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Nasal microbiota and symptom persistence in acute respiratory tract infections in infants.

Neumann RP, Hilty M, Xu B, Usemann J, Korten I, Mika M, Müller L, Latzin P, Frey U.

ERJ Open Res. 2018 Dec 3;4(4). pii: 00066-2018. doi: 10.1183/23120541.00066-2018. eCollection 2018 Oct.


Adrenal, thyroid and gonadal axes are affected at high altitude.

von Wolff M, Nakas CT, Tobler M, Merz TM, Hilty MP, Veldhuis JD, Huber AR, Pichler Hefti J.

Endocr Connect. 2018 Oct 1;7(10):1081-1089. doi: 10.1530/EC-18-0242.


Gut microbiota dynamics in travelers returning from India colonized with extended-spectrum cephalosporin-resistant Enterobacteriaceae: A longitudinal study.

Pires J, Kraemer JG, Kuenzli E, Kasraian S, Tinguely R, Hatz C, Endimiani A, Hilty M.

Travel Med Infect Dis. 2018 Oct 17. pii: S1477-8939(18)30367-3. doi: 10.1016/j.tmaid.2018.10.012. [Epub ahead of print]


Recruitment of sublingual microcirculation using handheld incident dark field imaging as a routine measurement tool during the postoperative de-escalation phase-a pilot study in post ICU cardiac surgery patients.

Uz Z, Ince C, Guerci P, Ince Y, P Araujo R, Ergin B, Hilty MP, van Gulik TM, de Mol BA.

Perioper Med (Lond). 2018 Aug 9;7:18. doi: 10.1186/s13741-018-0091-x. eCollection 2018.


Preserving fertility in an unconscious patient with Goodpasture syndrome-medicolegal and ethical aspects.

Stark D, Stiller R, Xie M, Weber D, Maggiorini M, Hilty MP.

J Intensive Care. 2018 Jul 23;6:40. doi: 10.1186/s40560-018-0311-y. eCollection 2018.


Microbial and host immune factors as drivers of COPD.

Mika M, Nita I, Morf L, Qi W, Beyeler S, Bernasconi E, Marsland BJ, Ott SR, von Garnier C, Hilty M.

ERJ Open Res. 2018 Jul 3;4(3). pii: 00015-2018. doi: 10.1183/23120541.00015-2018. eCollection 2018 Jul.


Response to: Comment on "Soluble Urokinase-Type Plasminogen Activator Receptor Plasma Concentration May Predict Susceptibility to High Altitude Pulmonary Edema".

Hilty MP, Zügel S, Schoeb M, Auinger K, Dehnert C, Maggiorini M.

Mediators Inflamm. 2018 May 2;2018:8036759. doi: 10.1155/2018/8036759. eCollection 2018. No abstract available.


Nasal Microbiota and Respiratory Tract Infections: The Role of Viral Detection.

Korten I, Ramsey K, Mika M, Usemann J, Frey U, Hilty M, Latzin P.

Am J Respir Crit Care Med. 2018 Mar 8. doi: 10.1164/rccm.201710-2020LE. [Epub ahead of print] No abstract available.


Patient selection for extracorporeal CO2 removal: a task as challenging as for ECMO therapy.

Hilty MP, Riva T, Cottini SR, Kleinert EM, Maggiorini A, Maggiorini M.

Minerva Anestesiol. 2018 Mar;84(3):410-411. doi: 10.23736/S0375-9393.18.12705-2. Epub 2018 Feb 5. No abstract available.


Influence of pig farming on the human's nasal microbiota: The key role of the airborne microbial communities.

Kraemer JG, Ramette A, Aebi S, Oppliger A, Hilty M.

Appl Environ Microbiol. 2018 Jan 12. pii: AEM.02470-17. doi: 10.1128/AEM.02470-17. [Epub ahead of print]


Carotid chemoreceptor control of muscle sympathetic nerve activity in hypobaric hypoxia.

