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Simultaneous Detection of Six Different Types of Pesticides by an Immunosensor Based on Surface Plasmon Resonance.

Miyake S, Hirakawa Y, Yamasaki T, Watanabe E, Harada A, Iwasa S, Narita H.

Anal Sci. 2019 Oct 18. doi: 10.2116/analsci.19P333. [Epub ahead of print] No abstract available.


The role of oxidative stress and hypoxia in renal disease.

Honda T, Hirakawa Y, Nangaku M.

Kidney Res Clin Pract. 2019 Sep 27. doi: 10.23876/j.krcp.19.063. [Epub ahead of print] Review.


Proliferative Fasciitis/Myositis Involving the Facial Muscles Including the Masseter Muscle: A Rare Cause of Trismus.

Nishi TM, Yamashita S, Hirakawa YN, Katsuki NE, Tago M, Yamashita SI.

Am J Case Rep. 2019 Sep 25;20:1411-1417. doi: 10.12659/AJCR.917193.


Prasugrel effectively reduces the platelet reactivity units in patients with genetically metabolic dysfunction of cytochrome P450 2C19 who are treated with long-term dual antiplatelet therapy after undergoing drug-eluting stent implantation.

Shimamatsu J, Sasaki KI, Katsuki Y, Kawasaki T, Murasato Y, Ajisaka H, Yokoi H, Tashiro H, Harada A, Hirakawa Y, Ishizaki Y, Ishimatsu T, Kagiyama K, Fukumoto Y, Kakuma T, Ueno T.

Heart Vessels. 2019 Sep 23. doi: 10.1007/s00380-019-01499-7. [Epub ahead of print]


Recombinant thrombomodulin prevented hepatic ischemia-reperfusion injury by inhibiting high-mobility group box 1 in rats.

Hirakawa Y, Tsuchishima M, Fukumura A, Kinoshita K, Hayashi N, Saito T, George J, Toshikuni N, Ueda Y, Tsutsumi M.

Eur J Pharmacol. 2019 Sep 19;863:172681. doi: 10.1016/j.ejphar.2019.172681. [Epub ahead of print]


Development of a direct competitive enzyme-linked immunosorbent assay for determination of the fungicide mepanipyrim and its metabolite.

Miyake S, Hirakawa Y, Yamasaki T, Watanabe E, Harada A, Adachi K, Iwasa S, Narita H.

J Pestic Sci. 2019 Aug 20;44(3):156-161. doi: 10.1584/jpestics.D19-029.


NT-proBNP and Risk of Dementia in a General Japanese Elderly Population: The Hisayama Study.

Nagata T, Ohara T, Hata J, Sakata S, Furuta Y, Yoshida D, Honda T, Hirakawa Y, Ide T, Kanba S, Kitazono T, Tsutsui H, Ninomiya T.

J Am Heart Assoc. 2019 Sep 3;8(17):e011652. doi: 10.1161/JAHA.118.011652. Epub 2019 Aug 24.


Ratios of serum eicosapentaenoic acid to arachidonic acid and docosahexaenoic acid to arachidonic acid were inversely associated with serum resistin levels: The Hisayama Study.

Higashioka M, Hirakawa Y, Kawamura R, Honda T, Hata J, Yoshida D, Takata Y, Kitazono T, Osawa H, Ninomiya T.

J Diabetes Investig. 2019 Aug 21. doi: 10.1111/jdi.13129. [Epub ahead of print]


New insight into transdermal drug delivery with supersaturated formulation based on co-amorphous system.

Hirakawa Y, Ueda H, Miyano T, Kamiya N, Goto M.

Int J Pharm. 2019 Oct 5;569:118582. doi: 10.1016/j.ijpharm.2019.118582. Epub 2019 Aug 2.


Smoking results in accumulation of ectopic fat in the liver.

Kato A, Li Y, Ota A, Naito H, Yamada H, Nihashi T, Hotta Y, Chiang C, Hirakawa Y, Aoyama A, Tamakoshi K, Yatsuya H.

Diabetes Metab Syndr Obes. 2019 Jul 9;12:1075-1080. doi: 10.2147/DMSO.S212495. eCollection 2019.


Prediction of delayed platelet engraftment after autologous stem cell transplantation for B-cell non-Hodgkin lymphoma.

Yamaguchi J, Chinen Y, Takimoto-Shimomura T, Nagata H, Muramatsu A, Kuriyama K, Ohshiro M, Hirakawa Y, Iwai T, Uchiyama H, Uoshima N, Kaneko H, Nakao M, Tsukamoto T, Shimura Y, Kobayashi T, Horiike S, Yokota I, Kuroda J; KOTOSG Investigators.

