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Items: 1 to 50 of 70

1.

Real-time volumetric microscopy of in vivo dynamics and large-scale samples with SCAPE 2.0.

Voleti V, Patel KB, Li W, Perez Campos C, Bharadwaj S, Yu H, Ford C, Casper MJ, Yan RW, Liang W, Wen C, Kimura KD, Targoff KL, Hillman EMC.

Nat Methods. 2019 Oct;16(10):1054-1062. doi: 10.1038/s41592-019-0579-4. Epub 2019 Sep 27.

PMID:
31562489
2.

Light-Sheet Microscopy in Neuroscience.

Hillman EMC, Voleti V, Li W, Yu H.

Annu Rev Neurosci. 2019 Jul 8;42:295-313. doi: 10.1146/annurev-neuro-070918-050357.

PMID:
31283896
3.

Characterization of Proprioceptive System Dynamics in Behaving Drosophila Larvae Using High-Speed Volumetric Microscopy.

Vaadia RD, Li W, Voleti V, Singhania A, Hillman EMC, Grueber WB.

Curr Biol. 2019 Mar 18;29(6):935-944.e4. doi: 10.1016/j.cub.2019.01.060. Epub 2019 Mar 7.

4.

Whole-Volume Clustering of Time Series Data from Zebrafish Brain Calcium Images via Mixture Modeling.

Nguyen HD, Ullmann JFP, McLachlan GJ, Voleti V, Li W, Hillman EMC, Reutens DC, Janke AL.

Stat Anal Data Min. 2018 Feb;11(1):5-16. doi: 10.1002/sam.11366. Epub 2017 Dec 6.

5.

High-speed 3D imaging of cellular activity in the brain using axially-extended beams and light sheets.

Hillman EM, Voleti V, Patel K, Li W, Yu H, Perez-Campos C, Benezra SE, Bruno RM, Galwaduge PT.

Curr Opin Neurobiol. 2018 Jun;50:190-200. doi: 10.1016/j.conb.2018.03.007. Epub 2018 Apr 9. Review.

6.

Skip the salt: your brain might thank you.

Shaik MA, Hillman EMC.

Nat Neurosci. 2018 Feb;21(2):154-155. doi: 10.1038/s41593-018-0068-6. No abstract available.

PMID:
29371655
7.

Perfusion-based fluorescence imaging method delineates diverse organs and identifies multifocal tumors using generic near-infrared molecular probes.

Miller J, Wang ST, Orukari I, Prior J, Sudlow G, Su X, Liang K, Tang R, Hillman EMC, Weilbaecher KN, Culver JP, Berezin MY, Achilefu S.

J Biophotonics. 2018 Apr;11(4):e201700232. doi: 10.1002/jbio.201700232. Epub 2018 Jan 3.

8.

In vivo Optical Imaging / Intravital Microscopy.

Marcu L, Hillman EMC.

J Biophotonics. 2017 Jun;10(6-7):760-761. doi: 10.1002/jbio.201770066. No abstract available.

PMID:
28661586
9.

Brain microvasculature defects and Glut1 deficiency syndrome averted by early repletion of the glucose transporter-1 protein.

Tang M, Gao G, Rueda CB, Yu H, Thibodeaux DN, Awano T, Engelstad KM, Sanchez-Quintero MJ, Yang H, Li F, Li H, Su Q, Shetler KE, Jones L, Seo R, McConathy J, Hillman EM, Noebels JL, De Vivo DC, Monani UR.

Nat Commun. 2017 Jan 20;8:14152. doi: 10.1038/ncomms14152.

10.

Correction to 'Wide-field optical mapping of neural activity and brain haemodynamics: considerations and novel approaches'.

Ma Y, Shaik MA, Kim SH, Kozberg MG, Thibodeaux DN, Zhao HT, Yu H, Hillman EM.

Philos Trans R Soc Lond B Biol Sci. 2017 Feb 19;372(1714). pii: 20160539. doi: 10.1098/rstb.2016.0539. Epub 2017 Jan 2. No abstract available.

11.

Resting-state hemodynamics are spatiotemporally coupled to synchronized and symmetric neural activity in excitatory neurons.

Ma Y, Shaik MA, Kozberg MG, Kim SH, Portes JP, Timerman D, Hillman EM.

Proc Natl Acad Sci U S A. 2016 Dec 27;113(52):E8463-E8471. doi: 10.1073/pnas.1525369113. Epub 2016 Dec 14.

