down and slot blot-based screening system for inhibitor compounds of the podoplanin-CLEC-2 interaction.

Watanabe N, Kidokoro M, Suzuki Y, Tanaka M, Inoue S, Tsukamoto H, Hirayama N, Hsieh PW, Tseng CP, Nakagawa Y, Inokuchi S.

PLoS One. 2019 Sep 25;14(9):e0222331. doi: 10.1371/journal.pone.0222331. eCollection 2019.


Substitutional and interstitial impurity p-type doping of thermoelectric Mg2Si: a theoretical study.

Hirayama N, Iida T, Sakamoto M, Nishio K, Hamada N.

Sci Technol Adv Mater. 2019 Mar 14;20(1):160-172. doi: 10.1080/14686996.2019.1580537. eCollection 2019.


Early weaning increases anxiety via brain-derived neurotrophic factor signaling in the mouse prefrontal cortex.

Kikusui T, Kanbara N, Ozaki M, Hirayama N, Ida K, Tokita M, Tanabe N, Mitsuyama K, Abe H, Yoshida M, Nagasawa M, Mogi K.

Sci Rep. 2019 Mar 8;9(1):3991. doi: 10.1038/s41598-019-40530-9.


Formation of high molecular weight p62 by CORM-3.

Aki T, Unuma K, Noritake K, Hirayama N, Funakoshi T, Uemura K.

PLoS One. 2019 Jan 8;14(1):e0210474. doi: 10.1371/journal.pone.0210474. eCollection 2019.


Effects of interleukin-17A in nucleus pulposus cells and its small-molecule inhibitors for intervertebral disc disease.

Suyama K, Sakai D, Hirayama N, Nakamura Y, Matsushita E, Terayama H, Qu N, Tanaka O, Sakabe K, Watanabe M.

J Cell Mol Med. 2018 Nov;22(11):5539-5551. doi: 10.1111/jcmm.13828. Epub 2018 Sep 11.


Formation of Minimal Third Phase in Ionic Liquid Extraction System with Trioctylphosphine Oxide and Its Possible Application to Extraction Concentration.

Toita M, Morita K, Hirayama N.

Anal Sci. 2018 Sep 10;34(9):1063-1065. doi: 10.2116/analsci.18C016. Epub 2018 Aug 17.


Screening for 15 pathogenic viruses in human cell lines registered at the JCRB Cell Bank: characterization of in vitro human cells by viral infection.

Shioda S, Kasai F, Watanabe K, Kawakami K, Ohtani A, Iemura M, Ozawa M, Arakawa A, Hirayama N, Kawaguchi E, Tano T, Miyata S, Satoh M, Shimizu N, Kohara A.

R Soc Open Sci. 2018 May 2;5(5):172472. doi: 10.1098/rsos.172472. eCollection 2018 May.


Interaction of Nevirapine with the Peptide Binding Groove of HLA-DRB1*01:01 and Its Effect on the Conformation of HLA-Peptide Complex.

Hirasawa M, Hagihara K, Abe K, Ando O, Hirayama N.

Int J Mol Sci. 2018 Jun 4;19(6). pii: E1660. doi: 10.3390/ijms19061660.


HuH-7 reference genome profile: complex karyotype composed of massive loss of heterozygosity.

Kasai F, Hirayama N, Ozawa M, Satoh M, Kohara A.

Hum Cell. 2018 Jul;31(3):261-267. doi: 10.1007/s13577-018-0212-3. Epub 2018 May 17.


Necrosis in human neuronal cells exposed to paraquat.

Hirayama N, Aki T, Funakoshi T, Noritake K, Unuma K, Uemura K.

J Toxicol Sci. 2018;43(3):193-202. doi: 10.2131/jts.43.193.


Severe and Recurrent Hypoglycemia Caused by Garenoxacin in a Patient not Taking Hypoglycemic Drugs.

Kondo M, Miyoshi Y, Tarumoto K, Hirayama N, Sasaki T, Yamashita K, Yamashita S, Hatao K.

Intern Med. 2018 Jul 15;57(14):2041-2043. doi: 10.2169/internalmedicine.0366-17. Epub 2018 Feb 28.


