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Items: 1 to 50 of 305

1.

Incidence of dementia in patients with adult-onset epilepsy of unknown causes.

Kawakami O, Koike Y, Ando T, Sugiura M, Kato H, Hiraga K, Kito H, Kondo H.

J Neurol Sci. 2018 Dec 15;395:71-76. doi: 10.1016/j.jns.2018.09.010. Epub 2018 Sep 13. No abstract available.

PMID:
30292966
2.

RAQET: Large-scale two-component relativistic quantum chemistry program package.

Hayami M, Seino J, Nakajima Y, Nakano M, Ikabata Y, Yoshikawa T, Oyama T, Hiraga K, Hirata S, Nakai H.

J Comput Chem. 2018 Oct 15;39(27):2333-2344. doi: 10.1002/jcc.25364. Epub 2018 Sep 20.

PMID:
30238477
3.

"Site and Mutation"-Specific Predictions Enable Minimal Directed Evolution Libraries.

Moore JC, Rodriguez-Granillo A, Crespo A, Govindarajan S, Welch M, Hiraga K, Lexa K, Marshall N, Truppo MD.

ACS Synth Biol. 2018 Jul 20;7(7):1730-1741. doi: 10.1021/acssynbio.7b00359. Epub 2018 Jun 12.

PMID:
29782150
4.

Production of 4-Hydroxybenzoic Acid by an Aerobic Growth-Arrested Bioprocess Using Metabolically Engineered Corynebacterium glutamicum.

Kitade Y, Hashimoto R, Suda M, Hiraga K, Inui M.

Appl Environ Microbiol. 2018 Mar 1;84(6). pii: e02587-17. doi: 10.1128/AEM.02587-17. Print 2018 Mar 15.

5.

Structural basis of autoinhibition and activation of the DNA-targeting ADP-ribosyltransferase pierisin-1.

Oda T, Hirabayashi H, Shikauchi G, Takamura R, Hiraga K, Minami H, Hashimoto H, Yamamoto M, Wakabayashi K, Shimizu T, Sato M.

J Biol Chem. 2017 Sep 15;292(37):15445-15455. doi: 10.1074/jbc.M117.776641. Epub 2017 Aug 1.

6.

Comparison of Nutritional Risk Scores for Predicting Mortality in Japanese Chronic Hemodialysis Patients.

Takahashi H, Inoue K, Shimizu K, Hiraga K, Takahashi E, Otaki K, Yoshikawa T, Furuta K, Tokunaga C, Sakakibara T, Ito Y; Tokai Renal Nutrition Study Group.

J Ren Nutr. 2017 May;27(3):201-206. doi: 10.1053/j.jrn.2016.12.005. Epub 2017 Feb 20.

PMID:
28215493
7.

Metabolic engineering of Corynebacterium glutamicum for shikimate overproduction by growth-arrested cell reaction.

Kogure T, Kubota T, Suda M, Hiraga K, Inui M.

Metab Eng. 2016 Nov;38:204-216. doi: 10.1016/j.ymben.2016.08.005. Epub 2016 Aug 20.

PMID:
27553883
8.

Response to Comment on "A bacterium that degrades and assimilates poly(ethylene terephthalate)".

Yoshida S, Hiraga K, Takehana T, Taniguchi I, Yamaji H, Maeda Y, Toyohara K, Miyamoto K, Kimura Y, Oda K.

Science. 2016 Aug 19;353(6301):759. doi: 10.1126/science.aaf8625.

9.

Production of para-aminobenzoate by genetically engineered Corynebacterium glutamicum and non-biological formation of an N-glucosyl byproduct.

Kubota T, Watanabe A, Suda M, Kogure T, Hiraga K, Inui M.

Metab Eng. 2016 Nov;38:322-330. doi: 10.1016/j.ymben.2016.07.010. Epub 2016 Jul 26.

PMID:
27471069
10.

Ideonella sakaiensis sp. nov., isolated from a microbial consortium that degrades poly(ethylene terephthalate).

