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Burden and Long Firing of Premature Atrial Contraction Early After Catheter Ablation Predict Late Recurrence of Atrial Fibrillation.

Inoue H, Tanaka N, Tanaka K, Ninomiya Y, Hirao Y, Oka T, Okada M, Kitagaki R, Takayasu K, Koyama Y, Okamura A, Iwakura K, Fujii K, Sakata Y, Inoue K.

Circ J. 2020 Mar 17. doi: 10.1253/circj.CJ-19-0976. [Epub ahead of print]


Dynamic Changes in pStat3 are Involved in Meiotic Spindle Assembly in Mouse Oocytes.

Haraguchi S, Ikeda M, Akagi S, Hirao Y.

Int J Mol Sci. 2020 Feb 12;21(4). pii: E1220. doi: 10.3390/ijms21041220.


Outcomes After Atrial Fibrillation Ablation in Patients With Premature Atrial Contractions Originating From Non-Pulmonary Veins.

Nakamaru R, Okada M, Tanaka N, Tanaka K, Ninomiya Y, Hirao Y, Oka T, Inoue H, Takayasu K, Koyama Y, Okamura A, Iwakura K, Rakugi H, Sakata Y, Fujii K, Inoue K.

JACC Clin Electrophysiol. 2019 Nov;5(11):1319-1327. doi: 10.1016/j.jacep.2019.08.002. Epub 2019 Oct 2.


Utilization of the Proteome Data Deposited in SRMAtlas for Validating the Existence of the Human Missing Proteins in GPM.

Elguoshy A, Hirao Y, Yamamoto K, Xu B, Kinoshita N, Mitsui T, Yamamoto T.

J Proteome Res. 2019 Dec 6;18(12):4197-4205. doi: 10.1021/acs.jproteome.9b00355. Epub 2019 Oct 24.


Impact of baseline left atrial function on long-term outcome after catheter ablation for paroxysmal atrial fibrillation.

Oka T, Tanaka K, Ninomiya Y, Hirao Y, Tanaka N, Okada M, Inoue H, Takayasu K, Kitagaki R, Koyama Y, Okamura A, Iwakura K, Sakata Y, Fujii K, Inoue K.

J Cardiol. 2020 Apr;75(4):352-359. doi: 10.1016/j.jjcc.2019.08.014. Epub 2019 Sep 12.


Report of the third Asian Prostate Cancer study meeting.

Lojanapiwat B, Lee JY, Gang Z, Kim CS, Fai NC, Hakim L, Umbas R, Ong TA, Lim J, Letran JL, Chiong E, Lee SH, Türkeri L, Murphy DG, Moretti K, Cooperberg M, Carlile R, Hinotsu S, Hirao Y, Kitamura T, Horie S, Onozawa M, Kitagawa Y, Namiki M, Fukagai T, Miyazaki J, Akaza H.

Prostate Int. 2019 Jun;7(2):60-67. doi: 10.1016/j.prnil.2018.06.001. Epub 2018 Jun 14.


Ethylene Inhibits Methyl Jasmonate-Induced Stomatal Closure by Modulating Guard Cell Slow-Type Anion Channel Activity via the OPEN STOMATA 1/SnRK2.6 Kinase-Independent Pathway in Arabidopsis.

Munemasa S, Hirao Y, Tanami K, Mimata Y, Nakamura Y, Murata Y.

Plant Cell Physiol. 2019 Oct 1;60(10):2263-2271. doi: 10.1093/pcp/pcz121.


Amine-tethered phenylboronic acid-enabling ring-opening strategy for carbon chain elongation from double aldol cyclic hemiacetals.

Kanzaki Y, Hirao Y, Mitsunuma H, Kanai M.

Org Biomol Chem. 2019 Jul 21;17(27):6562-6565. doi: 10.1039/c9ob01263j. Epub 2019 Jun 24.


Solvent viscosity-dependent isomerization equilibrium of tetramethoxy-substituted bianthrone.

Hirao Y, Hamamoto Y, Nagamachi N, Kubo T.

Phys Chem Chem Phys. 2019 Jun 21;21(23):12209-12216. doi: 10.1039/c9cp01836k. Epub 2019 Jun 3.


Proteomics Analysis of Urine to Examine Physical Effects of Warm Nano Mist Sauna Bathing.

