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Items: 1 to 50 of 220

1.

Membrane-Associated RING-CH (MARCH) proteins down-regulate cell surface expression of the interleukin-6 receptor alpha chain (IL6Ra).

Babon JJ, Stockwell D, DiRago L, Zhang JG, Laktyushin A, Villadangos J, Ching A, Ishido S, Hilton DJ, Alexander WS, Nicola NA.

Biochem J. 2019 Sep 5. pii: BCJ20190577. doi: 10.1042/BCJ20190577. [Epub ahead of print]

PMID:
31488575
2.

Coherent two-dimensional Fourier transform spectroscopy using a 25 Tesla resistive magnet.

Paul J, Stevens CE, Smith RP, Dey P, Mapara V, Semenov D, McGill SA, Kaindl RA, Hilton DJ, Karaiskaj D.

Rev Sci Instrum. 2019 Jun;90(6):063901. doi: 10.1063/1.5055891.

PMID:
31255018
3.

Haemopedia RNA-seq: a database of gene expression during haematopoiesis in mice and humans.

Choi J, Baldwin TM, Wong M, Bolden JE, Fairfax KA, Lucas EC, Cole R, Biben C, Morgan C, Ramsay KA, Ng AP, Kauppi M, Corcoran LM, Shi W, Wilson N, Wilson MJ, Alexander WS, Hilton DJ, de Graaf CA.

Nucleic Acids Res. 2019 Jan 8;47(D1):D780-D785. doi: 10.1093/nar/gky1020.

4.

Biexcitons in monolayer transition metal dichalcogenides tuned by magnetic fields.

Stevens CE, Paul J, Cox T, Sahoo PK, Gutiérrez HR, Turkowski V, Semenov D, McGill SA, Kapetanakis MD, Perakis IE, Hilton DJ, Karaiskaj D.

Nat Commun. 2018 Sep 13;9(1):3720. doi: 10.1038/s41467-018-05643-1.

5.

scPipe: A flexible R/Bioconductor preprocessing pipeline for single-cell RNA-sequencing data.

Tian L, Su S, Dong X, Amann-Zalcenstein D, Biben C, Seidi A, Hilton DJ, Naik SH, Ritchie ME.

PLoS Comput Biol. 2018 Aug 10;14(8):e1006361. doi: 10.1371/journal.pcbi.1006361. eCollection 2018 Aug.

6.

Broadband ultrafast terahertz spectroscopy in the 25 T Split Florida-Helix.

Curtis JA, Burch AD, Barman B, Linn AG, McClintock LM, O'Beirne AL, Stiles MJ, Reno JL, McGill SA, Karaiskaj D, Hilton DJ.

Rev Sci Instrum. 2018 Jul;89(7):073901. doi: 10.1063/1.5023384.

PMID:
30068119
7.

PU.1 Is Required for the Developmental Progression of Multipotent Progenitors to Common Lymphoid Progenitors.

Pang SHM, de Graaf CA, Hilton DJ, Huntington ND, Carotta S, Wu L, Nutt SL.

Front Immunol. 2018 Jun 11;9:1264. doi: 10.3389/fimmu.2018.01264. eCollection 2018.

8.

Transcriptional profiling of eosinophil subsets in interleukin-5 transgenic mice.

Fairfax KA, Bolden JE, Robinson AJ, Lucas EC, Baldwin TM, Ramsay KA, Cole R, Hilton DJ, de Graaf CA.

J Leukoc Biol. 2018 Jul;104(1):195-204. doi: 10.1002/JLB.6MA1117-451R. Epub 2018 May 14.

9.

Identification of a Siglec-F+ granulocyte-macrophage progenitor.

Bolden JE, Lucas EC, Zhou G, O'Sullivan JA, de Graaf CA, McKenzie MD, Di Rago L, Baldwin TM, Shortt J, Alexander WS, Bochner BS, Ritchie ME, Hilton DJ, Fairfax KA.

J Leukoc Biol. 2018 Jul;104(1):123-133. doi: 10.1002/JLB.1MA1217-475R. Epub 2018 Apr 12.

10.

A preliminary molecular phylogeny of shield-bearer moths (Lepidoptera: Adeloidea: Heliozelidae) highlights rich undescribed diversity.

Milla L, van Nieukerken EJ, Vijverberg R, Doorenweerd C, Wilcox SA, Halsey M, Young DA, Jones TM, Kallies A, Hilton DJ.

Mol Phylogenet Evol. 2018 Mar;120:129-143. doi: 10.1016/j.ympev.2017.12.004. Epub 2017 Dec 8.

11.

