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Items: 1 to 50 of 149

1.

Learning Science Communication Skills Using Improvisation, Video Recordings, and Practice, Practice, Practice.

Ponzio NM, Alder J, Nucci M, Dannenfelser D, Hilton H, Linardopoulos N, Lutz C.

J Microbiol Biol Educ. 2018 Mar 30;19(1). pii: 19.1.15. doi: 10.1128/jmbe.v19i1.1433. eCollection 2018.

2.

Different Selected Mechanisms Attenuated the Inhibitory Interaction of KIR2DL1 with C2+ HLA-C in Two Indigenous Human Populations in Southern Africa.

Nemat-Gorgani N, Hilton HG, Henn BM, Lin M, Gignoux CR, Myrick JW, Werely CJ, Granka JM, Möller M, Hoal EG, Yawata M, Yawata N, Boelen L, Asquith B, Parham P, Norman PJ.

J Immunol. 2018 Apr 15;200(8):2640-2655. doi: 10.4049/jimmunol.1701780. Epub 2018 Mar 16.

PMID:
29549179
3.

Evaluation of a developmental hierarchy for breast cancer cells to assess risk-based patient selection for targeted treatment.

Bliss SA, Paul S, Pobiarzyn PW, Ayer S, Sinha G, Pant S, Hilton H, Sharma N, Cunha MF, Engelberth DJ, Greco SJ, Bryan M, Kucia MJ, Kakar SS, Ratajczak MZ, Rameshwar P.

Sci Rep. 2018 Jan 10;8(1):367. doi: 10.1038/s41598-017-18834-5.

4.

Estrogen and progesterone signalling in the normal breast and its implications for cancer development.

Hilton HN, Clarke CL, Graham JD.

Mol Cell Endocrinol. 2018 May 5;466:2-14. doi: 10.1016/j.mce.2017.08.011. Epub 2017 Aug 26. Review.

PMID:
28851667
5.

Class I HLA haplotypes form two schools that educate NK cells in different ways.

Horowitz A, Djaoud Z, Nemat-Gorgani N, Blokhuis J, Hilton HG, Béziat V, Malmberg KJ, Norman PJ, Guethlein LA, Parham P.

Sci Immunol. 2016 Sep 9;1(3):eaag1672. doi: 10.1126/sciimmunol.aag1672. Epub 2016 Sep 9.

PMID:
28783683
6.

Missing or altered self: human NK cell receptors that recognize HLA-C.

Hilton HG, Parham P.

Immunogenetics. 2017 Aug;69(8-9):567-579. doi: 10.1007/s00251-017-1001-y. Epub 2017 Jul 10. Review.

PMID:
28695291
7.

KIR2DS5 allotypes that recognize the C2 epitope of HLA-C are common among Africans and absent from Europeans.

Blokhuis JH, Hilton HG, Guethlein LA, Norman PJ, Nemat-Gorgani N, Nakimuli A, Chazara O, Moffett A, Parham P.

Immun Inflamm Dis. 2017 Dec;5(4):461-468. doi: 10.1002/iid3.178. Epub 2017 Jul 6.

8.

The Intergenic Recombinant HLA-B∗46:01 Has a Distinctive Peptidome that Includes KIR2DL3 Ligands.

Hilton HG, McMurtrey CP, Han AS, Djaoud Z, Guethlein LA, Blokhuis JH, Pugh JL, Goyos A, Horowitz A, Buchli R, Jackson KW, Bardet W, Bushnell DA, Robinson PJ, Mendoza JL, Birnbaum ME, Nielsen M, Garcia KC, Hildebrand WH, Parham P.

Cell Rep. 2017 May 16;19(7):1394-1405. doi: 10.1016/j.celrep.2017.04.059.

9.

Two Orangutan Species Have Evolved Different KIR Alleles and Haplotypes.

Guethlein LA, Norman PJ, Heijmans CM, de Groot NG, Hilton HG, Babrzadeh F, Abi-Rached L, Bontrop RE, Parham P.

J Immunol. 2017 Apr 15;198(8):3157-3169. doi: 10.4049/jimmunol.1602163. Epub 2017 Mar 6.

10.

Resurrecting KIR2DP1: A Key Intermediate in the Evolution of Human Inhibitory NK Cell Receptors That Recognize HLA-C.

Hilton HG, Blokhuis JH, Guethlein LA, Norman PJ, Parham P.

J Immunol. 2017 Mar 1;198(5):1961-1973. doi: 10.4049/jimmunol.1601835. Epub 2017 Jan 25.