Hirao Y, Kinoshita N, Xu B, Saito S, Quadery AF, Elguoshy A, Yamamoto K, Yamamoto T.

Healthcare (Basel). 2019 May 19;7(2). pii: E71. doi: 10.3390/healthcare7020071.


Multiple Shifts of the Earliest Retrograde Atrial Activation Site Along the Tricuspid Annulus During the Fast-Slow Form of Atrioventricular Nodal Reentrant Tachycardia by Radiofrequency Modification.

Okada M, Tanaka K, Matsunaga-Lee Y, Ninomiya Y, Hirao Y, Oka T, Tanaka N, Inoue H, Iwakura K, Fujii K, Inoue K.

Int Heart J. 2019 May 30;60(3):761-767. doi: 10.1536/ihj.18-406. Epub 2019 May 17.


Docetaxel-based chemotherapy combined with dexamethasone 1 mg daily oral administration for castration-resistant prostate cancer: Long-term outcomes.

Tanaka N, Nishimura K, Okajima E, Ina K, Ogawa O, Nagata H, Akakura K, Fujimoto K, Gotoh M, Teramukai S, Hirao Y.

Int J Urol. 2019 Aug;26(8):797-803. doi: 10.1111/iju.14009. Epub 2019 May 5.


Molecular Network Analysis of the Urinary Proteome of Alzheimer's Disease Patients.

Watanabe Y, Hirao Y, Kasuga K, Tokutake T, Semizu Y, Kitamura K, Ikeuchi T, Nakamura K, Yamamoto T.

Dement Geriatr Cogn Dis Extra. 2019 Feb 8;9(1):53-65. doi: 10.1159/000496100. eCollection 2019 Jan-Apr.


Comparison of the Safety and Efficacy of Automated Annotation-Guided Radiofrequency Ablation and 2nd-Generation Cryoballoon Ablation in Paroxysmal Atrial Fibrillation.

Tanaka N, Tanaka K, Ninomiya Y, Hirao Y, Oka T, Okada M, Inoue H, Nakamaru R, Takayasu K, Kitagaki R, Koyama Y, Okamura A, Iwakura K, Sakata Y, Fujii K, Inoue K.

Circ J. 2019 Feb 25;83(3):548-555. doi: 10.1253/circj.CJ-18-1035. Epub 2019 Feb 6.


Stable Singlet Biradicals of Rare-Earth-Fused Diporphyrin-Triple-Decker Complexes with Low Energy Gaps and Multi-Redox States.

Lee S, Yamashita KI, Sakata N, Hirao Y, Ogawa K, Ogawa T.

Chemistry. 2019 Mar 1;25(13):3240-3243. doi: 10.1002/chem.201805927. Epub 2019 Feb 6.


Usefulness of Failed Electrical Cardioversion for Early Recurrence After Catheter Ablation for Atrial Fibrillation as a Predictor of Future Recurrence.

Nakamaru R, Tanaka N, Okada M, Tanaka K, Ninomiya Y, Hirao Y, Oka T, Inoue H, Koyama Y, Okamura A, Iwakura K, Rakugi H, Sakata Y, Fujii K, Inoue K.

Am J Cardiol. 2019 Mar 1;123(5):794-800. doi: 10.1016/j.amjcard.2018.11.039. Epub 2018 Dec 4.


Differential Metabolic Responses to Adipose Atrophy Associated with Cancer Cachexia and Caloric Restriction in Rats and the Effect of Rikkunshito in Cancer Cachexia.

Sudo Y, Otsuka H, Miyakawa R, Goto A, Kashiwase Y, Terawaki K, Miyano K, Hirao Y, Taki K, Tagawa R, Kobayashi M, Okita N, Uezono Y, Higami Y.

Int J Mol Sci. 2018 Dec 3;19(12). pii: E3852. doi: 10.3390/ijms19123852.


Transient liver toxicity as a result of the oral administration of 5-aminolevulinic acid for photodynamic diagnosis in patients with bladder cancer.

Miyake M, Nakai Y, Hori S, Morizawa Y, Hirao Y, Fujimoto K.

Int J Urol. 2019 Feb;26(2):315-317. doi: 10.1111/iju.13856. Epub 2018 Nov 18. No abstract available.


Identification of triterpene biosynthetic genes from Momordica charantia using RNA-seq analysis.

