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Comprehensive behavioral analysis of indoleamine 2,3-dioxygenase knockout mice.

Hirata N, Hattori S, Shoji H, Funakoshi H, Miyakawa T.

Neuropsychopharmacol Rep. 2018 Sep;38(3):133-144. doi: 10.1002/npr2.12019. Epub 2018 Aug 11.


Factors related to difficult self-expandable metallic stent placement for malignant colonic obstruction: A post-hoc analysis of a multicenter study across Japan.

Kuwai T, Yamaguchi T, Imagawa H, Yoshida S, Isayama H, Matsuzawa T, Yamada T, Saito S, Shimada M, Hirata N, Sasaki T, Koizumi K, Maetani I, Saida Y.

Dig Endosc. 2018 Aug 16. doi: 10.1111/den.13260. [Epub ahead of print]


Lactococcus lactis cholangitis and bacteremia identified by MALDI-TOF mass spectrometry: A case report and review of the literature on Lactococcus lactis infection.

Shimizu A, Hase R, Suzuki D, Toguchi A, Otsuka Y, Hirata N, Hosokawa N.

J Infect Chemother. 2018 Aug 9. pii: S1341-321X(18)30227-7. doi: 10.1016/j.jiac.2018.07.010. [Epub ahead of print]


Dexmedetomidine Does Not Affect Platelet Function Measured With TEG 6S and Platelet Mapping Assay in Whole Blood.

Yoshikawa Y, Takahashi K, Edanaga M, Hirata N, Yamakage M.

J Cardiothorac Vasc Anesth. 2018 Jun 27. pii: S1053-0770(18)30410-5. doi: 10.1053/j.jvca.2018.06.018. [Epub ahead of print] No abstract available.


Self-expandable metallic stenting as a bridge to surgery for malignant colorectal obstruction: pooled analysis of 426 patients from two prospective multicenter series.

Tomita M, Saito S, Makimoto S, Yoshida S, Isayama H, Yamada T, Matsuzawa T, Enomoto T, Kyo R, Kuwai T, Hirata N, Shimada M, Hirakawa T, Koizumi K, Saida Y.

Surg Endosc. 2018 Jul 13. doi: 10.1007/s00464-018-6324-8. [Epub ahead of print]


Tuberculous pneumonia-induced severe ARDS complicated with DIC in a female child: a case of successful treatment.

Ngo DT, Phan PH, Kawachi S, Nakajima N, Hirata N, Ainai A, Phung TTB, Tran DM, Le HT.

BMC Infect Dis. 2018 Jul 3;18(1):294. doi: 10.1186/s12879-018-3215-5.


AKT keeps the beat in CLOCK's circadian rhythm.

Noguchi M, Hirata N, Suizu F.

J Biol Chem. 2018 Jun 8;293(23):9137-9138. doi: 10.1074/jbc.H118.003177.


Functional characterization of lysosomal interaction of Akt with VRK2.

Hirata N, Suizu F, Matsuda-Lennikov M, Tanaka T, Edamura T, Ishigaki S, Donia T, Lithanatudom P, Obuse C, Iwanaga T, Noguchi M.

Oncogene. 2018 Oct;37(40):5367-5386. doi: 10.1038/s41388-018-0330-0. Epub 2018 Jun 5.


Potent Th2 Cytokine Bias of Natural Killer T Cell by CD1d Glycolipid Ligands: Anchoring Effect of Polar Groups in the Lipid Component.

Inuki S, Kashiwabara E, Hirata N, Kishi J, Nabika E, Fujimoto Y.

Angew Chem Int Ed Engl. 2018 Jul 26;57(31):9655-9659. doi: 10.1002/anie.201802983. Epub 2018 Jun 29.


Hemodialysis is a strong risk factor for post-endoscopic sphincterotomy bleeding in patients with choledocholithiasis.

Nakaji S, Hirata N, Matsui H, Shiratori T, Kobayashi M, Yoshimura S, Kanda K, Kawamitsu N, Harasawa H.