12.

Neurovascular coupling develops alongside neural circuits in the postnatal brain.

Kozberg MG, Hillman EM.

Neurogenesis (Austin). 2016 Oct 28;3(1):e1244439. eCollection 2016.

13.

Introduction to the BIOMED 2016 feature issue.

Sampson DD, Dehghani H, Hillman EM, Wang TD.

Biomed Opt Express. 2016 Oct 5;7(11):4415. eCollection 2016 Nov 1.

14.

PLGA nano/microparticles loaded with cresyl violet as a tracer for drug delivery: Characterization and in-situ hyperspectral fluorescence and 2-photon localization.

Lunardi CN, Gomes AJ, Palepu S, Galwaduge PT, Hillman EM.

Mater Sci Eng C Mater Biol Appl. 2017 Jan 1;70(Pt 1):505-511. doi: 10.1016/j.msec.2016.09.020. Epub 2016 Sep 7.

PMID:
27770922
15.

Wide-field optical mapping of neural activity and brain haemodynamics: considerations and novel approaches.

Ma Y, Shaik MA, Kim SH, Kozberg MG, Thibodeaux DN, Zhao HT, Yu H, Hillman EM.

Philos Trans R Soc Lond B Biol Sci. 2016 Oct 5;371(1705). pii: 20150360. doi: 10.1098/rstb.2015.0360. Review. Erratum in: Philos Trans R Soc Lond B Biol Sci. 2017 Feb 19;372(1714):.

16.

Rapid Postnatal Expansion of Neural Networks Occurs in an Environment of Altered Neurovascular and Neurometabolic Coupling.

Kozberg MG, Ma Y, Shaik MA, Kim SH, Hillman EM.

J Neurosci. 2016 Jun 22;36(25):6704-17. doi: 10.1523/JNEUROSCI.2363-15.2016.

17.

Glioblastoma Induces Vascular Dysregulation in Nonenhancing Peritumoral Regions in Humans.

Chow DS, Horenstein CI, Canoll P, Lignelli A, Hillman EM, Filippi CG, Grinband J.

AJR Am J Roentgenol. 2016 May;206(5):1073-81. doi: 10.2214/AJR.15.14529. Epub 2016 Mar 23.

18.

Neurovascular and Immuno-Imaging: From Mechanisms to Therapies. Proceedings of the Inaugural Symposium.

Akassoglou K, Agalliu D, Chang CJ, Davalos D, Grutzendler J, Hillman EM, Khakh BS, Kleinfeld D, McGavern DB, Nelson SJ, Zlokovic BV.

Front Neurosci. 2016 Feb 22;10:46. doi: 10.3389/fnins.2016.00046. eCollection 2016.

19.

COX-2-Derived Prostaglandin E2 Produced by Pyramidal Neurons Contributes to Neurovascular Coupling in the Rodent Cerebral Cortex.

Lacroix A, Toussay X, Anenberg E, Lecrux C, Ferreirós N, Karagiannis A, Plaisier F, Chausson P, Jarlier F, Burgess SA, Hillman EM, Tegeder I, Murphy TH, Hamel E, Cauli B.

J Neurosci. 2015 Aug 26;35(34):11791-810. doi: 10.1523/JNEUROSCI.0651-15.2015.

20.

Simple wavefront correction framework for two-photon microscopy of in-vivo brain.

Galwaduge PT, Kim SH, Grosberg LE, Hillman EM.

Biomed Opt Express. 2015 Jul 23;6(8):2997-3013. doi: 10.1364/BOE.6.002997. eCollection 2015 Aug 1.

21.

Swept confocally-aligned planar excitation (SCAPE) microscopy for high speed volumetric imaging of behaving organisms.

Bouchard MB, Voleti V, Mendes CS, Lacefield C, Grueber WB, Mann RS, Bruno RM, Hillman EM.

Nat Photonics. 2015 Feb;9(2):113-119.

22.

Unsupervised deconvolution of dynamic imaging reveals intratumor vascular heterogeneity and repopulation dynamics.

Chen L, Choyke PL, Wang N, Clarke R, Bhujwalla ZM, Hillman EM, Wang G, Wang Y.

PLoS One. 2014 Nov 7;9(11):e112143. doi: 10.1371/journal.pone.0112143. eCollection 2014.

23.

Coupling mechanism and significance of the BOLD signal: a status report.

Hillman EM.

