Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 292

1.

Stromal fibroblasts induce metastatic tumor cell clusters via epithelial-mesenchymal plasticity.

Matsumura Y, Ito Y, Mezawa Y, Sulidan K, Daigo Y, Hiraga T, Mogushi K, Wali N, Suzuki H, Itoh T, Miyagi Y, Yokose T, Shimizu S, Takano A, Terao Y, Saeki H, Ozawa M, Abe M, Takeda S, Okumura K, Habu S, Hino O, Takeda K, Hamada M, Orimo A.

Life Sci Alliance. 2019 Jul 22;2(4). pii: e201900425. doi: 10.26508/lsa.201900425. Print 2019 Aug.

2.

Usefulness of immunohistochemistry for mismatch repair protein and microsatellite instability examination in adenocarcinoma and background endometrium of sporadic endometrial cancer cases.

Saeki H, Hlaing MT, Horimoto Y, Kajino K, Ohtsuji N, Fujino K, Terao Y, Hino O.

J Obstet Gynaecol Res. 2019 Jul 15. doi: 10.1111/jog.14061. [Epub ahead of print]

PMID:
31307113
3.

CD26 expression is attenuated by TGF-β and SDF-1 autocrine signaling on stromal myofibroblasts in human breast cancers.

Mezawa Y, Daigo Y, Takano A, Miyagi Y, Yokose T, Yamashita T, Morimoto C, Hino O, Orimo A.

Cancer Med. 2019 Jul;8(8):3936-3948. doi: 10.1002/cam4.2249. Epub 2019 May 29.

4.

In commemoration of the 2018 Mataro Nagayo Prize: A road to early diagnosis and monitoring of asbestos-related mesothelioma.

Hino O, Abe M, Han B, Yan Y.

Cancer Sci. 2019 May;110(5):1518-1524. doi: 10.1111/cas.14001. Epub 2019 Apr 8. Review.

5.

Renal medullary carcinoma in a young mixed-race man in Japan.

Toriyama A, Izumi H, Tomita S, Nagashima Y, Ueda Y, Aoki Y, Tsujimura A, Yao T, Hino O.

Pathol Int. 2019 Apr;69(4):241-245. doi: 10.1111/pin.12783. Epub 2019 Mar 7.

PMID:
30843648
6.

High-sensitivity Detection of Micrometastases Generated by GFP Lentivirus-transduced Organoids Cultured from a Patient-derived Colon Tumor.

Okazawa Y, Mizukoshi K, Koyama Y, Okubo S, Komiyama H, Kojima Y, Goto M, Habu S, Hino O, Sakamoto K, Orimo A.

J Vis Exp. 2018 Jun 14;(136). doi: 10.3791/57374.

PMID:
29985333
7.

Haploinsufficiency of the folliculin gene leads to impaired functions of lung fibroblasts in patients with Birt-Hogg-Dubé syndrome.

Hoshika Y, Takahashi F, Togo S, Hashimoto M, Nara T, Kobayashi T, Nurwidya F, Kataoka H, Kurihara M, Kobayashi E, Ebana H, Kikkawa M, Ando K, Nishino K, Hino O, Takahashi K, Seyama K.

Physiol Rep. 2016 Nov;4(21). pii: e13025. Epub 2016 Nov 15.

8.

Mourning Dr. Alfred G. Knudson: the two-hit hypothesis, tumor suppressor genes, and the tuberous sclerosis complex.

Hino O, Kobayashi T.

Cancer Sci. 2017 Jan;108(1):5-11. doi: 10.1111/cas.13116. Epub 2017 Jan 23. Review.

9.

Establishment of anti-mesothelioma monoclonal antibodies.

Mizutani N, Abe M, Matsuoka S, Kajino K, Wakiya M, Ohtsuji N, Hatano R, Morimoto C, Hino O.

BMC Res Notes. 2016 Jun 24;9:324. doi: 10.1186/s13104-016-2128-x.

10.

Clinical impacts of mesothelin expression in gastrointestinal carcinomas.