Endosc Int Open. 2018 May;6(5):E568-E574. doi: 10.1055/a-0587-4470. Epub 2018 May 8.


Structural Development of Cell-Penetrating Peptides Containing Cationic Proline Derivatives.

Kobayashi H, Misawa T, Oba M, Hirata N, Kanda Y, Tanaka M, Matsuno K, Demizu Y.

Chem Pharm Bull (Tokyo). 2018;66(5):575-580. doi: 10.1248/cpb.c18-00079.


Effect of remifentanil during cardiopulmonary bypass on incidence of acute kidney injury after cardiac surgery.

Sakai W, Yoshikawa Y, Hirata N, Yamakage M.

J Anesth. 2017 Dec;31(6):895-902. doi: 10.1007/s00540-017-2419-y. Epub 2017 Oct 30.


Nitrite administration improves sepsis-induced myocardial and mitochondrial dysfunction by modulating stress signal responses.

Kawaguchi R, Hirata N, Tokinaga Y, Hayashi S, Inoue S, Watanabe N, Yamakage M.

J Anesth. 2017 Dec;31(6):885-894. doi: 10.1007/s00540-017-2417-0. Epub 2017 Oct 23.


Immunoadsorption using Immusorba TR and PH.

Hirano R, Hirata N.

Transfus Apher Sci. 2017 Oct;56(5):661-665. doi: 10.1016/j.transci.2017.08.011. Epub 2017 Aug 30. Review.


Plasma separation using a membrane.

Hirano R, Namazuda K, Suemitsu J, Harashima T, Hirata N.

Transfus Apher Sci. 2017 Oct;56(5):649-653. doi: 10.1016/j.transci.2017.08.008. Epub 2017 Aug 31. Review.


Dexmedetomidine Maintains Its Direct Cardioprotective Effect Against Ischemia/Reperfusion Injury in Hypertensive Hypertrophied Myocardium.

Yoshikawa Y, Hirata N, Kawaguchi R, Tokinaga Y, Yamakage M.

Anesth Analg. 2018 Feb;126(2):443-452. doi: 10.1213/ANE.0000000000002452.


Factors Associated With Psycho-Cognitive Functions in Patients With Persistent Pain After Surgery for Femoral Neck Fracture.

Kitayama A, Hida M, Takami H, Hirata N, Deguchi Y, Miyaguchi K, Nakazono M, Nakagawa R, Fukumoto N, Hamaoka K.

J Clin Med Res. 2017 Sep;9(9):771-775. doi: 10.14740/jocmr3104w. Epub 2017 Jul 27.


Does the weakening of intrinsic foot muscles cause the decrease of medial longitudinal arch height?

Okamura K, Kanai S, Oki S, Tanaka S, Hirata N, Sakamura Y, Idemoto N, Wada H, Otsuka A.

J Phys Ther Sci. 2017 Jun;29(6):1001-1005. doi: 10.1589/jpts.29.1001. Epub 2017 Jun 7.


Gastroduodenal Intussusception with a Gastric Gastrointestinal Stromal Tumor Treated by Endoscopic Submucosal Dissection.

Yamauchi K, Iwamuro M, Ishii E, Narita M, Hirata N, Okada H.

Intern Med. 2017;56(12):1515-1519. doi: 10.2169/internalmedicine.56.8160. Epub 2017 Jun 15.


Macrophage-stimulating activities of newly isolated complex polysaccharides from Parachlorella kessleri strain KNK-A001.

Ueno M, Cho K, Hirata N, Yamashita K, Yamaguchi K, Kim D, Oda T.

Int J Biol Macromol. 2017 Nov;104(Pt A):400-406. doi: 10.1016/j.ijbiomac.2017.06.014. Epub 2017 Jun 6.


Synthesis of Bisdesmosidic Oleanolic Acid Saponins via a Glycosylation-Deprotection Sequence under Continuous Microfluidic/Batch Conditions.

