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Items: 11

1.

A robust pipeline with high replication rate for detection of somatic variants in the adaptive immune system as a source of common genetic variation in autoimmune disease.

Van Horebeek L, Hilven K, Mallants K, Van Nieuwenhuijze A, Kelkka T, Savola P, Mustjoki S, Schlenner SM, Liston A, Dubois B, Goris A.

Hum Mol Genet. 2019 Apr 15;28(8):1369-1380. doi: 10.1093/hmg/ddy425.

2.

Genetic Architecture of Adaptive Immune System Identifies Key Immune Regulators.

Lagou V, Garcia-Perez JE, Smets I, Van Horebeek L, Vandebergh M, Chen L, Mallants K, Prezzemolo T, Hilven K, Humblet-Baron S, Moisse M, Van Damme P, Boeckxstaens G, Bowness P, Dubois B, Dooley J, Liston A, Goris A.

Cell Rep. 2018 Oct 16;25(3):798-810.e6. doi: 10.1016/j.celrep.2018.09.048.

3.

Genetic basis for relapse rate in multiple sclerosis: Association with LRP2 genetic variation.

Hilven K, Vandebergh M, Smets I, Mallants K, Goris A, Dubois B.

Mult Scler. 2018 Nov;24(13):1773-1775. doi: 10.1177/1352458517749894. Epub 2018 Jan 5.

PMID:
29303040
4.

Immunologic profiles of multiple sclerosis treatments reveal shared early B cell alterations.

Dooley J, Pauwels I, Franckaert D, Smets I, Garcia-Perez JE, Hilven K, Danso-Abeam D, Terbeek J, Nguyen AT, De Muynck L, Decallonne B, Dubois B, Liston A, Goris A.

Neurol Neuroimmunol Neuroinflamm. 2016 May 10;3(4):e240. doi: 10.1212/NXI.0000000000000240. eCollection 2016 Aug.

5.

Analysis of Plasminogen Genetic Variants in Multiple Sclerosis Patients.

Sadovnick AD, Traboulsee AL, Bernales CQ, Ross JP, Forwell AL, Yee IM, Guillot-Noel L, Fontaine B, Cournu-Rebeix I, Alcina A, Fedetz M, Izquierdo G, Matesanz F, Hilven K, Dubois B, Goris A, Astobiza I, Alloza I, Antigüedad A, Vandenbroeck K, Akkad DA, Aktas O, Blaschke P, Buttmann M, Chan A, Epplen JT, Gerdes LA, Kroner A, Kubisch C, Kümpfel T, Lohse P, Rieckmann P, Zettl UK, Zipp F, Bertram L, Lill CM, Fernandez O, Urbaneja P, Leyva L, Alvarez-Cermeño JC, Arroyo R, Garagorri AM, García-Martínez A, Villar LM, Urcelay E, Malhotra S, Montalban X, Comabella M, Berger T, Fazekas F, Reindl M, Schmied MC, Zimprich A, Vilariño-Güell C.

G3 (Bethesda). 2016 Jul 7;6(7):2073-9. doi: 10.1534/g3.116.030841.

6.

Diagnostic value of cerebrospinal fluid Aβ ratios in preclinical Alzheimer's disease.

Adamczuk K, Schaeverbeke J, Vanderstichele HM, Lilja J, Nelissen N, Van Laere K, Dupont P, Hilven K, Poesen K, Vandenberghe R.

Alzheimers Res Ther. 2015 Dec 18;7(1):75. doi: 10.1186/s13195-015-0159-5.

7.

Amyloid imaging in cognitively normal older adults: comparison between (18)F-flutemetamol and (11)C-Pittsburgh compound B.

Adamczuk K, Schaeverbeke J, Nelissen N, Neyens V, Vandenbulcke M, Goffin K, Lilja J, Hilven K, Dupont P, Van Laere K, Vandenberghe R.

Eur J Nucl Med Mol Imaging. 2016 Jan;43(1):142-151. doi: 10.1007/s00259-015-3156-9. Epub 2015 Aug 12.

PMID:
26260650
8.

Genetic burden mirrors epidemiology of multiple sclerosis.

Hilven K, Goris A.

Mult Scler. 2015 Oct;21(11):1353-4. doi: 10.1177/1352458515596603. Epub 2015 Jul 21. No abstract available.

PMID:
26199351
9.

Burden of risk variants correlates with phenotype of multiple sclerosis.

Hilven K, Patsopoulos NA, Dubois B, Goris A.

Mult Scler. 2015 Nov;21(13):1670-80. doi: 10.1177/1352458514568174. Epub 2015 May 6.

PMID:
25948629
10.

Genetic variants are major determinants of CSF antibody levels in multiple sclerosis.

Goris A, Pauwels I, Gustavsen MW, van Son B, Hilven K, Bos SD, Celius EG, Berg-Hansen P, Aarseth J, Myhr KM, D'Alfonso S, Barizzone N, Leone MA, Martinelli Boneschi F, Sorosina M, Liberatore G, Kockum I, Olsson T, Hillert J, Alfredsson L, Bedri SK, Hemmer B, Buck D, Berthele A, Knier B, Biberacher V, van Pesch V, Sindic C, Bang Oturai A, Søndergaard HB, Sellebjerg F, Jensen PE, Comabella M, Montalban X, Pérez-Boza J, Malhotra S, Lechner-Scott J, Broadley S, Slee M, Taylor B, Kermode AG, Gourraud PA; International Multiple Sclerosis Genetics Consortium, Sawcer SJ, Andreassen BK, Dubois B, Harbo HF.

Brain. 2015 Mar;138(Pt 3):632-43. doi: 10.1093/brain/awu405. Epub 2015 Jan 22.

11.

No evidence for a role of rare CYP27B1 functional variations in multiple sclerosis.

Barizzone N, Pauwels I, Luciano B, Franckaert D, Guerini FR, Cosemans L, Hilven K, Salviati A, Dooley J, Danso-Abeam D, di Sapio A, Cavalla P, Decallonne B, Mathieu C, Liston A, Leone M, Dubois B, D'Alfonso S, Goris A.

Ann Neurol. 2013 Mar;73(3):433-7. doi: 10.1002/ana.23834. Epub 2013 Mar 11.

PMID:
23483640

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