Einama T, Kawamata F, Kamachi H, Nishihara H, Homma S, Matsuzawa F, Mizukami T, Konishi Y, Tahara M, Kamiyama T, Hino O, Taketomi A, Todo S.

World J Gastrointest Pathophysiol. 2016 May 15;7(2):218-22. doi: 10.4291/wjgp.v7.i2.218. Review.

11.

Metabolic abnormalities induced by mitochondrial dysfunction in skeletal muscle of the renal carcinoma Eker (TSC2+/-) rat model.

Aizawa Y, Shirai T, Kobayashi T, Hino O, Tsujii Y, Inoue H, Kazami M, Tadokoro T, Suzuki T, Kobayashi K, Yamamoto Y.

Biosci Biotechnol Biochem. 2016 Aug;80(8):1513-9. doi: 10.1080/09168451.2016.1165603. Epub 2016 Mar 31.

PMID:
27031579
12.

Establishment of a Therapeutic Anti-Pan HLA-Class II Monoclonal Antibody That Directly Induces Lymphoma Cell Death via Large Pore Formation.

Matsuoka S, Ishii Y, Nakao A, Abe M, Ohtsuji N, Momose S, Jin H, Arase H, Sugimoto K, Nakauchi Y, Masutani H, Maeda M, Yagita H, Komatsu N, Hino O.

PLoS One. 2016 Mar 30;11(3):e0150496. doi: 10.1371/journal.pone.0150496. eCollection 2016.

13.

The tuberous sclerosis complex model Eker (TSC2+/-) rat exhibits hyperglycemia and hyperketonemia due to decreased glycolysis in the liver.

Aizawa Y, Shirai T, Kobayashi T, Hino O, Tsujii Y, Inoue H, Kazami M, Tadokoro T, Suzuki T, Kobayashi KI, Yamamoto Y.

Arch Biochem Biophys. 2016 Jan 15;590:48-55. doi: 10.1016/j.abb.2015.10.019. Epub 2015 Nov 6.

PMID:
26550928
14.

Aberrant differentiation of Tsc2-deficient teratomas associated with activation of the mTORC1-TFE3 pathway.

Kawano H, Ito Y, Kanai F, Nakamura E, Tada N, Takai S, Horie S, Kobayashi T, Hino O.

Oncol Rep. 2015 Nov;34(5):2251-8. doi: 10.3892/or.2015.4254. Epub 2015 Sep 8.

15.

Environmental carcinogenesis - 100th anniversary of creating cancer.

Imai M, Hino O.

Cancer Sci. 2015 Nov;106(11):1483-5. doi: 10.1111/cas.12798. Epub 2015 Oct 21. Review.

16.

Menstrual cycle could affect Ki67 expression in estrogen receptor-positive breast cancer patients.

Horimoto Y, Arakawa A, Tanabe M, Kuroda K, Matsuoka J, Igari F, Himuro T, Yoshida Y, Tokuda E, Shimizu H, Hino O, Saito M.

J Clin Pathol. 2015 Oct;68(10):825-9. doi: 10.1136/jclinpath-2015-203085. Epub 2015 Jun 9.

PMID:
26060263
17.

Rheb activation disrupts spine synapse formation through accumulation of syntenin in tuberous sclerosis complex.

Sugiura H, Yasuda S, Katsurabayashi S, Kawano H, Endo K, Takasaki K, Iwasaki K, Ichikawa M, Kobayashi T, Hino O, Yamagata K.

Nat Commun. 2015 Apr 16;6:6842. doi: 10.1038/ncomms7842.

PMID:
25880340
18.

Establishment of Tsc2‑deficient rat embryonic stem cells.

Ito Y, Kawano H, Kanai F, Nakamura E, Tada N, Takai S, Horie S, Arai H, Kobayashi T, Hino O.

Int J Oncol. 2015 May;46(5):1944-52. doi: 10.3892/ijo.2015.2913. Epub 2015 Mar 3.

PMID:
25738543
19.

Low FOXA1 expression predicts good response to neo-adjuvant chemotherapy resulting in good outcomes for luminal HER2-negative breast cancer cases.

