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Items: 46

1.

β-Catenin/TCF4 Complex-Mediated Induction of the NRF3 (NFE2L3) Gene in Cancer Cells.

Aono S, Hatanaka A, Hatanaka A, Gao Y, Hippo Y, Taketo MM, Waku T, Kobayashi A.

Int J Mol Sci. 2019 Jul 8;20(13). pii: E3344. doi: 10.3390/ijms20133344.

2.

Establishment and characterization of patient-derived organoids from a young patient with cervical clear cell carcinoma.

Maru Y, Tanaka N, Ebisawa K, Odaka A, Sugiyama T, Itami M, Hippo Y.

Cancer Sci. 2019 Sep;110(9):2992-3005. doi: 10.1111/cas.14119. Epub 2019 Jul 23.

3.

Organoid-based ex vivo reconstitution of Kras-driven pancreatic ductal carcinogenesis.

Matsuura T, Maru Y, Izumiya M, Hoshi D, Kato S, Ochiai M, Hori M, Yamamoto S, Tatsuno K, Imai T, Aburatani H, Nakajima A, Hippo Y.

Carcinogenesis. 2019 Jun 22. pii: bgz122. doi: 10.1093/carcin/bgz122. [Epub ahead of print]

PMID:
31233118
4.

Current Status of Patient-Derived Ovarian Cancer Models.

Maru Y, Hippo Y.

Cells. 2019 May 25;8(5). pii: E505. doi: 10.3390/cells8050505. Review.

5.

Efficient use of patient-derived organoids as a preclinical model for gynecologic tumors.

Maru Y, Tanaka N, Itami M, Hippo Y.

Gynecol Oncol. 2019 Jul;154(1):189-198. doi: 10.1016/j.ygyno.2019.05.005. Epub 2019 May 14.

PMID:
31101504
6.

Kras-driven heterotopic tumor development from hepatobiliary organoids.

Ochiai M, Yoshihara Y, Maru Y, Tetsuya M, Izumiya M, Imai T, Hippo Y.

Carcinogenesis. 2019 Feb 7. doi: 10.1093/carcin/bgz024. [Epub ahead of print]

PMID:
30753336
7.

Shortcuts to intestinal carcinogenesis by genetic engineering in organoids.

Maru Y, Onuma K, Ochiai M, Imai T, Hippo Y.

Cancer Sci. 2019 Mar;110(3):858-866. doi: 10.1111/cas.13938. Epub 2019 Feb 3. Review.

8.

Hepatocyte growth factor activator inhibitor-2 stabilizes Epcam and maintains epithelial organization in the mouse intestine.

Kawaguchi M, Yamamoto K, Takeda N, Fukushima T, Yamashita F, Sato K, Kitamura K, Hippo Y, Janetka JW, Kataoka H.

Commun Biol. 2019 Jan 4;2:11. doi: 10.1038/s42003-018-0255-8. eCollection 2019.

9.

Ex vivo model of non-small cell lung cancer using mouse lung epithelial cells.

Sato T, Morita M, Tanaka R, Inoue Y, Nomura M, Sakamoto Y, Miura K, Ito S, Sato I, Tanaka N, Abe J, Takahashi S, Kawai M, Sato M, Hippo Y, Shima H, Okada Y, Tanuma N.

Oncol Lett. 2017 Dec;14(6):6863-6868. doi: 10.3892/ol.2017.7098. Epub 2017 Sep 28.

10.

Stemness Is Enhanced in Gastric Cancer by a SET/PP2A/E2F1 Axis.

Enjoji S, Yabe R, Tsuji S, Yoshimura K, Kawasaki H, Sakurai M, Sakai Y, Takenouchi H, Yoshino S, Hazama S, Nagano H, Oshima H, Oshima M, Vitek MP, Matsuura T, Hippo Y, Usui T, Ohama T, Sato K.

Mol Cancer Res. 2018 Mar;16(3):554-563. doi: 10.1158/1541-7786.MCR-17-0393. Epub 2018 Jan 12.

11.

Cilostazol and enzymatically modified isoquercitrin attenuate experimental colitis and colon cancer in mice by inhibiting cell proliferation and inflammation.

Kangawa Y, Yoshida T, Maruyama K, Okamoto M, Kihara T, Nakamura M, Ochiai M, Hippo Y, Hayashi SM, Shibutani M.

Food Chem Toxicol. 2017 Feb;100:103-114. doi: 10.1016/j.fct.2016.12.018. Epub 2016 Dec 15.

PMID:
27989839
12.

Identification of novel mutations in Japanese ovarian clear cell carcinoma patients using optimized targeted NGS for clinical diagnosis.

