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Items: 1 to 50 of 1960

1.

Nitric oxide plays a critical role in methotrexate-induced hyperplasia of enterochromaffin cells containing 5-hydroxytryptamine in rat small intestine.

Takano Y, Hirano M, Machida T, Obara Y, Hamaue N, Fujita K, Taniguchi M, Endo T, Shiga S, Machida M, Iizuka K, Hirafuji M.

J Pharmacol Sci. 2019 Sep 10. pii: S1347-8613(19)35703-2. doi: 10.1016/j.jphs.2019.09.001. [Epub ahead of print]

2.

Growth differentiation factor-15 as a biomarker of strength and recovery in survivors of acute respiratory failure.

Rosenberg BJ, Hirano M, Quinzii CM, Colantuoni E, Needham DM, Lederer DJ, Baldwin MR.

Thorax. 2019 Sep 18. pii: thoraxjnl-2019-213621. doi: 10.1136/thoraxjnl-2019-213621. [Epub ahead of print]

PMID:
31534031
3.

Redefining the Etiologic Landscape of Cerebellar Malformations.

Aldinger KA, Timms AE, Thomson Z, Mirzaa GM, Bennett JT, Rosenberg AB, Roco CM, Hirano M, Abidi F, Haldipur P, Cheng CV, Collins S, Park K, Zeiger J, Overmann LM, Alkuraya FS, Biesecker LG, Braddock SR, Cathey S, Cho MT, Chung BHY, Everman DB, Zarate YA, Jones JR, Schwartz CE, Goldstein A, Hopkin RJ, Krantz ID, Ladda RL, Leppig KA, McGillivray BC, Sell S, Wusik K, Gleeson JG, Nickerson DA, Bamshad MJ, Gerrelli D, Lisgo SN, Seelig G, Ishak GE, Barkovich AJ, Curry CJ, Glass IA, Millen KJ, Doherty D, Dobyns WB.

Am J Hum Genet. 2019 Sep 5;105(3):606-615. doi: 10.1016/j.ajhg.2019.07.019. Epub 2019 Aug 29.

PMID:
31474318
4.

Next Generation Sequencing-Based Transcriptome Predicts Bevacizumab Efficacy in Combination with Temozolomide in Glioblastoma.

Adilijiang A, Hirano M, Okuno Y, Aoki K, Ohka F, Maeda S, Tanahashi K, Motomura K, Shimizu H, Yamaguchi J, Wakabayashi T, Natsume A.

Molecules. 2019 Aug 22;24(17). pii: E3046. doi: 10.3390/molecules24173046.

5.

Catalytic cross-dimerisation giving reactive borylated polyenes toward cross-coupling.

Hirano M, Kuramochi A, Shimada K, Komine N, Kiyota S, Westcott SA.

Chem Commun (Camb). 2019 Aug 29;55(71):10527-10530. doi: 10.1039/c9cc05930j.

PMID:
31418006
6.

Advances in primary mitochondrial myopathies.

de Barcelos IP, Emmanuele V, Hirano M.

Curr Opin Neurol. 2019 Oct;32(5):715-721. doi: 10.1097/WCO.0000000000000743.

PMID:
31408013
7.

Activity of Adenylyl Cyclase Type 6 Is Suppressed by Direct Binding of the Cytoskeletal Protein 4.1G.

Saito M, Cui L, Hirano M, Li G, Yanagisawa T, Sato T, Sukegawa J.

Mol Pharmacol. 2019 Oct;96(4):441-451. doi: 10.1124/mol.119.116426. Epub 2019 Aug 5.

PMID:
31383768
8.

Bioavailability and cytosolic kinases modulate response to deoxynucleoside therapy in TK2 deficiency.

Lopez-Gomez C, Hewan H, Sierra C, Akman HO, Sanchez-Quintero MJ, Juanola-Falgarona M, Tadesse S, Tanji K, Konofagou EE, Hirano M.

EBioMedicine. 2019 Aug;46:356-367. doi: 10.1016/j.ebiom.2019.07.037. Epub 2019 Aug 2.

9.

Predominant surface property of an anodized titanium that enhances the cell response.

Ohtsu N, Kuji T, Hirano M, Yamasaki K.

