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Items: 22


Integrated lipidomic and transcriptomic analyses identify altered nerve triglycerides in mouse models of prediabetes and type 2 diabetes.

O'Brien PD, Guo K, Eid SA, Rumora AE, Hinder LM, Hayes JM, Mendelson FE, Hur J, Feldman EL.

Dis Model Mech. 2019 Dec 10. pii: dmm.042101. doi: 10.1242/dmm.042101. [Epub ahead of print]


Genome-wide DNA methylation profiling of human diabetic peripheral neuropathy in subjects with type 2 diabetes mellitus.

Guo K, Elzinga S, Eid S, Figueroa-Romero C, Hinder LM, Pacut C, Feldman EL, Hur J.

Epigenetics. 2019 Aug;14(8):766-779. doi: 10.1080/15592294.2019.1615352. Epub 2019 May 28.


Mitochondrial uncoupling has no effect on microvascular complications in type 2 diabetes.

Hinder LM, Sas KM, O'Brien PD, Backus C, Kayampilly P, Hayes JM, Lin CM, Zhang H, Shanmugam S, Rumora AE, Abcouwer SF, Brosius FC 3rd, Pennathur S, Feldman EL.

Sci Rep. 2019 Jan 29;9(1):881. doi: 10.1038/s41598-018-37376-y.


Juvenile murine models of prediabetes and type 2 diabetes develop neuropathy.

O'Brien PD, Hinder LM, Rumora AE, Hayes JM, Dauch JR, Backus C, Mendelson FE, Feldman EL.

Dis Model Mech. 2018 Dec 18;11(12). pii: dmm037374. doi: 10.1242/dmm.037374.


Abnormal RNA stability in amyotrophic lateral sclerosis.

Tank EM, Figueroa-Romero C, Hinder LM, Bedi K, Archbold HC, Li X, Weskamp K, Safren N, Paez-Colasante X, Pacut C, Thumma S, Paulsen MT, Guo K, Hur J, Ljungman M, Feldman EL, Barmada SJ.

Nat Commun. 2018 Jul 20;9(1):2845. doi: 10.1038/s41467-018-05049-z.


Transcriptional networks of progressive diabetic peripheral neuropathy in the db/db mouse model of type 2 diabetes: An inflammatory story.

Hinder LM, Murdock BJ, Park M, Bender DE, O'Brien PD, Rumora AE, Hur J, Feldman EL.

Exp Neurol. 2018 Jul;305:33-43. doi: 10.1016/j.expneurol.2018.03.011. Epub 2018 Mar 14.


Shared and distinct lipid-lipid interactions in plasma and affected tissues in a diabetic mouse model.

Sas KM, Lin J, Rajendiran TM, Soni T, Nair V, Hinder LM, Jagadish HV, Gardner TW, Abcouwer SF, Brosius FC 3rd, Feldman EL, Kretzler M, Michailidis G, Pennathur S.

J Lipid Res. 2018 Feb;59(2):173-183. doi: 10.1194/jlr.M077222. Epub 2017 Dec 13.


Obesity and the nervous system: more questions - Authors' reply.

Callaghan BC, O'Brien PD, Hinder LM, Feldman EL.

Lancet Neurol. 2017 Oct;16(10):774. doi: 10.1016/S1474-4422(17)30293-4. Epub 2017 Sep 12. No abstract available.


Dyslipidemia impairs mitochondrial trafficking and function in sensory neurons.

Rumora AE, Lentz SI, Hinder LM, Jackson SW, Valesano A, Levinson GE, Feldman EL.

FASEB J. 2018 Jan;32(1):195-207. doi: 10.1096/fj.201700206R. Epub 2017 Sep 13.


Neurological consequences of obesity.

O'Brien PD, Hinder LM, Callaghan BC, Feldman EL.

Lancet Neurol. 2017 Jun;16(6):465-477. doi: 10.1016/S1474-4422(17)30084-4. Review.


Dietary reversal of neuropathy in a murine model of prediabetes and metabolic syndrome.

Hinder LM, O'Brien PD, Hayes JM, Backus C, Solway AP, Sims-Robinson C, Feldman EL.

Dis Model Mech. 2017 Jun 1;10(6):717-725. doi: 10.1242/dmm.028530. Epub 2017 Apr 5.


Dual CCR2/CCR5 antagonist treatment attenuates adipose inflammation, but not microvascular complications in ob/ob mice.