MiSTIC, an integrated platform for the analysis of heterogeneity in large tumour transcriptome datasets.

Lemieux S, Sargeant T, Laperrière D, Ismail H, Boucher G, Rozendaal M, Lavallée VP, Ashton-Beaucage D, Wilhelm B, Hébert J, Hilton DJ, Mader S, Sauvageau G.

Nucleic Acids Res. 2017 Jul 27;45(13):e122. doi: 10.1093/nar/gkx338.

12.

Mutations in tropomyosin 4 underlie a rare form of human macrothrombocytopenia.

Pleines I, Woods J, Chappaz S, Kew V, Foad N, Ballester-Beltrán J, Aurbach K, Lincetto C, Lane RM, Schevzov G, Alexander WS, Hilton DJ, Astle WJ, Downes K, Nurden P, Westbury SK, Mumford AD, Obaji SG, Collins PW, Delerue F, Ittner LM, Bryce NS, Holliday M, Lucas CA, Hardeman EC, Ouwehand WH, Gunning PW, Turro E, Tijssen MR, Kile BT.

J Clin Invest. 2017 Mar 1;127(3):814-829. doi: 10.1172/JCI86154. Epub 2017 Jan 30.

13.

Haemopedia: An Expression Atlas of Murine Hematopoietic Cells.

de Graaf CA, Choi J, Baldwin TM, Bolden JE, Fairfax KA, Robinson AJ, Biben C, Morgan C, Ramsay K, Ng AP, Kauppi M, Kruse EA, Sargeant TJ, Seidenman N, D'Amico A, D'Ombrain MC, Lucas EC, Koernig S, Baz Morelli A, Wilson MJ, Dower SK, Williams B, Heazlewood SY, Hu Y, Nilsson SK, Wu L, Smyth GK, Alexander WS, Hilton DJ.

Stem Cell Reports. 2016 Sep 13;7(3):571-582. doi: 10.1016/j.stemcr.2016.07.007. Epub 2016 Aug 4.

14.

Setdb1-mediated H3K9 methylation is enriched on the inactive X and plays a role in its epigenetic silencing.

Keniry A, Gearing LJ, Jansz N, Liu J, Holik AZ, Hickey PF, Kinkel SA, Moore DL, Breslin K, Chen K, Liu R, Phillips C, Pakusch M, Biben C, Sheridan JM, Kile BT, Carmichael C, Ritchie ME, Hilton DJ, Blewitt ME.

Epigenetics Chromatin. 2016 May 18;9:16. doi: 10.1186/s13072-016-0064-6. eCollection 2016.

15.

Strong Quantum Coherence between Fermi Liquid Mahan Excitons.

Paul J, Stevens CE, Liu C, Dey P, McIntyre C, Turkowski V, Reno JL, Hilton DJ, Karaiskaj D.

Phys Rev Lett. 2016 Apr 15;116(15):157401. doi: 10.1103/PhysRevLett.116.157401. Epub 2016 Apr 14.

PMID:
27127985
16.

Optical Coherence in Atomic-Monolayer Transition-Metal Dichalcogenides Limited by Electron-Phonon Interactions.

Dey P, Paul J, Wang Z, Stevens CE, Liu C, Romero AH, Shan J, Hilton DJ, Karaiskaj D.

Phys Rev Lett. 2016 Mar 25;116(12):127402. doi: 10.1103/PhysRevLett.116.127402. Epub 2016 Mar 25.

PMID:
27058100
17.

Tribute to Donald Metcalf.

Murphy A, Murphy MJ, Begley CG, Stanley ER, Migliaccio AR, Kaushansky K, Ng AP, Alexander WS, Hilton DJ, Nicola NA.

Stem Cells. 2015 Dec;33(12):3397-421. doi: 10.1002/stem.2237.

18.

Heterogeneous nucleation and growth dynamics in the light-induced phase transition in vanadium dioxide.

Brady NF, Appavoo K, Seo M, Nag J, Prasankumar RP, Haglund RF Jr, Hilton DJ.

J Phys Condens Matter. 2016 Mar 31;28(12):125603. doi: 10.1088/0953-8984/28/12/125603. Epub 2016 Mar 2.

PMID:
26932975
19.

Causal Conceptions in Social Explanation and Moral Evaluation: A Historical Tour.

Alicke MD, Mandel DR, Hilton DJ, Gerstenberg T, Lagnado DA.

Perspect Psychol Sci. 2015 Nov;10(6):790-812. doi: 10.1177/1745691615601888.

PMID:
26581736
20.

In memoriam: Donald Metcalf (1929-2014)--A historical perspective of his contributions to hematology.

