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Items: 1 to 50 of 146

1.

MAPK Erk5 in leptin receptor-expressing neurons controls body weight and systemic energy homeostasis in female mice.

Horie T, Park G, Inaba Y, Hashiuchi E, Iezaki T, Tokumura K, Fukasawa K, Yamada T, Hiraiwa M, Kitaguchi Y, Kamada H, Kaneda K, Tanaka T, Inoue H, Hinoi E.

Endocrinology. 2019 Sep 25. pii: en.2019-00090. doi: 10.1210/en.2019-00090. [Epub ahead of print]

PMID:
31555819
2.

The L-type amino acid transporter LAT1 inhibits osteoclastogenesis and maintains bone homeostasis through the mTORC1 pathway.

Ozaki K, Yamada T, Horie T, Ishizaki A, Hiraiwa M, Iezaki T, Park G, Fukasawa K, Kamada H, Tokumura K, Motono M, Kaneda K, Ogawa K, Ochi H, Sato S, Kobayashi Y, Shi YB, Taylor PM, Hinoi E.

Sci Signal. 2019 Jul 9;12(589). pii: eaaw3921. doi: 10.1126/scisignal.aaw3921.

PMID:
31289211
3.

Daily intake of polyamine-rich Saccharomyces cerevisiae S631 prevents osteoclastic activation and bone loss in ovariectomized mice.

Yamada T, Park G, Node J, Ozaki K, Hiraiwa M, Kitaguchi Y, Kaneda K, Hiramoto S, Hinoi E.

Food Sci Biotechnol. 2019 Feb 6;28(4):1241-1245. doi: 10.1007/s10068-019-00561-4. eCollection 2019 Aug.

PMID:
31275725
4.

mTORC1 Activation in Osteoclasts Prevents Bone Loss in a Mouse Model of Osteoporosis.

Hiraiwa M, Ozaki K, Yamada T, Iezaki T, Park G, Fukasawa K, Horie T, Kamada H, Tokumura K, Motono M, Kaneda K, Hinoi E.

Front Pharmacol. 2019 Jun 13;10:684. doi: 10.3389/fphar.2019.00684. eCollection 2019.

5.

Eribulin mesilate versus vinorelbine in women with locally recurrent or metastatic breast cancer: A randomised clinical trial.

Yuan P, Hu X, Sun T, Li W, Zhang Q, Cui S, Cheng Y, Ouyang Q, Wang X, Chen Z, Hiraiwa M, Saito K, Funasaka S, Xu B.

Eur J Cancer. 2019 May;112:57-65. doi: 10.1016/j.ejca.2019.02.002. Epub 2019 Mar 29.

6.

Longitudinal eigenvibration of multilayer colloidal crystals and the effect of nanoscale contact bridges.

Abi Ghanem M, Khanolkar A, Wallen SP, Helwig M, Hiraiwa M, Maznev AA, Vogel N, Boechler N.

Nanoscale. 2019 Mar 21;11(12):5655-5665. doi: 10.1039/c8nr08453j.

PMID:
30865190
7.

Hypoxia affects Slc7a5 expression through HIF-2╬▒ in differentiated neuronal cells.

Onishi Y, Hiraiwa M, Kamada H, Iezaki T, Yamada T, Kaneda K, Hinoi E.

FEBS Open Bio. 2019 Jan 7;9(2):241-247. doi: 10.1002/2211-5463.12559. eCollection 2019 Feb.

8.

Thrips as a supplementary pollinator in an orchid with granular pollinia: is this mutualism?

Suetsugu K, Tetsu S, Hiraiwa MK, Tsutsumi T.

Ecology. 2019 Feb;100(2):e02535. doi: 10.1002/ecy.2535. Epub 2018 Nov 12. No abstract available.

PMID:
30307033
9.

Translational Control of Sox9 RNA by mTORC1 Contributes to Skeletogenesis.

Iezaki T, Horie T, Fukasawa K, Kitabatake M, Nakamura Y, Park G, Onishi Y, Ozaki K, Kanayama T, Hiraiwa M, Kitaguchi Y, Kaneda K, Manabe T, Ishigaki Y, Ohno M, Hinoi E.

Stem Cell Reports. 2018 Jul 10;11(1):228-241. doi: 10.1016/j.stemcr.2018.05.020. Epub 2018 Jun 28.

10.

The MAPK Erk5 is necessary for proper skeletogenesis involving a Smurf-Smad-Sox9 molecular axis.

Iezaki T, Fukasawa K, Horie T, Park G, Robinson S, Nakaya M, Fujita H, Onishi Y, Ozaki K, Kanayama T, Hiraiwa M, Kitaguchi Y, Kaneda K, Yoneda Y, Takarada T, Guo XE, Kurose H, Hinoi E.