Takase S, Kera K, Hirao Y, Hosouchi T, Kotake Y, Nagashima Y, Mannen K, Suzuki H, Kushiro T.

Biosci Biotechnol Biochem. 2019 Feb;83(2):251-261. doi: 10.1080/09168451.2018.1530096. Epub 2018 Oct 13.


Combined androgen blockade achieved better oncological outcome in androgen deprivation therapy for prostate cancer: Analysis of community-based multi-institutional database across Japan using propensity score matching.

Onozawa M, Akaza H, Hinotsu S, Oya M, Ogawa O, Kitamura T, Suzuki K, Naito S, Namiki M, Nishimura K, Hirao Y, Tsukamoto T.

Cancer Med. 2018 Oct;7(10):4893-4902. doi: 10.1002/cam4.1735. Epub 2018 Aug 27.


Donor-Donor'-Acceptor Triads Based on [3.3]Paracyclophane with a 1,4-Dithiafulvene Donor and a Cyanomethylene Acceptor: Synthesis, Structure, and Electrochemical and Photophysical Properties.

Sako K, Hasegawa T, Onda H, Shiotsuka M, Watanabe M, Shinmyozu T, Tojo S, Fujitsuka M, Majima T, Hirao Y, Kubo T, Iwanaga T, Toyota S, Takemura H.

Chemistry. 2018 Aug 6;24(44):11407-11416. doi: 10.1002/chem.201801774. Epub 2018 Jul 6.


Left Atrial Reverse Remodeling After Catheter Ablation of Nonparoxysmal Atrial Fibrillation in Patients With Heart Failure With Reduced Ejection Fraction.

Oka T, Inoue K, Tanaka K, Ninomiya Y, Hirao Y, Tanaka N, Okada M, Inoue H, Nakamaru R, Koyama Y, Okamura A, Iwakura K, Sakata Y, Fujii K.

Am J Cardiol. 2018 Jul 1;122(1):89-96. doi: 10.1016/j.amjcard.2018.03.026. Epub 2018 Mar 29.


Effect of QRS Morphology and Duration on Clinical Outcomes After Cardiac Resynchronization Therapy - Analysis of Japanese Multicenter Registry.

Oka T, Inoue K, Tanaka K, Hirao Y, Isshiki T, Kimura T, Nobuyoshi M, Shizuta S, Arita T, Fujii S, Iwakura K, Fujii K, Ando K.

Circ J. 2018 Jun 25;82(7):1813-1821. doi: 10.1253/circj.CJ-17-1383. Epub 2018 Apr 7.


Structure of a [NiFe] hydrogenase maturation protease HycI provides insights into its substrate selectivity.

Kwon S, Nishitani Y, Hirao Y, Kanai T, Atomi H, Miki K.

Biochem Biophys Res Commun. 2018 Apr 15;498(4):782-788. doi: 10.1016/j.bbrc.2018.03.058. Epub 2018 Mar 15.


Macromolecular crowded conditions strengthen contacts between mouse oocytes and companion granulosa cells during in vitro growth.

Mizumachi S, Aritomi T, Sasaki K, Matsubara K, Hirao Y.

J Reprod Dev. 2018 Apr 13;64(2):153-160. doi: 10.1262/jrd.2017-162. Epub 2018 Feb 16. Erratum in: J Reprod Dev. 2018;64(3):e1.


Polarity-Dependent Isomerization of an Unsymmetrical Overcrowded Ethylene Promoted by Zwitterionic Contribution in the Twisted Isomer.

Hirao Y, Nagamachi N, Hosoi K, Kubo T.

Chem Asian J. 2018 Mar 2;13(5):510-514. doi: 10.1002/asia.201701805. Epub 2018 Feb 9.


Proteome Profiling of Diabetic Mellitus Patient Urine for Discovery of Biomarkers by Comprehensive MS-Based Proteomics.

Hirao Y, Saito S, Fujinaka H, Miyazaki S, Xu B, Quadery AF, Elguoshy A, Yamamoto K, Yamamoto T.

Proteomes. 2018 Feb 6;6(1). pii: E9. doi: 10.3390/proteomes6010009.


Efficacy and Safety of Figure-of-Eight Suture for Hemostasis After Radiofrequency Catheter Ablation for Atrial Fibrillation.

Okada M, Inoue K, Tanaka K, Ninomiya Y, Hirao Y, Oka T, Tanaka N, Inoue H, Nakamaru R, Koyama Y, Okamura A, Iwakura K, Sakata Y, Fujii K.