Nicola NA, Alexander WS, Hilton DJ, Ng AP.

Exp Hematol. 2015 Jun;43(6):425-7. No abstract available.

PMID:
26247071
21.

Genome-wide binding and mechanistic analyses of Smchd1-mediated epigenetic regulation.

Chen K, Hu J, Moore DL, Liu R, Kessans SA, Breslin K, Lucet IS, Keniry A, Leong HS, Parish CL, Hilton DJ, Lemmers RJ, van der Maarel SM, Czabotar PE, Dobson RC, Ritchie ME, Kay GF, Murphy JM, Blewitt ME.

Proc Natl Acad Sci U S A. 2015 Jul 7;112(27):E3535-44. doi: 10.1073/pnas.1504232112. Epub 2015 Jun 19.

22.

Biexciton formation and exciton coherent coupling in layered GaSe.

Dey P, Paul J, Moody G, Stevens CE, Glikin N, Kovalyuk ZD, Kudrynskyi ZR, Romero AH, Cantarero A, Hilton DJ, Karaiskaj D.

J Chem Phys. 2015 Jun 7;142(21):212422. doi: 10.1063/1.4917169.

PMID:
26049442
23.

Mouse prenatal platelet-forming lineages share a core transcriptional program but divergent dependence on MPL.

Potts KS, Sargeant TJ, Dawson CA, Josefsson EC, Hilton DJ, Alexander WS, Taoudi S.

Blood. 2015 Aug 6;126(6):807-16. doi: 10.1182/blood-2014-12-616607. Epub 2015 May 20.

PMID:
25995324
24.

Early lineage priming by trisomy of Erg leads to myeloproliferation in a Down syndrome model.

Ng AP, Hu Y, Metcalf D, Hyland CD, Ierino H, Phipson B, Wu D, Baldwin TM, Kauppi M, Kiu H, Di Rago L, Hilton DJ, Smyth GK, Alexander WS.

PLoS Genet. 2015 May 14;11(5):e1005211. doi: 10.1371/journal.pgen.1005211. eCollection 2015 May.

25.

Correction for Zhang et al., The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation.

Zhang JG, Farley A, Nicholson SE, Willson TA, Zugaro LM, Simpson RJ, Moritz RL, Cary D, Richardson R, Hausmann G, Kile BT, Kent SB, Alexander WS, Metcalf D, Hilton DJ, Nicola NA, Baca M.

Proc Natl Acad Sci U S A. 2015 Jun 2;112(22):E2979. doi: 10.1073/pnas.1507812112. Epub 2015 May 8. No abstract available.

26.

Donald Metcalf (1929-2014).

Hilton DJ, Nicola NA, Alexander WS, Roberts AW, Dunn AR.

Cell. 2015 Jan 29;160(3):361-2. No abstract available.

27.

"Heroes" and "villains" of world history across cultures.

Hanke K, Liu JH, Sibley CG, Paez D, Gaines SO Jr, Moloney G, Leong CH, Wagner W, Licata L, Klein O, Garber I, Böhm G, Hilton DJ, Valchev V, Khan SS, Cabecinhas R.

PLoS One. 2015 Feb 4;10(2):e0115641. doi: 10.1371/journal.pone.0115641. eCollection 2015.

28.

Ultrafast pump-probe spectroscopy in gallium arsenide at 25 T.

Curtis JA, Tokumoto T, Nolan NK, McClintock LM, Cherian JG, McGill SA, Hilton DJ.

Opt Lett. 2014 Oct 1;39(19):5772-5. doi: 10.1364/OL.39.005772.

PMID:
25360981
29.

Exploring two-dimensional electron gases with two-dimensional Fourier transform spectroscopy.

Paul J, Dey P, Tokumoto T, Reno JL, Hilton DJ, Karaiskaj D.

J Chem Phys. 2014 Oct 7;141(13):134505. doi: 10.1063/1.4896777.

PMID:
25296819
30.

A lineage of diploid platelet-forming cells precedes polyploid megakaryocyte formation in the mouse embryo.

Potts KS, Sargeant TJ, Markham JF, Shi W, Biben C, Josefsson EC, Whitehead LW, Rogers KL, Liakhovitskaia A, Smyth GK, Kile BT, Medvinsky A, Alexander WS, Hilton DJ, Taoudi S.

Blood. 2014 Oct 23;124(17):2725-9. doi: 10.1182/blood-2014-02-559468. Epub 2014 Jul 25.

PMID:
25079356
31.

Mpl expression on megakaryocytes and platelets is dispensable for thrombopoiesis but essential to prevent myeloproliferation.