Horimoto Y, Arakawa A, Harada-Shoji N, Sonoue H, Yoshida Y, Himuro T, Igari F, Tokuda E, Mamat O, Tanabe M, Hino O, Saito M.

Br J Cancer. 2015 Jan 20;112(2):345-51. doi: 10.1038/bjc.2014.595. Epub 2014 Nov 25.

20.

Rat N-ERC/mesothelin as a marker for in vivo screening of drugs against pancreas cancer.

Fukamachi K, Iigo M, Hagiwara Y, Shibata K, Futakuchi M, Alexander DB, Hino O, Suzui M, Tsuda H.

PLoS One. 2014 Oct 27;9(10):e111481. doi: 10.1371/journal.pone.0111481. eCollection 2014.

21.

Cotyledonoid dissecting leiomyoma of the uterus: report of two cases.

Saeki H, Suzuki C, Yamasaki S, Hashizume A, Izumi H, Suzuki F, Ishi K, Nojima M, Hino O.

Arch Gynecol Obstet. 2015 Feb;291(2):357-61. doi: 10.1007/s00404-014-3406-2. Epub 2014 Aug 13.

PMID:
25115281
22.

Transgenic expression of the N525S-tuberin variant in Tsc2 mutant (Eker) rats causes dominant embryonic lethality.

Shiono M, Kobayashi T, Takahashi R, Ueda M, Ishioka C, Hino O.

Sci Rep. 2014 Aug 4;4:5927. doi: 10.1038/srep05927.

23.

Newly established ELISA for N-ERC/mesothelin improves diagnostic accuracy in patients with suspected pleural mesothelioma.

Sato T, Suzuki Y, Mori T, Maeda M, Abe M, Hino O, Takahashi K.

Cancer Med. 2014 Oct;3(5):1377-84. doi: 10.1002/cam4.297. Epub 2014 Jul 10.

24.

Activation of Rheb, but not of mTORC1, impairs spine synapse morphogenesis in tuberous sclerosis complex.

Yasuda S, Sugiura H, Katsurabayashi S, Shimada T, Tanaka H, Takasaki K, Iwasaki K, Kobayashi T, Hino O, Yamagata K.

Sci Rep. 2014 Jun 3;4:5155. doi: 10.1038/srep05155.

25.

Retrospective analysis of large-scale research screening of construction workers for the early diagnosis of mesothelioma.

Hirohashi T, Igarashi K, Abe M, Maeda M, Hino O.

Mol Clin Oncol. 2014 Jan;2(1):26-30. Epub 2013 Oct 2.

26.

[Illustrated review on radiological diagnosis of occupational respiratory diseases].

Kusaka Y, Tamura T, Suganuma N, Shida H, Suzuki K, Satou T, Takahashi K, Hino O.

Nihon Rinsho. 2014 Feb;72(2):194-7. Review. Japanese. No abstract available.

PMID:
24605514
27.

Utility of PAX8 mouse monoclonal antibody in the diagnosis of thyroid, thymic, pleural and lung tumours: a comparison with polyclonal PAX8 antibody.

Toriyama A, Mori T, Sekine S, Yoshida A, Hino O, Tsuta K.

Histopathology. 2014 Oct;65(4):465-72. doi: 10.1111/his.12405. Epub 2014 Apr 26.

PMID:
24592933
28.

Elevated levels of serum fatty acid synthase in patients with gastric carcinoma.

Ito T, Sato K, Maekawa H, Sakurada M, Orita H, Shimada K, Daida H, Wada R, Abe M, Hino O, Kajiyama Y.

Oncol Lett. 2014 Mar;7(3):616-620. Epub 2014 Jan 14.

29.

AHNAK is highly expressed and plays a key role in cell migration and invasion in mesothelioma.

Sudo H, Tsuji AB, Sugyo A, Abe M, Hino O, Saga T.

Int J Oncol. 2014 Feb;44(2):530-8. doi: 10.3892/ijo.2013.2183. Epub 2013 Nov 20.

PMID:
24253341
30.

ERC/mesothelin is expressed in human gastric cancer tissues and cell lines.

