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Items: 1 to 50 of 101

1.

Knockdown of CD44 expression decreases valve interstitial cell calcification in vitro.

Baugh L, Watson MC, Kemmerling EC, Hinds PW, Huggins GS, Black LD 3rd.

Am J Physiol Heart Circ Physiol. 2019 Jul 1;317(7):H26-H36. doi: 10.1152/ajpheart.00123.2018. Epub 2019 Apr 5.

PMID:
30951363
2.

CDK6 Antagonizes p53-Induced Responses during Tumorigenesis.

Bellutti F, Tigan AS, Nebenfuehr S, Dolezal M, Zojer M, Grausenburger R, Hartenberger S, Kollmann S, Doma E, Prchal-Murphy M, Uras IZ, Höllein A, Neuberg DS, Ebert BL, Ringler A, Mueller AC, Loizou JI, Hinds PW, Vogl C, Heller G, Kubicek S, Zuber J, Malumbres M, Farlik M, Villunger A, Kollmann K, Sexl V.

Cancer Discov. 2018 Jul;8(7):884-897. doi: 10.1158/2159-8290.CD-17-0912. Epub 2018 Jun 13.

3.

Proliferation of hippocampal progenitors relies on p27-dependent regulation of Cdk6 kinase activity.

Caron N, Genin EC, Marlier Q, Verteneuil S, Beukelaers P, Morel L, Hu MG, Hinds PW, Nguyen L, Vandenbosch R, Malgrange B.

Cell Mol Life Sci. 2018 Oct;75(20):3817-3827. doi: 10.1007/s00018-018-2832-x. Epub 2018 May 4.

PMID:
29728713
4.

Non-destructive two-photon excited fluorescence imaging identifies early nodules in calcific aortic-valve disease.

Baugh LM, Liu Z, Quinn KP, Osseiran S, Evans CL, Huggins GS, Hinds PW, Black LD 3rd, Georgakoudi I.

Nat Biomed Eng. 2017 Nov;1(11):914-924. doi: 10.1038/s41551-017-0152-3. Epub 2017 Nov 6.

5.

Conditional deletion of RB1 in the Tie2 lineage leads to aortic valve regurgitation.

Freytsis M, Baugh L, Liu Z, Georgakoudi I, Hinds PW, Black LD, Huggins GS.

PLoS One. 2018 Jan 5;13(1):e0190623. doi: 10.1371/journal.pone.0190623. eCollection 2018.

6.

Cell-Cycle Proteins Control Production of Neutrophil Extracellular Traps.

Amulic B, Knackstedt SL, Abu Abed U, Deigendesch N, Harbort CJ, Caffrey BE, Brinkmann V, Heppner FL, Hinds PW, Zychlinsky A.

Dev Cell. 2017 Nov 20;43(4):449-462.e5. doi: 10.1016/j.devcel.2017.10.013. Epub 2017 Nov 2.

7.

Cdk6 contributes to cytoskeletal stability in erythroid cells.

Uras IZ, Scheicher RM, Kollmann K, Glösmann M, Prchal-Murphy M, Tigan AS, Fux DA, Altamura S, Neves J, Muckenthaler MU, Bennett KL, Kubicek S, Hinds PW, von Lindern M, Sexl V.

Haematologica. 2017 Jun;102(6):995-1005. doi: 10.3324/haematol.2016.159947. Epub 2017 Mar 2.

8.

Commentary on Alfred G. Knudson, Jr.: "Hereditary Cancer, Oncogenes, and Antioncogenes".

Hinds PW.

Cancer Res. 2016 May 15;76(10):2851-3. doi: 10.1158/0008-5472.CAN-16-1142. No abstract available.

9.

Osteosarcoma: prognosis plateau warrants retinoblastoma pathway targeted therapy.

Ballatori SE, Hinds PW.

Signal Transduct Target Ther. 2016 Mar 25;1:16001. doi: 10.1038/sigtrans.2016.1. eCollection 2016. Review.

10.

CDK6-mediated repression of CD25 is required for induction and maintenance of Notch1-induced T-cell acute lymphoblastic leukemia.