Fisher JP, Flück D, Hilty MP, Lundby C.

Exp Physiol. 2018 Jan 1;103(1):77-89. doi: 10.1113/EP086493. Epub 2017 Nov 12.


Pneumococcal 23B Molecular Subtype Identified Using Whole Genome Sequencing.

Kapatai G, Sheppard CL, Troxler LJ, Litt DJ, Furrer J, Hilty M, Fry NK.

Genome Biol Evol. 2017 Aug 1;9(8):2122-2135. doi: 10.1093/gbe/evx092.


Validation of transpulmonary thermodilution variables in hemodynamically stable patients with heart diseases.

Hilty MP, Franzen DP, Wyss C, Biaggi P, Maggiorini M.

Ann Intensive Care. 2017 Aug 22;7(1):86. doi: 10.1186/s13613-017-0307-0.


Respiratory viruses in healthy infants and infants with cystic fibrosis: a prospective cohort study.

Korten I, Kieninger E, Klenja S, Mack I, Schläpfer N, Barbani MT, Regamey N, Kuehni CE, Hilty M, Frey U, Gorgievski M, Casaulta C, Latzin P; SCILD and BILD study groups.

Thorax. 2018 Jan;73(1):13-20. doi: 10.1136/thoraxjnl-2016-209553. Epub 2017 Aug 4.


Influence of the pneumococcal conjugate vaccines on the temporal variation of pneumococcal carriage and the nasal microbiota in healthy infants: a longitudinal analysis of a case-control study.

Mika M, Maurer J, Korten I, Allemann A, Aebi S, Brugger SD, Qi W, Frey U, Latzin P, Hilty M.

Microbiome. 2017 Jul 24;5(1):85. doi: 10.1186/s40168-017-0302-6.


Prevalence of extended-spectrum β-lactamase-producing Enterobacteriaceae and Methicillin-Resistant Staphylococcus aureus in pig farms in Switzerland.

Kraemer JG, Pires J, Kueffer M, Semaani E, Endimiani A, Hilty M, Oppliger A.

Sci Total Environ. 2017 Dec 15;603-604:401-405. doi: 10.1016/j.scitotenv.2017.06.110. Epub 2017 Jun 23.


Assessment of endothelial cell function and physiological microcirculatory reserve by video microscopy using a topical acetylcholine and nitroglycerin challenge.

Hilty MP, Pichler J, Ergin B, Hefti U, Merz TM, Ince C, Maggiorini M.

Intensive Care Med Exp. 2017 Dec;5(1):26. doi: 10.1186/s40635-017-0139-0. Epub 2017 May 18.


Pneumococcal carriage and serotype variation before and after introduction of pneumococcal conjugate vaccines in patients with acute otitis media in Switzerland.

Allemann A, Frey PM, Brugger SD, Hilty M.

Vaccine. 2017 Apr 4;35(15):1946-1953. doi: 10.1016/j.vaccine.2017.02.010. Epub 2017 Mar 6.


Detection of blood volumes and haemoglobin mass by means of CO re-breathing and indocyanine green and sodium fluorescein injections.

Keiser S, Meinild-Lundby AK, Steiner T, Trösch S, Rauber S, Krafft A, Burkhardt T, Hilty MP, Siebenmann C, Wehrlin JP, Lundby C.

Scand J Clin Lab Invest. 2017 May;77(3):164-174. doi: 10.1080/00365513.2016.1271908. Epub 2017 Mar 1.


Low flow veno-venous extracorporeal CO2 removal for acute hypercapnic respiratory failure.

Hilty MP, Riva T, Cottini SR, Kleinert EM, Maggiorini A, Maggiorini M.

Minerva Anestesiol. 2017 Aug;83(8):812-823. doi: 10.23736/S0375-9393.17.11524-5. Epub 2017 Mar 8.


First report of the macrolide efflux genetic assembly (MEGA) element in Haemophilus parainfluenzae.