Leuk Lymphoma. 2019 Jul 18:1-8. doi: 10.1080/10428194.2019.1636982. [Epub ahead of print]


Challenges to Successful Community-based Integrated Approach to Dementia: A Qualitative Study.

Hirakawa Y, Horie K, Chiang C, Shimizu H, Andoh H, Aoyama A.

J Gerontol Soc Work. 2019 Aug-Sep;62(6):613-629. doi: 10.1080/01634372.2019.1640825. Epub 2019 Jul 10.


Immunological consequences following splenectomy in patients with liver cirrhosis.

Hirakawa Y, Ogata T, Sasada T, Yamashita T, Itoh K, Tanaka H, Okuda K.

Exp Ther Med. 2019 Jul;18(1):848-856. doi: 10.3892/etm.2019.7640. Epub 2019 Jun 3.


Trends in the prevalence of type 2 diabetes and prediabetes in a Japanese community, 1988-2012: the Hisayama Study.

Mukai N, Hata J, Hirakawa Y, Ohara T, Yoshida D, Nakamura U, Kitazono T, Ninomiya T.

Diabetol Int. 2018 Nov 3;10(3):198-205. doi: 10.1007/s13340-018-0380-0. eCollection 2019 Jul.


Health-related behavior of the people who neglect the specific health guidance for metabolic syndrome control.

Hirakawa Y, Chiang C, Yasuda Uemura M, Aoyama A.

Nagoya J Med Sci. 2019 May;81(2):199-205. doi: 10.18999/nagjms.81.2.199.


Association between Axial Length and Myopic Maculopathy: The Hisayama Study.

Hashimoto S, Yasuda M, Fujiwara K, Ueda E, Hata J, Hirakawa Y, Ninomiya T, Sonoda KH.

Ophthalmol Retina. 2019 Oct;3(10):867-873. doi: 10.1016/j.oret.2019.04.023. Epub 2019 Apr 26.


Gender differences in wishes and feelings regarding end-of-life care among Japanese elderly people living at home.

Hirakawa Y, He Y, Chiang C, Aoyama A.

J Rural Med. 2019 May;14(1):148-151. doi: 10.2185/jrm.2992. Epub 2019 May 30.


[A Case of Laparoscopic Hepatectomy and Combined Resection of Lymph Nodes and Ureter for Liver Metastasis after Colorectal Cancer Surgery, with Local Lymph Node Recurrence and Bilateral Hydronephrosis].

Sato T, Sakai H, Goto Y, Kojima S, Nomura Y, Nakayama G, Hirakawa Y, Mikagi K, Kawahara R, Ishikawa H, Hisaka T, Yasunaga M, Tanaka H, Akagi Y, Okuda K.

Gan To Kagaku Ryoho. 2019 Apr;46(4):751-753. Japanese.


Diverse function of plant peptide hormones in local signaling and development.

Hirakawa Y, Sawa S.

Curr Opin Plant Biol. 2019 Oct;51:81-87. doi: 10.1016/j.pbi.2019.04.005. Epub 2019 May 25. Review.


Association Between Serum β-Alanine and Risk of Dementia.

Hata J, Ohara T, Katakura Y, Shimizu K, Yamashita S, Yoshida D, Honda T, Hirakawa Y, Shibata M, Sakata S, Kitazono T, Kuhara S, Ninomiya T.

Am J Epidemiol. 2019 Sep 1;188(9):1637-1645. doi: 10.1093/aje/kwz116.


Diffuse large B cell lymphoma with chromosomal translocation t(14;19)(q32;q13) occurring in IgG4-related disease.

Kawaji Y, Nagata H, Muramatsu A, Kuriyama K, Ohshiro M, Hirakawa Y, Iwai T, Kobayashi T, Uchiyama H, Urata Y, Kuroda J.

Ann Hematol. 2019 Jul;98(7):1785-1787. doi: 10.1007/s00277-019-03688-w. Epub 2019 Apr 13. No abstract available.


Serum Ethylamine Levels as an Indicator of l-Theanine Consumption and the Risk of Type 2 Diabetes in a General Japanese Population: The Hisayama Study.

Ninomiya T, Kanzaki N, Hirakawa Y, Yoshinari M, Higashioka M, Honda T, Shibata M, Sakata S, Yoshida D, Teramoto T, Takemoto S, Nishimoto S, Hata J, Kitazono T.