Jena N, Sheng J, Hu JK, Li W, Zhou W, Lee G, Tsichlis N, Pathak A, Brown N, Deshpande A, Luo C, Hu GF, Hinds PW, Van Etten RA, Hu MG.

Leukemia. 2016 May;30(5):1033-43. doi: 10.1038/leu.2015.353. Epub 2015 Dec 28.

11.

Haploinsufficiency for BRCA1 leads to cell-type-specific genomic instability and premature senescence.

Sedic M, Skibinski A, Brown N, Gallardo M, Mulligan P, Martinez P, Keller PJ, Glover E, Richardson AL, Cowan J, Toland AE, Ravichandran K, Riethman H, Naber SP, Näär AM, Blasco MA, Hinds PW, Kuperwasser C.

Nat Commun. 2015 Jun 24;6:7505. doi: 10.1038/ncomms8505.

12.

Expression of oncogenic BRAFV600E in melanocytes induces Schwannian differentiation in vivo.

Luo C, Pietruska JR, Sheng J, Bronson RT, Hu MG, Cui R, Hinds PW.

Pigment Cell Melanoma Res. 2015 Sep;28(5):603-6. doi: 10.1111/pcmr.12384. Epub 2015 Jun 20. No abstract available.

13.

ClipR-59 interacts with Elmo2 and modulates myoblast fusion.

Sun Y, Ren W, Côté JF, Hinds PW, Hu X, Du K.

J Biol Chem. 2015 Mar 6;290(10):6130-40. doi: 10.1074/jbc.M114.616680. Epub 2015 Jan 8.

14.

A little pRB can lead to big problems.

Hinds PW.

Cancer Discov. 2014 Jul;4(7):764-5. doi: 10.1158/2159-8290.CD-14-0518.

15.

NDY1/KDM2B functions as a master regulator of polycomb complexes and controls self-renewal of breast cancer stem cells.

Kottakis F, Foltopoulou P, Sanidas I, Keller P, Wronski A, Dake BT, Ezell SA, Shen Z, Naber SP, Hinds PW, McNiel E, Kuperwasser C, Tsichlis PN.

Cancer Res. 2014 Jul 15;74(14):3935-46. doi: 10.1158/0008-5472.CAN-13-2733. Epub 2014 May 22.

16.

Transcription of angiogenin and ribonuclease 4 is regulated by RNA polymerase III elements and a CCCTC binding factor (CTCF)-dependent intragenic chromatin loop.

Sheng J, Luo C, Jiang Y, Hinds PW, Xu Z, Hu GF.

J Biol Chem. 2014 May 2;289(18):12520-34. doi: 10.1074/jbc.M114.551762. Epub 2014 Mar 21.

17.

Immune response to RB1-regulated senescence limits radiation-induced osteosarcoma formation.

Kansara M, Leong HS, Lin DM, Popkiss S, Pang P, Garsed DW, Walkley CR, Cullinane C, Ellul J, Haynes NM, Hicks R, Kuijjer ML, Cleton-Jansen AM, Hinds PW, Smyth MJ, Thomas DM.

J Clin Invest. 2013 Dec;123(12):5351-60. doi: 10.1172/JCI70559. Epub 2013 Nov 15.

18.

CDK6 binds and promotes the degradation of the EYA2 protein.

Kohrt D, Crary J, Zimmer M, Patrick AN, Ford HL, Hinds PW, Grossel MJ.

Cell Cycle. 2014;13(1):62-71. doi: 10.4161/cc.26755. Epub 2013 Oct 12.

19.

Loss of ARF sensitizes transgenic BRAFV600E mice to UV-induced melanoma via suppression of XPC.

Luo C, Sheng J, Hu MG, Haluska FG, Cui R, Xu Z, Tsichlis PN, Hu GF, Hinds PW.

Cancer Res. 2013 Jul 15;73(14):4337-48. doi: 10.1158/0008-5472.CAN-12-4454. Epub 2013 May 6.

20.

Cyclin D1 activity regulates autophagy and senescence in the mammary epithelium.