Circ J. 2018 Mar 23;82(4):956-964. doi: 10.1253/circj.CJ-17-1213. Epub 2018 Jan 26.


A Highly Sensitive FRET Biosensor for AMPK Exhibits Heterogeneous AMPK Responses among Cells and Organs.

Konagaya Y, Terai K, Hirao Y, Takakura K, Imajo M, Kamioka Y, Sasaoka N, Kakizuka A, Sumiyama K, Asano T, Matsuda M.

Cell Rep. 2017 Nov 28;21(9):2628-2638. doi: 10.1016/j.celrep.2017.10.113.


The role of plasma lipoprotein lipase, hepatic lipase and GPIHBP1 in the metabolism of remnant lipoproteins and small dense LDL in patients with coronary artery disease.

Muraba Y, Koga T, Shimomura Y, Ito Y, Hirao Y, Kobayashi J, Kimura T, Nakajima K, Murakami M.

Clin Chim Acta. 2018 Jan;476:146-153. doi: 10.1016/j.cca.2017.11.021. Epub 2017 Nov 22.


Proteomic Analysis of Rice Golgi Membranes Isolated by Floating Through Discontinuous Sucrose Density Gradient.

Oikawa K, Inomata T, Hirao Y, Yamamoto T, Baslam M, Kaneko K, Mitsui T.

Methods Mol Biol. 2018;1696:91-105. doi: 10.1007/978-1-4939-7411-5_6.


Identification and Validation of Human Missing Proteins and Peptides in Public Proteome Databases: Data Mining Strategy.

Elguoshy A, Hirao Y, Xu B, Saito S, Quadery AF, Yamamoto K, Mitsui T, Yamamoto T; Chromosome X Project Team of JProS.

J Proteome Res. 2017 Dec 1;16(12):4403-4414. doi: 10.1021/acs.jproteome.7b00423. Epub 2017 Oct 31.


Glycobiomarker, Fucosylated Short-Form Secretogranin III Levels Are Increased in Serum of Patients with Small Cell Lung Carcinoma.

Togayachi A, Iwaki J, Kaji H, Matsuzaki H, Kuno A, Hirao Y, Nomura M, Noguchi M, Ikehara Y, Narimatsu H.

J Proteome Res. 2017 Dec 1;16(12):4495-4505. doi: 10.1021/acs.jproteome.7b00484. Epub 2017 Oct 12.


A mimetic of the mSin3-binding helix of NRSF/REST ameliorates abnormal pain behavior in chronic pain models.

Ueda H, Kurita JI, Neyama H, Hirao Y, Kouji H, Mishina T, Kasai M, Nakano H, Yoshimori A, Nishimura Y.

Bioorg Med Chem Lett. 2017 Oct 15;27(20):4705-4709. doi: 10.1016/j.bmcl.2017.09.006. Epub 2017 Sep 7.


Report of the Second Asian Prostate Cancer (A-CaP) Study Meeting.

Kim CS, Lee JY, Chung BH, Kim WJ, Fai NC, Hakim L, Umbas R, Ong TA, Lim J, Letran JL, Chiong E, Wu TL, Lojanapiwat B, Türkeri L, Murphy DG, Gardiner RA, Moretti K, Cooperberg M, Carroll P, Mun SK, Hinotsu S, Hirao Y, Ozono S, Horie S, Onozawa M, Kitagawa Y, Kitamura T, Namiki M, Akaza H.

Prostate Int. 2017 Sep;5(3):95-103. doi: 10.1016/j.prnil.2017.03.006. Epub 2017 Mar 29.


Development of fertile mouse oocytes from mitotic germ cells in vitro.

Morohaku K, Hirao Y, Obata Y.

Nat Protoc. 2017 Sep;12(9):1817-1829. doi: 10.1038/nprot.2017.069. Epub 2017 Aug 10.


Reconstitution of mouse oogenesis in a dish from pluripotent stem cells.

Hayashi K, Hikabe O, Obata Y, Hirao Y.

Nat Protoc. 2017 Sep;12(9):1733-1744. doi: 10.1038/nprot.2017.070. Epub 2017 Aug 10.


Elucidation of Intramolecular Through-Space Electronic Communication in a Propeller-Shaped Molecule.