Maru Y, Tanaka N, Ohira M, Itami M, Hippo Y, Nagase H.

Gynecol Oncol. 2017 Feb;144(2):377-383. doi: 10.1016/j.ygyno.2016.11.045. Epub 2016 Dec 9.

PMID:
27939411
13.

Lentivirus-Based Stable Gene Delivery into Intestinal Organoids.

Maru Y, Orihashi K, Hippo Y.

Methods Mol Biol. 2016;1422:13-21. doi: 10.1007/978-1-4939-3603-8_2.

PMID:
27246018
14.

Non-neuronal acetylcholine as an endogenous regulator of proliferation and differentiation of Lgr5-positive stem cells in mice.

Takahashi T, Ohnishi H, Sugiura Y, Honda K, Suematsu M, Kawasaki T, Deguchi T, Fujii T, Orihashi K, Hippo Y, Watanabe T, Yamagaki T, Yuba S.

FEBS J. 2014 Oct;281(20):4672-90. doi: 10.1111/febs.12974. Epub 2014 Sep 13.

15.

Conditional knockout of the leptin receptor in the colonic epithelium revealed the local effects of leptin receptor signaling in the progression of colonic tumors in mice.

Higurashi T, Endo H, Uchiyama T, Uchiyama S, Yamada E, Ohkubo H, Sakai E, Takahashi H, Maeda S, Wada K, Natsumeda Y, Hippo Y, Nakajima A, Nakagama H.

Carcinogenesis. 2014 Sep;35(9):2134-41. doi: 10.1093/carcin/bgu135. Epub 2014 Jun 23.

PMID:
24958593
16.

Newly defined aberrant crypt foci as a marker for dysplasia in the rat colon.

Ochiai M, Hippo Y, Izumiya M, Watanabe M, Nakagama H.

Cancer Sci. 2014 Aug;105(8):943-50. doi: 10.1111/cas.12446. Epub 2014 Jul 12.

17.

AKT is critically involved in cooperation between obesity and the dietary carcinogen amino-1-methyl-6-phenylimidazo [4,5-b] (PhIP) toward colon carcinogenesis in rats.

Igarashi M, Hippo Y, Ochiai M, Fukuda H, Nakagama H.

Biochem Biophys Res Commun. 2014 Jan 17;443(3):852-7. doi: 10.1016/j.bbrc.2013.12.059. Epub 2013 Dec 14.

PMID:
24342614
18.

Genetic reconstitution of tumorigenesis in primary intestinal cells.

Onuma K, Ochiai M, Orihashi K, Takahashi M, Imai T, Nakagama H, Hippo Y.

Proc Natl Acad Sci U S A. 2013 Jul 2;110(27):11127-32. doi: 10.1073/pnas.1221926110. Epub 2013 Jun 17.

19.

The H19 induction triggers trophoblast lineage commitment in mouse ES cells.

Fujimori H, Mukai H, Murakami Y, Hemberger M, Hippo Y, Masutani M.

Biochem Biophys Res Commun. 2013 Jun 28;436(2):313-8. doi: 10.1016/j.bbrc.2013.05.100. Epub 2013 Jun 4.

PMID:
23743205
20.

Increased tumor necrosis factor receptor 1 expression in human colorectal adenomas.

Hosono K, Yamada E, Endo H, Takahashi H, Inamori M, Hippo Y, Nakagama H, Nakajima A.

World J Gastroenterol. 2012 Oct 14;18(38):5360-8. doi: 10.3748/wjg.v18.i38.5360.

21.

Number of aberrant crypt foci in the rectum is a useful surrogate marker of colorectal adenoma recurrence.

Uchiyama T, Takahashi H, Endo H, Kato S, Sakai E, Hosono K, Yoneda M, Inamori M, Hippo Y, Nakagama H, Nakajima A.

Dig Endosc. 2012 Sep;24(5):353-7. doi: 10.1111/j.1443-1661.2012.01289.x. Epub 2012 Apr 2.

PMID:
22925289
22.

Targeting synthetic lethal interactions between Myc and the eIF4F complex impedes tumorigenesis.

Lin CJ, Nasr Z, Premsrirut PK, Porco JA Jr, Hippo Y, Lowe SW, Pelletier J.

Cell Rep. 2012 Apr 19;1(4):325-33.

23.

Onset of quiescence following p53 mediated down-regulation of H2AX in normal cells.

Atsumi Y, Fujimori H, Fukuda H, Inase A, Shinohe K, Yoshioka Y, Shikanai M, Ichijima Y, Unno J, Mizutani S, Tsuchiya N, Hippo Y, Nakagama H, Masutani M, Teraoka H, Yoshioka K.