Biointerphases. 2019 Jul 29;14(4):041002. doi: 10.1116/1.5108542.

PMID:
31357867
10.

Is Additional Surgery Always Sufficient for Preventing Recurrence After Endoscopic Submucosal Dissection with Curability C-2 for Early Gastric Cancer?

Hatta W, Gotoda T, Oyama T, Kawata N, Takahashi A, Oka S, Hoteya S, Nakagawa M, Hirano M, Esaki M, Matsuda M, Ohnita K, Shimoda R, Yoshida M, Dohi O, Takada J, Tanaka K, Yamada S, Tsuji T, Ito H, Aoyagi H, Nakamura T, Nakaya N, Shimosegawa T, Masamune A.

Ann Surg Oncol. 2019 Oct;26(11):3636-3643. doi: 10.1245/s10434-019-07579-2. Epub 2019 Jul 24.

PMID:
31342376
11.

Specialized Somatosensory-Motor Integration Functions in Musicians.

Hirano M, Kimoto Y, Furuya S.

Cereb Cortex. 2019 Jul 25. pii: bhz154. doi: 10.1093/cercor/bhz154. [Epub ahead of print]

PMID:
31342056
12.

Spontaneous Tumor Regression of Intracranial Solitary Fibrous Tumor Originating From the Medulla Oblongata: A Case Report and Literature Review.

Yamaguchi J, Motomura K, Ohka F, Aoki K, Tanahashi K, Hirano M, Nishikawa T, Shimizu H, Wakabayashi T, Natsume A.

World Neurosurg. 2019 Oct;130:400-404. doi: 10.1016/j.wneu.2019.07.052. Epub 2019 Jul 18.

PMID:
31326640
13.

Effects of the rotigotine transdermal patch versus oral levodopa on swallowing in patients with Parkinson's disease.

Hirano M, Isono C, Fukuda K, Ueno S, Nakamura Y, Kusunoki S.

J Neurol Sci. 2019 Sep 15;404:5-10. doi: 10.1016/j.jns.2019.07.003. Epub 2019 Jul 9.

PMID:
31323520
14.

Rational design of novel amphipathic antimicrobial peptides focused on the distribution of cationic amino acid residues.

Misawa T, Goto C, Shibata N, Hirano M, Kikuchi Y, Naito M, Demizu Y.

Medchemcomm. 2019 Apr 4;10(6):896-900. doi: 10.1039/c9md00166b. eCollection 2019 Jun 1.

PMID:
31303986
15.

Pathological Findings in Male Patients With Anti-N-methyl-d-Aspartate Receptor Encephalitis.

Hirano M, Itoh T, Fujimura H, Inoue K, Samukawa M, Nose K, Sakamoto H, Maekura S, Ueno S, Satou T, Nishioka T, Kusunoki S, Nakamura Y.

J Neuropathol Exp Neurol. 2019 May 31. pii: nlz052. doi: 10.1093/jnen/nlz052. [Epub ahead of print]

PMID:
31282957
16.

Clinicopathological differences between the motor onset and psychiatric onset of Huntington's disease, focusing on the nucleus accumbens.

Hirano M, Iritani S, Fujishiro H, Torii Y, Habuchi C, Sekiguchi H, Yoshida M, Ozaki N.

Neuropathology. 2019 Jul 2. doi: 10.1111/neup.12578. [Epub ahead of print]

PMID:
31264738
17.

Synthesis and Pharmacological Evaluation of 3-[(4-Oxo-4H-pyrido[3,2-e][1,3]thiazin-2-yl)(phenyl)amino]propanenitrile Derivatives as Orally Active AMPA Receptor Antagonists.

Inami H, Shishikura JI, Yasunaga T, Hirano M, Kimura T, Yamashita H, Ohno K, Sakamoto S.

Chem Pharm Bull (Tokyo). 2019;67(7):699-706. doi: 10.1248/cpb.c18-00977.

18.

In vitro assessment of effects of persistent organic pollutants on the transactivation of estrogen receptor α and β (ERα and ERβ) from the Baikal seal (Pusa sibirica).

Yoshinouchi Y, Shimizu S, Lee JS, Hirano M, Suzuki KT, Kim EY, Iwata H.