Tanasupawat S, Takehana T, Yoshida S, Hiraga K, Oda K.

Int J Syst Evol Microbiol. 2016 Aug;66(8):2813-8. doi: 10.1099/ijsem.0.001058. Epub 2016 Apr 5.

PMID:
27045688
11.

A bacterium that degrades and assimilates poly(ethylene terephthalate).

Yoshida S, Hiraga K, Takehana T, Taniguchi I, Yamaji H, Maeda Y, Toyohara K, Miyamoto K, Kimura Y, Oda K.

Science. 2016 Mar 11;351(6278):1196-9. doi: 10.1126/science.aad6359.

12.

A Cell-Based Internalization and Degradation Assay with an Activatable Fluorescence-Quencher Probe as a Tool for Functional Antibody Screening.

Li Y, Liu PC, Shen Y, Snavely MD, Hiraga K.

J Biomol Screen. 2015 Aug;20(7):869-75. doi: 10.1177/1087057115588511. Epub 2015 May 29.

13.

Functional Characterization of Corynebacterium alkanolyticum β-Xylosidase and Xyloside ABC Transporter in Corynebacterium glutamicum.

Watanabe A, Hiraga K, Suda M, Yukawa H, Inui M.

Appl Environ Microbiol. 2015 Jun 15;81(12):4173-83. doi: 10.1128/AEM.00792-15. Epub 2015 Apr 10.

14.

The effects analysis of two neonicotinoid insecticides on in vitro maturation of porcine oocytes using hanging drop monoculture method.

Ishikawa S, Hiraga K, Hiradate Y, Tanemura K.

J Vet Med Sci. 2015 Jun;77(6):725-8. doi: 10.1292/jvms.15-0008. Epub 2015 Feb 6.

15.

Identification and expression analysis of a gene encoding a shikimate transporter of Corynebacterium glutamicum.

Kubota T, Tanaka Y, Takemoto N, Hiraga K, Yukawa H, Inui M.

Microbiology. 2015 Feb;161(Pt 2):254-63. doi: 10.1099/mic.0.083733-0. Epub 2014 Nov 18.

PMID:
25406451
16.

The stereoselective synthesis of α-amino aldols starting from terminal alkynes.

Miura T, Nakamuro T, Hiraga K, Murakami M.

Chem Commun (Camb). 2014 Sep 18;50(72):10474-7. doi: 10.1039/c4cc04786a.

PMID:
25068433
17.

Usefulness of Preoperative Surgical Simulation with Three-Dimensional Fusion Images for Resection of Cerebral Cavernous Malformations Near Broca's Area.

Takahashi S, Tanizaki Y, Akaji K, Kano T, Hiraga K, Mihara B.

Case Rep Neurol Med. 2014;2014:853425. doi: 10.1155/2014/853425. Epub 2014 Apr 14.

18.

Chorismate-dependent transcriptional regulation of quinate/shikimate utilization genes by LysR-type transcriptional regulator QsuR in Corynebacterium glutamicum: carbon flow control at metabolic branch point.

Kubota T, Tanaka Y, Takemoto N, Watanabe A, Hiraga K, Inui M, Yukawa H.

Mol Microbiol. 2014 Apr;92(2):356-68. doi: 10.1111/mmi.12560. Epub 2014 Mar 10.

19.

Hanging drop monoculture for selection of optimal antioxidants during in vitro maturation of porcine oocytes.

Ishikawa S, Machida R, Hiraga K, Hiradate Y, Suda Y, Tanemura K.

Reprod Domest Anim. 2014 Apr;49(2):e26-30. doi: 10.1111/rda.12289.

PMID:
24629146
20.

Stereoselective synthesis of 2,3-dihydropyrroles from terminal alkynes, azides, and α,β-unsaturated aldehydes via N-sulfonyl-1,2,3-triazoles.

Miura T, Tanaka T, Hiraga K, Stewart SG, Murakami M.

J Am Chem Soc. 2013 Sep 18;135(37):13652-5. doi: 10.1021/ja407166r. Epub 2013 Sep 4.