Konishi N, Shirahata T, Yokoyama M, Katsumi T, Ito Y, Hirata N, Nishino T, Makino K, Sato N, Nagai T, Kiyohara H, Yamada H, Kaji E, Kobayashi Y.

J Org Chem. 2017 Jul 7;82(13):6703-6719. doi: 10.1021/acs.joc.7b00841. Epub 2017 Jun 21.


Photoexcited State Confinement in Two-Dimensional Crystalline Anthracene Monolayer at Room Temperature.

Shibuta M, Hirata N, Eguchi T, Nakajima A.

ACS Nano. 2017 Apr 25;11(4):4307-4314. doi: 10.1021/acsnano.7b01506. Epub 2017 Apr 13.


Tobacco nitrosamine NNK increases ALDH-positive cells via ROS-Wnt signaling pathway in A549 human lung cancer cells.

Hirata N, Yamada S, Sekino Y, Kanda Y.

J Toxicol Sci. 2017;42(2):193-204. doi: 10.2131/jts.42.193.


Clinical utility of 0.025-inch guidewire VisiGlide2TM in the endoscopic retrograde cholangiopancreatography-related procedures.

Sakai Y, Tsuyuguchi T, Hirata N, Nakaji S, Shimura K, Nishikawa T, Fujimoto T, Hamano T, Nishino T, Yokosuka O.

World J Gastrointest Endosc. 2017 Feb 16;9(2):77-84. doi: 10.4253/wjge.v9.i2.77.


Syntheses and mucosal adjuvant activity of simplified oleanolic acid saponins possessing cinnamoyl ester.

Shirahata T, Nagai T, Hirata N, Yokoyama M, Katsumi T, Konishi N, Nishino T, Makino K, Yamada H, Kaji E, Kiyohara H, Kobayashi Y.

Bioorg Med Chem. 2017 Mar 15;25(6):1747-1755. doi: 10.1016/j.bmc.2016.09.052. Epub 2016 Sep 22.


EZH2 inhibition suppresses endometrial cancer progression via miR-361/Twist axis.

Ihira K, Dong P, Xiong Y, Watari H, Konno Y, Hanley SJ, Noguchi M, Hirata N, Suizu F, Yamada T, Kudo M, Sakuragi N.

Oncotarget. 2017 Feb 21;8(8):13509-13520. doi: 10.18632/oncotarget.14586.


Remifentanil prevents increases of blood glucose and lactate levels during cardiopulmonary bypass in pediatric cardiac surgery.

Chaki T, Nawa Y, Tamashiro K, Mizuno E, Hirata N, Yamakage M.

Ann Card Anaesth. 2017 Jan-Mar;20(1):33-37. doi: 10.4103/0971-9784.197827.


A Synthetic Hybrid Molecule for the Selective Removal of Human Pluripotent Stem Cells from Cell Mixtures.

Mao D, Ando S, Sato SI, Qin Y, Hirata N, Katsuda Y, Kawase E, Kuo TF, Minami I, Shiba Y, Ueda K, Nakatsuji N, Uesugi M.

Angew Chem Int Ed Engl. 2017 Feb 6;56(7):1765-1770. doi: 10.1002/anie.201610284. Epub 2017 Jan 9.


Short-course antimicrobial treatment for acute cholangitis with Gram-negative bacillary bacteremia.

Uno S, Hase R, Kobayashi M, Shiratori T, Nakaji S, Hirata N, Hosokawa N.

Int J Infect Dis. 2017 Feb;55:81-85. doi: 10.1016/j.ijid.2016.12.018. Epub 2016 Dec 24.


Factors associated with the relapse of cryptogenic and secondary organizing pneumonia.

Onishi Y, Kawamura T, Nakahara Y, Kagami R, Sasaki S, Takahashi S, Kominami R, Hirano K, Hiraoka R, Hirata N.

Respir Investig. 2017 Jan;55(1):10-15. doi: 10.1016/j.resinv.2016.09.001. Epub 2016 Oct 25.


Clinical outcomes of endoscopic ultrasound-guided ethanol injection for hepatocellular carcinoma in the caudate lobe.