Ecotoxicol Environ Saf. 2019 Oct 15;181:463-471. doi: 10.1016/j.ecoenv.2019.06.033. Epub 2019 Jun 19.

PMID:
31228822
19.

Different characteristics of postoperative atrial tachyarrhythmias between congenital and non-congenital heart disease.

Kondo M, Fukuda K, Wakayama Y, Nakano M, Hasebe Y, Satake H, Segawa M, Hirano M, Shimokawa H.

J Interv Card Electrophysiol. 2019 Jun 13. doi: 10.1007/s10840-019-00575-2. [Epub ahead of print]

PMID:
31197584
20.

Aberrant Transcriptional Regulation of Super-enhancers by RET Finger Protein-histone Deacetylase 1 Complex in Glioblastoma: Chemoresistance to Temozolomide.

Natsume A, Hirano M, Ranjit M, Aoki K, Wakabayashi T.

Neurol Med Chir (Tokyo). 2019 Aug 15;59(8):293-298. doi: 10.2176/nmc.ra.2019-0049. Epub 2019 Jun 7.

21.

Human aging DNA methylation signatures are conserved but accelerated in cultured fibroblasts.

Sturm G, Cardenas A, Bind MA, Horvath S, Wang S, Wang Y, Hägg S, Hirano M, Picard M.

Epigenetics. 2019 Oct;14(10):961-976. doi: 10.1080/15592294.2019.1626651. Epub 2019 Jun 12.

PMID:
31156022
22.

EN FACE IMAGE-BASED ANALYSIS OF RETINAL TRACTION CAUSED BY EPIRETINAL MEMBRANE AND ITS RELATIONSHIP WITH VISUAL FUNCTIONS.

Hirano M, Morizane Y, Kanzaki Y, Kimura S, Hosokawa M, Shiode Y, Doi S, Toshima S, Takahashi K, Hosogi M, Fujiwara A, Takasu I, Shiraga F.

Retina. 2019 May 23. doi: 10.1097/IAE.0000000000002569. [Epub ahead of print]

PMID:
31136461
23.

Involvement of different receptor subtypes in prostaglandin E2-induced contraction and relaxation in the lower esophageal sphincter and esophageal body.

Bai X, Ihara E, Otsuka Y, Tsuruta S, Hirano K, Tanaka Y, Ogino H, Hirano M, Chinen T, Akiho H, Nakamura K, Oda Y, Ogawa Y.

Eur J Pharmacol. 2019 Aug 15;857:172405. doi: 10.1016/j.ejphar.2019.172405. Epub 2019 May 22.

PMID:
31128092
24.

Deoxynucleoside Therapy for Thymidine Kinase 2-Deficient Myopathy.

Domínguez-González C, Madruga-Garrido M, Mavillard F, Garone C, Aguirre-Rodríguez FJ, Donati MA, Kleinsteuber K, Martí I, Martín-Hernández E, Morealejo-Aycinena JP, Munell F, Nascimento A, Kalko SG, Sardina MD, Álvarez Del Vayo C, Serrano O, Long Y, Tu Y, Levin B, Thompson JLP, Engelstad K, Uddin J, Torres-Torronteras J, Jimenez-Mallebrera C, Martí R, Paradas C, Hirano M.

Ann Neurol. 2019 Aug;86(2):293-303. doi: 10.1002/ana.25506. Epub 2019 Jun 17.

PMID:
31125140
25.

Neurocognitive and functional outcomes in patients with diffuse frontal lower-grade gliomas undergoing intraoperative awake brain mapping.

Motomura K, Chalise L, Ohka F, Aoki K, Tanahashi K, Hirano M, Nishikawa T, Yamaguchi J, Shimizu H, Wakabayashi T, Natsume A.

J Neurosurg. 2019 May 17:1-9. doi: 10.3171/2019.3.JNS19211. [Epub ahead of print]

PMID:
31100731
26.

Age Affects Clinical Management after Noncurative Endoscopic Submucosal Dissection for Early Gastric Cancer.