Annu Rev Neurosci. 2014;37:161-81. doi: 10.1146/annurev-neuro-071013-014111. Review.

24.

A critical role for the vascular endothelium in functional neurovascular coupling in the brain.

Chen BR, Kozberg MG, Bouchard MB, Shaik MA, Hillman EM.

J Am Heart Assoc. 2014 Jun 12;3(3):e000787. doi: 10.1161/JAHA.114.000787.

25.

Calcium imaging of infrared-stimulated activity in rodent brain.

Cayce JM, Bouchard MB, Chernov MM, Chen BR, Grosberg LE, Jansen ED, Hillman EM, Mahadevan-Jansen A.

Cell Calcium. 2014 Apr;55(4):183-90. doi: 10.1016/j.ceca.2014.01.004. Epub 2014 Jan 31.

26.

A noninvasive approach to determine viscoelastic properties of an individual adherent cell under fluid flow.

Qiu J, Baik AD, Lu XL, Hillman EM, Zhuang Z, Dong C, Guo XE.

J Biomech. 2014 Apr 11;47(6):1537-41. doi: 10.1016/j.jbiomech.2014.01.056. Epub 2014 Feb 14.

27.

Direct, intraoperative observation of ~0.1 Hz hemodynamic oscillations in awake human cortex: implications for fMRI.

Rayshubskiy A, Wojtasiewicz TJ, Mikell CB, Bouchard MB, Timerman D, Youngerman BE, McGovern RA, Otten ML, Canoll P, McKhann GM 2nd, Hillman EM.

Neuroimage. 2014 Feb 15;87:323-31. doi: 10.1016/j.neuroimage.2013.10.044. Epub 2013 Nov 1.

28.

Resolving the transition from negative to positive blood oxygen level-dependent responses in the developing brain.

Kozberg MG, Chen BR, DeLeo SE, Bouchard MB, Hillman EM.

Proc Natl Acad Sci U S A. 2013 Mar 12;110(11):4380-5. doi: 10.1073/pnas.1212785110. Epub 2013 Feb 20.

29.

Simultaneous tracking of 3D actin and microtubule strains in individual MLO-Y4 osteocytes under oscillatory flow.

Baik AD, Qiu J, Hillman EM, Dong C, Guo XE.

Biochem Biophys Res Commun. 2013 Feb 22;431(4):718-23. doi: 10.1016/j.bbrc.2013.01.052. Epub 2013 Jan 23.

30.

Dynamic contrast-enhanced optical imaging of in vivo organ function.

Amoozegar CB, Wang T, Bouchard MB, McCaslin AF, Blaner WS, Levenson RM, Hillman EM.

J Biomed Opt. 2012 Sep;17(9):96003-1. doi: 10.1117/1.JBO.17.9.096003.

31.

Simultaneous multiplane in vivo nonlinear microscopy using spectral encoding.

Grosberg LE, Chen BR, Hillman EM.

Opt Lett. 2012 Jul 15;37(14):2967-9. doi: 10.1364/OL.37.002967.

32.

Analysis of skin lesions using laminar optical tomography.

Muldoon TJ, Burgess SA, Chen BR, Ratner D, Hillman EM.

Biomed Opt Express. 2012 Jul 1;3(7):1701-12. doi: 10.1364/BOE.3.001701. Epub 2012 Jun 22.

33.

Theoretical Analysis of Novel Quasi-3D Microscopy of Cell Deformation.

Qiu J, Baik AD, Lu XL, Hillman EM, Zhuang Z, Guo XE.

Cell Mol Bioeng. 2011 Jun 1;5(2):165-172. Epub 2011 Dec 23.

34.

Advances in optics for biotechnology, medicine and surgery.

Hillman EM, Elson DS, Bigio IJ, Levenson RM, So PT.

Biomed Opt Express. 2012 Mar 1;3(3):531-2. doi: 10.1364/BOE.3.000531. Epub 2012 Feb 10.

35.

In vivo optical imaging and dynamic contrast methods for biomedical research.

Hillman EM, Amoozegar CB, Wang T, McCaslin AF, Bouchard MB, Mansfield J, Levenson RM.

Philos Trans A Math Phys Eng Sci. 2011 Nov 28;369(1955):4620-43. doi: 10.1098/rsta.2011.0264. Review.

36.

CAM-CM: a signal deconvolution tool for in vivo dynamic contrast-enhanced imaging of complex tissues.