Development. 2018 Jul 26;145(14). pii: dev164004. doi: 10.1242/dev.164004.

11.

Hypoxic Stress Upregulates the Expression of Slc38a1 in Brown Adipocytes via Hypoxia-Inducible Factor-1╬▒.

Horie T, Fukasawa K, Iezaki T, Park G, Onishi Y, Ozaki K, Kanayama T, Hiraiwa M, Kitaguchi Y, Kaneda K, Hinoi E.

Pharmacology. 2018;101(1-2):64-71. doi: 10.1159/000480405. Epub 2017 Oct 25.

PMID:
29065407
12.

Low functional diversity promotes niche changes in natural island pollinator communities.

Hiraiwa MK, Ushimaru A.

Proc Biol Sci. 2017 Jan 11;284(1846). pii: 20162218. doi: 10.1098/rspb.2016.2218.

13.

Laser-Induced Spallation of Microsphere Monolayers.

Hiraiwa M, Stossel M, Khanolkar A, Wang J, Boechler N.

Langmuir. 2016 Aug 9;32(31):7730-4. doi: 10.1021/acs.langmuir.6b00982. Epub 2016 Aug 1.

PMID:
27409715
14.

Complex Contact-Based Dynamics of Microsphere Monolayers Revealed by Resonant Attenuation of Surface Acoustic Waves.

Hiraiwa M, Abi Ghanem M, Wallen SP, Khanolkar A, Maznev AA, Boechler N.

Phys Rev Lett. 2016 May 13;116(19):198001. doi: 10.1103/PhysRevLett.116.198001. Epub 2016 May 11.

PMID:
27232047
15.

Amperometric immunosensor for rapid detection of Mycobacterium tuberculosis.

Hiraiwa M, Kim JH, Lee HB, Inoue S, Becker AL, Weigel KM, Cangelosi GA, Lee KH, Chung JH.

J Micromech Microeng. 2015;25:055013.

16.

Brief report: large individual variation in outcomes of autistic children receiving low-intensity behavioral interventions in community settings.

Kamio Y, Haraguchi H, Miyake A, Hiraiwa M.

Child Adolesc Psychiatry Ment Health. 2015 Mar 25;9:6. doi: 10.1186/s13034-015-0039-6. eCollection 2015.

17.

Semi-automated, occupationally safe immunofluorescence microtip sensor for rapid detection of Mycobacterium cells in sputum.

Inoue S, Becker AL, Kim JH, Shu Z, Soelberg SD, Weigel KM, Hiraiwa M, Cairns A, Lee HB, Furlong CE, Oh K, Lee KH, Gao D, Chung JH, Cangelosi GA.

PLoS One. 2014 Jan 22;9(1):e86018. doi: 10.1371/journal.pone.0086018. eCollection 2014.

18.

GPR37 protein trafficking to the plasma membrane regulated by prosaposin and GM1 gangliosides promotes cell viability.

Lundius EG, Vukojevic V, Hertz E, Stroth N, Cederlund A, Hiraiwa M, Terenius L, Svenningsson P.

J Biol Chem. 2014 Feb 21;289(8):4660-73. doi: 10.1074/jbc.M113.510883. Epub 2013 Dec 26.

19.

Nanotips for single-step preparation of DNA for qPCR analysis.

Kalyanasundaram D, Kim JH, Fotouhi G, Lee HB, Hiraiwa M, Oh K, Lee KH, Chung JH.

Analyst. 2013 Jun 7;138(11):3135-8. doi: 10.1039/c3an00170a.

PMID:
23594970
20.

Electrolyte-free Amperometric Immunosensor using a Dendritic Nanotip.

Kim JH, Hiraiwa M, Lee HB, Lee KH, Cangelosi GA, Chung JH.

RSC Adv. 2013;3(13):4281-4287.

21.

High-Functioning Autistic Children: -From a physician's perspective-.

Hiraiwa M.

Japan Med Assoc J. 2012 Jul;55(4):298-302. No abstract available.

PMID:
25237236
22.

Inhibition of oligopeptide transporter suppress growth of human pancreatic cancer cells.

Mitsuoka K, Kato Y, Miyoshi S, Murakami Y, Hiraiwa M, Kubo Y, Nishimura S, Tsuji A.

Eur J Pharm Sci. 2010 Jun 14;40(3):202-8. doi: 10.1016/j.ejps.2010.03.010. Epub 2010 Mar 20.

PMID:
20307658
23.

Protective effect of all-trans retinoic acid on NMDA-induced neuronal cell death in rat retina.

Sakamoto K, Hiraiwa M, Saito M, Nakahara T, Sato Y, Nagao T, Ishii K.

Eur J Pharmacol. 2010 Jun 10;635(1-3):56-61. doi: 10.1016/j.ejphar.2010.03.001. Epub 2010 Mar 19.

PMID:
20303946
24.

