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Items: 1 to 50 of 128

1.

Comparison of Direct and Mediated Electron Transfer in Electrodes with Novel Fungal Flavin Adenine Dinucleotide Glucose Dehydrogenase.

Ishida K, Orihara K, Muguruma H, Iwasa H, Hiratsuka A, Tsuji K, Kishimoto T.

Anal Sci. 2018;34(7):783-787. doi: 10.2116/analsci.17P613.

2.

Procyanidins from Cinnamomi Cortex promote proteasome-independent degradation of nuclear Nrf2 through phosphorylation of insulin-like growth factor-1 receptor in A549 cells.

Ohnuma T, Sakamoto K, Shinoda A, Takagi C, Ohno S, Nishiyama T, Ogura K, Hiratsuka A.

Arch Biochem Biophys. 2017 Dec 1;635:66-73. doi: 10.1016/j.abb.2017.10.007. Epub 2017 Oct 16.

PMID:
29051069
3.

Thermophilic Talaromyces emersonii Flavin Adenine Dinucleotide-Dependent Glucose Dehydrogenase Bioanode for Biosensor and Biofuel Cell Applications.

Iwasa H, Hiratsuka A, Yokoyama K, Uzawa H, Orihara K, Muguruma H.

ACS Omega. 2017 Apr 30;2(4):1660-1665. doi: 10.1021/acsomega.7b00277. Epub 2017 Apr 26.

4.

Identification and characterization of thermostable glucose dehydrogenases from thermophilic filamentous fungi.

Ozawa K, Iwasa H, Sasaki N, Kinoshita N, Hiratsuka A, Yokoyama K.

Appl Microbiol Biotechnol. 2017 Jan;101(1):173-183. doi: 10.1007/s00253-016-7754-7. Epub 2016 Aug 10.

PMID:
27510979
5.

Selective antagonization of activated Nrf2 and inhibition of cancer cell proliferation by procyanidins from Cinnamomi Cortex extract.

Ohnuma T, Anzai E, Suzuki Y, Shimoda M, Saito S, Nishiyama T, Ogura K, Hiratsuka A.

Arch Biochem Biophys. 2015 Nov 1;585:17-24. doi: 10.1016/j.abb.2015.09.007. Epub 2015 Sep 11.

PMID:
26365032
6.

Distinct effects of dipeptidyl peptidase-4 inhibitor and glucagon-like peptide-1 receptor agonist on islet morphology and function.

Morita A, Mukai E, Hiratsuka A, Takatani T, Iwanaga T, Lee EY, Miki T.

Endocrine. 2016 Mar;51(3):429-39. doi: 10.1007/s12020-015-0733-4. Epub 2015 Sep 8.

PMID:
26349938
7.

5-Fluorouracil Chemotherapy for Dihydropyrimidine Dehydrogenase-deficient Patients: Potential of the Dose-escalation Method.

Yoshida Y, Ogura K, Hiratsuka A, Aisu N, Yamada T, Kojima D, Tanimura S, Ogata K, Hara S, Mogi A, Takamatsu Y, Tamura K, Mishima H, Yamashita Y.

Anticancer Res. 2015 Sep;35(9):4881-7.

PMID:
26254383
8.

Formation and stability of 4-(hydroxymethylnitrosamino)-1-(3-pyridyl)-1-butanone glucuronide, a stable form of reactive intermediate produced from 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, in mice.

Nishiyama T, Hayashi N, Kakurai N, Yanagita H, Kuriyama A, Miyamoto C, Ishihara Y, Ogura K, Ohnuma T, Hiratsuka A.

J Toxicol Sci. 2014 Aug;39(4):515-21.

9.

Gene expression, function, and diversity of Nkx2-4 in the rainbow trout, Oncorhynchus mykiss.

Uemae Y, Sakamoto J, Hidaka Y, Hiratsuka A, Susa T, Kato Y, Suzuki M.