Ng AP, Kauppi M, Metcalf D, Hyland CD, Josefsson EC, Lebois M, Zhang JG, Baldwin TM, Di Rago L, Hilton DJ, Alexander WS.

Proc Natl Acad Sci U S A. 2014 Apr 22;111(16):5884-9. doi: 10.1073/pnas.1404354111. Epub 2014 Apr 7.

32.

Ultrafast phase transition via catastrophic phonon collapse driven by plasmonic hot-electron injection.

Appavoo K, Wang B, Brady NF, Seo M, Nag J, Prasankumar RP, Hilton DJ, Pantelides ST, Haglund RF Jr.

Nano Lett. 2014 Mar 12;14(3):1127-33. doi: 10.1021/nl4044828. Epub 2014 Jan 31.

PMID:
24484272
33.

The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism.

Murphy JM, Czabotar PE, Hildebrand JM, Lucet IS, Zhang JG, Alvarez-Diaz S, Lewis R, Lalaoui N, Metcalf D, Webb AI, Young SN, Varghese LN, Tannahill GM, Hatchell EC, Majewski IJ, Okamoto T, Dobson RC, Hilton DJ, Babon JJ, Nicola NA, Strasser A, Silke J, Alexander WS.

Immunity. 2013 Sep 19;39(3):443-53. doi: 10.1016/j.immuni.2013.06.018. Epub 2013 Sep 5.

34.

Polycomb repressive complex 2 (PRC2) suppresses Eμ-myc lymphoma.

Lee SC, Phipson B, Hyland CD, Leong HS, Allan RS, Lun A, Hilton DJ, Nutt SL, Blewitt ME, Smyth GK, Alexander WS, Majewski IJ.

Blood. 2013 Oct 10;122(15):2654-63. doi: 10.1182/blood-2013-02-484055. Epub 2013 Aug 27.

PMID:
23982173
35.

Suppression of cytokine signaling: the SOCS perspective.

Linossi EM, Babon JJ, Hilton DJ, Nicholson SE.

Cytokine Growth Factor Rev. 2013 Jun;24(3):241-8. doi: 10.1016/j.cytogfr.2013.03.005. Epub 2013 Mar 30. Review.

36.

Cyclotron resonance spectroscopy in a high mobility two dimensional electron gas using characteristic matrix methods.

Hilton DJ.

Opt Express. 2012 Dec 31;20(28):29717-26. doi: 10.1364/OE.20.029717.

PMID:
23388799
37.

Production of a human neutralizing monoclonal antibody and its crystal structure in complex with ectodomain 3 of the interleukin-13 receptor α1.

Redpath NT, Xu Y, Wilson NJ, Fabri LJ, Baca M, Andrews AE, Braley H, Lu P, Ireland C, Ernst RE, Woods A, Forrest G, An Z, Zaller DM, Strohl WR, Luo CS, Czabotar PE, Garrett TP, Hilton DJ, Nash AD, Zhang JG, Nicola NA.

Biochem J. 2013 Apr 15;451(2):165-75. doi: 10.1042/BJ20121819.

PMID:
23384096
38.

Epigenetic regulator Smchd1 functions as a tumor suppressor.

Leong HS, Chen K, Hu Y, Lee S, Corbin J, Pakusch M, Murphy JM, Majewski IJ, Smyth GK, Alexander WS, Hilton DJ, Blewitt ME.

Cancer Res. 2013 Mar 1;73(5):1591-9. doi: 10.1158/0008-5472.CAN-12-3019. Epub 2012 Dec 26.

39.

NLRP1 inflammasome activation induces pyroptosis of hematopoietic progenitor cells.

Masters SL, Gerlic M, Metcalf D, Preston S, Pellegrini M, O'Donnell JA, McArthur K, Baldwin TM, Chevrier S, Nowell CJ, Cengia LH, Henley KJ, Collinge JE, Kastner DL, Feigenbaum L, Hilton DJ, Alexander WS, Kile BT, Croker BA.

Immunity. 2012 Dec 14;37(6):1009-23. doi: 10.1016/j.immuni.2012.08.027. Epub 2012 Dec 6.

40.

Thrombocytopenia and erythrocytosis in mice with a mutation in the gene encoding the hemoglobin β minor chain.

Kauppi M, Hilton AA, Metcalf D, Ng AP, Hyland CD, Collinge JE, Kile BT, Hilton DJ, Alexander WS.

Proc Natl Acad Sci U S A. 2012 Jan 10;109(2):576-81. doi: 10.1073/pnas.1119146109. Epub 2011 Dec 27.

