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Items: 1 to 50 of 273

1.

Influence of Casein kinase II inhibitor CX-4945 on BCL6-mediated apoptotic signaling in B-ALL in vitro and in vivo.

Richter A, Sender S, Lenz A, Schwarz R, Hinz B, Knuebel G, Sekora A, Murua Escobar H, Junghanss C, Roolf C.

BMC Cancer. 2020 Mar 4;20(1):184. doi: 10.1186/s12885-020-6650-9.

2.

The circadian clock protein REVERBα inhibits pulmonary fibrosis development.

Cunningham PS, Meijer P, Nazgiewicz A, Anderson SG, Borthwick LA, Bagnall J, Kitchen GB, Lodyga M, Begley N, Venkateswaran RV, Shah R, Mercer PF, Durrington HJ, Henderson NC, Piper-Hanley K, Fisher AJ, Chambers RC, Bechtold DA, Gibbs JE, Loudon AS, Rutter MK, Hinz B, Ray DW, Blaikley JF.

Proc Natl Acad Sci U S A. 2020 Jan 14;117(2):1139-1147. doi: 10.1073/pnas.1912109117. Epub 2019 Dec 26.

3.

TGF-β1 - A truly transforming growth factor in fibrosis and immunity.

Lodyga M, Hinz B.

Semin Cell Dev Biol. 2019 Dec 23. pii: S1084-9521(18)30278-7. doi: 10.1016/j.semcdb.2019.12.010. [Epub ahead of print] Review.

PMID:
31879265
4.

Dancing with the Cells: Acoustic Microflows Generated by Oscillating Cells.

Salari A, Appak-Baskoy S, Ezzo M, Hinz B, Kolios MC, Tsai SSH.

Small. 2020 Mar;16(9):e1903788. doi: 10.1002/smll.201903788. Epub 2019 Dec 12.

PMID:
31829522
5.

Evasion of apoptosis by myofibroblasts: a hallmark of fibrotic diseases.

Hinz B, Lagares D.

Nat Rev Rheumatol. 2020 Jan;16(1):11-31. doi: 10.1038/s41584-019-0324-5. Epub 2019 Dec 2. Review.

PMID:
31792399
6.

A novel method for engineering autologous non-thrombogenic in situ tissue-engineered blood vessels for arteriovenous grafting.

Geelhoed WJ, van der Bogt KEA, Rothuizen TC, Damanik FFR, Hamming JF, Mota CD, van Agen MS, de Boer HC, Restrepo MT, Hinz B, Kislaya A, Poelma C, van Zonneveld AJ, Rabelink TJ, Moroni L, Rotmans JI.

Biomaterials. 2020 Jan;229:119577. doi: 10.1016/j.biomaterials.2019.119577. Epub 2019 Oct 29.

PMID:
31704466
7.

Interaction of Pregnancy-Specific Glycoprotein 1 With Integrin Α5β1 Is a Modulator of Extravillous Trophoblast Functions.

Rattila S, Dunk CEE, Im M, Grichenko O, Zhou Y, Yanez-Mo M, Blois SM, Yamada KM, Erez O, Gomez-Lopez N, Lye SJ, Hinz B, Romero R, Cohen M, Dveksler G.

Cells. 2019 Oct 31;8(11). pii: E1369. doi: 10.3390/cells8111369.

8.

Tracking adiponectin biodistribution via fluorescence molecular tomography indicates increased vascular permeability after streptozotocin-induced diabetes.

Yoon N, Dadson K, Dang T, Chu T, Noskovicova N, Hinz B, Raignault A, Thorin E, Kim S, Jeon JS, Jonkman J, McKee TD, Grant J, Peterson JD, Kelly SP, Sweeney G.

Am J Physiol Endocrinol Metab. 2019 Nov 1;317(5):E760-E772. doi: 10.1152/ajpendo.00564.2018. Epub 2019 Jul 16.

PMID:
31310580
9.

Modulation of the Endocannabinoid System as a Potential Anticancer Strategy.

Ramer R, Schwarz R, Hinz B.

Front Pharmacol. 2019 May 9;10:430. doi: 10.3389/fphar.2019.00430. eCollection 2019. Review.

10.

Author Correction: Dynamic fibroblast contractions attract remote macrophages in fibrillar collagen matrix.

Pakshir P, Alizadehgiashi M, Wong B, Coelho NM, Chen X, Gong Z, Shenoy VB, McCulloch CA, Hinz B.

Nat Commun. 2019 May 20;10(1):2286. doi: 10.1038/s41467-019-10344-4.

11.

Dynamic fibroblast contractions attract remote macrophages in fibrillar collagen matrix.

Pakshir P, Alizadehgiashi M, Wong B, Coelho NM, Chen X, Gong Z, Shenoy VB, McCulloch CA, Hinz B.