Gen Comp Endocrinol. 2014 Sep 15;206:193-202. doi: 10.1016/j.ygcen.2014.07.007. Epub 2014 Jul 19.

PMID:
25051213
11.

Impact of milrinone on mitral annular velocity in patients with congestive heart failure.

Hadano Y, Ogawa H, Wakeyama T, Takaki A, Iwami T, Kimura M, Mochizuki M, Miyazaki Y, Hiratsuka A, Matsuzaki M.

J Med Ultrason (2001). 2013 Apr;40(2):111-8. doi: 10.1007/s10396-012-0405-4. Epub 2012 Oct 10.

PMID:
27277099
12.

Effects of isoproterenol infusion on the ST segment and r of the QRS complex in the right precordial leads of the Brugada-type electrocardiogram pattern--author's reply.

Shimizu A, Omiya T, Ueyama T, Yoshiga Y, Doi M, Hiratsuka A, Fukuda M, Yoshida M, Matsuzaki M, Yano M.

J Cardiol. 2013 Apr;61(4):312-3. doi: 10.1016/j.jjcc.2013.02.002. Epub 2013 Mar 14. No abstract available.

PMID:
23498027
13.

Effects of isoproterenol and propranolol on the inducibility and frequency of ventricular fibrillation in patients with Brugada syndrome.

Omiya T, Shimizu A, Ueyama T, Yoshiga Y, Doi M, Hiratsuka A, Fukuda M, Yoshida M, Matsuzaki M.

J Cardiol. 2012 Jul;60(1):47-54. doi: 10.1016/j.jjcc.2012.02.001. Epub 2012 Mar 21.

14.

Characteristics of induced ventricular fibrillation cycle length in symptomatic Brugada syndrome patients.

Hiratsuka A, Shimizu A, Ueyama T, Yoshiga Y, Doi M, Ohmiya T, Yoshida M, Fukuda M, Matsuzaki M.

Circ J. 2012;76(3):624-33. Epub 2012 Jan 17.

15.

Stable isotope dilution mass spectrometric assay for PRPP using enzymatic procedures.

Shinohara Y, Suzuki Y, Hasegawa H, Nakamura M, Nishiyama T, Hiratsuka A, Ichida K.

Nucleosides Nucleotides Nucleic Acids. 2011 Dec;30(12):1140-6. doi: 10.1080/15257770.2011.591746.

PMID:
22132968
16.

Enhanced sensitivity of A549 cells to the cytotoxic action of anticancer drugs via suppression of Nrf2 by procyanidins from Cinnamomi Cortex extract.

Ohnuma T, Matsumoto T, Itoi A, Kawana A, Nishiyama T, Ogura K, Hiratsuka A.

Biochem Biophys Res Commun. 2011 Oct 7;413(4):623-9. doi: 10.1016/j.bbrc.2011.09.014. Epub 2011 Sep 9.

PMID:
21925486
17.

Involvement of different human glutathione transferase isoforms in the glutathione conjugation of reactive metabolites of troglitazone.

Okada R, Maeda K, Nishiyama T, Aoyama S, Tozuka Z, Hiratsuka A, Ikeda T, Kusuhara H, Sugiyama Y.

Drug Metab Dispos. 2011 Dec;39(12):2290-7. doi: 10.1124/dmd.111.040469. Epub 2011 Sep 13.

18.

Design and synthesis of new fluorescent probe for rapid and highly sensitive detection of proteins via electrophoretic gel stain.

Suzuki Y, Takagi N, Chimuro T, Shinohara A, Sakaguchi N, Hiratsuka A, Yokoyama K.

Electrophoresis. 2011 Jun;32(12):1403-13. doi: 10.1002/elps.201000691.

PMID:
21692079
19.
20.

Effects of mineralocorticoid receptor antagonist spironolactone on atrial conduction and remodeling in patients with heart failure.

Kimura M, Ogawa H, Wakeyama T, Takaki A, Iwami T, Hadano Y, Mochizuki M, Hiratsuka A, Shimizu A, Matsuzaki M.