PMID:
23988194
21.

Regiocontrolled synthesis of polysubstituted pyrroles starting from terminal alkynes, sulfonyl azides, and allenes.

Miura T, Hiraga K, Biyajima T, Nakamuro T, Murakami M.

Org Lett. 2013 Jul 5;15(13):3298-301. doi: 10.1021/ol401340u. Epub 2013 Jun 18.

PMID:
23777199
22.

Identification of a gene involved in plasmid structural instability in Corynebacterium glutamicum.

Kitade Y, Okino S, Gunji W, Hiraga K, Suda M, Suzuki N, Inui M, Yukawa H.

Appl Microbiol Biotechnol. 2013 Sep;97(18):8219-26. doi: 10.1007/s00253-013-4934-6. Epub 2013 May 24.

PMID:
23703324
23.
24.

Characterization of shikimate dehydrogenase homologues of Corynebacterium glutamicum.

Kubota T, Tanaka Y, Hiraga K, Inui M, Yukawa H.

Appl Microbiol Biotechnol. 2013 Sep;97(18):8139-49. doi: 10.1007/s00253-012-4659-y. Epub 2013 Jan 10.

PMID:
23306642
25.

Engineering of Corynebacterium glutamicum for high-yield L-valine production under oxygen deprivation conditions.

Hasegawa S, Suda M, Uematsu K, Natsuma Y, Hiraga K, Jojima T, Inui M, Yukawa H.

Appl Environ Microbiol. 2013 Feb;79(4):1250-7. doi: 10.1128/AEM.02806-12. Epub 2012 Dec 14.

26.

Contribution of spinal galectin-3 to acute herpetic allodynia in mice.

Takasaki I, Taniguchi K, Komatsu F, Sasaki A, Andoh T, Nojima H, Shiraki K, Hsu DK, Liu FT, Kato I, Hiraga K, Kuraishi Y.

Pain. 2012 Mar;153(3):585-92. doi: 10.1016/j.pain.2011.11.022. Epub 2011 Dec 24.

PMID:
22197693
27.

Improvement of the redox balance increases L-valine production by Corynebacterium glutamicum under oxygen deprivation conditions.

Hasegawa S, Uematsu K, Natsuma Y, Suda M, Hiraga K, Jojima T, Inui M, Yukawa H.

Appl Environ Microbiol. 2012 Feb;78(3):865-75. doi: 10.1128/AEM.07056-11. Epub 2011 Dec 2.

28.

Natural dissociation of olivine to (Mg,Fe)SiO3 perovskite and magnesiowustite in a shocked Martian meteorite.

Miyahara M, Ohtani E, Ozawa S, Kimura M, El Goresy A, Sakai T, Nagase T, Hiraga K, Hirao N, Ohishi Y.

Proc Natl Acad Sci U S A. 2011 Apr 12;108(15):5999-6003. doi: 10.1073/pnas.1016921108. Epub 2011 Mar 28.

29.

Severe parkinsonism following endoscopic third ventriculostomy for non-communicating hydrocephalus--case report.

Akiyama T, Tanizaki Y, Akaji K, Hiraga K, Akiyama T, Takao M, Ohira T.

Neurol Med Chir (Tokyo). 2011;51(1):60-3.

30.

Coesite and stishovite in a shocked lunar meteorite, Asuka-881757, and impact events in lunar surface.

Ohtani E, Ozawa S, Miyahara M, Ito Y, Mikouchi T, Kimura M, Arai T, Sato K, Hiraga K.

Proc Natl Acad Sci U S A. 2011 Jan 11;108(2):463-6. doi: 10.1073/pnas.1009338108. Epub 2010 Dec 27.

31.

Salt effect on substrate specificity of a subtilisin-like halophilic protease.

Okamoto DN, Kondo MY, Hiraga K, Juliano MA, Juliano L, Gouvea IE, Oda K.

Protein Pept Lett. 2010 Jun;17(6):796-802.