Nat Commun. 2019 Apr 23;10(1):1850. doi: 10.1038/s41467-019-09709-6. Erratum in: Nat Commun. 2019 May 20;10(1):2286.

12.

Fascia Is Able to Actively Contract and May Thereby Influence Musculoskeletal Dynamics: A Histochemical and Mechanographic Investigation.

Schleip R, Gabbiani G, Wilke J, Naylor I, Hinz B, Zorn A, Jäger H, Breul R, Schreiner S, Klingler W.

Front Physiol. 2019 Apr 2;10:336. doi: 10.3389/fphys.2019.00336. eCollection 2019.

13.

Mechanical regulation of myofibroblast phenoconversion and collagen contraction.

Hinz B, McCulloch CA, Coelho NM.

Exp Cell Res. 2019 Jun 1;379(1):119-128. doi: 10.1016/j.yexcr.2019.03.027. Epub 2019 Mar 22. Review.

PMID:
30910400
14.

Cadherin-11-mediated adhesion of macrophages to myofibroblasts establishes a profibrotic niche of active TGF-β.

Lodyga M, Cambridge E, Karvonen HM, Pakshir P, Wu B, Boo S, Kiebalo M, Kaarteenaho R, Glogauer M, Kapoor M, Ask K, Hinz B.

Sci Signal. 2019 Jan 15;12(564). pii: eaao3469. doi: 10.1126/scisignal.aao3469.

PMID:
30647145
15.

Activation of latent transforming growth factor-β1, a conserved function for pregnancy-specific beta 1-glycoproteins.

Warren J, Im M, Ballesteros A, Ha C, Moore T, Lambert F, Lucas S, Hinz B, Dveksler G.

Mol Hum Reprod. 2018 Dec 1;24(12):602-612. doi: 10.1093/molehr/gay044.

16.

Up-regulation of heme oxygenase-1 expression and inhibition of disease-associated features by cannabidiol in vascular smooth muscle cells.

Schwartz M, Böckmann S, Hinz B.

Oncotarget. 2018 Oct 2;9(77):34595-34616. doi: 10.18632/oncotarget.26191. eCollection 2018 Oct 2.

17.

The antiangiogenic action of cisplatin on endothelial cells is mediated through the release of tissue inhibitor of matrix metalloproteinases-1 from lung cancer cells.

Ramer R, Schmied T, Wagner C, Haustein M, Hinz B.

Oncotarget. 2018 Sep 25;9(75):34038-34055. doi: 10.18632/oncotarget.25954. eCollection 2018 Sep 25.

18.

Novel differences in gene expression and functional capabilities of myofibroblast populations in idiopathic pulmonary fibrosis.

Walsh SM, Worrell JC, Fabre A, Hinz B, Kane R, Keane MP.

Am J Physiol Lung Cell Mol Physiol. 2018 Nov 1;315(5):L697-L710. doi: 10.1152/ajplung.00543.2017. Epub 2018 Aug 9.

19.

Anti-tumour actions of cannabinoids.

Hinz B, Ramer R.

Br J Pharmacol. 2019 May;176(10):1384-1394. doi: 10.1111/bph.14426. Epub 2018 Aug 7. Review.

PMID:
30019449
20.

Fibrotic microtissue array to predict anti-fibrosis drug efficacy.

Asmani M, Velumani S, Li Y, Wawrzyniak N, Hsia I, Chen Z, Hinz B, Zhao R.

Nat Commun. 2018 May 25;9(1):2066. doi: 10.1038/s41467-018-04336-z.

21.

SB202190 inhibits endothelial cell apoptosis via induction of autophagy and heme oxygenase-1.

Schwartz M, Böckmann S, Borchert P, Hinz B.

Oncotarget. 2018 May 1;9(33):23149-23163. doi: 10.18632/oncotarget.25234. eCollection 2018 May 1.

22.

Experimental Right Ventricular Hypertension Induces Regional β1-Integrin-Mediated Transduction of Hypertrophic and Profibrotic Right and Left Ventricular Signaling.

Sun M, Ishii R, Okumura K, Krauszman A, Breitling S, Gomez O, Hinek A, Boo S, Hinz B, Connelly KA, Kuebler WM, Friedberg MK.

J Am Heart Assoc. 2018 Mar 29;7(7). pii: e007928. doi: 10.1161/JAHA.117.007928.

23.

Therapeutic approaches to control tissue repair and fibrosis: Extracellular matrix as a game changer.

Walraven M, Hinz B.

Matrix Biol. 2018 Oct;71-72:205-224. doi: 10.1016/j.matbio.2018.02.020. Epub 2018 Feb 27. Review.

PMID:
29499355
24.

The big five in fibrosis: Macrophages, myofibroblasts, matrix, mechanics, and miscommunication.

Pakshir P, Hinz B.