J Cardiol. 2011 Mar;57(2):208-14. doi: 10.1016/j.jjcc.2010.11.006. Epub 2010 Dec 23.

21.

Cooperation of NAD(P)H:quinone oxidoreductase 1 and UDP-glucuronosyltransferases reduces menadione cytotoxicity in HEK293 cells.

Nishiyama T, Izawa T, Usami M, Ohnuma T, Ogura K, Hiratsuka A.

Biochem Biophys Res Commun. 2010 Apr 9;394(3):459-63. doi: 10.1016/j.bbrc.2009.12.113. Epub 2009 Dec 24.

PMID:
20035715
22.

Activation of the Nrf2/ARE pathway via S-alkylation of cysteine 151 in the chemopreventive agent-sensor Keap1 protein by falcarindiol, a conjugated diacetylene compound.

Ohnuma T, Nakayama S, Anan E, Nishiyama T, Ogura K, Hiratsuka A.

Toxicol Appl Pharmacol. 2010 Apr 1;244(1):27-36. doi: 10.1016/j.taap.2009.12.012. Epub 2009 Dec 21.

PMID:
20026152
23.

Fully automated two-dimensional electrophoresis system for high-throughput protein analysis.

Hiratsuka A, Yokoyama K.

Methods Mol Biol. 2009;577:155-66. doi: 10.1007/978-1-60761-232-2_12.

PMID:
19718515
24.

Induction of antioxidant and phase 2 drug-metabolizing enzymes by falcarindiol isolated from Notopterygium incisum extract, which activates the Nrf2/ARE pathway, leads to cytoprotection against oxidative and electrophilic stress.

Ohnuma T, Komatsu T, Nakayama S, Nishiyama T, Ogura K, Hiratsuka A.

Arch Biochem Biophys. 2009 Aug 1;488(1):34-41. doi: 10.1016/j.abb.2009.06.006. Epub 2009 Jun 13.

PMID:
19527678
25.

Inhibitory effects of herbal extracts on the activity of human sulfotransferase isoform sulfotransferase 1A3 (SULT1A3).

Nagai M, Fukamachi T, Tsujimoto M, Ogura K, Hiratsuka A, Ohtani H, Hori S, Sawada Y.

Biol Pharm Bull. 2009 Jan;32(1):105-9.

26.

Cardio-ankle vascular index is superior to brachial-ankle pulse wave velocity as an index of arterial stiffness.

Takaki A, Ogawa H, Wakeyama T, Iwami T, Kimura M, Hadano Y, Matsuda S, Miyazaki Y, Hiratsuka A, Matsuzaki M.

Hypertens Res. 2008 Jul;31(7):1347-55. doi: 10.1291/hypres.31.1347.

PMID:
18957805
27.

Amino acid positions 69-132 of UGT1A9 are involved in the C-glucuronidation of phenylbutazone.

Nishiyama T, Fujishima M, Masuda Y, Izawa T, Ohnuma T, Ogura K, Hiratsuka A.

Arch Biochem Biophys. 2008 Oct 1;478(1):75-80. doi: 10.1016/j.abb.2008.06.013. Epub 2008 Jun 24.

PMID:
18602884
28.

Plasma profiling of intact isoflavone metabolites by high-performance liquid chromatography and mass spectrometric identification of flavone glycosides daidzin and genistin in human plasma after administration of kinako.

Hosoda K, Furuta T, Yokokawa A, Ogura K, Hiratsuka A, Ishii K.

Drug Metab Dispos. 2008 Aug;36(8):1485-95. doi: 10.1124/dmd.108.021006. Epub 2008 Apr 28.

29.

UDP-glucuronosyltransferases 1A6 and 1A10 catalyze reduced menadione glucuronidation.

Nishiyama T, Ohnuma T, Inoue Y, Kishi T, Ogura K, Hiratsuka A.

