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Items: 21


Perturbed myoepithelial cell differentiation in BRCA mutation carriers and in ductal carcinoma in situ.

Ding L, Su Y, Fassl A, Hinohara K, Qiu X, Harper NW, Huh SJ, Bloushtain-Qimron N, Jovanović B, Ekram M, Zi X, Hines WC, Alečković M, Gil Del Alcazar C, Caulfield RJ, Bonal DM, Nguyen QD, Merino VF, Choudhury S, Ethington G, Panos L, Grant M, Herlihy W, Au A, Rosson GD, Argani P, Richardson AL, Dillon D, Allred DC, Babski K, Kim EMH, McDonnell CH 3rd, Wagner J, Rowberry R, Bobolis K, Kleer CG, Hwang ES, Blum JL, Cristea S, Sicinski P, Fan R, Long HW, Sukumar S, Park SY, Garber JE, Bissell M, Yao J, Polyak K.

Nat Commun. 2019 Sep 13;10(1):4182. doi: 10.1038/s41467-019-12125-5.


Fibronectin rescues estrogen receptor α from lysosomal degradation in breast cancer cells.

Sampayo RG, Toscani AM, Rubashkin MG, Thi K, Masullo LA, Violi IL, Lakins JN, Cáceres A, Hines WC, Coluccio Leskow F, Stefani FD, Chialvo DR, Bissell MJ, Weaver VM, Simian M.

J Cell Biol. 2018 Aug 6;217(8):2777-2798. doi: 10.1083/jcb.201703037. Epub 2018 Jul 6.


Nuclear repartitioning of galectin-1 by an extracellular glycan switch regulates mammary morphogenesis.

Bhat R, Belardi B, Mori H, Kuo P, Tam A, Hines WC, Le QT, Bertozzi CR, Bissell MJ.

Proc Natl Acad Sci U S A. 2016 Aug 16;113(33):E4820-7. doi: 10.1073/pnas.1609135113. Epub 2016 Aug 5.


184AA3: a xenograft model of ER+ breast adenocarcinoma.

Hines WC, Kuhn I, Thi K, Chu B, Stanford-Moore G, Sampayo R, Garbe JC, Stampfer M, Borowsky AD, Bissell MJ.

Breast Cancer Res Treat. 2016 Jan;155(1):37-52. doi: 10.1007/s10549-015-3649-z. Epub 2015 Dec 12.


Modelling breast cancer requires identification and correction of a critical cell lineage-dependent transduction bias.

Hines WC, Yaswen P, Bissell MJ.

Nat Commun. 2015 Apr 21;6:6927. doi: 10.1038/ncomms7927.


Sorting out the FACS: a devil in the details.

Hines WC, Su Y, Kuhn I, Polyak K, Bissell MJ.

Cell Rep. 2014 Mar 13;6(5):779-81. doi: 10.1016/j.celrep.2014.02.021. No abstract available.


Coordinate regulation between expression levels of telomere-binding proteins and telomere length in breast carcinomas.

Butler KS, Hines WC, Heaphy CM, Griffith JK.

Cancer Med. 2012 Oct;1(2):165-75. doi: 10.1002/cam4.14. Epub 2012 Jul 24.


ECM microenvironment regulates collective migration and local dissemination in normal and malignant mammary epithelium.

Nguyen-Ngoc KV, Cheung KJ, Brenot A, Shamir ER, Gray RS, Hines WC, Yaswen P, Werb Z, Ewald AJ.

Proc Natl Acad Sci U S A. 2012 Sep 25;109(39):E2595-604. Epub 2012 Aug 23.


Age-associated gene expression in normal breast tissue mirrors qualitative age-at-incidence patterns for breast cancer.

Pirone JR, D'Arcy M, Stewart DA, Hines WC, Johnson M, Gould MN, Yaswen P, Jerry DJ, Smith Schneider S, Troester MA.