Brown NE, Jeselsohn R, Bihani T, Hu MG, Foltopoulou P, Kuperwasser C, Hinds PW.

Cancer Res. 2012 Dec 15;72(24):6477-89. doi: 10.1158/0008-5472.CAN-11-4139. Epub 2012 Oct 4.

21.

Matrix metalloprotease-1a promotes tumorigenesis and metastasis.

Foley CJ, Luo C, O'Callaghan K, Hinds PW, Covic L, Kuliopulos A.

J Biol Chem. 2012 Jul 13;287(29):24330-8. doi: 10.1074/jbc.M112.356303. Epub 2012 May 9.

22.
23.

Discrete phosphorylated retinoblastoma protein isoform expression in mouse tooth development.

Zhang W, Vazquez B, Andreeva V, Spear D, Kong E, Hinds PW, Yelick PC.

J Mol Histol. 2012 Jun;43(3):281-8. doi: 10.1007/s10735-012-9404-4. Epub 2012 Apr 4.

24.

Mitosis hit with an ATM transaction fee: aurora B-mediated activation of ATM during mitosis.

Bihani T, Hinds PW.

Mol Cell. 2011 Nov 18;44(4):513-4. doi: 10.1016/j.molcel.2011.11.001.

25.

Unbearable stress: collapse of the SSeCKS/AKAP12 scaffold leads to senescence and transformation.

Hinds PW.

Cell Cycle. 2011 Sep 1;10(17):2833-4. Epub 2011 Sep 1. No abstract available.

PMID:
21869601
26.

CDK6 kinase activity is required for thymocyte development.

Hu MG, Deshpande A, Schlichting N, Hinds EA, Mao C, Dose M, Hu GF, Van Etten RA, Gounari F, Hinds PW.

Blood. 2011 Jun 9;117(23):6120-31. doi: 10.1182/blood-2010-08-300517. Epub 2011 Apr 20.

27.

Overlapping and distinct pRb pathways in the mammalian auditory and vestibular organs.

Huang M, Sage C, Tang Y, Lee SG, Petrillo M, Hinds PW, Chen ZY.

Cell Cycle. 2011 Jan 15;10(2):337-51. Epub 2011 Jan 15.

28.

A role for the retinoblastoma protein as a regulator of mouse osteoblast cell adhesion: implications for osteogenesis and osteosarcoma formation.

Sosa-García B, Gunduz V, Vázquez-Rivera V, Cress WD, Wright G, Bian H, Hinds PW, Santiago-Cardona PG.

PLoS One. 2010 Nov 11;5(11):e13954. doi: 10.1371/journal.pone.0013954.

29.

p35 is required for CDK5 activation in cellular senescence.

Mao D, Hinds PW.

J Biol Chem. 2010 May 7;285(19):14671-80. doi: 10.1074/jbc.M109.066118. Epub 2010 Feb 24.

30.

Cyclin D1 kinase activity is required for the self-renewal of mammary stem and progenitor cells that are targets of MMTV-ErbB2 tumorigenesis.

Jeselsohn R, Brown NE, Arendt L, Klebba I, Hu MG, Kuperwasser C, Hinds PW.

Cancer Cell. 2010 Jan 19;17(1):65-76. doi: 10.1016/j.ccr.2009.11.024.

31.

Williams-Beuren syndrome-associated transcription factor TFII-I regulates osteogenic marker genes.

Lazebnik MB, Tussie-Luna MI, Hinds PW, Roy AL.

J Biol Chem. 2009 Dec 25;284(52):36234-9. doi: 10.1074/jbc.C109.063115. Epub 2009 Oct 30.

32.

Keeping quiet: a key role for dipeptidyl peptidase 2.

Hinds PW.

Cell Cycle. 2009 Sep 1;8(17):2683-4. Epub 2009 Sep 1. No abstract available.

PMID:
19717973
33.

Distinct subcellular distribution of cyclin dependent kinase 6.

Kohrt DM, Crary JI, Gocheva V, Hinds PW, Grossel MJ.

Cell Cycle. 2009 Sep 1;8(17):2837-43. Epub 2009 Sep 14.