Biochem Biophys Res Commun. 2008 Jun 27;371(2):247-50. doi: 10.1016/j.bbrc.2008.04.040. Epub 2008 Apr 29.

PMID:
18423374
30.

Amperometric biosensor based on glucose dehydrogenase and plasma-polymerized thin films.

Hiratsuka A, Fujisawa K, Muguruma H.

Anal Sci. 2008 Apr;24(4):483-6.

31.

Redox cycling of 9,10-phenanthraquinone to cause oxidative stress is terminated through its monoglucuronide conjugation in human pulmonary epithelial A549 cells.

Taguchi K, Shimada M, Fujii S, Sumi D, Pan X, Yamano S, Nishiyama T, Hiratsuka A, Yamamoto M, Cho AK, Froines JR, Kumagai Y.

Free Radic Biol Med. 2008 Apr 15;44(8):1645-55. doi: 10.1016/j.freeradbiomed.2008.01.024. Epub 2008 Feb 9.

PMID:
18294972
32.

Cardio-ankle vascular index is a new noninvasive parameter of arterial stiffness.

Takaki A, Ogawa H, Wakeyama T, Iwami T, Kimura M, Hadano Y, Matsuda S, Miyazaki Y, Matsuda T, Hiratsuka A, Matsuzaki M.

Circ J. 2007 Nov;71(11):1710-4.

33.

Inhibitory effects of various beverages on human recombinant sulfotransferase isoforms SULT1A1 and SULT1A3.

Nishimuta H, Ohtani H, Tsujimoto M, Ogura K, Hiratsuka A, Sawada Y.

Biopharm Drug Dispos. 2007 Dec;28(9):491-500.

PMID:
17876860
34.

Fully automated two-dimensional electrophoresis system for high-throughput protein analysis.

Hiratsuka A, Kinoshita H, Maruo Y, Takahashi K, Akutsu S, Hayashida C, Sakairi K, Usui K, Shiseki K, Inamochi H, Nakada Y, Yodoya K, Namatame I, Unuma Y, Nakamura M, Ueyama K, Ishii Y, Yano K, Yokoyama K.

Anal Chem. 2007 Aug 1;79(15):5730-9. Epub 2007 Jun 28.

PMID:
17602572
35.

[Usefulness of small group discussion using KJ method regarding early exposure for first-year pharmaceutical science students].

Takayanagi R, Yamada Y, Ozeki T, Yokoyama H, Hiratsuka A, Ohno N, Sasatsu M.

Yakugaku Zasshi. 2006 Nov;126(11):1179-83. Japanese.

36.

A self-contained polymeric 2-DE chip system for rapid and easy analysis.

Usui K, Hiratsuka A, Shiseki K, Maruo Y, Matsushima T, Takahashi K, Unuma Y, Sakairi K, Namatame I, Ogawa Y, Yokoyama K.

Electrophoresis. 2006 Sep;27(18):3635-42.

PMID:
16977685
37.

Identification of human UDP-glucuronosyltransferase isoform(s) responsible for the C-glucuronidation of phenylbutazone.

Nishiyama T, Kobori T, Arai K, Ogura K, Ohnuma T, Ishii K, Hayashi K, Hiratsuka A.

Arch Biochem Biophys. 2006 Oct 1;454(1):72-9. Epub 2006 Aug 7.

PMID:
16949544
38.

Positive association of serum levels of advanced glycation end products with thrombogenic markers in humans.

Enomoto M, Adachi H, Yamagishi S, Takeuchi M, Furuki K, Hino A, Hiratsuka A, Takajo Y, Imaizumi T.

Metabolism. 2006 Jul;55(7):912-7.

PMID:
16784963
39.

Quaternary ammonium-linked glucuronidation of trans-4-hydroxytamoxifen, an active metabolite of tamoxifen, by human liver microsomes and UDP-glucuronosyltransferase 1A4.

Ogura K, Ishikawa Y, Kaku T, Nishiyama T, Ohnuma T, Muro K, Hiratsuka A.