Ito T, Kajino K, Abe M, Sato K, Maekawa H, Sakurada M, Orita H, Wada R, Kajiyama Y, Hino O.

Oncol Rep. 2014 Jan;31(1):27-33. doi: 10.3892/or.2013.2803. Epub 2013 Oct 22.

31.

Src plays a key role in ADAM28 expression in v-src-transformed epithelial cells and human carcinoma cells.

Abe H, Mochizuki S, Ohara K, Ueno M, Ochiai H, Kitagawa Y, Hino O, Sato H, Okada Y.

Am J Pathol. 2013 Nov;183(5):1667-1678. doi: 10.1016/j.ajpath.2013.07.011. Epub 2013 Sep 3.

PMID:
24007880
32.

Tuberin activates and controls the distribution of Rac1 via association with p62 and ubiquitin through the mTORC1 signaling pathway.

Okura H, Kobayashi T, Koike M, Ohsawa M, Zhang D, Arai H, Uchiyama Y, Hino O.

Int J Oncol. 2013 Aug;43(2):447-56. doi: 10.3892/ijo.2013.1984. Epub 2013 Jun 12.

PMID:
23759924
33.

Mesothelin expression is a prognostic factor in cholangiocellular carcinoma.

Nomura R, Fujii H, Abe M, Sugo H, Ishizaki Y, Kawasaki S, Hino O.

Int Surg. 2013 Apr-Jun;98(2):164-9. doi: 10.9738/INTSURG-D-13-00001.1.

34.

The N-ERC index is a novel monitoring and prognostic marker for advanced malignant pleural mesothelioma.

Mori T, Tajima K, Hirama M, Sato T, Kido K, Iwakami S, Sasaki S, Iwase A, Shiomi K, Maeda M, Hino O, Takahashi K.

J Thorac Dis. 2013 Apr;5(2):145-8. doi: 10.3978/j.issn.2072-1439.2013.03.03.

35.

Folliculin regulates cyclin D1 expression through cis-acting elements in the 3' untranslated region of cyclin D1 mRNA.

Kawai A, Kobayashi T, Hino O.

Int J Oncol. 2013 May;42(5):1597-604. doi: 10.3892/ijo.2013.1862. Epub 2013 Mar 21.

PMID:
23525507
36.

C-ERC/mesothelin provokes lymphatic invasion of colorectal adenocarcinoma.

Kawamata F, Homma S, Kamachi H, Einama T, Kato Y, Tsuda M, Tanaka S, Maeda M, Kajino K, Hino O, Takahashi N, Kamiyama T, Nishihara H, Taketomi A, Todo S.

J Gastroenterol. 2014 Jan;49(1):81-92. doi: 10.1007/s00535-013-0773-6. Epub 2013 Mar 20.

37.

Up-regulation of dbpA mRNA in hepatocellular carcinoma associated with metabolic syndrome.

Obulhasim G, Yasen M, Kajino K, Mogushi K, Tanaka S, Mizushima H, Tanaka H, Arii S, Hino O.

Hepatol Int. 2013 Mar;7(1):215-25. doi: 10.1007/s12072-012-9357-4. Epub 2012 Mar 13.

PMID:
26201636
38.

TSC1 controls distribution of actin fibers through its effect on function of Rho family of small GTPases and regulates cell migration and polarity.

Ohsawa M, Kobayashi T, Okura H, Igarashi T, Mizuguchi M, Hino O.

PLoS One. 2013;8(1):e54503. doi: 10.1371/journal.pone.0054503. Epub 2013 Jan 23.

39.

NP-1250, an ABCG2 inhibitor, induces apoptotic cell death in mitoxantrone-resistant breast carcinoma MCF7 cells via a caspase-independent pathway.

Ito M, Kajino K, Abe M, Fujimura T, Mineki R, Ikegami T, Ishikawa T, Hino O.

Oncol Rep. 2013 Apr;29(4):1492-500. doi: 10.3892/or.2013.2249. Epub 2013 Jan 24.

PMID:
23354844
40.

Rapamycin reverses impaired social interaction in mouse models of tuberous sclerosis complex.