11.

Class I HLA haplotypes form two schools that educate NK cells in different ways.

Horowitz A, Djaoud Z, Nemat-Gorgani N, Blokhuis J, Hilton HG, Béziat V, Malmberg KJ, Norman PJ, Guethlein LA, Parham P.

Sci Immunol. 2016 Sep;1(3). pii: eaag1672. Epub 2016 Sep 9.

12.

Deciphering the killer-cell immunoglobulin-like receptor system at super-resolution for natural killer and T-cell biology.

Béziat V, Hilton HG, Norman PJ, Traherne JA.

Immunology. 2017 Mar;150(3):248-264. doi: 10.1111/imm.12684. Epub 2016 Dec 14. Review.

13.

Persistence of circulating endothelial microparticles in COPD despite smoking cessation.

Strulovici-Barel Y, Staudt MR, Krause A, Gordon C, Tilley AE, Harvey BG, Kaner RJ, Hollmann C, Mezey JG, Bitter H, Pillai SG, Hilton H, Wolff G, Stevenson CS, Visvanathan S, Fine JS, Crystal RG.

Thorax. 2016 Dec;71(12):1137-1144. doi: 10.1136/thoraxjnl-2015-208274. Epub 2016 Jul 26.

14.

Haploinsufficiency of the Insulin Receptor in the Presence of a Splice-Site Mutation in Ppp2r2a Results in a Novel Digenic Mouse Model of Type 2 Diabetes.

Goldsworthy M, Bai Y, Li CM, Ge H, Lamas E, Hilton H, Esapa CT, Baker D, Baron W, Juan T, Véniant MM, Lloyd DJ, Cox RD.

Diabetes. 2016 May;65(5):1434-46. doi: 10.2337/db15-1276. Epub 2016 Feb 11.

15.

Deficiency of the zinc finger protein ZFP106 causes motor and sensory neurodegeneration.

Joyce PI, Fratta P, Landman AS, Mcgoldrick P, Wackerhage H, Groves M, Busam BS, Galino J, Corrochano S, Beskina OA, Esapa C, Ryder E, Carter S, Stewart M, Codner G, Hilton H, Teboul L, Tucker J, Lionikas A, Estabel J, Ramirez-Solis R, White JK, Brandner S, Plagnol V, Bennet DL, Abramov AY, Greensmith L, Fisher EM, Acevedo-Arozena A.

Hum Mol Genet. 2016 Jan 15;25(2):291-307. doi: 10.1093/hmg/ddv471. Epub 2015 Nov 24.

16.

Preface.

Clarke C, Dontu G, Hilton H, Meier-Abt F, Sartorius C.

J Mammary Gland Biol Neoplasia. 2015 Jun;20(1-2):5-7. doi: 10.1007/s10911-015-9345-0. No abstract available.

PMID:
26385464
17.

A Distinctive Cytoplasmic Tail Contributes to Low Surface Expression and Intracellular Retention of the Patr-AL MHC Class I Molecule.

Goyos A, Guethlein LA, Horowitz A, Hilton HG, Gleimer M, Brodsky FM, Parham P.

J Immunol. 2015 Oct 15;195(8):3725-36. doi: 10.4049/jimmunol.1500397. Epub 2015 Sep 14.

18.

Polymorphic HLA-C Receptors Balance the Functional Characteristics of KIR Haplotypes.

Hilton HG, Guethlein LA, Goyos A, Nemat-Gorgani N, Bushnell DA, Norman PJ, Parham P.

J Immunol. 2015 Oct 1;195(7):3160-70. doi: 10.4049/jimmunol.1501358. Epub 2015 Aug 26.

19.

Loss and Gain of Natural Killer Cell Receptor Function in an African Hunter-Gatherer Population.

Hilton HG, Norman PJ, Nemat-Gorgani N, Goyos A, Hollenbach JA, Henn BM, Gignoux CR, Guethlein LA, Parham P.

PLoS Genet. 2015 Aug 20;11(8):e1005439. doi: 10.1371/journal.pgen.1005439. eCollection 2015 Aug.

20.

Co-evolution of MHC class I and variable NK cell receptors in placental mammals.

Guethlein LA, Norman PJ, Hilton HG, Parham P.

Immunol Rev. 2015 Sep;267(1):259-82. doi: 10.1111/imr.12326. Review.

21.

Minireview: Progesterone Regulation of Proliferation in the Normal Human Breast and in Breast Cancer: A Tale of Two Scenarios?

Hilton HN, Graham JD, Clarke CL.