Endimiani A, Allemann A, Wüthrich D, Lupo A, Hilty M.

Int J Antimicrob Agents. 2017 Feb;49(2):265-266. doi: 10.1016/j.ijantimicag.2016.11.006. Epub 2016 Dec 2. No abstract available.


Parasympathetic withdrawal increases heart rate after 2 weeks at 3454 m altitude.

Siebenmann C, Rasmussen P, Hug M, Keiser S, Flück D, Fisher JP, Hilty MP, Maggiorini M, Lundby C.

J Physiol. 2017 Mar 1;595(5):1619-1626. doi: 10.1113/JP273726. Epub 2017 Jan 24.


Interactions of Respiratory Viruses and the Nasal Microbiota during the First Year of Life in Healthy Infants.

Korten I, Mika M, Klenja S, Kieninger E, Mack I, Barbani MT, Gorgievski M, Frey U, Hilty M, Latzin P.

mSphere. 2016 Nov 23;1(6). pii: e00312-16. eCollection 2016 Nov-Dec.


Thermodilution-determined Internal Jugular Venous Flow.

Rasmussen P, Widmer M, Hilty MP, Hug M, Sørensen H, Ogoh S, Sato K, Secher NH, Maggiorini M, Lundby C.

Med Sci Sports Exerc. 2017 Apr;49(4):661-668. doi: 10.1249/MSS.0000000000001143.


Effect of alterations in blood volume with bed rest on glucose tolerance.

Dandanell S, Oberholzer L, Keiser S, Andersen AB, Haider T, Hilty MP, Meinild-Lundby AK, Lundby C.

J Appl Physiol (1985). 2016 Nov 1;121(5):1098-1105. doi: 10.1152/japplphysiol.00624.2016. Epub 2016 Sep 15.


Effect of Increased Blood Flow on Pulmonary Circulation Before and During High Altitude Acclimatization.

Hilty MP, Müller A, Flück D, Siebenmann C, Rasmussen P, Keiser S, Auinger K, Lundby C, Maggiorini M.

High Alt Med Biol. 2016 Dec;17(4):305-314. Epub 2016 Oct 18.


Intestinal colonisation with extended-spectrum cephalosporin-resistant Escherichia coli in Swiss pets: molecular features, risk factors and transmission with owners.

Pires J, Bernasconi OJ, Kasraian S, Hilty M, Perreten V, Endimiani A.

Int J Antimicrob Agents. 2016 Dec;48(6):759-760. doi: 10.1016/j.ijantimicag.2016.08.007. Epub 2016 Sep 20. No abstract available.


Polysaccharide Capsule Composition of Pneumococcal Serotype 19A Subtypes Is Unaltered among Subtypes and Independent of the Nutritional Environment.

Brugger SD, Troxler LJ, Rüfenacht S, Frey PM, Morand B, Geyer R, Mühlemann K, Höck S, Thormann W, Furrer J, Christen S, Hilty M.

Infect Immun. 2016 Oct 17;84(11):3152-3160. doi: 10.1128/IAI.00474-16. Print 2016 Nov.


Polyclonal Intestinal Colonization with Extended-Spectrum Cephalosporin-Resistant Enterobacteriaceae upon Traveling to India.

Pires J, Kuenzli E, Kasraian S, Tinguely R, Furrer H, Hilty M, Hatz C, Endimiani A.

Front Microbiol. 2016 Jul 12;7:1069. doi: 10.3389/fmicb.2016.01069. eCollection 2016.


Soluble Urokinase-Type Plasminogen Activator Receptor Plasma Concentration May Predict Susceptibility to High Altitude Pulmonary Edema.

Hilty MP, Zügel S, Schoeb M, Auinger K, Dehnert C, Maggiorini M.

Mediators Inflamm. 2016;2016:1942460. doi: 10.1155/2016/1942460. Epub 2016 Jun 9.