Matrix Biol. 2018 Aug;68-69:81-93. doi: 10.1016/j.matbio.2018.01.019. Epub 2018 Jan 31. Review.

PMID:
29408013
25.

Targeting the endocannabinoid system as a potential anticancer approach.

Schwarz R, Ramer R, Hinz B.

Drug Metab Rev. 2018 Feb;50(1):26-53. doi: 10.1080/03602532.2018.1428344. Epub 2018 Feb 1. Review.

PMID:
29390896
26.

The fibronectin ED-A domain enhances recruitment of latent TGF-β-binding protein-1 to the fibroblast matrix.

Klingberg F, Chau G, Walraven M, Boo S, Koehler A, Chow ML, Olsen AL, Im M, Lodyga M, Wells RG, White ES, Hinz B.

J Cell Sci. 2018 Mar 1;131(5). pii: jcs201293. doi: 10.1242/jcs.201293.

27.

Decisive role of P42/44 mitogen-activated protein kinase in Δ9-tetrahydrocannabinol-induced migration of human mesenchymal stem cells.

Lüder E, Ramer R, Peters K, Hinz B.

Oncotarget. 2017 Nov 20;8(62):105984-105994. doi: 10.18632/oncotarget.22517. eCollection 2017 Dec 1.

28.

Activin A in Inflammation, Tissue Repair, and Fibrosis: Possible Role as Inflammatory and Fibrotic Mediator of Uterine Fibroid Development and Growth.

Protic O, Islam MS, Greco S, Giannubilo SR, Lamanna P, Petraglia F, Ciavattini A, Castellucci M, Hinz B, Ciarmela P.

Semin Reprod Med. 2017 Nov;35(6):499-509. doi: 10.1055/s-0037-1607265. Epub 2017 Nov 3. Review. No abstract available.

PMID:
29100238
29.

Collagen scaffold enhances the regenerative properties of mesenchymal stromal cells.

Rashedi I, Talele N, Wang XH, Hinz B, Radisic M, Keating A.

PLoS One. 2017 Oct 31;12(10):e0187348. doi: 10.1371/journal.pone.0187348. eCollection 2017.

30.

Cannabinoids as Anticancer Drugs.

Ramer R, Hinz B.

Adv Pharmacol. 2017;80:397-436. doi: 10.1016/bs.apha.2017.04.002. Epub 2017 Jun 12. Review.

PMID:
28826542
31.

The FOXP2-Driven Network in Developmental Disorders and Neurodegeneration.

Oswald F, Klöble P, Ruland A, Rosenkranz D, Hinz B, Butter F, Ramljak S, Zechner U, Herlyn H.

Front Cell Neurosci. 2017 Jul 26;11:212. doi: 10.3389/fncel.2017.00212. eCollection 2017.

32.

Lipocalin-2 induces NLRP3 inflammasome activation via HMGB1 induced TLR4 signaling in heart tissue of mice under pressure overload challenge.

Song E, Jahng JW, Chong LP, Sung HK, Han M, Luo C, Wu D, Boo S, Hinz B, Cooper MA, Robertson AA, Berger T, Mak TW, George I, Schulze PC, Wang Y, Xu A, Sweeney G.

Am J Transl Res. 2017 Jun 15;9(6):2723-2735. eCollection 2017.

33.

Plasma fibronectin stabilizes Borrelia burgdorferi-endothelial interactions under vascular shear stress by a catch-bond mechanism.

Niddam AF, Ebady R, Bansal A, Koehler A, Hinz B, Moriarty TJ.

Proc Natl Acad Sci U S A. 2017 Apr 25;114(17):E3490-E3498. doi: 10.1073/pnas.1615007114. Epub 2017 Apr 10.

34.

Discoidin Domain Receptor 1 Mediates Myosin-Dependent Collagen Contraction.

Coelho NM, Arora PD, van Putten S, Boo S, Petrovic P, Lin AX, Hinz B, McCulloch CA.

Cell Rep. 2017 Feb 14;18(7):1774-1790. doi: 10.1016/j.celrep.2017.01.061.

35.

The role of myofibroblasts in wound healing.

Hinz B.

Curr Res Transl Med. 2016 Oct - Dec;64(4):171-177. doi: 10.1016/j.retram.2016.09.003. Epub 2016 Nov 4. Review.

PMID:
27939455
36.

Connecting (T)issues: How Research in Fascia Biology Can Impact Integrative Oncology.

Langevin HM, Keely P, Mao J, Hodge LM, Schleip R, Deng G, Hinz B, Swartz MA, de Valois BA, Zick S, Findley T.

Cancer Res. 2016 Nov 1;76(21):6159-6162. Epub 2016 Oct 11. Review.

37.

MicroRNA-21 preserves the fibrotic mechanical memory of mesenchymal stem cells.