Biochemistry and neurobiology of prosaposin: a potential therapeutic neuro-effector.

Misasi R, Hozumi I, Inuzuka T, Capozzi A, Mattei V, Kuramoto Y, Shimeno H, Soeda S, Azuma N, Yamauchi T, Hiraiwa M.

Cent Nerv Syst Agents Med Chem. 2009 Jun;9(2):119-31. Review.

PMID:
20021345
25.

The crystal structure of sphingosine-1-phosphate in complex with a Fab fragment reveals metal bridging of an antibody and its antigen.

Wojciak JM, Zhu N, Schuerenberg KT, Moreno K, Shestowsky WS, Hiraiwa M, Sabbadini R, Huxford T.

Proc Natl Acad Sci U S A. 2009 Oct 20;106(42):17717-22. doi: 10.1073/pnas.0906153106. Epub 2009 Oct 7. Erratum in: Proc Natl Acad Sci U S A. 2009 Nov 3;106(44):18873. Proc Natl Acad Sci U S A. 2010 Feb 9;107(6):2723.

26.

Production and characterization of monoclonal anti-sphingosine-1-phosphate antibodies.

O'Brien N, Jones ST, Williams DG, Cunningham HB, Moreno K, Visentin B, Gentile A, Vekich J, Shestowsky W, Hiraiwa M, Matteo R, Cavalli A, Grotjahn D, Grant M, Hansen G, Campbell MA, Sabbadini R.

J Lipid Res. 2009 Nov;50(11):2245-57. doi: 10.1194/jlr.M900048-JLR200. Epub 2009 Jun 9.

27.

Neurotrophic signalling pathway triggered by prosaposin in PC12 cells occurs through lipid rafts.

Sorice M, Molinari S, Di Marzio L, Mattei V, Tasciotti V, Ciarlo L, Hiraiwa M, Garofalo T, Misasi R.

FEBS J. 2008 Oct;275(19):4903-12. doi: 10.1111/j.1742-4658.2008.06630.x.

28.

Molecular mechanism for neuro-protective effect of prosaposin against oxidative stress: its regulation of dimeric transcription factor formation.

Ochiai T, Takenaka Y, Kuramoto Y, Kasuya M, Fukuda K, Kimura M, Shimeno H, Misasi R, Hiraiwa M, Soeda S.

Biochim Biophys Acta. 2008 Dec;1780(12):1441-7. doi: 10.1016/j.bbagen.2008.07.010. Epub 2008 Jul 28.

PMID:
18706485
29.

Bacterial community structures in MBRs treating municipal wastewater: relationship between community stability and reactor performance.

Miura Y, Hiraiwa MN, Ito T, Itonaga T, Watanabe Y, Okabe S.

Water Res. 2007 Feb;41(3):627-37. Epub 2006 Dec 20.

PMID:
17184810
30.

Prosaposin is a novel androgen-regulated gene in prostate cancer cell line LNCaP.

Koochekpour S, Lee TJ, Wang R, Sun Y, Delorme N, Hiraiwa M, Grabowski GA, Culig Z, Minokadeh A.

J Cell Biochem. 2007 Jun 1;101(3):631-41.

PMID:
17171640
31.

Amplification and overexpression of prosaposin in prostate cancer.

Koochekpour S, Zhuang YJ, Beroukhim R, Hsieh CL, Hofer MD, Zhau HE, Hiraiwa M, Pattan DY, Ware JL, Luftig RB, Sandhoff K, Sawyers CL, Pienta KJ, Rubin MA, Vessella RL, Sellers WR, Sartor O.

Genes Chromosomes Cancer. 2005 Dec;44(4):351-64.

PMID:
16080200
32.

Saposin C stimulates growth and invasion, activates p42/44 and SAPK/JNK signaling pathways of MAPK and upregulates uPA/uPAR expression in prostate cancer and stromal cells.

Koochekpour S, Sartor O, Hiraiwa M, Lee TJ, Rayford W, Remmel N, Sandhoff K, Minokadeh A, Patten DY.

Asian J Androl. 2005 Jun;7(2):147-58.

33.

Prosaptide TX14A stimulates growth, migration, and invasion and activates the Raf-MEK-ERK-RSK-Elk-1 signaling pathway in prostate cancer cells.

Koochekpour S, Sartor O, Lee TJ, Zieske A, Patten DY, Hiraiwa M, Sandhoff K, Remmel N, Minokadeh A.

Prostate. 2004 Oct 1;61(2):114-23.

PMID:
15305334
34.

Prosaposin: a new player in cell death prevention of U937 monocytic cells.

Misasi R, Garofalo T, Di Marzio L, Mattei V, Gizzi C, Hiraiwa M, Pavan A, Grazia Cifone M, Sorice M.

Exp Cell Res. 2004 Aug 1;298(1):38-47.