PLoS One. 2011;6(8):e23432. doi: 10.1371/journal.pone.0023432. Epub 2011 Aug 12.

24.

[Metabolic syndrome and carcinogenesis].

Hippo Y, Nakagama H.

Nihon Rinsho. 2011 Jan;69 Suppl 1:438-43. Review. Japanese. No abstract available.

PMID:
21766638
25.

Role of the long form leptin receptor and of the STAT3 signaling pathway in colorectal cancer progression.

Uchiyama T, Takahashi H, Endo H, Sugiyama M, Sakai E, Hosono K, Nagashima Y, Inayama Y, Wada K, Hippo Y, Nakajima A.

Int J Oncol. 2011 Oct;39(4):935-40. doi: 10.3892/ijo.2011.1105. Epub 2011 Jun 29.

PMID:
21720710
26.

The splicing-factor oncoprotein SF2/ASF activates mTORC1.

Karni R, Hippo Y, Lowe SW, Krainer AR.

Proc Natl Acad Sci U S A. 2008 Oct 7;105(40):15323-7. doi: 10.1073/pnas.0801376105. Epub 2008 Oct 1.

27.

mTORC1 promotes survival through translational control of Mcl-1.

Mills JR, Hippo Y, Robert F, Chen SM, Malina A, Lin CJ, Trojahn U, Wendel HG, Charest A, Bronson RT, Kogan SC, Nadon R, Housman DE, Lowe SW, Pelletier J.

Proc Natl Acad Sci U S A. 2008 Aug 5;105(31):10853-8. doi: 10.1073/pnas.0804821105. Epub 2008 Jul 29.

28.

Identification of ROBO1 as a novel hepatocellular carcinoma antigen and a potential therapeutic and diagnostic target.

Ito H, Funahashi S, Yamauchi N, Shibahara J, Midorikawa Y, Kawai S, Kinoshita Y, Watanabe A, Hippo Y, Ohtomo T, Iwanari H, Nakajima A, Makuuchi M, Fukayama M, Hirata Y, Hamakubo T, Kodama T, Tsuchiya M, Aburatani H.

Clin Cancer Res. 2006 Jun 1;12(11 Pt 1):3257-64.

29.

Dysregulated expression of P1 and P2 promoter-driven hepatocyte nuclear factor-4alpha in the pathogenesis of human cancer.

Tanaka T, Jiang S, Hotta H, Takano K, Iwanari H, Sumi K, Daigo K, Ohashi R, Sugai M, Ikegame C, Umezu H, Hirayama Y, Midorikawa Y, Hippo Y, Watanabe A, Uchiyama Y, Hasegawa G, Reid P, Aburatani H, Hamakubo T, Sakai J, Naito M, Kodama T.

J Pathol. 2006 Apr;208(5):662-72.

PMID:
16400631
30.

The glypican 3 oncofetal protein is a promising diagnostic marker for hepatocellular carcinoma.

Yamauchi N, Watanabe A, Hishinuma M, Ohashi K, Midorikawa Y, Morishita Y, Niki T, Shibahara J, Mori M, Makuuchi M, Hippo Y, Kodama T, Iwanari H, Aburatani H, Fukayama M.

Mod Pathol. 2005 Dec;18(12):1591-8.

31.

Overexpression of MUC13 is associated with intestinal-type gastric cancer.

Shimamura T, Ito H, Shibahara J, Watanabe A, Hippo Y, Taniguchi H, Chen Y, Kashima T, Ohtomo T, Tanioka F, Iwanari H, Kodama T, Kazui T, Sugimura H, Fukayama M, Aburatani H.

Cancer Sci. 2005 May;96(5):265-73.

32.

Overexpression of the aldo-keto reductase family protein AKR1B10 is highly correlated with smokers' non-small cell lung carcinomas.

Fukumoto S, Yamauchi N, Moriguchi H, Hippo Y, Watanabe A, Shibahara J, Taniguchi H, Ishikawa S, Ito H, Yamamoto S, Iwanari H, Hironaka M, Ishikawa Y, Niki T, Sohara Y, Kodama T, Nishimura M, Fukayama M, Dosaka-Akita H, Aburatani H.

Clin Cancer Res. 2005 Mar 1;11(5):1776-85.

33.

Identification of soluble NH2-terminal fragment of glypican-3 as a serological marker for early-stage hepatocellular carcinoma.

Hippo Y, Watanabe K, Watanabe A, Midorikawa Y, Yamamoto S, Ihara S, Tokita S, Iwanari H, Ito Y, Nakano K, Nezu J, Tsunoda H, Yoshino T, Ohizumi I, Tsuchiya M, Ohnishi S, Makuuchi M, Hamakubo T, Kodama T, Aburatani H.