34.

Melanocytic nevus-like hyperplasia and melanoma in transgenic BRAFV600E mice.

Goel VK, Ibrahim N, Jiang G, Singhal M, Fee S, Flotte T, Westmoreland S, Haluska FS, Hinds PW, Haluska FG.

Oncogene. 2009 Jun 11;28(23):2289-98. doi: 10.1038/onc.2009.95. Epub 2009 Apr 27.

35.

A requirement for cyclin-dependent kinase 6 in thymocyte development and tumorigenesis.

Hu MG, Deshpande A, Enos M, Mao D, Hinds EA, Hu GF, Chang R, Guo Z, Dose M, Mao C, Tsichlis PN, Gounari F, Hinds PW.

Cancer Res. 2009 Feb 1;69(3):810-8. doi: 10.1158/0008-5472.CAN-08-2473. Epub 2009 Jan 20.

36.

A role for NANOG in G1 to S transition in human embryonic stem cells through direct binding of CDK6 and CDC25A.

Zhang X, Neganova I, Przyborski S, Yang C, Cooke M, Atkinson SP, Anyfantis G, Fenyk S, Keith WN, Hoare SF, Hughes O, Strachan T, Stojkovic M, Hinds PW, Armstrong L, Lako M.

J Cell Biol. 2009 Jan 12;184(1):67-82. doi: 10.1083/jcb.200801009.

37.

Impaired bone development and increased mesenchymal progenitor cells in calvaria of RB1-/- mice.

Gutierrez GM, Kong E, Sabbagh Y, Brown NE, Lee JS, Demay MB, Thomas DM, Hinds PW.

Proc Natl Acad Sci U S A. 2008 Nov 25;105(47):18402-7. doi: 10.1073/pnas.0805925105. Epub 2008 Nov 19.

38.

A role for the cyclin box in the ubiquitin-mediated degradation of cyclin G1.

Piscopo DM, Hinds PW.

Cancer Res. 2008 Jul 15;68(14):5581-90. doi: 10.1158/0008-5472.CAN-07-6346.

39.

Too much of a good thing: the Prl-3 in p53's oyster.

Hinds PW.

Mol Cell. 2008 May 9;30(3):260-1. doi: 10.1016/j.molcel.2008.04.006.

40.
41.

The LxCxE pRb interaction domain of cyclin D1 is dispensable for murine development.

Landis MW, Brown NE, Baker GL, Shifrin A, Das M, Geng Y, Sicinski P, Hinds PW.

Cancer Res. 2007 Aug 15;67(16):7613-20.

42.

Timing is everything: regulation of Cdk1 and aneuploidy.

Tsichlis PN, Hatziapostolou M, Hinds PW.

Dev Cell. 2007 Apr;12(4):477-9.

44.

The retinoblastoma protein in osteoblast differentiation and osteosarcoma.

Deshpande A, Hinds PW.

Curr Mol Med. 2006 Nov;6(7):809-17. Review.

PMID:
17100605
45.

HES1 cooperates with pRb to activate RUNX2-dependent transcription.

Lee JS, Thomas DM, Gutierrez G, Carty SA, Yanagawa S, Hinds PW.

J Bone Miner Res. 2006 Jun;21(6):921-33.

46.
47.

Essential role of retinoblastoma protein in mammalian hair cell development and hearing.

Sage C, Huang M, Vollrath MA, Brown MC, Hinds PW, Corey DP, Vetter DE, Chen ZY.

Proc Natl Acad Sci U S A. 2006 May 9;103(19):7345-50. Epub 2006 Apr 28.

49.

Cyclin D1-dependent kinase activity in murine development and mammary tumorigenesis.

Landis MW, Pawlyk BS, Li T, Sicinski P, Hinds PW.

Cancer Cell. 2006 Jan;9(1):13-22.

50.

From cell cycle to differentiation: an expanding role for cdk6.

Grossel MJ, Hinds PW.

Cell Cycle. 2006 Feb;5(3):266-70. Epub 2006 Feb 6. Review.

PMID:
16410727

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