PMID:
15242760
35.

Hippocampal prosaposin changes during stress: a glucocorticoid-independent event.

Scaccianoce S, Mattei V, Del Bianco P, Gizzi C, Sorice M, Hiraiwa M, Misasi R.

Hippocampus. 2004;14(3):275-80.

PMID:
15132426
36.

Regulation of gene expression in response to brain injury: enhanced expression and alternative splicing of rat prosaposin (SGP-1) mRNA in injured brain.

Hiraiwa M, Liu J, Lu AG, Wang CY, Misasi R, Yamauchi T, Hozumi I, Inuzuka T, O'Brien JS.

J Neurotrauma. 2003 Aug;20(8):755-65.

PMID:
12965054
37.

Transactivation of the fucosyltransferase VII gene by human T-cell leukemia virus type 1 Tax through a variant cAMP-responsive element.

Hiraiwa N, Yabuta T, Yoritomi K, Hiraiwa M, Tanaka Y, Suzuki T, Yoshida M, Kannagi R.

Blood. 2003 May 1;101(9):3615-21. Epub 2002 Dec 27.

PMID:
12506041
38.

Saposins (sap) A and C activate the degradation of galactosylsphingosine.

Harzer K, Hiraiwa M, Paton BC.

FEBS Lett. 2001 Nov 9;508(1):107-10.

39.

A retro-inverso Prosaptide D5 promotes a myelination process in developing rats.

Hiraiwa M, Campana WM, Wang CY, Otero DA, O'Brien JS.

Brain Res Dev Brain Res. 2001 May 31;128(1):73-6.

PMID:
11356264
40.

Cathepsin A/protective protein: an unusual lysosomal multifunctional protein.

Hiraiwa M.

Cell Mol Life Sci. 1999 Dec;56(11-12):894-907. Review.

PMID:
11212324
41.

Neuroprotective effect of retro-inverso Prosaptide D5 on focal cerebral ischemia in rat.

Lu AG, Otero DA, Hiraiwa M, O'Brien JS.

Neuroreport. 2000 Jun 5;11(8):1791-4.

PMID:
10852246
42.
43.

[Pulmonary aspergillosis as a terminal event in AIDS patient].

Ando M, Hiraiwa M, Kawai M, Oki M, Saka H, Yamanaka K, Matsunaga S, Utsumi M, Ichihara S, Tuji T, Nishimura Y.

Arerugi. 1999 Oct;48(10):1180-3. Japanese. No abstract available.

PMID:
10554405
44.

Administration of prosaposin ameliorates spatial learning disturbance and reduces cavity formation following stab wounds in rat brain.

Hozumi I, Hiraiwa M, Inuzuka T, Yoneoka Y, Akiyama K, Tanaka R, Kikugawa K, Nakano R, Tsuji S, O'Brien JS.

Neurosci Lett. 1999 May 21;267(1):73-6.

PMID:
10400252
45.

Prosaposin: a myelinotrophic protein that promotes expression of myelin constituents and is secreted after nerve injury.

Hiraiwa M, Campana WM, Mizisin AP, Mohiuddin L, O'Brien JS.

Glia. 1999 Jun;26(4):353-60.

PMID:
10383054
46.

Secretion of prosaposin, a multifunctional protein, by breast cancer cells.

Campana WM, O'Brien JS, Hiraiwa M, Patton S.

Biochim Biophys Acta. 1999 May 24;1427(3):392-400.

PMID:
10350655
47.

Colocalization and complex formation between prosaposin and monosialoganglioside GM3 in neural cells.

Misasi R, Sorice M, Garofalo T, Griggi T, Campana WM, Giammatteo M, Pavan A, Hiraiwa M, Pontieri GM, O'Brien JS.

J Neurochem. 1998 Dec;71(6):2313-21.

48.

Prosaposin prevents programmed cell death of rat cerebellar granule neurons in culture.

Tsuboi K, Hiraiwa M, O'Brien JS.

Brain Res Dev Brain Res. 1998 Oct 1;110(2):249-55.

PMID:
9748612
49.

Gene expression of fucosyl- and sialyl-transferases which synthesize sialyl Lewisx, the carbohydrate ligands for E-selectin, in human breast cancer.

Matsuura N, Narita T, Hiraiwa N, Hiraiwa M, Murai H, Iwase T, Funahashi H, Imai T, Takagi H, Kannagi R.

Int J Oncol. 1998 May;12(5):1157-64.

PMID:
9538143
50.

Cloning, expression and map assignment of chicken prosaposin.

Azuma N, Seo HC, Lie O, Fu Q, Gould RM, Hiraiwa M, Burt DW, Paton IR, Morrice DR, O'Brien JS, Kishimoto Y.

Biochem J. 1998 Feb 15;330 ( Pt 1):321-7.

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