Diabetes Care. 2019 Jul;42(7):1234-1240. doi: 10.2337/dc18-2655. Epub 2019 May 10.


Dairy consumption and risk of functional disability in an elderly Japanese population: the Hisayama Study.

Yoshida D, Ohara T, Hata J, Shibata M, Hirakawa Y, Honda T, Uchida K, Takasugi S, Kitazono T, Kiyohara Y, Ninomiya T.

Am J Clin Nutr. 2019 Jun 1;109(6):1664-1671. doi: 10.1093/ajcn/nqz040.


Measurement of prostaglandin metabolites is useful in diagnosis of small bowel ulcerations.

Matsuno Y, Umeno J, Esaki M, Hirakawa Y, Fuyuno Y, Okamoto Y, Hirano A, Yasukawa S, Hirai F, Matsui T, Hosomi S, Watanabe K, Hosoe N, Ogata H, Hisamatsu T, Yanai S, Kochi S, Kurahara K, Yao T, Torisu T, Kitazono T, Matsumoto T.

World J Gastroenterol. 2019 Apr 14;25(14):1753-1763. doi: 10.3748/wjg.v25.i14.1753.


Meaning and practices of spiritual care for older people with dementia: experiences of nurses and care workers.

Hirakawa Y, Yajima K, Chiang C, Aoyama A.

Psychogeriatrics. 2019 Apr 15. doi: 10.1111/psyg.12454. [Epub ahead of print]


Biomarkers of Dietary Omega-6 Fatty Acids and Incident Cardiovascular Disease and Mortality.

Marklund M, Wu JHY, Imamura F, Del Gobbo LC, Fretts A, de Goede J, Shi P, Tintle N, Wennberg M, Aslibekyan S, Chen TA, de Oliveira Otto MC, Hirakawa Y, Eriksen HH, Kröger J, Laguzzi F, Lankinen M, Murphy RA, Prem K, Samieri C, Virtanen J, Wood AC, Wong K, Yang WS, Zhou X, Baylin A, Boer JMA, Brouwer IA, Campos H, Chaves PHM, Chien KL, de Faire U, Djoussé L, Eiriksdottir G, El-Abbadi N, Forouhi NG, Michael Gaziano J, Geleijnse JM, Gigante B, Giles G, Guallar E, Gudnason V, Harris T, Harris WS, Helmer C, Hellenius ML, Hodge A, Hu FB, Jacques PF, Jansson JH, Kalsbeek A, Khaw KT, Koh WP, Laakso M, Leander K, Lin HJ, Lind L, Luben R, Luo J, McKnight B, Mursu J, Ninomiya T, Overvad K, Psaty BM, Rimm E, Schulze MB, Siscovick D, Skjelbo Nielsen M, Smith AV, Steffen BT, Steffen L, Sun Q, Sundström J, Tsai MY, Tunstall-Pedoe H, Uusitupa MIJ, van Dam RM, Veenstra J, Monique Verschuren WM, Wareham N, Willett W, Woodward M, Yuan JM, Micha R, Lemaitre RN, Mozaffarian D, Risérus U; Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Fatty Acids and Outcomes Research Consortium (FORCE).

Circulation. 2019 May 21;139(21):2422-2436. doi: 10.1161/CIRCULATIONAHA.118.038908.


Organellar DNA Polymerases in Complex Plastid-Bearing Algae.

Hirakawa Y, Watanabe A.

Biomolecules. 2019 Apr 7;9(4). pii: E140. doi: 10.3390/biom9040140.


Glucose Tolerance Levels and Circumpapillary Retinal Nerve Fiber Layer Thickness in a General Japanese Population: The Hisayama Study.

Fujiwara K, Yasuda M, Hata J, Hirakawa Y, Hashimoto S, Ueda E, Iwase A, Araie M, Yoshitomi T, Ninomiya T, Sonoda KH.

Am J Ophthalmol. 2019 Sep;205:140-146. doi: 10.1016/j.ajo.2019.03.031. Epub 2019 Apr 6.


Trends in the prevalence of airflow limitation in a general Japanese population: two serial cross-sectional surveys from the Hisayama Study.

Ogata H, Hirakawa Y, Matsumoto K, Hata J, Yoshida D, Fukuyama S, Inoue H, Kitazono T, Ninomiya T, Nakanishi Y.

BMJ Open. 2019 Mar 20;9(3):e023673. doi: 10.1136/bmjopen-2018-023673.


Prevalence of adult epilepsy in a general Japanese population: The Hisayama study.