Serotype/serogroup-specific antibiotic non-susceptibility of invasive and non-invasive Streptococcus pneumoniae, Switzerland, 2004 to 2014.

Hauser C, Kronenberg A, Allemann A, Mühlemann K, Hilty M.

Euro Surveill. 2016 May 26;21(21). doi: 10.2807/1560-7917.ES.2016.21.21.30239.


The nasal microbiota in infants with cystic fibrosis in the first year of life: a prospective cohort study.

Mika M, Korten I, Qi W, Regamey N, Frey U, Casaulta C, Latzin P, Hilty M; SCILD study group.

Lancet Respir Med. 2016 Aug;4(8):627-635. doi: 10.1016/S2213-2600(16)30081-9. Epub 2016 May 11.


Ulcerating Ileocolitis in Severe Amatoxin Poisoning.

Hilty MP, Halama M, Zimmermann AK, Maggiorini M, Geier A.

Case Rep Gastrointest Med. 2015;2015:632085. doi: 10.1155/2015/632085. Epub 2015 Aug 18.


Twenty-eight days of exposure to 3454 m increases mitochondrial volume density in human skeletal muscle.

Jacobs RA, Lundby AK, Fenk S, Gehrig S, Siebenmann C, Flück D, Kirk N, Hilty MP, Lundby C.

J Physiol. 2016 Mar 1;594(5):1151-66. doi: 10.1113/JP271118. Epub 2015 Oct 28.


Antibiotic Susceptibility and Sequence Type Distribution of Ureaplasma Species Isolated from Genital Samples in Switzerland.

Schneider SC, Tinguely R, Droz S, Hilty M, Donà V, Bodmer T, Endimiani A.

Antimicrob Agents Chemother. 2015 Oct;59(10):6026-31. doi: 10.1128/AAC.00895-15. Epub 2015 Jul 20.


Heat training increases exercise capacity in hot but not in temperate conditions: a mechanistic counter-balanced cross-over study.

Keiser S, Flück D, Hüppin F, Stravs A, Hilty MP, Lundby C.

Am J Physiol Heart Circ Physiol. 2015 Sep;309(5):H750-61. doi: 10.1152/ajpheart.00138.2015. Epub 2015 Jul 6.


Hemoglobin mass and intravascular volume kinetics during and after exposure to 3,454-m altitude.

Siebenmann C, Cathomen A, Hug M, Keiser S, Lundby AK, Hilty MP, Goetze JP, Rasmussen P, Lundby C.

J Appl Physiol (1985). 2015 Nov 15;119(10):1194-201. doi: 10.1152/japplphysiol.01121.2014. Epub 2015 Mar 6.


Dynamics of the nasal microbiota in infancy: a prospective cohort study.

Mika M, Mack I, Korten I, Qi W, Aebi S, Frey U, Latzin P, Hilty M.

J Allergy Clin Immunol. 2015 Apr;135(4):905-12.e11. doi: 10.1016/j.jaci.2014.12.1909. Epub 2015 Jan 27.


Global phylogenomic analysis of nonencapsulated Streptococcus pneumoniae reveals a deep-branching classic lineage that is distinct from multiple sporadic lineages.

Hilty M, Wüthrich D, Salter SJ, Engel H, Campbell S, Sá-Leão R, de Lencastre H, Hermans P, Sadowy E, Turner P, Chewapreecha C, Diggle M, Pluschke G, McGee L, Köseoğlu Eser Ö, Low DE, Smith-Vaughan H, Endimiani A, Küffer M, Dupasquier M, Beaudoing E, Weber J, Bruggmann R, Hanage WP, Parkhill J, Hathaway LJ, Mühlemann K, Bentley SD.

Genome Biol Evol. 2014 Dec 4;6(12):3281-94. doi: 10.1093/gbe/evu263.


A point mutation in cpsE renders Streptococcus pneumoniae nonencapsulated and enhances its growth, adherence and competence.