Effect of the Elemental Composition of Precursors from Amino Acids and Their Binary Mixtures on the Photoluminescent Intensity of Carbon Nanodots.

Morita K, Kurusu S, Kodama H, Hirayama N.

Anal Sci. 2017;33(12):1461-1464. doi: 10.2116/analsci.33.1461.


TGF-╬▓-induced intracellular PAI-1 is responsible for retaining hematopoietic stem cells in the niche.

Yahata T, Ibrahim AA, Muguruma Y, Eren M, Shaffer AM, Watanabe N, Kaneko S, Nakabayashi T, Dan T, Hirayama N, Vaughan DE, Miyata T, Ando K.

Blood. 2017 Nov 23;130(21):2283-2294. doi: 10.1182/blood-2017-02-767384. Epub 2017 Aug 18.


The human vascular endothelial cell line HUV-EC-C harbors the integrated HHV-6B genome which remains stable in long term culture.

Shioda S, Kasai F, Ozawa M, Hirayama N, Satoh M, Kameoka Y, Watanabe K, Shimizu N, Tang H, Mori Y, Kohara A.

Cytotechnology. 2018 Feb;70(1):141-152. doi: 10.1007/s10616-017-0119-y. Epub 2017 Jul 28.


A cell-based high-throughput screening assay system for inhibitor compounds of antigen presentation by HLA class II molecule.

Watanabe N, Suzuki Y, Yonezu T, Nakagawa Y, Shiina T, Hirayama N, Inokuchi S, Inoue S.

Sci Rep. 2017 Jul 28;7(1):6798. doi: 10.1038/s41598-017-07080-4.


Immobility responses are induced by photoactivation of single glomerular species responsive to fox odour TMT.

Saito H, Nishizumi H, Suzuki S, Matsumoto H, Ieki N, Abe T, Kiyonari H, Morita M, Yokota H, Hirayama N, Yamazaki T, Kikusui T, Mori K, Sakano H.

Nat Commun. 2017 Jul 7;8:16011. doi: 10.1038/ncomms16011.


In Silico and In Vitro Analysis of Interaction between Ximelagatran and Human Leukocyte Antigen (HLA)-DRB1*07:01.

Hirasawa M, Hagihara K, Abe K, Ando O, Hirayama N.

Int J Mol Sci. 2017 Mar 24;18(4). pii: E694. doi: 10.3390/ijms18040694.


Docking simulations between drugs and HLA molecules associated with idiosyncratic drug toxicity.

Hirayama N.

Drug Metab Pharmacokinet. 2017 Feb;32(1):31-39. doi: 10.1016/j.dmpk.2016.10.002. Epub 2016 Oct 18. Review.


Production of a Locus- and Allele-Specific Monoclonal Antibody for the Characterization of SLA-1*0401 mRNA and Protein Expression Levels in MHC-Defined Microminipigs.

Kametani Y, Ohshima S, Miyamoto A, Shigenari A, Takasu M, Imaeda N, Matsubara T, Tanaka M, Shiina T, Kamiguchi H, Suzuki R, Kitagawa H, Kulski JK, Hirayama N, Inoko H, Ando A.

PLoS One. 2016 Oct 19;11(10):e0164995. doi: 10.1371/journal.pone.0164995. eCollection 2016.


Binding Affinity and Interaction of LL-37 with HLA-C*06:02 in Psoriasis.

Mabuchi T, Hirayama N.

J Invest Dermatol. 2016 Sep;136(9):1901-1903. doi: 10.1016/j.jid.2016.04.033. Epub 2016 May 14. No abstract available.


Changes of heterogeneous cell populations in the Ishikawa cell line during long-term culture: Proposal for an in vitro clonal evolution model of tumor cells.

Kasai F, Hirayama N, Ozawa M, Iemura M, Kohara A.

Genomics. 2016 Jun;107(6):259-66. doi: 10.1016/j.ygeno.2016.04.003. Epub 2016 Apr 20.


Cytotoxicity associated with prolonged room temperature storage of serum and proposed methods for reduction of cytotoxicity.

Shiraishi R, Hirayama N.