Nakaji S, Hirata N, Mikata R, Kobayashi M, Shiratori T, Ogasawara S, Ooka Y, Tsuyuguchi T, Yamaguchi T, Yokosuka O.

Endosc Int Open. 2016 Oct;4(10):E1111-E1115. Epub 2016 Sep 30.


Isolated Polar Amino Acid Residues Modulate Lipid Binding in the Large Hydrophobic Cavity of CD1d.

Inuki S, Aiba T, Hirata N, Ichihara O, Yoshidome D, Kita S, Maenaka K, Fukase K, Fujimoto Y.

ACS Chem Biol. 2016 Nov 18;11(11):3132-3139. Epub 2016 Oct 4.


Phosphorylation-dependent Akt-Inversin interaction at the basal body of primary cilia.

Suizu F, Hirata N, Kimura K, Edamura T, Tanaka T, Ishigaki S, Donia T, Noguchi H, Iwanaga T, Noguchi M.

EMBO J. 2016 Jun 15;35(12):1346-63. doi: 10.15252/embj.201593003. Epub 2016 May 23.


Tributyltin induces mitochondrial fission through Mfn1 degradation in human induced pluripotent stem cells.

Yamada S, Asanagi M, Hirata N, Itagaki H, Sekino Y, Kanda Y.

Toxicol In Vitro. 2016 Aug;34:257-63. doi: 10.1016/j.tiv.2016.04.013. Epub 2016 Apr 29.


Characterization of the room temperature payload prototype for the cryogenic interferometric gravitational wave detector KAGRA.

Peña Arellano FE, Sekiguchi T, Fujii Y, Takahashi R, Barton M, Hirata N, Shoda A, van Heijningen J, Flaminio R, DeSalvo R, Okutumi K, Akutsu T, Aso Y, Ishizaki H, Ohishi N, Yamamoto K, Uchiyama T, Miyakawa O, Kamiizumi M, Takamori A, Majorana E, Agatsuma K, Hennes E, van den Brand J, Bertolini A.

Rev Sci Instrum. 2016 Mar;87(3):034501. doi: 10.1063/1.4942909.


Tributyltin induces G2/M cell cycle arrest via NAD(+)-dependent isocitrate dehydrogenase in human embryonic carcinoma cells.

Asanagi M, Yamada S, Hirata N, Itagaki H, Kotake Y, Sekino Y, Kanda Y.

J Toxicol Sci. 2016 Apr;41(2):207-15. doi: 10.2131/jts.41.207.


Nicotine induces mitochondrial fission through mitofusin degradation in human multipotent embryonic carcinoma cells.

Hirata N, Yamada S, Asanagi M, Sekino Y, Kanda Y.

Biochem Biophys Res Commun. 2016 Feb 5;470(2):300-305. doi: 10.1016/j.bbrc.2016.01.063. Epub 2016 Jan 13.


A prospective multicenter study on self-expandable metallic stents as a bridge to surgery for malignant colorectal obstruction in Japan: efficacy and safety in 312 patients.

Saito S, Yoshida S, Isayama H, Matsuzawa T, Kuwai T, Maetani I, Shimada M, Yamada T, Tomita M, Koizumi K, Hirata N, Kanazawa H, Enomoto T, Sekido H, Saida Y.

Surg Endosc. 2016 Sep;30(9):3976-86. doi: 10.1007/s00464-015-4709-5. Epub 2015 Dec 18.


Endoscopic ultrasonography-guided ethanol injection as a treatment for ruptured hepatocellular carcinoma in the left hepatic lobe.

Nakaji S, Hirata N, Kobayashi M, Shiratori T, Sanagawa M.

Endoscopy. 2015;47 Suppl 1:E558-60. doi: 10.1055/s-0034-1393394. Epub 2015 Nov 26. No abstract available.


Nitrite Reduces Ischemia-Induced Ventricular Arrhythmias by Attenuating Connexin 43 Dephosphorylation in Rats.