Kodama T, Hirao Y, Nishiuchi T, Kubo T.

Chempluschem. 2017 Jul;82(7):1006-1009. doi: 10.1002/cplu.201700045. Epub 2017 Apr 26.


Different inverse association of large high-density lipoprotein subclasses with exacerbation of insulin resistance and incidence of type 2 diabetes: The Nagahama study.

Tabara Y, Arai H, Hirao Y, Takahashi Y, Setoh K, Kawaguchi T, Kosugi S, Ito Y, Nakayama T, Matsuda F; Nagahama study group.

Diabetes Res Clin Pract. 2017 May;127:123-131. doi: 10.1016/j.diabres.2017.03.018. Epub 2017 Mar 21.


Differentiation of Mouse Primordial Germ Cells into Functional Oocytes In Vitro.

Morohaku K, Hirao Y, Obata Y.

Ann Biomed Eng. 2017 Jul;45(7):1608-1619. doi: 10.1007/s10439-017-1815-7. Epub 2017 Feb 27. Review.


The efficacy and safety of docetaxel-based chemotherapy combined with dexamethasone 1 mg daily oral administration: JMTO Pca 10-01 phase II trial.

Tanaka N, Nishimura K, Okajima E, Ina K, Ogawa O, Nagata H, Akakura K, Fujimoto K, Gotoh M, Teramukai S, Hirao Y.

Jpn J Clin Oncol. 2017 Mar 1;47(3):247-251. doi: 10.1093/jjco/hyw193.


The causal effects of alcohol on lipoprotein subfraction and triglyceride levels using a Mendelian randomization analysis: The Nagahama study.

Tabara Y, Arai H, Hirao Y, Takahashi Y, Setoh K, Kawaguchi T, Kosugi S, Ito Y, Nakayama T, Matsuda F; Nagahama study group.

Atherosclerosis. 2017 Feb;257:22-28. doi: 10.1016/j.atherosclerosis.2016.12.008. Epub 2016 Dec 22.


Synchronization of In Vitro Maturation in Porcine Oocytes.

Somfai T, Hirao Y.

Methods Mol Biol. 2017;1524:255-264.


Reconstitution in vitro of the entire cycle of the mouse female germ line.

Hikabe O, Hamazaki N, Nagamatsu G, Obata Y, Hirao Y, Hamada N, Shimamoto S, Imamura T, Nakashima K, Saitou M, Hayashi K.

Nature. 2016 Nov 10;539(7628):299-303. doi: 10.1038/nature20104. Epub 2016 Oct 17.


Radical Cation of an Oligoarylamine Having a Nitroxide Radical Substituent: A Coexistent Molecular System of Localized and Delocalized Spins.

Ito A, Kurata R, Noma Y, Hirao Y, Tanaka K.

J Org Chem. 2016 Nov 18;81(22):11416-11420. Epub 2016 Nov 1.


Why are they missing? : Bioinformatics characterization of missing human proteins.

Elguoshy A, Magdeldin S, Xu B, Hirao Y, Zhang Y, Kinoshita N, Takisawa Y, Nameta M, Yamamoto K, El-Refy A, El-Fiky F, Yamamoto T.

J Proteomics. 2016 Oct 21;149:7-14. doi: 10.1016/j.jprot.2016.08.005. Epub 2016 Aug 13.


Asia prostate cancer study (A-CaP Study) launch symposium.

Akaza H, Hirao Y, Kim CS, Oya M, Ozono S, Ye D, Cooperberg M, Hinotsu S, Lee JY, Zhu G, Namiki M, Horie S, Chung BH, Chen CH, Fai NC, Hakim L, Chiong E, Letran J, Umbas R, Suzuki K, Nishimura K, Ong TA, Lojanapiwat B, Wu TL, Kim WJ, Murphy D, Ogawa O, Carroll P, Naito S, Tsukamoto T.

Prostate Int. 2016 Sep;4(3):88-96. doi: 10.1016/j.prnil.2016.03.001. Epub 2016 Mar 10.


Extensive ossification of the paraspinal ligaments in a patient with vitamin D-resistant rickets: Case report with literature review.

Hirao Y, Chikuda H, Oshima Y, Matsubayashi Y, Tanaka S.

Int J Surg Case Rep. 2016;27:125-128. doi: 10.1016/j.ijscr.2016.08.038. Epub 2016 Aug 28.

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