Mol Endocrinol. 2015 Sep;29(9):1230-42. doi: 10.1210/me.2015-1152. Epub 2015 Aug 12. Review.

22.

The Use of Recombinant Tissue Plasminogen Activator (rTPA) in The Treatment of Fibrinous Pleuropneumonia in Horses: 25 Cases (2007-2012).

Tomlinson JE, Byrne E, Pusterla N, Magdesian KG, Hilton HG, McGorum B, Davis E, Schoster A, Arroyo L, Dunkel B, Carslake H, Boston RC, Johnson AL.

J Vet Intern Med. 2015 Sep-Oct;29(5):1403-9. doi: 10.1111/jvim.13594. Epub 2015 Aug 7.

23.

Impact of progesterone on stem/progenitor cells in the human breast.

Hilton HN, Clarke CL.

J Mammary Gland Biol Neoplasia. 2015 Jun;20(1-2):27-37. doi: 10.1007/s10911-015-9339-y. Epub 2015 Aug 8.

PMID:
26254191
24.

The production of KIR-Fc fusion proteins and their use in a multiplex HLA class I binding assay.

Hilton HG, Moesta AK, Guethlein LA, Blokhuis J, Parham P, Norman PJ.

J Immunol Methods. 2015 Oct;425:79-87. doi: 10.1016/j.jim.2015.06.012. Epub 2015 Jun 19.

25.

Progesterone receptor A predominance is a discriminator of benefit from endocrine therapy in the ATAC trial.

Mote PA, Gompel A, Howe C, Hilton HN, Sestak I, Cuzick J, Dowsett M, Hugol D, Forgez P, Byth K, Graham JD, Clarke CL.

Breast Cancer Res Treat. 2015 Jun;151(2):309-18. doi: 10.1007/s10549-015-3397-0. Epub 2015 Apr 28.

PMID:
25917868
26.

Persistence of smoking-induced dysregulation of miRNA expression in the small airway epithelium despite smoking cessation.

Wang G, Wang R, Strulovici-Barel Y, Salit J, Staudt MR, Ahmed J, Tilley AE, Yee-Levin J, Hollmann C, Harvey BG, Kaner RJ, Mezey JG, Sridhar S, Pillai SG, Hilton H, Wolff G, Bitter H, Visvanathan S, Fine JS, Stevenson CS, Crystal RG.

PLoS One. 2015 Apr 17;10(4):e0120824. doi: 10.1371/journal.pone.0120824. eCollection 2015.

27.

ATMIN is a transcriptional regulator of both lung morphogenesis and ciliogenesis.

Goggolidou P, Stevens JL, Agueci F, Keynton J, Wheway G, Grimes DT, Patel SH, Hilton H, Morthorst SK, DiPaolo A, Williams DJ, Sanderson J, Khoronenkova SV, Powles-Glover N, Ermakov A, Esapa CT, Romero R, Dianov GL, Briscoe J, Johnson CA, Pedersen LB, Norris DP.

Development. 2014 Oct;141(20):3966-77. doi: 10.1242/dev.107755.

28.

Acquired convergence of hormone signaling in breast cancer: ER and PR transition from functionally distinct in normal breast to predictors of metastatic disease.

Hilton HN, Doan TB, Graham JD, Oakes SR, Silvestri A, Santucci N, Kantimm S, Huschtscha LI, Ormandy CJ, Funder JW, Simpson ER, Kuczek ES, Leedman PJ, Tilley WD, Fuller PJ, Muscat GE, Clarke CL.

Oncotarget. 2014 Sep 30;5(18):8651-64.

29.

A novel mouse Fgfr2 mutant, hobbyhorse (hob), exhibits complete XY gonadal sex reversal.

Siggers P, Carré GA, Bogani D, Warr N, Wells S, Hilton H, Esapa C, Hajihosseini MK, Greenfield A.

PLoS One. 2014 Jun 23;9(6):e100447. doi: 10.1371/journal.pone.0100447. eCollection 2014.

30.

Atmin mediates kidney morphogenesis by modulating Wnt signaling.

Goggolidou P, Hadjirin NF, Bak A, Papakrivopoulou E, Hilton H, Norris DP, Dean CH.

Hum Mol Genet. 2014 Oct 15;23(20):5303-16. doi: 10.1093/hmg/ddu246. Epub 2014 May 22.

31.

Dominant β-catenin mutations cause intellectual disability with recognizable syndromic features.