Maruyama D, Hirata N, Tokinaga Y, Kawaguchi R, Yamakage M.

Anesth Analg. 2016 Feb;122(2):410-7. doi: 10.1213/ANE.0000000000001063.


Fission Yeast Exo1 and Rqh1-Dna2 Redundantly Contribute to Resection of Uncapped Telomeres.

Nanbu T, Nguyễn LC, Habib AG, Hirata N, Ukimori S, Tanaka D, Masuda K, Takahashi K, Yukawa M, Tsuchiya E, Ueno M.

PLoS One. 2015 Oct 14;10(10):e0140456. doi: 10.1371/journal.pone.0140456. eCollection 2015.


Generation of Brain Microvascular Endothelial-Like Cells from Human Induced Pluripotent Stem Cells by Co-Culture with C6 Glioma Cells.

Minami H, Tashiro K, Okada A, Hirata N, Yamaguchi T, Takayama K, Mizuguchi H, Kawabata K.

PLoS One. 2015 Jun 10;10(6):e0128890. doi: 10.1371/journal.pone.0128890. eCollection 2015.


A Japanese prospective multicenter study of self-expandable metal stent placement for malignant colorectal obstruction: short-term safety and efficacy within 7 days of stent procedure in 513 cases.

Matsuzawa T, Ishida H, Yoshida S, Isayama H, Kuwai T, Maetani I, Shimada M, Yamada T, Saito S, Tomita M, Koizumi K, Hirata N, Sasaki T, Enomoto T, Saida Y.

Gastrointest Endosc. 2015 Oct;82(4):697-707.e1. doi: 10.1016/j.gie.2015.03.1978. Epub 2015 May 12.


Computed tomography enterography as a tool for identifying pancreaticojejunal anastomoses in patients who have undergone Whipple's resection.

Nakaji S, Hirata N, Shiratori T, Kobayashi M.

Endoscopy. 2015;47 Suppl 1 UCTN:E159-60. doi: 10.1055/s-0034-1391421. Epub 2015 Apr 21. No abstract available.


Role and Function of LitR, an Adenosyl B12-Bound Light-Sensitive Regulator of Bacillus megaterium QM B1551, in Regulation of Carotenoid Production.

Takano H, Mise K, Hagiwara K, Hirata N, Watanabe S, Toriyabe M, Shiratori-Takano H, Ueda K.

J Bacteriol. 2015 Jul;197(14):2301-15. doi: 10.1128/JB.02528-14. Epub 2015 Apr 27.


Expression of coxsackievirus and adenovirus receptor separates hematopoietic and cardiac progenitor cells in fetal liver kinase 1-expressing mesoderm.

Tashiro K, Hirata N, Okada A, Yamaguchi T, Takayama K, Mizuguchi H, Kawabata K.

Stem Cells Transl Med. 2015 May;4(5):424-36. doi: 10.5966/sctm.2014-0173. Epub 2015 Mar 11.


Endoscopic ultrasound-guided pancreaticojejunostomy with a forward-viewing echoendoscope as a treatment for stenotic pancreaticojejunal anastomosis.

Nakaji S, Hirata N, Shiratori T, Kobayashi M, Yamauchi K.

Endoscopy. 2015;47 Suppl 1 UCTN:E41-2. doi: 10.1055/s-0034-1391245. Epub 2015 Jan 20. No abstract available.


Movements of the double-lumen endotracheal tube due to lateral position with head rotation and tube fixation: a Thiel-embalmed cadaver study.

Maruyama D, Chaki T, Omote M, Hirata N, Yamauchi M, Yamakage M.

Surg Radiol Anat. 2015 Sep;37(7):841-4. doi: 10.1007/s00276-014-1411-6. Epub 2014 Dec 28.


Directed evolution of cell size in Escherichia coli.

Yoshida M, Tsuru S, Hirata N, Seno S, Matsuda H, Ying BW, Yomo T.

BMC Evol Biol. 2014 Dec 17;14:257. doi: 10.1186/s12862-014-0257-1.

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