Li CX, Talele NP, Boo S, Koehler A, Knee-Walden E, Balestrini JL, Speight P, Kapus A, Hinz B.

Nat Mater. 2017 Mar;16(3):379-389. doi: 10.1038/nmat4780. Epub 2016 Oct 31.

PMID:
27798620
38.

Crossing Into the Next Frontier of Cardiac Extracellular Matrix Research.

Spinale FG, Frangogiannis NG, Hinz B, Holmes JW, Kassiri Z, Lindsey ML.

Circ Res. 2016 Oct 28;119(10):1040-1045. No abstract available.

39.

Inhibition of interleukin-1β-induced endothelial tissue factor expression by the synthetic cannabinoid WIN 55,212-2.

Scholl A, Ivanov I, Hinz B.

Oncotarget. 2016 Sep 20;7(38):61438-61457. doi: 10.18632/oncotarget.11367.

40.

Does Breathing Amplify Fibrosis?

Hinz B, Suki B.

Am J Respir Crit Care Med. 2016 Jul 1;194(1):9-11. doi: 10.1164/rccm.201601-0149ED. No abstract available.

PMID:
27367884
41.

Strategies to overcome the hurdles to treat fibrosis, a major unmet clinical need.

Nanchahal J, Hinz B.

Proc Natl Acad Sci U S A. 2016 Jul 5;113(27):7291-3. doi: 10.1073/pnas.1607896113. Epub 2016 Jun 24. No abstract available.

42.

The myofibroblast in wound healing and fibrosis: answered and unanswered questions.

Bochaton-Piallat ML, Gabbiani G, Hinz B.

F1000Res. 2016 Apr 26;5. pii: F1000 Faculty Rev-752. doi: 10.12688/f1000research.8190.1. eCollection 2016. Review.

43.

Differential effects of endogenous, phyto and synthetic cannabinoids on thrombogenesis and platelet activity.

Grambow E, Strüder D, Klar E, Hinz B, Vollmar B.

Biofactors. 2016 Nov 12;42(6):581-590. doi: 10.1002/biof.1294. Epub 2016 May 6.

PMID:
27151562
44.

Cellular, structural and functional cardiac remodelling following pressure overload and unloading.

Dadson K, Kovacevic V, Rengasamy P, Kim GH, Boo S, Li RK, George I, Schulze PC, Hinz B, Sweeney G.

Int J Cardiol. 2016 Aug 1;216:32-42. doi: 10.1016/j.ijcard.2016.03.240. Epub 2016 Apr 23.

PMID:
27140334
45.

Antitumorigenic targets of cannabinoids - current status and implications.

Ramer R, Hinz B.

Expert Opin Ther Targets. 2016 Oct;20(10):1219-35. doi: 10.1080/14728222.2016.1177512. Epub 2016 May 11. Review.

PMID:
27070944
46.

YAP/TAZ Are Mechanoregulators of TGF-β-Smad Signaling and Renal Fibrogenesis.

Szeto SG, Narimatsu M, Lu M, He X, Sidiqi AM, Tolosa MF, Chan L, De Freitas K, Bialik JF, Majumder S, Boo S, Hinz B, Dan Q, Advani A, John R, Wrana JL, Kapus A, Yuen DA.

J Am Soc Nephrol. 2016 Oct;27(10):3117-3128. doi: 10.1681/ASN.2015050499. Epub 2016 Mar 9.

47.

Fatty acid amide hydrolase inhibitors confer anti-invasive and antimetastatic effects on lung cancer cells.

Winkler K, Ramer R, Dithmer S, Ivanov I, Merkord J, Hinz B.

Oncotarget. 2016 Mar 22;7(12):15047-64. doi: 10.18632/oncotarget.7592.

48.

Lovastatin lactone elicits human lung cancer cell apoptosis via a COX-2/PPARγ-dependent pathway.

Walther U, Emmrich K, Ramer R, Mittag N, Hinz B.

Oncotarget. 2016 Mar 1;7(9):10345-62. doi: 10.18632/oncotarget.7213.

49.

Integrins Form an Expanding Diffusional Barrier that Coordinates Phagocytosis.

Freeman SA, Goyette J, Furuya W, Woods EC, Bertozzi CR, Bergmeier W, Hinz B, van der Merwe PA, Das R, Grinstein S.

Cell. 2016 Jan 14;164(1-2):128-140. doi: 10.1016/j.cell.2015.11.048.

50.

Hic-5 is required for myofibroblast differentiation by regulating mechanically dependent MRTF-A nuclear accumulation.

Varney SD, Betts CB, Zheng R, Wu L, Hinz B, Zhou J, Van De Water L.

J Cell Sci. 2016 Feb 15;129(4):774-87. doi: 10.1242/jcs.170589. Epub 2016 Jan 12.

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