Tucci V, Kleefstra T, Hardy A, Heise I, Maggi S, Willemsen MH, Hilton H, Esapa C, Simon M, Buenavista MT, McGuffin LJ, Vizor L, Dodero L, Tsaftaris S, Romero R, Nillesen WN, Vissers LE, Kempers MJ, Vulto-van Silfhout AT, Iqbal Z, Orlando M, Maccione A, Lassi G, Farisello P, Contestabile A, Tinarelli F, Nieus T, Raimondi A, Greco B, Cantatore D, Gasparini L, Berdondini L, Bifone A, Gozzi A, Wells S, Nolan PM.

J Clin Invest. 2014 Apr;124(4):1468-82. doi: 10.1172/JCI70372. Epub 2014 Mar 10.

32.

Intraflagellar transport gene expression associated with short cilia in smoking and COPD.

Hessel J, Heldrich J, Fuller J, Staudt MR, Radisch S, Hollmann C, Harvey BG, Kaner RJ, Salit J, Yee-Levin J, Sridhar S, Pillai S, Hilton H, Wolff G, Bitter H, Visvanathan S, Fine J, Stevenson CS, Crystal RG, Tilley AE.

PLoS One. 2014 Jan 20;9(1):e85453. doi: 10.1371/journal.pone.0085453. eCollection 2014.

33.

Progesterone stimulates progenitor cells in normal human breast and breast cancer cells.

Hilton HN, Santucci N, Silvestri A, Kantimm S, Huschtscha LI, Graham JD, Clarke CL.

Breast Cancer Res Treat. 2014 Feb;143(3):423-33. doi: 10.1007/s10549-013-2817-2. Epub 2014 Jan 7.

PMID:
24395108
34.

The molecular landscape of the normal human breast--defining normal.

Hilton HN, Graham JD.

Breast Cancer Res. 2014 Jun 20;16(3):102. doi: 10.1186/bcr3680.

35.

Co-evolution of human leukocyte antigen (HLA) class I ligands with killer-cell immunoglobulin-like receptors (KIR) in a genetically diverse population of sub-Saharan Africans.

Norman PJ, Hollenbach JA, Nemat-Gorgani N, Guethlein LA, Hilton HG, Pando MJ, Koram KA, Riley EM, Abi-Rached L, Parham P.

PLoS Genet. 2013 Oct;9(10):e1003938. doi: 10.1371/journal.pgen.1003938. Epub 2013 Oct 31.

36.

RG7212 anti-TWEAK mAb inhibits tumor growth through inhibition of tumor cell proliferation and survival signaling and by enhancing the host antitumor immune response.

Yin X, Luistro L, Zhong H, Smith M, Nevins T, Schostack K, Hilton H, Lin TA, Truitt T, Biondi D, Wang X, Packman K, Rosinski J, Berkofsky-Fessler W, Tang JP, Pant S, Geho D, Vega-Harring S, Demario M, Levitsky H, Simcox M.

Clin Cancer Res. 2013 Oct 15;19(20):5686-98. doi: 10.1158/1078-0432.CCR-13-0405. Epub 2013 Aug 23.

37.

An intra-specific linkage map of lettuce (Lactuca sativa) and genetic analysis of postharvest discolouration traits.

Atkinson LD, McHale LK, Truco MJ, Hilton HW, Lynn J, Schut JW, Michelmore RW, Hand P, Pink DA.

Theor Appl Genet. 2013 Nov;126(11):2737-52.

PMID:
23959526
38.

Cigarette smoking induces small airway epithelial epigenetic changes with corresponding modulation of gene expression.

Buro-Auriemma LJ, Salit J, Hackett NR, Walters MS, Strulovici-Barel Y, Staudt MR, Fuller J, Mahmoud M, Stevenson CS, Hilton H, Ho MW, Crystal RG.

Hum Mol Genet. 2013 Dec 1;22(23):4726-38. doi: 10.1093/hmg/ddt326. Epub 2013 Jul 10.

39.

Suppression of glomerulonephritis in lupus-prone NZB × NZW mice by RN486, a selective inhibitor of Bruton's tyrosine kinase.

Mina-Osorio P, LaStant J, Keirstead N, Whittard T, Ayala J, Stefanova S, Garrido R, Dimaano N, Hilton H, Giron M, Lau KY, Hang J, Postelnek J, Kim Y, Min S, Patel A, Woods J, Ramanujam M, DeMartino J, Narula S, Xu D.

Arthritis Rheum. 2013 Sep;65(9):2380-91. doi: 10.1002/art.38047.

40.