J Virol Methods. 2015 Dec 1;225:16-22. doi: 10.1016/j.jviromet.2015.08.018. Epub 2015 Sep 1.


The genome landscape of the african green monkey kidney-derived vero cell line.

Osada N, Kohara A, Yamaji T, Hirayama N, Kasai F, Sekizuka T, Kuroda M, Hanada K.

DNA Res. 2014 Dec;21(6):673-83. doi: 10.1093/dnares/dsu029. Epub 2014 Sep 28.


Frequent mutations in NOTCH1 ligand-binding regions in Japanese oral squamous cell carcinoma.

Aoyama K, Ota Y, Kajiwara K, Hirayama N, Kimura M.

Biochem Biophys Res Commun. 2014 Oct 3;452(4):980-5. doi: 10.1016/j.bbrc.2014.09.021. Epub 2014 Sep 16.


Mechanical gate control for atom-by-atom cluster assembly with scanning probe microscopy.

Sugimoto Y, Yurtsever A, Hirayama N, Abe M, Morita S.

Nat Commun. 2014 Jul 11;5:4360. doi: 10.1038/ncomms5360.


[A case of advanced gastric cancer with para-aortic lymph node metastases responding to S-1/CDDP chemotherapy that leads to a pathological complete response].

Nakano A, Endo M, Hirayama N, Akai T, Matsubara H.

Gan To Kagaku Ryoho. 2014 May;41(5):641-3. Japanese.


Methotrexate and gemcitabine combination chemotherapy for the treatment of malignant pleural mesothelioma.

Kuribayashi K, Miyata S, Fukuoka K, Murakami A, Yamada S, Tamura K, Hirayama N, Terada T, Tabata C, Fujimori Y, Nakano T.

Mol Clin Oncol. 2013 Jul;1(4):639-642. Epub 2013 May 10.


A novel acylaminoimidazole derivative, WN1316, alleviates disease progression via suppression of glial inflammation in ALS mouse model.

Tanaka K, Kanno T, Yanagisawa Y, Yasutake K, Inoue S, Hirayama N, Ikeda JE.

PLoS One. 2014 Jan 31;9(1):e87728. doi: 10.1371/journal.pone.0087728. eCollection 2014.


Determination of critical factors causing cytotoxicity in the virus neutralization test.

Shiraishi R, Nishimura M, Nakashima R, Enta C, Hirayama N.

J Virol Methods. 2014 Apr;199:46-52. doi: 10.1016/j.jviromet.2014.01.006. Epub 2014 Jan 22.


Neutralizing antibody response in dogs and cats inoculated with commercial inactivated rabies vaccines.

Shiraishi R, Nishimura M, Nakashima R, Enta C, Hirayama N.

J Vet Med Sci. 2014 Apr;76(4):605-9. Epub 2013 Dec 31.


In Silico Risk Assessment of HLA-A*02:06-Associated Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis Caused by Cold Medicine Ingredients.

Isogai H, Miyadera H, Ueta M, Sotozono C, Kinoshita S, Tokunaga K, Hirayama N.

J Toxicol. 2013;2013:514068. doi: 10.1155/2013/514068. Epub 2013 Oct 12.


Na+/H+ exchanger 1 is regulated via its lipid-interacting domain, which functions as a molecular switch: a pharmacological approach using indolocarbazole compounds.

Shimada-Shimizu N, Hisamitsu T, Nakamura TY, Hirayama N, Wakabayashi S.

Mol Pharmacol. 2014 Jan;85(1):18-28. doi: 10.1124/mol.113.089268. Epub 2013 Oct 17.


Efficacy of alogliptin, a dipeptidyl peptidase-4 inhibitor, on glucose parameters, the activity of the advanced glycation end product (AGE) - receptor for AGE (RAGE) axis and albuminuria in Japanese type 2 diabetes.

Sakata K, Hayakawa M, Yano Y, Tamaki N, Yokota N, Eto T, Watanabe R, Hirayama N, Matsuo T, Kuroki K, Sagara S, Mishima O, Koga M, Nagata N, Nishino Y, Kitamura K, Kario K, Takeuchi M, Yamagishi S.