Chen L, Chan TH, Choyke PL, Hillman EM, Chi CY, Bhujwalla ZM, Wang G, Wang SS, Szabo Z, Wang Y.

Bioinformatics. 2011 Sep 15;27(18):2607-9. doi: 10.1093/bioinformatics/btr436. Epub 2011 Jul 23.

37.

Spectral characterization and unmixing of intrinsic contrast in intact normal and diseased gastric tissues using hyperspectral two-photon microscopy.

Grosberg LE, Radosevich AJ, Asfaha S, Wang TC, Hillman EM.

PLoS One. 2011;6(5):e19925. doi: 10.1371/journal.pone.0019925. Epub 2011 May 16.

38.

Fiber-optic and articulating arm implementations of laminar optical tomography for clinical applications.

Burgess SA, Ratner D, Chen BR, Hillman EM.

Biomed Opt Express. 2010 Sep 2;1(3):780-790.

39.
40.

In vivo 3D morphology of astrocyte-vasculature interactions in the somatosensory cortex: implications for neurovascular coupling.

McCaslin AF, Chen BR, Radosevich AJ, Cauli B, Hillman EM.

J Cereb Blood Flow Metab. 2011 Mar;31(3):795-806. doi: 10.1038/jcbfm.2010.204. Epub 2010 Dec 8.

41.

Quasi-3D cytoskeletal dynamics of osteocytes under fluid flow.

Baik AD, Lu XL, Qiu J, Huo B, Hillman EM, Dong C, Guo XE.

Biophys J. 2010 Nov 3;99(9):2812-20. doi: 10.1016/j.bpj.2010.08.064.

42.

Optical imaging: a new window to the adult brain.

Taber KH, Hillman EM, Hurley RA.

J Neuropsychiatry Clin Neurosci. 2010 Fall;22(4):iv, 357-60. doi: 10.1176/appi.neuropsych.22.4.iv. No abstract available.

43.

High-speed vascular dynamics of the hemodynamic response.

Chen BR, Bouchard MB, McCaslin AF, Burgess SA, Hillman EM.

Neuroimage. 2011 Jan 15;54(2):1021-30. doi: 10.1016/j.neuroimage.2010.09.036. Epub 2010 Sep 19.

44.

Cortical depth-specific microvascular dilation underlies laminar differences in blood oxygenation level-dependent functional MRI signal.

Tian P, Teng IC, May LD, Kurz R, Lu K, Scadeng M, Hillman EM, De Crespigny AJ, D'Arceuil HE, Mandeville JB, Marota JJ, Rosen BR, Liu TT, Boas DA, Buxton RB, Dale AM, Devor A.

Proc Natl Acad Sci U S A. 2010 Aug 24;107(34):15246-51. doi: 10.1073/pnas.1006735107. Epub 2010 Aug 9.

45.
46.

Spatiotemporal precision and hemodynamic mechanism of optical point spreads in alert primates.

Sirotin YB, Hillman EM, Bordier C, Das A.

Proc Natl Acad Sci U S A. 2009 Oct 27;106(43):18390-5. doi: 10.1073/pnas.0905509106. Epub 2009 Oct 14.

47.

Ultra-fast multispectral optical imaging of cortical oxygenation, blood flow, and intracellular calcium dynamics.

Bouchard MB, Chen BR, Burgess SA, Hillman EM.

Opt Express. 2009 Aug 31;17(18):15670-8. doi: 10.1364/OE.17.015670.

48.

A system for high-resolution depth-resolved optical imaging of fluorescence and absorption contrast.

Yuan B, Burgess SA, Iranmahboob A, Bouchard MB, Lehrer N, Bordier C, Hillman EM.

Rev Sci Instrum. 2009 Apr;80(4):043706. doi: 10.1063/1.3117204.

49.

Topics in Biomedical Optics: introduction to the feature issue.

Culver JP, Drexler W, Drezek RA, Georgakoudi I, Hillman EM, Richards-Kortum R.

Appl Opt. 2009 Apr 1;48(10):TBO1-2.

PMID:
19340130
50.

Classification of NPY-expressing neocortical interneurons.

Karagiannis A, Gallopin T, Dávid C, Battaglia D, Geoffroy H, Rossier J, Hillman EM, Staiger JF, Cauli B.

J Neurosci. 2009 Mar 18;29(11):3642-59. doi: 10.1523/JNEUROSCI.0058-09.2009.

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