Cancer Res. 2004 Apr 1;64(7):2418-23.

34.

An opposing view on WWOX protein function as a tumor suppressor.

Watanabe A, Hippo Y, Taniguchi H, Iwanari H, Yashiro M, Hirakawa K, Kodama T, Aburatani H.

Cancer Res. 2003 Dec 15;63(24):8629-33.

35.

Characterization of the mouse Abcc12 gene and its transcript encoding an ATP-binding cassette transporter, an orthologue of human ABCC12.

Shimizu H, Taniguchi H, Hippo Y, Hayashizaki Y, Aburatani H, Ishikawa T.

Gene. 2003 May 22;310:17-28.

PMID:
12801629
36.

Interleukin-1beta expression in human gastric carcinoma with Epstein-Barr virus infection.

Chong JM, Sakuma K, Sudo M, Osawa T, Ohara E, Uozaki H, Shibahara J, Kuroiwa K, Tominaga S, Hippo Y, Aburatani H, Funata N, Fukayama M.

J Virol. 2002 Jul;76(13):6825-31.

37.

Global gene expression analysis of gastric cancer by oligonucleotide microarrays.

Hippo Y, Taniguchi H, Tsutsumi S, Machida N, Chong JM, Fukayama M, Kodama T, Aburatani H.

Cancer Res. 2002 Jan 1;62(1):233-40.

38.

[Transcatheter arterial chemoembolization using autologous blood clot for the treatment of hepatocellular carcinoma: long-term results of treatment and prognostic factors].

Watanabe K, Hippo Y, Kanamori H, Gunji T, Ohnishi S, Akahane M, Ohtomo K, Kawauchi N.

Nihon Rinsho. 2001 Oct;59 Suppl 6:528-33. Review. Japanese. No abstract available.

PMID:
11762006
39.

Differential gene expression profiles of scirrhous gastric cancer cells with high metastatic potential to peritoneum or lymph nodes.

Hippo Y, Yashiro M, Ishii M, Taniguchi H, Tsutsumi S, Hirakawa K, Kodama T, Aburatani H.

Cancer Res. 2001 Feb 1;61(3):889-95.

40.

Polymyositis as a paraneoplastic manifestation of hepatocellular carcinoma.

Hasegawa K, Uesugi H, Kubota K, Ugawa Y, Murayama S, Kobayashi T, Hippo Y, Gunji T, Ohnishi S, Mori M, Makuuchi M.

Hepatogastroenterology. 2000 Sep-Oct;47(35):1425-7.

PMID:
11100367
41.

Structure and chromosome location of human OGG1.

Ishida T, Hippo Y, Nakahori Y, Matsushita I, Kodama T, Nishimura S, Aburatani H.

Cytogenet Cell Genet. 1999;85(3-4):232-6.

PMID:
10449904
42.

New DNA polymorphisms of human MMH/OGG1 gene: prevalence of one polymorphism among lung-adenocarcinoma patients in Japanese.

Ishida T, Takashima R, Fukayama M, Hamada C, Hippo Y, Fujii T, Moriyama S, Matsuba C, Nakahori Y, Morita H, Yazaki Y, Kodama T, Nishimura S, Aburatani H.

Int J Cancer. 1999 Jan 5;80(1):18-21.

43.

[A case of severe drug-induced peliosis hepatis with radiologically confirmed healing].

Gunji T, Ohnishi S, Hippo Y, Miura H, Aburatani H, Ohtomo K, Kitamura K, Yazaki Y.

Nihon Shokakibyo Gakkai Zasshi. 1998 Dec;95(12):1378-81. Japanese. No abstract available.

PMID:
9889548
44.

Representational difference analysis and loss of heterozygosity studies detect 3p deletions in neuroblastoma.

Hallstensson K, Thulin S, Aburatani H, Hippo Y, Martinsson T.

Eur J Cancer. 1997 Oct;33(12):1966-70.

PMID:
9516834
45.

Cloning and characterization of mammalian 8-hydroxyguanine-specific DNA glycosylase/apurinic, apyrimidinic lyase, a functional mutM homologue.

Aburatani H, Hippo Y, Ishida T, Takashima R, Matsuba C, Kodama T, Takao M, Yasui A, Yamamoto K, Asano M.

Cancer Res. 1997 Jun 1;57(11):2151-6.

46.

[Esophagobronchial fistula and empyema resulting from esophageal carcinoma].

Hippo Y, Kawana A, Yoshizawa A, Koshino T, Toyota E, Kobayashi N, Kobori O, Arai T, Kudo K, Kabe J.

Nihon Kyobu Shikkan Gakkai Zasshi. 1997 May;35(5):583-7. Japanese.

PMID:
9234640

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