Cancer Epidemiol Biomarkers Prev. 2012 Oct;21(10):1735-44. doi: 10.1158/1055-9965.EPI-12-0451. Epub 2012 Aug 2.


The specific role of pRb in p16 (INK4A) -mediated arrest of normal and malignant human breast cells.

Bazarov AV, Lee WJ, Bazarov I, Bosire M, Hines WC, Stankovich B, Chicas A, Lowe SW, Yaswen P.

Cell Cycle. 2012 Mar 1;11(5):1008-13. doi: 10.4161/cc.11.5.19492. Epub 2012 Mar 1.


Breast field cancerization: isolation and comparison of telomerase-expressing cells in tumor and tumor adjacent, histologically normal breast tissue.

Trujillo KA, Hines WC, Vargas KM, Jones AC, Joste NE, Bisoffi M, Griffith JK.

Mol Cancer Res. 2011 Sep;9(9):1209-21. doi: 10.1158/1541-7786.MCR-10-0424. Epub 2011 Jul 20.


Why don't we get more cancer? A proposed role of the microenvironment in restraining cancer progression.

Bissell MJ, Hines WC.

Nat Med. 2011 Mar;17(3):320-9. doi: 10.1038/nm.2328. Review.


p16(INK4a) -mediated suppression of telomerase in normal and malignant human breast cells.

Bazarov AV, Van Sluis M, Hines WC, Bassett E, Beliveau A, Campeau E, Mukhopadhyay R, Lee WJ, Melodyev S, Zaslavsky Y, Lee L, Rodier F, Chicas A, Lowe SW, Benhattar J, Ren B, Campisi J, Yaswen P.

Aging Cell. 2010 Oct;9(5):736-46. doi: 10.1111/j.1474-9726.2010.00599.x. Epub 2010 Jul 14.


BORIS (CTCFL) is not expressed in most human breast cell lines and high grade breast carcinomas.

Hines WC, Bazarov AV, Mukhopadhyay R, Yaswen P.

PLoS One. 2010 Mar 17;5(3):e9738. doi: 10.1371/journal.pone.0009738.


Promotion of variant human mammary epithelial cell outgrowth by ionizing radiation: an agent-based model supported by in vitro studies.

Mukhopadhyay R, Costes SV, Bazarov AV, Hines WC, Barcellos-Hoff MH, Yaswen P.

Breast Cancer Res. 2010;12(1):R11. doi: 10.1186/bcr2477. Epub 2010 Feb 10.


Telomerase activation by c-Myc in human mammary epithelial cells requires additional genomic changes.

Bazarov AV, Hines WC, Mukhopadhyay R, Beliveau A, Melodyev S, Zaslavsky Y, Yaswen P.

Cell Cycle. 2009 Oct 15;8(20):3373-8. Epub 2009 Oct 19.


Assessment of the frequency of allelic imbalance in human tissue using a multiplex polymerase chain reaction system.

Heaphy CM, Hines WC, Butler KS, Haaland CM, Heywood G, Fischer EG, Bisoffi M, Griffith JK.

J Mol Diagn. 2007 Apr;9(2):266-71.


Protease nexin-1 expression is altered in human breast cancer.

Candia BJ, Hines WC, Heaphy CM, Griffith JK, Orlando RA.

Cancer Cell Int. 2006 May 31;6:16.


Telomere DNA content and allelic imbalance demonstrate field cancerization in histologically normal tissue adjacent to breast tumors.

Heaphy CM, Bisoffi M, Fordyce CA, Haaland CM, Hines WC, Joste NE, Griffith JK.

Int J Cancer. 2006 Jul 1;119(1):108-16.


Expression profiles of androgen independent bone metastatic prostate cancer cells indicate up-regulation of the putative serine-threonine kinase GS3955.

Bisoffi M, Klima I, Gresko E, Durfee PN, Hines WC, Griffith JK, Studer UE, Thalmann GN.

J Urol. 2004 Sep;172(3):1145-50.


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