Sato A, Kasai S, Kobayashi T, Takamatsu Y, Hino O, Ikeda K, Mizuguchi M.

Nat Commun. 2012;3:1292. doi: 10.1038/ncomms2295.

41.

The utility of serum N-ERC/mesothelin as a biomarker of ovarian carcinoma.

Saeki H, Hashizume A, Izumi H, Suzuki F, Ishi K, Nojima M, Maeda M, Hino O.

Oncol Lett. 2012 Oct;4(4):637-641. Epub 2012 Jul 11.

42.

Prevention of alveolar destruction and airspace enlargement in a mouse model of pulmonary lymphangioleiomyomatosis (LAM).

Goncharova EA, Goncharov DA, Fehrenbach M, Khavin I, Ducka B, Hino O, Colby TV, Merrilees MJ, Haczku A, Albelda SM, Krymskaya VP.

Sci Transl Med. 2012 Oct 3;4(154):154ra134. doi: 10.1126/scitranslmed.3003840.

43.

Fenton reaction induced cancer in wild type rats recapitulates genomic alterations observed in human cancer.

Akatsuka S, Yamashita Y, Ohara H, Liu YT, Izumiya M, Abe K, Ochiai M, Jiang L, Nagai H, Okazaki Y, Murakami H, Sekido Y, Arai E, Kanai Y, Hino O, Takahashi T, Nakagama H, Toyokuni S.

PLoS One. 2012;7(8):e43403. doi: 10.1371/journal.pone.0043403. Epub 2012 Aug 29.

44.

Ikaros is a critical target during simultaneous exposure to X-rays and N-ethyl-N-nitrosourea in mouse T-cell lymphomagenesis.

Hirano S, Kakinuma S, Amasaki Y, Nishimura M, Imaoka T, Fujimoto S, Hino O, Shimada Y.

Int J Cancer. 2013 Jan 15;132(2):259-68. doi: 10.1002/ijc.27668. Epub 2012 Jun 26.

45.

DNA binding protein A expression and methylation status in hepatocellular carcinoma and the adjacent tissue.

Yasen M, Obulhasim G, Kajino K, Mogushi K, Mizushima H, Tanaka S, Tanaka H, Hino O, Arii S.

Int J Oncol. 2012 Mar;40(3):789-97. doi: 10.3892/ijo.2011.1282. Epub 2011 Dec 6.

PMID:
22159460
46.

Recent advances in the management of chronic hepatitis B.

Kim SR, Yang J, Kudo M, Hino O.

Hepat Mon. 2011 Aug;11(8):601-11.

47.

LRRN4 and UPK3B are markers of primary mesothelial cells.

Kanamori-Katayama M, Kaiho A, Ishizu Y, Okamura-Oho Y, Hino O, Abe M, Kishimoto T, Sekihara H, Nakamura Y, Suzuki H, Forrest AR, Hayashizaki Y.

PLoS One. 2011;6(10):e25391. doi: 10.1371/journal.pone.0025391. Epub 2011 Oct 3.

48.

Feasibility of large-scale screening using N-ERC/mesothelin levels in the blood for the early diagnosis of malignant mesothelioma.

Imashimizu K, Shiomi K, Maeda M, Aoki N, Igarashi K, Suzuki F, Koizumi M, Suzuki K, Hino O.

Exp Ther Med. 2011 May;2(3):409-411. Epub 2011 Mar 8.

49.

Impact of renal failure on the tumor markers of mesothelioma, N-ERC/mesothelin and osteopontin.

Shiomi K, Shiomi S, Ishinaga Y, Sakuraba M, Hagiwara Y, Miyashita K, Maeda M, Suzuki K, Takahashi K, Hino O.

Anticancer Res. 2011 Apr;31(4):1427-30.

PMID:
21508397
50.

Autophagy-deficient mice develop multiple liver tumors.

Takamura A, Komatsu M, Hara T, Sakamoto A, Kishi C, Waguri S, Eishi Y, Hino O, Tanaka K, Mizushima N.

Genes Dev. 2011 Apr 15;25(8):795-800. doi: 10.1101/gad.2016211.

Supplemental Content

Support Center