Tanaka A, Hata J, Akamatsu N, Mukai N, Hirakawa Y, Yoshida D, Kishimoto H, Ohara T, Mizuno T, Tsuji S, Kitazono T, Ninomiya T.

Epilepsia Open. 2019 Jan 21;4(1):182-186. doi: 10.1002/epi4.12295. eCollection 2019 Mar.


Coffee Drinking and Risk of All-Cause Mortality and Cardiovascular Diseases.

Hirakawa Y.

Circ J. 2019 Mar 25;83(4):711-712. doi: 10.1253/circj.CJ-19-0157. Epub 2019 Mar 8. No abstract available.


Control of proliferation in the haploid meristem by CLE peptide signaling in Marchantia polymorpha.

Hirakawa Y, Uchida N, Yamaguchi YL, Tabata R, Ishida S, Ishizaki K, Nishihama R, Kohchi T, Sawa S, Bowman JL.

PLoS Genet. 2019 Mar 7;15(3):e1007997. doi: 10.1371/journal.pgen.1007997. eCollection 2019 Mar.


Association Between Genetic Risk and Development of Type 2 Diabetes in a General Japanese Population: The Hisayama Study.

Inaishi J, Hirakawa Y, Horikoshi M, Akiyama M, Higashioka M, Yoshinari M, Hata J, Mukai N, Kamatani Y, Momozawa Y, Kubo M, Ninomiya T.

J Clin Endocrinol Metab. 2019 Aug 1;104(8):3213-3222. doi: 10.1210/jc.2018-01782.


Taming chlorophylls by early eukaryotes underpinned algal interactions and the diversification of the eukaryotes on the oxygenated Earth.

Kashiyama Y, Yokoyama A, Shiratori T, Hess S, Not F, Bachy C, Gutierrez-Rodriguez A, Kawahara J, Suzaki T, Nakazawa M, Ishikawa T, Maruyama M, Wang M, Chen M, Gong Y, Seto K, Kagami M, Hamamoto Y, Honda D, Umetani T, Shihongi A, Kayama M, Matsuda T, Taira J, Yabuki A, Tsuchiya M, Hirakawa Y, Kawaguchi A, Nomura M, Nakamura A, Namba N, Matsumoto M, Tanaka T, Yoshino T, Higuchi R, Yamamoto A, Maruyama T, Yamaguchi A, Uzuka A, Miyagishima S, Tanifuji G, Kawachi M, Kinoshita Y, Tamiaki H.

ISME J. 2019 Aug;13(8):1899-1910. doi: 10.1038/s41396-019-0377-0. Epub 2019 Feb 26.


Involvement of Japanese Care Managers and Social Workers in Advance Care Planning.

Hirakawa Y, Chiang C, Yasuda Uemura M, Aoyama A.

J Soc Work End Life Palliat Care. 2018 Oct-Dec;14(4):315-327. doi: 10.1080/15524256.2018.1533912. Epub 2019 Jan 17.


Glycated haemoglobin (HbA1c) as a reliable option for detecting diabetes among the urban poor population in Bangladesh.

Chiang C, Aoyama A, Khalequzzaman M, Choudhury SR, Paul D, Rayna SE, Khan FA, Hirakawa Y, Iso H, Yatsuya H.

Eur J Public Health. 2019 Jan 10. doi: 10.1093/eurpub/cky275. [Epub ahead of print]


Longitudinal Changes of Physical Activity and Sedentary Time in the Middle-Aged and Older Japanese Population: The Hisayama Study.

Yonemoto K, Honda T, Kishimoto H, Yoshida D, Hata J, Mukai N, Shibata M, Hirakawa Y, Ninomiya T, Kumagai S.

J Phys Act Health. 2019 Feb 1;16(2):165-171. doi: 10.1123/jpah.2017-0701. Epub 2019 Jan 11.


Perceptions and behavior related to noncommunicable diseases among slum dwellers in a rapidly urbanizing city, Dhaka, Bangladesh: a qualitative study.

Al-Shoaibi AAA, Matsuyama A, Khalequzzaman M, Haseen F, Choudhury SR, Hoque BA, Chiang C, Hirakawa Y, Yatsuya H, Aoyama A.

Nagoya J Med Sci. 2018 Nov;80(4):559-569. doi: 10.18999/nagjms.80.4.559.


Perception and practice of 'healthy' diet in relation to noncommunicable diseases among the urban and rural people in northern Ethiopia: a community-based qualitative study.