PMID:
20205649
32.

Development of a predicting tool for survival of terminally ill cancer patients.

Hyodo I, Morita T, Adachi I, Shima Y, Yoshizawa A, Hiraga K.

Jpn J Clin Oncol. 2010 May;40(5):442-8. doi: 10.1093/jjco/hyp182. Epub 2010 Jan 18.

PMID:
20085908
33.

An alkaline serine-proteinase from a bacterium isolated from bat feces: purification and characterization.

Tanskul S, Hiraga K, Takada K, Rungratchote S, Suntinanalert P, Oda K.

Biosci Biotechnol Biochem. 2009 Nov;73(11):2393-8. Epub 2009 Nov 7.

34.

Selection and structure of hyperactive inteins: peripheral changes relayed to the catalytic center.

Hiraga K, Soga I, Dansereau JT, Pereira B, Derbyshire V, Du Z, Wang C, Van Roey P, Belfort G, Belfort M.

J Mol Biol. 2009 Nov 13;393(5):1106-17. doi: 10.1016/j.jmb.2009.08.074. Epub 2009 Sep 8.

35.

Genomic organization of regions that regulate chicken glycine decarboxylase gene transcription: physiological and pathological implications.

Kawaguchi H, Okamoto S, Sikdar D, Kume A, Li F, Mohafez OM, Shehata MH, Hiraga K.

Gene. 2009 Mar 1;432(1-2):7-18. doi: 10.1016/j.gene.2008.11.014. Epub 2008 Nov 24.

PMID:
19084582
36.

Characterization of diabetic nephropathy in CaM kinase IIalpha (Thr286Asp) transgenic mice.

Suzuki H, Kato I, Usui I, Takasaki I, Tabuchi Y, Oya T, Tsuneyama K, Kawaguchi H, Hiraga K, Takasawa S, Okamoto H, Tobe K, Sasahara M.

Biochem Biophys Res Commun. 2009 Jan 30;379(1):38-42. doi: 10.1016/j.bbrc.2008.11.143. Epub 2008 Dec 12.

PMID:
19070598
37.

Kinetic analysis of salting activation of a subtilisin-like halophilic protease.

Okamoto DN, Kondo MY, Santos JA, Nakajima S, Hiraga K, Oda K, Juliano MA, Juliano L, Gouvea IE.

Biochim Biophys Acta. 2009 Feb;1794(2):367-73. doi: 10.1016/j.bbapap.2008.10.017. Epub 2008 Nov 12.

PMID:
19056523
38.

Glycine cleavage system: reaction mechanism, physiological significance, and hyperglycinemia.

Kikuchi G, Motokawa Y, Yoshida T, Hiraga K.

Proc Jpn Acad Ser B Phys Biol Sci. 2008;84(7):246-63. Review.

39.

Mutation-, aging-, and gene dosage-dependent accumulation of neuroserpin (G392E) in endoplasmic reticula and lysosomes of neurons in transgenic mice.

Takasawa A, Kato I, Takasawa K, Ishii Y, Yoshida T, Shehata MH, Kawaguchi H, Mohafez OM, Sasahara M, Hiraga K.

J Biol Chem. 2008 Dec 19;283(51):35606-13. doi: 10.1074/jbc.M804125200. Epub 2008 Oct 21.

40.

Nonalcoholic steatohepatitis and hepatocellular carcinoma in galectin-3 knockout mice.

Nakanishi Y, Tsuneyama K, Nomoto K, Fujimoto M, Salunga TL, Nakajima T, Miwa S, Murai Y, Hayashi S, Kato I, Hiraga K, Hsu DK, Liu FT, Takano Y.

Hepatol Res. 2008 Dec;38(12):1241-51. doi: 10.1111/j.1872-034X.2008.00395.x. Epub 2008 Jul 4.

PMID:
18637146
41.

Lactobacillus senmaizukei sp. nov., isolated from Japanese pickle.

Hiraga K, Ueno Y, Sukontasing S, Tanasupawat S, Oda K.