Biochem Pharmacol. 2006 Apr 28;71(9):1358-69. Epub 2006 Feb 14.

PMID:
16480962
40.

CYP3A4 and CYP2D6 inhibitory activities of Indonesian medicinal plants.

Usia T, Iwata H, Hiratsuka A, Watabe T, Kadota S, Tezuka Y.

Phytomedicine. 2006 Jan;13(1-2):67-73. Epub 2005 Jun 29.

PMID:
16360935
41.

Electron transfer mediator micro-biosensor fabrication by organic plasma process.

Hiratsuka A, Kojima K, Muguruma H, Lee KH, Suzuki H, Karube I.

Biosens Bioelectron. 2005 Dec 15;21(6):957-64.

PMID:
16257665
42.

High plasma level of remnant-like particle cholesterol in the metabolic syndrome.

Satoh A, Adachi H, Tsuruta M, Hirai Y, Hiratsuka A, Enomoto M, Furuki K, Hino A, Takeuchi T, Imaizumi T.

Diabetes Care. 2005 Oct;28(10):2514-8.

PMID:
16186289
43.

Inhibitory effects of various beverages on ritodrine sulfation by recombinant human sulfotransferase isoforms SULT1A1 and SULT1A3.

Nishimuta H, Tsujimoto M, Ogura K, Hiratsuka A, Ohtani H, Sawada Y.

Pharm Res. 2005 Aug;22(8):1406-10. Epub 2005 Aug 3.

PMID:
16078151
44.

Dihydropyrimidine dehydrogenase activity in 150 healthy Japanese volunteers and identification of novel mutations.

Ogura K, Ohnuma T, Minamide Y, Mizuno A, Nishiyama T, Nagashima S, Kanamaru M, Hiratsuka A, Watabe T, Uematsu T.

Clin Cancer Res. 2005 Jul 15;11(14):5104-11.

45.

Mechanism-based inactivation of human liver microsomal CYP3A4 by rutaecarpine and limonin from Evodia fruit extract.

Iwata H, Tezuka Y, Kadota S, Hiratsuka A, Watabe T.

Drug Metab Pharmacokinet. 2005 Feb;20(1):34-45.

46.

Strong association between serum hepatocyte growth factor and metabolic syndrome.

Hiratsuka A, Adachi H, Fujiura Y, Yamagishi S, Hirai Y, Enomoto M, Satoh A, Hino A, Furuki K, Imaizumi T.

J Clin Endocrinol Metab. 2005 May;90(5):2927-31. Epub 2005 Feb 15.

PMID:
15713721
47.

Sulfation of environmental estrogens by cytosolic human sulfotransferases.

Nishiyama T, Ogura K, Nakano H, Kaku T, Takahashi E, Ohkubo Y, Sekine K, Hiratsuka A, Kadota S, Watabe T.

Drug Metab Pharmacokinet. 2002;17(3):221-8.

48.

Regioselective monosulfation and disulfation of the phytoestrogens daidzein and genistein by human liver sulfotransferases.

Nakano H, Ogura K, Takahashi E, Harada T, Nishiyama T, Muro K, Hiratsuka A, Kadota S, Watabe T.

Drug Metab Pharmacokinet. 2004 Jun;19(3):216-26.

49.

Identification and characterization of potent CYP3A4 inhibitors in Schisandra fruit extract.

Iwata H, Tezuka Y, Kadota S, Hiratsuka A, Watabe T.

Drug Metab Dispos. 2004 Dec;32(12):1351-8. Epub 2004 Sep 1.

50.

Very long chain N-3 fatty acids intake and carotid atherosclerosis: an epidemiological study evaluated by ultrasonography.

Hino A, Adachi H, Toyomasu K, Yoshida N, Enomoto M, Hiratsuka A, Hirai Y, Satoh A, Imaizumi T.

Atherosclerosis. 2004 Sep;176(1):145-9.

PMID:
15306187

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