Gebremariam LW, Aoyama A, Kahsay AB, Hirakawa Y, Chiang C, Yatsuya H, Matsuyama A.

Nagoya J Med Sci. 2018 Nov;80(4):451-464. doi: 10.18999/nagjms.80.4.451.


Obesity and mental health improvement following nutritional education focusing on gut microbiota composition in Japanese women: a randomised controlled trial.

Uemura M, Hayashi F, Ishioka K, Ihara K, Yasuda K, Okazaki K, Omata J, Suzutani T, Hirakawa Y, Chiang C, Aoyama A, Ohira T.

Eur J Nutr. 2018 Dec 6. doi: 10.1007/s00394-018-1873-0. [Epub ahead of print]


Effects of blood pressure lowering on cardiovascular events, in the context of regression to the mean: a systematic review of randomized trials.

Salam A, Atkins E, Sundström J, Hirakawa Y, Ettehad D, Emdin C, Neal B, Woodward M, Chalmers J, Berge E, Yusuf S, Rahimi K, Rodgers A; Blood Pressure Lowering Treatment Trialists’ Collaboration.

J Hypertens. 2019 Jan;37(1):16-23. doi: 10.1097/HJH.0000000000001994.


Serum Soluble Triggering Receptor Expressed on Myeloid Cells 2 as a Biomarker for Incident Dementia: The Hisayama Study.

Ohara T, Hata J, Tanaka M, Honda T, Yamakage H, Yoshida D, Inoue T, Hirakawa Y, Kusakabe T, Shibata M, Teraoka T, Kitazono T, Kanba S, Satoh-Asahara N, Ninomiya T.

Ann Neurol. 2019 Jan;85(1):47-58. doi: 10.1002/ana.25385. Epub 2018 Dec 28.


Targeting oxidative stress in diabetic kidney disease: a novel drug in an old pathway.

Hirakawa Y, Nangaku M.

Kidney Int. 2018 Dec;94(6):1038-1039. doi: 10.1016/j.kint.2018.10.004. No abstract available.


Development of Enzyme-Linked Immunosorbent Assay for Analysis of Total Aflatoxins Based on Monoclonal Antibody Reactive with Aflatoxins B1, B2, G1 and G2.

Yamasaki T, Miyake S, Sato N, Hirakawa Y, Iwasa S, Narita H, Watanabe T.

Shokuhin Eiseigaku Zasshi. 2018;59(5):200-205. doi: 10.3358/shokueishi.59.200.


Development and validation of modified risk prediction models for cardiovascular disease and its subtypes: The Hisayama Study.

Honda T, Yoshida D, Hata J, Hirakawa Y, Ishida Y, Shibata M, Sakata S, Kitazono T, Ninomiya T.

Atherosclerosis. 2018 Dec;279:38-44. doi: 10.1016/j.atherosclerosis.2018.10.014. Epub 2018 Oct 17.


Puromycin selection for stable transfectants of the oyster-infecting parasite Perkinsus marinus.

Sakamoto H, Hirakawa Y, Ishida KI, Keeling PJ, Kita K, Matsuzaki M.

Parasitol Int. 2019 Apr;69:13-16. doi: 10.1016/j.parint.2018.10.011. Epub 2018 Oct 30.


Objectively measured sedentary time and diabetes mellitus in a general Japanese population: The Hisayama Study.

Honda T, Kishimoto H, Mukai N, Hata J, Yoshida D, Hirakawa Y, Shibata M, Ohara T, Kumagai S, Ninomiya T.

J Diabetes Investig. 2019 May;10(3):809-816. doi: 10.1111/jdi.12968. Epub 2018 Nov 29.


A potential novel pathological implication of serum soluble triggering receptor expressed on myeloid cell 2 in insulin resistance in a general Japanese population: The Hisayama study.

Tanaka M, Honda T, Yamakage H, Hata J, Yoshida D, Hirakawa Y, Shibata M, Inoue T, Kusakabe T, Satoh-Asahara N, Ninomiya T.

Diabetes Res Clin Pract. 2018 Dec;146:225-232. doi: 10.1016/j.diabres.2018.10.007. Epub 2018 Oct 16.


Enhanced expression of nidogen 1 around the nest of basal cell carcinoma compared with that around squamous cell carcinoma.

Hirakawa Y, Futaki S, Tanizaki H, Furukawa F, Maemura K, Kondo Y, Moriwaki S.

Med Mol Morphol. 2019 Jun;52(2):99-105. doi: 10.1007/s00795-018-0207-x. Epub 2018 Oct 1.


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