Int J Syst Evol Microbiol. 2008 Jul;58(Pt 7):1625-9. doi: 10.1099/ijs.0.65677-0.

PMID:
18599706
42.

A novel model of insulin-dependent diabetes with renal and retinal lesions by transgenic expression of CaMKIIalpha (Thr286Asp) in pancreatic beta-cells.

Kato I, Oya T, Suzuki H, Takasawa K, Ichsan AM, Nakada S, Ishii Y, Shimada Y, Sasahara M, Tobe K, Takasawa S, Okamoto H, Hiraga K.

Diabetes Metab Res Rev. 2008 Sep;24(6):486-97. doi: 10.1002/dmrr.864.

PMID:
18551708
43.

Glutamate decarboxylase from Lactobacillus brevis: activation by ammonium sulfate.

Hiraga K, Ueno Y, Oda K.

Biosci Biotechnol Biochem. 2008 May;72(5):1299-306. Epub 2008 May 7.

44.

Combinatorial recombination of gene fragments to construct a library of chimeras.

Meyer MM, Hiraga K, Arnold FH.

Curr Protoc Protein Sci. 2006 Jun;Chapter 26:Unit 26.2. doi: 10.1002/0471140864.ps2602s44.

PMID:
18429308
45.

Novel transcript profiling of diffuse alveolar damage induced by hyperoxia exposure in mice: normalization by glyceraldehyde 3-phosphate dehydrogenase.

Shimada I, Matsui K, Brinkmann B, Hohoff C, Hiraga K, Tabuchi Y, Takasaki I, Kato I, Kawaguchi H, Takasawa K, Iida R, Takizawa H, Matsuki T.

Int J Legal Med. 2008 Sep;122(5):373-83. doi: 10.1007/s00414-008-0226-6. Epub 2008 Feb 27.

PMID:
18301909
46.

Targeted disruption of the galectin-3 gene results in decreased susceptibility to NNK-induced lung tumorigenesis: an oligonucleotide microarray study.

Abdel-Aziz HO, Murai Y, Takasaki I, Tabuchi Y, Zheng HC, Nomoto K, Takahashi H, Tsuneyama K, Kato I, Hsu DK, Liu FT, Hiraga K, Takano Y.

J Cancer Res Clin Oncol. 2008 Jul;134(7):777-88. doi: 10.1007/s00432-007-0345-3. Epub 2008 Jan 17.

PMID:
18204863
47.

Source analysis of the magnetic field evoked during self-paced finger movements.

Niimi M, Ohira T, Akiyama T, Hiraga K, Kaneko Y, Ochiai M, Fukunaga A, Kobayashi M, Kawase T.

Neurol Res. 2008 Apr;30(3):239-43. Epub 2007 Sep 10.

PMID:
17848207
48.

Barriers to providing palliative care and priorities for future actions to advance palliative care in Japan: a nationwide expert opinion survey.

Miyashita M, Sanjo M, Morita T, Hirai K, Kizawa Y, Shima Y, Shimoyama N, Tsuneto S, Hiraga K, Sato K, Uchitomi Y.

J Palliat Med. 2007 Apr;10(2):390-9.

PMID:
17472511
49.

Preparation and observation of fresh-frozen sections of the green fluorescent protein transgenic mouse head.

Tada M, Shinohara Y, Kato I, Hiraga K, Aizawa T, Demura M, Mori Y, Shinoda H, Mizuguchi M, Kawano K.

Acta Histochem Cytochem. 2006 Apr 22;39(2):31-4. Epub 2006 Mar 29.

50.

Neuroprotective role of transgenic PAF-acetylhydrolase II in mouse models of focal cerebral ischemia.

Umemura K, Kato I, Hirashima Y, Ishii Y, Inoue T, Aoki J, Kono N, Oya T, Hayashi N, Hamada H, Endo S, Oda M, Arai H, Kinouchi H, Hiraga K.

Stroke. 2007 Mar;38(3):1063-8. Epub 2007 Feb 1.

PMID:
17272759

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