Esaki M, Hatta W, Shimosegawa T, Oyama T, Kawata N, Takahashi A, Oka S, Hoteya S, Nakagawa M, Hirano M, Matsuda M, Ohnita K, Shimoda R, Yoshida M, Dohi O, Takada J, Tanaka K, Yamada S, Tsuji T, Ito H, Aoyagi H, Gotoda T.

Dig Dis. 2019 May 16:1-11. doi: 10.1159/000499538. [Epub ahead of print]

PMID:
31096243
27.

Mutant-Selective Irreversible EGFR Inhibitor, Naquotinib, Inhibits Tumor Growth in NSCLC Models with EGFR-Activating Mutations, T790M Mutation, and AXL Overexpression.

Tanaka H, Sakagami H, Kaneko N, Konagai S, Yamamoto H, Matsuya T, Yuri M, Yamanaka Y, Mori M, Takeuchi M, Koshio H, Hirano M, Kuromitsu S.

Mol Cancer Ther. 2019 Aug;18(8):1366-1373. doi: 10.1158/1535-7163.MCT-18-0976. Epub 2019 May 15.

PMID:
31092564
28.

The clinical spectrum of the congenital myasthenic syndrome resulting from COL13A1 mutations.

Rodríguez Cruz PM, Cossins J, Estephan EP, Munell F, Selby K, Hirano M, Maroofin R, Mehrjardi MYV, Chow G, Carr A, Manzur A, Robb S, Munot P, Wei Liu W, Banka S, Fraser H, De Goede C, Zanoteli E, Conti Reed U, Sage A, Gratacos M, Macaya A, Dusl M, Senderek J, Töpf A, Hofer M, Knight R, Ramdas S, Jayawant S, Lochmüller H, Palace J, Beeson D.

Brain. 2019 Jun 1;142(6):1547-1560. doi: 10.1093/brain/awz107.

29.

Late-onset thymidine kinase 2 deficiency: a review of 18 cases.

Domínguez-González C, Hernández-Laín A, Rivas E, Hernández-Voth A, Sayas Catalán J, Fernández-Torrón R, Fuiza-Luces C, García García J, Morís G, Olivé M, Miralles F, Díaz-Manera J, Caballero C, Méndez-Ferrer B, Martí R, García Arumi E, Badosa MC, Esteban J, Jimenez-Mallebrera C, Encinar AB, Arenas J, Hirano M, Martin MÁ, Paradas C.

Orphanet J Rare Dis. 2019 May 6;14(1):100. doi: 10.1186/s13023-019-1071-z.

30.

A case of pancreatic pseudocysts accompanied by infection, pseudoaneurysm ruptures, and pseudocystocolonic fistulae.

Sato K, Takahashi K, Aruga Y, Yamazaki F, Kumaki D, Yamakawa M, Hirano M, Funakoshi K, Terai S.

Clin J Gastroenterol. 2019 Apr 23. doi: 10.1007/s12328-019-00986-8. [Epub ahead of print]

PMID:
31016682
31.

A case of functioning gonadotroph adenoma in a reproductive aged woman.

Hirano M, Wada-Hiraike O, Miyamamoto Y, Yamada S, Fujii T, Osuga Y.

Endocr J. 2019 Jul 28;66(7):653-656. doi: 10.1507/endocrj.EJ19-0066. Epub 2019 Apr 19.

32.

HDAC Inhibitors Exert Anti-Myeloma Effects through Multiple Modes of Action.

Imai Y, Hirano M, Kobayashi M, Futami M, Tojo A.

Cancers (Basel). 2019 Apr 4;11(4). pii: E475. doi: 10.3390/cancers11040475. Review.

33.

Mothers' challenges with the parental control of 3-year-old children in Japan: A qualitative study.

Onishi R, Saeki K, Hirano M.

Child Care Health Dev. 2019 Jul;45(4):531-539. doi: 10.1111/cch.12666. Epub 2019 May 10.

PMID:
30983020
34.

A Case of Thoracic Endovascular Aortic Repair Using Carotid Access with Axillary-Carotid Bypass for Descending Aortic Aneurysm in a Patient with Aortoiliac Occlusive Disease.

Asano S, Hayashida N, Shibata Y, Koizumi S, Ito T, Ikeuchi H, Hasegawa H, Abe S, Kabasawa M, Hirose N, Ohba M, Hirano M, Matsuo K, Murayama H.