Changed lineage composition is an early event in breast carcinogenesis.

Hilton HN, Kantimm S, Graham JD, Clarke CL.

Histol Histopathol. 2013 Sep;28(9):1197-204. doi: 10.14670/HH-28.1197. Epub 2013 Apr 15.

PMID:
23584793
42.

Scribble is required for normal epithelial cell-cell contacts and lumen morphogenesis in the mammalian lung.

Yates LL, Schnatwinkel C, Hazelwood L, Chessum L, Paudyal A, Hilton H, Romero MR, Wilde J, Bogani D, Sanderson J, Formstone C, Murdoch JN, Niswander LA, Greenfield A, Dean CH.

Dev Biol. 2013 Jan 15;373(2):267-80. doi: 10.1016/j.ydbio.2012.11.012. Epub 2012 Nov 27.

43.

Mutation at positively selected positions in the binding site for HLA-C shows that KIR2DL1 is a more refined but less adaptable NK cell receptor than KIR2DL3.

Hilton HG, Vago L, Older Aguilar AM, Moesta AK, Graef T, Abi-Rached L, Norman PJ, Guethlein LA, Fleischhauer K, Parham P.

J Immunol. 2012 Aug 1;189(3):1418-30. doi: 10.4049/jimmunol.1100431. Epub 2012 Jul 6.

44.

Syntactic comprehension in reading and listening: a study with French children with dyslexia.

Casalis S, Leuwers C, Hilton H.

J Learn Disabil. 2013 May-Jun;46(3):210-9. doi: 10.1177/0022219412449423. Epub 2012 Jun 18.

PMID:
22711663
45.

Systemic biomarkers of neutrophilic inflammation, tissue injury and repair in COPD patients with differing levels of disease severity.

Cockayne DA, Cheng DT, Waschki B, Sridhar S, Ravindran P, Hilton H, Kourteva G, Bitter H, Pillai SG, Visvanathan S, Müller KC, Holz O, Magnussen H, Watz H, Fine JS.

PLoS One. 2012;7(6):e38629. doi: 10.1371/journal.pone.0038629. Epub 2012 Jun 12.

46.

Progesterone and estrogen receptors segregate into different cell subpopulations in the normal human breast.

Hilton HN, Graham JD, Kantimm S, Santucci N, Cloosterman D, Huschtscha LI, Mote PA, Clarke CL.

Mol Cell Endocrinol. 2012 Sep 25;361(1-2):191-201. doi: 10.1016/j.mce.2012.04.010. Epub 2012 May 2.

PMID:
22580007
47.

RAS mutations in cutaneous squamous-cell carcinomas in patients treated with BRAF inhibitors.

Su F, Viros A, Milagre C, Trunzer K, Bollag G, Spleiss O, Reis-Filho JS, Kong X, Koya RC, Flaherty KT, Chapman PB, Kim MJ, Hayward R, Martin M, Yang H, Wang Q, Hilton H, Hang JS, Noe J, Lambros M, Geyer F, Dhomen N, Niculescu-Duvaz I, Zambon A, Niculescu-Duvaz D, Preece N, Robert L, Otte NJ, Mok S, Kee D, Ma Y, Zhang C, Habets G, Burton EA, Wong B, Nguyen H, Kockx M, Andries L, Lestini B, Nolop KB, Lee RJ, Joe AK, Troy JL, Gonzalez R, Hutson TE, Puzanov I, Chmielowski B, Springer CJ, McArthur GA, Sosman JA, Lo RS, Ribas A, Marais R.

N Engl J Med. 2012 Jan 19;366(3):207-15. doi: 10.1056/NEJMoa1105358.

48.

Generalized Fractional Derivative Anisotropic Viscoelastic Characterization.

Hilton HH.

Materials (Basel). 2012 Jan 18;5(1):169-191. doi: 10.3390/ma5010169.

49.

The multifaceted exosome: biogenesis, role in normal and aberrant cellular function, and frontiers for pharmacological and biomarker opportunities.

Pant S, Hilton H, Burczynski ME.

Biochem Pharmacol. 2012 Jun 1;83(11):1484-94. doi: 10.1016/j.bcp.2011.12.037. Epub 2011 Dec 31. Review.

PMID:
22230477
50.

Review: Immunogenetics of human placentation.

Parham P, Norman PJ, Abi-Rached L, Hilton HG, Guethlein LA.

Placenta. 2012 Feb;33 Suppl:S71-80. doi: 10.1016/j.placenta.2011.11.020. Epub 2011 Dec 15. Review.

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