41.

Reduced lymphocyte longevity and homeostatic proliferation in lamin B receptor-deficient mice results in profound and progressive lymphopenia.

Verhagen AM, de Graaf CA, Baldwin TM, Goradia A, Collinge JE, Kile BT, Metcalf D, Starr R, Hilton DJ.

J Immunol. 2012 Jan 1;188(1):122-34. doi: 10.4049/jimmunol.1100942. Epub 2011 Nov 21.

42.

Erg is required for self-renewal of hematopoietic stem cells during stress hematopoiesis in mice.

Ng AP, Loughran SJ, Metcalf D, Hyland CD, de Graaf CA, Hu Y, Smyth GK, Hilton DJ, Kile BT, Alexander WS.

Blood. 2011 Sep 1;118(9):2454-61. doi: 10.1182/blood-2011-03-344739. Epub 2011 Jun 14.

PMID:
21673349
43.

ChIP-seq analysis reveals distinct H3K27me3 profiles that correlate with transcriptional activity.

Young MD, Willson TA, Wakefield MJ, Trounson E, Hilton DJ, Blewitt ME, Oshlack A, Majewski IJ.

Nucleic Acids Res. 2011 Sep 1;39(17):7415-27. doi: 10.1093/nar/gkr416. Epub 2011 Jun 7.

44.

An ENU-induced mouse mutant of SHIP1 reveals a critical role of the stem cell isoform for suppression of macrophage activation.

Nguyen NY, Maxwell MJ, Ooms LM, Davies EM, Hilton AA, Collinge JE, Hilton DJ, Kile BT, Mitchell CA, Hibbs ML, Jane SM, Curtis DJ.

Blood. 2011 May 19;117(20):5362-71. doi: 10.1182/blood-2011-01-331041. Epub 2011 Mar 18.

PMID:
21421839
45.

ERG dependence distinguishes developmental control of hematopoietic stem cell maintenance from hematopoietic specification.

Taoudi S, Bee T, Hilton A, Knezevic K, Scott J, Willson TA, Collin C, Thomas T, Voss AK, Kile BT, Alexander WS, Pimanda JE, Hilton DJ.

Genes Dev. 2011 Feb 1;25(3):251-62. doi: 10.1101/gad.2009211. Epub 2011 Jan 18.

46.

Regulation of hematopoietic stem cells by their mature progeny.

de Graaf CA, Kauppi M, Baldwin T, Hyland CD, Metcalf D, Willson TA, Carpinelli MR, Smyth GK, Alexander WS, Hilton DJ.

Proc Natl Acad Sci U S A. 2010 Dec 14;107(50):21689-94. doi: 10.1073/pnas.1016166108. Epub 2010 Nov 29.

47.

Deficiency of 5-hydroxyisourate hydrolase causes hepatomegaly and hepatocellular carcinoma in mice.

Stevenson WS, Hyland CD, Zhang JG, Morgan PO, Willson TA, Gill A, Hilton AA, Viney EM, Bahlo M, Masters SL, Hennebry S, Richardson SJ, Nicola NA, Metcalf D, Hilton DJ, Roberts AW, Alexander WS.

Proc Natl Acad Sci U S A. 2010 Sep 21;107(38):16625-30. doi: 10.1073/pnas.1010390107. Epub 2010 Sep 7.

48.

Direct measurement of cyclotron coherence times of high-mobility two-dimensional electron gases.

Wang X, Hilton DJ, Reno JL, Mittleman DM, Kono J.

Opt Express. 2010 Jun 7;18(12):12354-61. doi: 10.1364/OE.18.012354.

PMID:
20588361
49.

Crystal structure of the entire ectodomain of gp130: insights into the molecular assembly of the tall cytokine receptor complexes.

Xu Y, Kershaw NJ, Luo CS, Soo P, Pocock MJ, Czabotar PE, Hilton DJ, Nicola NA, Garrett TP, Zhang JG.

J Biol Chem. 2010 Jul 9;285(28):21214-8. doi: 10.1074/jbc.C110.129502. Epub 2010 May 20.

50.

Opposing roles of polycomb repressive complexes in hematopoietic stem and progenitor cells.

Majewski IJ, Ritchie ME, Phipson B, Corbin J, Pakusch M, Ebert A, Busslinger M, Koseki H, Hu Y, Smyth GK, Alexander WS, Hilton DJ, Blewitt ME.

Blood. 2010 Aug 5;116(5):731-9. doi: 10.1182/blood-2009-12-260760. Epub 2010 May 5.

PMID:
20445021

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