Ann Vasc Dis. 2019 Mar 25;12(1):105-108. doi: 10.3400/avd.cr.18-00143.

35.

Physiological Properties of Photoautotrophic Microalgae and Cyanobacteria Relevant to Industrial Biomass Production.

Tsuzuki M, Okada K, Isoda H, Hirano M, Odaka T, Saijo H, Aruga R, Miyauchi H, Fujiwara S.

Mar Biotechnol (NY). 2019 Jun;21(3):406-415. doi: 10.1007/s10126-019-09890-1. Epub 2019 Mar 29.

PMID:
30927152
36.

Prognostic Factors of Malignant Peritoneal Mesothelioma Experienced in Japanese Peritoneal Metastasis Center.

Yonemura Y, Canbay E, Wakama S, Sako S, Ishibashi H, Hirano M, Motoi S, Mizumoto A, Takao N, Ichinose M, Noguchi K, Liu Y, Fushida S.

Gan To Kagaku Ryoho. 2019 Feb;46(2):395-399.

PMID:
30914572
37.

Analysis of Treatment Failure after Complete Cytoreductive Surgery for Peritoneal Metastasis from Appendiceal Mucinous Neoplasm at a Japanese High Volume Center for Peritoneal Surface Malignancy.

Yonemura Y, Canbay E, Wakama S, Sako S, Ishibashi H, Hirano M, Motoi S, Mizumoto A, Takao N, Ichinose M, Noguchi K, Liu Y, Fushida S, Li Y.

Gan To Kagaku Ryoho. 2019 Feb;46(2):251-258.

PMID:
30914528
38.

Alpha-1-Antitrypsin Promoter Improves the Efficacy of an Adeno-Associated Virus Vector for the Treatment of Mitochondrial Neurogastrointestinal Encephalomyopathy.

Cabrera-Pérez R, Vila-Julià F, Hirano M, Mingozzi F, Torres-Torronteras J, Martí R.

Hum Gene Ther. 2019 Aug;30(8):985-998. doi: 10.1089/hum.2018.217. Epub 2019 Apr 24.

PMID:
30900470
39.

Effect of Awareness and Habits of Oral Care on Life Satisfaction.

Hirano M, Imai H, Oya M.

Oral Health Prev Dent. 2019;17(2):131-138. doi: 10.3290/j.ohpd.a42204.

PMID:
30874253
40.

Cardiac Lymphatic Dysfunction Causes Drug-Eluting Stent-Induced Coronary Hyperconstricting Responses in Pigs In Vivo.

Amamizu H, Matsumoto Y, Morosawa S, Ohyama K, Uzuka H, Hirano M, Nishimiya K, Gokon Y, Watanabe-Asaka T, Hayashi M, Miyata S, Kamei T, Kawai Y, Shimokawa H.

Arterioscler Thromb Vasc Biol. 2019 Apr;39(4):741-753. doi: 10.1161/ATVBAHA.119.312396.

PMID:
30816801
41.

Correction to: Short-Term Symptomatic Relief in Gastroesophageal Reflux Disease: A Comparative Study of Esomeprazole and Vonoprazan.

Sakurai K, Suda H, Fujie S, Takeichi T, Okuda A, Murao T, Hasuda K, Hirano M, Ito K, Tsuruta K, Hattori M.

Dig Dis Sci. 2019 Jun;64(6):1724. doi: 10.1007/s10620-019-5464-6.

PMID:
30815827
42.

Aberrant Active cis-Regulatory Elements Associated with Downregulation of RET Finger Protein Overcome Chemoresistance in Glioblastoma.

Ranjit M, Hirano M, Aoki K, Okuno Y, Ohka F, Yamamichi A, Kato A, Maeda S, Motomura K, Matsuo K, Enomoto A, Ino Y, Todo T, Takahashi M, Wakabayashi T, Kato T, Natsume A.

Cell Rep. 2019 Feb 26;26(9):2274-2281.e5. doi: 10.1016/j.celrep.2019.01.109.

43.

Long-term outcomes after non-curative endoscopic submucosal dissection for early gastric cancer according to hospital volumes in Japan: a multicenter propensity-matched analysis.

