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Items: 7


The CD25-binding antibody Daclizumab High-Yield Process has a distinct glycosylation pattern and reduced antibody-dependent cell-mediated cytotoxicity in comparison to Zenapax®.

Ganguly B, Balasa B, Efros L, Hinton PR, Hartman S, Thakur A, Xiong JM, Schmidt B, Robinson RR, Sornasse T, Vexler V, Sheridan JP.

MAbs. 2016 Oct;8(7):1417-1424. Epub 2016 Jul 1.


The human G1m1 allotype associates with CD4+ T-cell responsiveness to a highly conserved IgG1 constant region peptide and confers an asparaginyl endopeptidase cleavage site.

Stickler MM, Reddy A, Xiong JM, Hinton PR, DuBridge R, Harding FA.

Genes Immun. 2011 Apr;12(3):213-21. doi: 10.1038/gene.2010.68. Epub 2011 Feb 17.


An engineered human IgG1 antibody with longer serum half-life.

Hinton PR, Xiong JM, Johlfs MG, Tang MT, Keller S, Tsurushita N.

J Immunol. 2006 Jan 1;176(1):346-56.


Design of humanized antibodies: from anti-Tac to Zenapax.

Tsurushita N, Hinton PR, Kumar S.

Methods. 2005 May;36(1):69-83.


Engineered human IgG antibodies with longer serum half-lives in primates.

Hinton PR, Johlfs MG, Xiong JM, Hanestad K, Ong KC, Bullock C, Keller S, Tang MT, Tso JY, Vásquez M, Tsurushita N.

J Biol Chem. 2004 Feb 20;279(8):6213-6. Epub 2003 Dec 29.


Properties and pharmacokinetics of two humanized antibodies specific for L-selectin.

Co MS, Landolfi NF, Nagy JO, Tan JH, Vexler V, Vasquez M, Roark L, Yuan S, Hinton PR, Melrose J, Klingbeil C, Queen C, Berg EL.

Immunotechnology. 1999 Mar;4(3-4):253-66.


LIMS and chromatographic data acquisition in the manufacturing environment.

Hinton MD, Hinton PR.

J Automat Chem. 1996;18(5):169-74. No abstract available.

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