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Items: 16

1.

PPARα-targeted mitochondrial bioenergetics mediate repair of intestinal barriers at the host-microbe intersection during SIV infection.

Crakes KR, Santos Rocha C, Grishina I, Hirao LA, Napoli E, Gaulke CA, Fenton A, Datta S, Arredondo J, Marco ML, Sankaran-Walters S, Cortopassi G, Giulivi C, Dandekar S.

Proc Natl Acad Sci U S A. 2019 Dec 3;116(49):24819-24829. doi: 10.1073/pnas.1908977116. Epub 2019 Nov 18.

2.

Subclinical Cytomegalovirus Infection Is Associated with Altered Host Immunity, Gut Microbiota, and Vaccine Responses.

Santos Rocha C, Hirao LA, Weber MG, Méndez-Lagares G, Chang WLW, Jiang G, Deere JD, Sparger EE, Roberts J, Barry PA, Hartigan-O'Connor DJ, Dandekar S.

J Virol. 2018 Jun 13;92(13). pii: e00167-18. doi: 10.1128/JVI.00167-18. Print 2018 Jul 1.

3.

HIV Exploits Antiviral Host Innate GCN2-ATF4 Signaling for Establishing Viral Replication Early in Infection.

Jiang G, Santos Rocha C, Hirao LA, Mendes EA, Tang Y, Thompson GR 3rd, Wong JK, Dandekar S.

mBio. 2017 May 2;8(3). pii: e01518-16. doi: 10.1128/mBio.01518-16.

4.
5.

Loss of Multicellular Behavior in Epidemic African Nontyphoidal Salmonella enterica Serovar Typhimurium ST313 Strain D23580.

Singletary LA, Karlinsey JE, Libby SJ, Mooney JP, Lokken KL, Tsolis RM, Byndloss MX, Hirao LA, Gaulke CA, Crawford RW, Dandekar S, Kingsley RA, Msefula CL, Heyderman RS, Fang FC.

mBio. 2016 Mar 1;7(2):e02265. doi: 10.1128/mBio.02265-15.

6.

Gut immune dysfunction through impaired innate pattern recognition receptor expression and gut microbiota dysbiosis in chronic SIV infection.

Glavan TW, Gaulke CA, Santos Rocha C, Sankaran-Walters S, Hirao LA, Raffatellu M, Jiang G, Bäumler AJ, Goulart LR, Dandekar S.

Mucosal Immunol. 2016 May;9(3):677-88. doi: 10.1038/mi.2015.92. Epub 2015 Sep 16.

7.

SIV-infection-driven changes of pattern recognition receptor expression in mesenteric lymph nodes and gut microbiota dysbiosis.

Glavan TW, Gaulke CA, Hirao LA, Sankaran-Walters S, Dandekar S.

J Med Primatol. 2015 Oct;44(5):241-52. doi: 10.1111/jmp.12187. Epub 2015 Aug 14.

PMID:
26275157
8.

Early mucosal sensing of SIV infection by paneth cells induces IL-1β production and initiates gut epithelial disruption.

Hirao LA, Grishina I, Bourry O, Hu WK, Somrit M, Sankaran-Walters S, Gaulke CA, Fenton AN, Li JA, Crawford RW, Chuang F, Tarara R, Marco ML, Bäumler AJ, Cheng H, Dandekar S.

PLoS Pathog. 2014 Aug 28;10(8):e1004311. doi: 10.1371/journal.ppat.1004311. eCollection 2014 Aug.

9.

Chronic HIV infection enhances the responsiveness of antigen presenting cells to commensal Lactobacillus.

Nagy LH, Grishina I, Macal M, Hirao LA, Hu WK, Sankaran-Walters S, Gaulke CA, Pollard R, Brown J, Suni M, Baumler AJ, Ghanekar S, Marco ML, Dandekar S.

PLoS One. 2013 Aug 30;8(8):e72789. doi: 10.1371/journal.pone.0072789. eCollection 2013.

10.

Immune modulation through 4-1BB enhances SIV vaccine protection in non-human primates against SIVmac251 challenge.

Hirao LA, Hokey DA, Morrow MP, Jure-Kunkel MN, Weiner DB.

PLoS One. 2011;6(9):e24250. doi: 10.1371/journal.pone.0024250. Epub 2011 Sep 15.

11.

Th17 cells and regulatory T cells in elite control over HIV and SIV.

Hartigan-O'Connor DJ, Hirao LA, McCune JM, Dandekar S.

Curr Opin HIV AIDS. 2011 May;6(3):221-7. doi: 10.1097/COH.0b013e32834577b3. Review.

12.

Multivalent smallpox DNA vaccine delivered by intradermal electroporation drives protective immunity in nonhuman primates against lethal monkeypox challenge.

Hirao LA, Draghia-Akli R, Prigge JT, Yang M, Satishchandran A, Wu L, Hammarlund E, Khan AS, Babas T, Rhodes L, Silvera P, Slifka M, Sardesai NY, Weiner DB.

J Infect Dis. 2011 Jan 1;203(1):95-102. doi: 10.1093/infdis/jiq017.

13.

Comparative analysis of immune responses induced by vaccination with SIV antigens by recombinant Ad5 vector or plasmid DNA in rhesus macaques.

Hirao LA, Wu L, Satishchandran A, Khan AS, Draghia-Akli R, Finnefrock AC, Bett AJ, Betts MR, Casimiro DR, Sardesai NY, Kim JJ, Shiver JW, Weiner DB.

Mol Ther. 2010 Aug;18(8):1568-76. doi: 10.1038/mt.2010.112. Epub 2010 Jun 15.

14.

CLTA-4 blockade in vivo promotes the generation of short-lived effector CD8 T cells and a more persistent central memory CD4 T cell response.

Hokey DA, Yan J, Hirao LA, Dai A, Boyer JD, Jure-Kunkel MN, Weiner DB.

J Med Primatol. 2008 Dec;37 Suppl 2:62-8. doi: 10.1111/j.1600-0684.2008.00324.x.

PMID:
19187432
15.

Combined effects of IL-12 and electroporation enhances the potency of DNA vaccination in macaques.

Hirao LA, Wu L, Khan AS, Hokey DA, Yan J, Dai A, Betts MR, Draghia-Akli R, Weiner DB.

Vaccine. 2008 Jun 13;26(25):3112-20. doi: 10.1016/j.vaccine.2008.02.036. Epub 2008 Mar 11.

16.

Intradermal/subcutaneous immunization by electroporation improves plasmid vaccine delivery and potency in pigs and rhesus macaques.

Hirao LA, Wu L, Khan AS, Satishchandran A, Draghia-Akli R, Weiner DB.

Vaccine. 2008 Jan 17;26(3):440-8. Epub 2007 Nov 8.

PMID:
18082294

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