Dohi O, Hatta W, Gotoda T, Naito Y, Oyama T, Kawata N, Takahashi A, Oka S, Hoteya S, Nakagawa M, Hirano M, Esaki M, Matsuda M, Ohnita K, Shimoda R, Yoshida M, Takada J, Tanaka K, Yamada S, Tsuji T, Ito H, Aoyagi H, Shimosegawa T.

Surg Endosc. 2019 Feb 25. doi: 10.1007/s00464-019-06710-4. [Epub ahead of print]

PMID:
30805782
44.

BCL6 Evolved to Enable Stress Tolerance in Vertebrates and Is Broadly Required by Cancer Cells to Adapt to Stress.

Fernando TM, Marullo R, Pera Gresely B, Phillip JM, Yang SN, Lundell-Smith G, Torregroza I, Ahn H, Evans T, Győrffy B, Privé GG, Hirano M, Melnick AM, Cerchietti L.

Cancer Discov. 2019 May;9(5):662-679. doi: 10.1158/2159-8290.CD-17-1444. Epub 2019 Feb 18.

PMID:
30777872
45.

Activation of Nrf2/Keap1 pathway by oral Dimethylfumarate administration alleviates oxidative stress and age-associated infertility might be delayed in the mouse ovary.

Akino N, Wada-Hiraike O, Isono W, Terao H, Honjo H, Miyamoto Y, Tanikawa M, Sone K, Hirano M, Harada M, Hirata T, Hirota Y, Koga K, Oda K, Fujii T, Osuga Y.

Reprod Biol Endocrinol. 2019 Feb 13;17(1):23. doi: 10.1186/s12958-019-0466-y.

46.

Immunogenicity and safety of the new MMR vaccine containing measles AIK-C, rubella Takahashi, and mumps RIT4385 strains in Japanese children: a randomized phase I/II clinical trial.

Nakayama T, Eda M, Hirano M, Goto W.

Hum Vaccin Immunother. 2019;15(5):1139-1144. doi: 10.1080/21645515.2019.1578591. Epub 2019 Apr 22.

47.

In Vitro and In Silico Evaluations of Binding Affinities of Perfluoroalkyl Substances to Baikal Seal and Human Peroxisome Proliferator-Activated Receptor α.

Ishibashi H, Hirano M, Kim EY, Iwata H.

Environ Sci Technol. 2019 Feb 19;53(4):2181-2188. doi: 10.1021/acs.est.8b07273. Epub 2019 Jan 31.

PMID:
30649875
48.

ADVERSE EFFECT OF MACULAR INTRARETINAL HEMORRHAGE ON THE PROGNOSIS OF SUBMACULAR HEMORRHAGE DUE TO RETINAL ARTERIAL MACROANEURYSM RUPTURE.

Doi S, Kimura S, Morizane Y, Hosokawa MM, Shiode Y, Hirano M, Toshima S, Takahashi K, Hosogi M, Fujiwara A, Okanouchi T, Inoue Y, Shiraga F.

Retina. 2019 Jan 14. doi: 10.1097/IAE.0000000000002460. [Epub ahead of print]

PMID:
30649079
49.

Development of a Shock-Wave Catheter Ablation System for Ventricular Tachyarrhythmias: Validation Study in Pigs In Vivo.

Morosawa S, Yamamoto H, Hirano M, Amamizu H, Uzuka H, Ohyama K, Hasebe Y, Nakano M, Fukuda K, Takayama K, Shimokawa H.

J Am Heart Assoc. 2019 Jan 22;8(2):e011038. doi: 10.1161/JAHA.118.011038.

50.

The influence of subretinal injection pressure on the microstructure of the monkey retina.

Takahashi K, Morizane Y, Hisatomi T, Tachibana T, Kimura S, Hosokawa MM, Shiode Y, Hirano M, Doi S, Toshima S, Araki R, Matsumae H, Kanzaki Y, Hosogi M, Yoshida A, Sonoda KH, Shiraga F.

PLoS One. 2018 Dec 31;13(12):e0209996. doi: 10.1371/journal.pone.0209996. eCollection 2018.

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