Diabetes Metab Res Rev. 2013 Nov;29(8):624-30. doi: 10.1002/dmrr.2437.


10-MHz, Yb-fiber chirped-pulse amplifier system with large-scale transmission gratings.

Kobayashi Y, Hirayama N, Ozawa A, Sukegawa T, Seki T, Kuramoto Y, Watanabe S.

Opt Express. 2013 May 20;21(10):12865-73. doi: 10.1364/OE.21.012865.


50-Gb/s ring-resonator-based silicon modulator.

Baba T, Akiyama S, Imai M, Hirayama N, Takahashi H, Noguchi Y, Horikawa T, Usuki T.

Opt Express. 2013 May 20;21(10):11869-76. doi: 10.1364/OE.21.011869.


In Silico Prediction of Interactions between Site II on Human Serum Albumin and Profen Drugs.

Isogai H, Hirayama N.

ISRN Pharm. 2013;2013:818364. doi: 10.1155/2013/818364. Epub 2013 Mar 6.


Prevalence and molecular epidemiological characterization of antimicrobial-resistant Escherichia coli isolates from Japanese black beef cattle.

Yamamoto S, Iwabuchi E, Hasegawa M, Esaki H, Muramatsu M, Hirayama N, Hirai K.

J Food Prot. 2013 Mar;76(3):394-404. doi: 10.4315/0362-028X.JFP-12-273.


Protein kinase C regulates human pluripotent stem cell self-renewal.

Kinehara M, Kawamura S, Tateyama D, Suga M, Matsumura H, Mimura S, Hirayama N, Hirata M, Uchio-Yamada K, Kohara A, Yanagihara K, Furue MK.

PLoS One. 2013;8(1):e54122. doi: 10.1371/journal.pone.0054122. Epub 2013 Jan 21.


Eleven pairs of Japanese male twins suggest the role of epigenetic differences in androgenetic alopecia.

Koyama T, Kobayashi K, Wakisaka N, Hirayama N, Konishi S, Hama T, Takeda K, Nakamizo Y, Kawakami M.

Eur J Dermatol. 2013 Jan-Feb;23(1):113-5. doi: 10.1684/ejd.2012.1898. No abstract available.


Valence discriminative detection of metal cations by a chromotropic acid-grafted glassy carbon electrode.

Morita K, Shibata K, Nagatani H, Hirayama N, Imura H.

Anal Sci. 2013;29(1):95-9.


A possible molecular mechanism of immunomodulatory activity of bilirubin.

Isogai H, Hirayama N.

Int J Med Chem. 2013;2013:467383. doi: 10.1155/2013/467383. Epub 2013 Apr 9.


HLA-Modeler: Automated Homology Modeling of Human Leukocyte Antigens.

Amari S, Kataoka R, Ikegami T, Hirayama N.

Int J Med Chem. 2013;2013:690513. doi: 10.1155/2013/690513. Epub 2013 Nov 27.


Demonstration of 12.5-Gbps optical interconnects integrated with lasers, optical splitters, optical modulators and photodetectors on a single silicon substrate.

Urino Y, Noguchi Y, Noguchi M, Imai M, Yamagishi M, Saitou S, Hirayama N, Takahashi M, Takahashi H, Saito E, Okano M, Shimizu T, Hatori N, Ishizaka M, Yamamoto T, Baba T, Akagawa T, Akiyama S, Usuki T, Okamoto D, Miura M, Fujikata J, Shimura D, Okayama H, Yaegashi H, Tsuchizawa T, Yamada K, Mori M, Horikawa T, Nakamura T, Arakawa Y.

Opt Express. 2012 Dec 10;20(26):B256-63. doi: 10.1364/OE.20.00B256.


Specific cooperative effect of a macrocyclic receptor for metal ion transfer into an ionic liquid.

Okamura H, Ikeda-Ohno A, Saito T, Aoyagi N, Naganawa H, Hirayama N, Umetani S, Imura H, Shimojo K.

Anal Chem. 2012 Nov 6;84(21):9332-9. doi: 10.1021/ac302015h. Epub 2012 Oct 22.


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