O'Brien PD, Hinder LM, Parlee SD, Hayes JM, Backus C, Zhang H, Ma L, Sakowski SA, Brosius FC 3rd, Feldman EL.

Diabetes Obes Metab. 2017 Oct;19(10):1468-1472. doi: 10.1111/dom.12950. Epub 2017 Jun 2.


Comparative RNA-Seq transcriptome analyses reveal distinct metabolic pathways in diabetic nerve and kidney disease.

Hinder LM, Park M, Rumora AE, Hur J, Eichinger F, Pennathur S, Kretzler M, Brosius FC 3rd, Feldman EL.

J Cell Mol Med. 2017 Sep;21(9):2140-2152. doi: 10.1111/jcmm.13136. Epub 2017 Mar 8.


Tissue-specific metabolic reprogramming drives nutrient flux in diabetic complications.

Sas KM, Kayampilly P, Byun J, Nair V, Hinder LM, Hur J, Zhang H, Lin C, Qi NR, Michailidis G, Groop PH, Nelson RG, Darshi M, Sharma K, Schelling JR, Sedor JR, Pop-Busui R, Weinberg JM, Soleimanpour SA, Abcouwer SF, Gardner TW, Burant CF, Feldman EL, Kretzler M, Brosius FC 3rd, Pennathur S.

JCI Insight. 2016 Sep 22;1(15):e86976. doi: 10.1172/jci.insight.86976.


Transcriptional networks of murine diabetic peripheral neuropathy and nephropathy: common and distinct gene expression patterns.

Hur J, O'Brien PD, Nair V, Hinder LM, McGregor BA, Jagadish HV, Kretzler M, Brosius FC 3rd, Feldman EL.

Diabetologia. 2016 Jun;59(6):1297-306. doi: 10.1007/s00125-016-3913-8. Epub 2016 Mar 21.


The Metabolic Syndrome and Microvascular Complications in a Murine Model of Type 2 Diabetes.

Hur J, Dauch JR, Hinder LM, Hayes JM, Backus C, Pennathur S, Kretzler M, Brosius FC 3rd, Feldman EL.

Diabetes. 2015 Sep;64(9):3294-304. doi: 10.2337/db15-0133. Epub 2015 May 15.


ER stress in diabetic peripheral neuropathy: A new therapeutic target.

O'Brien PD, Hinder LM, Sakowski SA, Feldman EL.

Antioxid Redox Signal. 2014 Aug 1;21(4):621-33. doi: 10.1089/ars.2013.5807. Epub 2014 Feb 27. Review.


Long-chain acyl coenzyme A synthetase 1 overexpression in primary cultured Schwann cells prevents long chain fatty acid-induced oxidative stress and mitochondrial dysfunction.

Hinder LM, Figueroa-Romero C, Pacut C, Hong Y, Vivekanandan-Giri A, Pennathur S, Feldman EL.

Antioxid Redox Signal. 2014 Aug 1;21(4):588-600. doi: 10.1089/ars.2013.5248. Epub 2013 Oct 5.


Decreased glycolytic and tricarboxylic acid cycle intermediates coincide with peripheral nervous system oxidative stress in a murine model of type 2 diabetes.

Hinder LM, Vivekanandan-Giri A, McLean LL, Pennathur S, Feldman EL.

J Endocrinol. 2013 Jan 2;216(1):1-11. doi: 10.1530/JOE-12-0356. Print 2013 Jan.


Apolipoprotein E knockout as the basis for mouse models of dyslipidemia-induced neuropathy.

Hinder LM, Vincent AM, Hayes JM, McLean LL, Feldman EL.

Exp Neurol. 2013 Jan;239:102-10. doi: 10.1016/j.expneurol.2012.10.002. Epub 2012 Oct 8.


Bioenergetics in diabetic neuropathy: what we need to know.

Hinder LM, Vincent AM, Burant CF, Pennathur S, Feldman EL.

J Peripher Nerv Syst. 2012 May;17 Suppl 2:10-4. doi: 10.1111/j.1529-8027.2012.00389.x. Review.


Hyperlipidemia: a new therapeutic target for diabetic neuropathy.

Vincent AM, Hinder LM, Pop-Busui R, Feldman EL.

J Peripher Nerv Syst. 2009 Dec;14(4):257-67. doi: 10.1111/j.1529-8027.2009.00237.x. Review.

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