Schaffner TO, Hinds J, Gould KA, Wüthrich D, Bruggmann R, Küffer M, Mühlemann K, Hilty M, Hathaway LJ.

BMC Microbiol. 2014 Aug 28;14:210. doi: 10.1186/s12866-014-0210-x.


Serotype epidemiology of invasive pneumococcal disease in Swiss adults: a nationwide population-based study.

Meichtry J, Born R, Küffer M, Zwahlen M, Albrich WC, Brugger SD, Mühlemann K, Hilty M.

Vaccine. 2014 Sep 8;32(40):5185-91. doi: 10.1016/j.vaccine.2014.07.060. Epub 2014 Jul 28.


Age, aerobic fitness, and cerebral perfusion during exercise: role of carbon dioxide.

Flück D, Braz ID, Keiser S, Hüppin F, Haider T, Hilty MP, Fisher JP, Lundby C.

Am J Physiol Heart Circ Physiol. 2014 Aug 15;307(4):H515-23.


A low-affinity penicillin-binding protein 2x variant is required for heteroresistance in Streptococcus pneumoniae.

Engel H, Mika M, Denapaite D, Hakenbeck R, Mühlemann K, Heller M, Hathaway LJ, Hilty M.

Antimicrob Agents Chemother. 2014 Jul;58(7):3934-41. doi: 10.1128/AAC.02547-14. Epub 2014 Apr 28.


The pneumococcal polysaccharide capsule and pneumolysin differentially affect CXCL8 and IL-6 release from cells of the upper and lower respiratory tract.

Küng E, Coward WR, Neill DR, Malak HA, Mühlemann K, Kadioglu A, Hilty M, Hathaway LJ.

PLoS One. 2014 Mar 24;9(3):e92355. doi: 10.1371/journal.pone.0092355. eCollection 2014.


Microbial communities in the respiratory tract of patients with interstitial lung disease.

Garzoni C, Brugger SD, Qi W, Wasmer S, Cusini A, Dumont P, Gorgievski-Hrisoho M, Mühlemann K, von Garnier C, Hilty M.

Thorax. 2013 Dec;68(12):1150-6. doi: 10.1136/thoraxjnl-2012-202917. Epub 2013 Aug 14.


Extended-spectrum cephalosporin-resistant Escherichia coli in community, specialized outpatient clinic and hospital settings in Switzerland.

Seiffert SN, Hilty M, Kronenberg A, Droz S, Perreten V, Endimiani A.

J Antimicrob Chemother. 2013 Oct;68(10):2249-54. doi: 10.1093/jac/dkt208. Epub 2013 Jun 12.


Heteroresistance to fosfomycin is predominant in Streptococcus pneumoniae and depends on the murA1 gene.

Engel H, Gutiérrez-Fernández J, Flückiger C, Martínez-Ripoll M, Mühlemann K, Hermoso JA, Hilty M, Hathaway LJ.

Antimicrob Agents Chemother. 2013 Jun;57(6):2801-8. doi: 10.1128/AAC.00223-13. Epub 2013 Apr 9.


Extended-spectrum cephalosporin-resistant Gram-negative organisms in livestock: an emerging problem for human health?

Seiffert SN, Hilty M, Perreten V, Endimiani A.

Drug Resist Updat. 2013 Feb-Apr;16(1-2):22-45. doi: 10.1016/j.drup.2012.12.001. Epub 2013 Feb 5. Review.


Characterisation and clinical features of Enterobacter cloacae bloodstream infections occurring at a tertiary care university hospital in Switzerland: is cefepime adequate therapy?

Hilty M, Sendi P, Seiffert SN, Droz S, Perreten V, Hujer AM, Bonomo RA, Mühlemann K, Endimiani A.

Int J Antimicrob Agents. 2013 Mar;41(3):236-49. doi: 10.1016/j.ijantimicag.2012.10.022. Epub 2013 Jan 10.

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