Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 222


Reinterpretation of the substrate specificity of the voltage-sensing phosphatase during dimerization.

Kruse M, Kohout SC, Hille B.

J Gen Physiol. 2019 Feb 4;151(2):258-263. doi: 10.1085/jgp.201812260. Epub 2019 Jan 8.


Understanding phosphoinositides: rare, dynamic, and essential membrane phospholipids.

Dickson EJ, Hille B.

Biochem J. 2019 Jan 7;476(1):1-23. doi: 10.1042/BCJ20180022. Review.


Optical approaches for visualization of arrestin binding to muscarinic receptor.

Jung SR, Hille B.

Methods Cell Biol. 2019;149:1-18. doi: 10.1016/bs.mcb.2017.11.001. Epub 2018 Jan 5.


Translocatable voltage-gated Ca2+ channel β subunits in α1-β complexes reveal competitive replacement yet no spontaneous dissociation.

Yeon JH, Park CG, Hille B, Suh BC.

Proc Natl Acad Sci U S A. 2018 Oct 16;115(42):E9934-E9943. doi: 10.1073/pnas.1809762115. Epub 2018 Sep 26.


Minimizing ATP depletion by oxygen scavengers for single-molecule fluorescence imaging in live cells.

Jung SR, Deng Y, Kushmerick C, Asbury CL, Hille B, Koh DS.

Proc Natl Acad Sci U S A. 2018 Jun 19;115(25):E5706-E5715. doi: 10.1073/pnas.1717724115. Epub 2018 Jun 4.


The founding of Journal of General Physiology: Membrane permeation and ion selectivity.

Hille B.

J Gen Physiol. 2018 Mar 5;150(3):389-400. doi: 10.1085/jgp.201711937. Epub 2018 Jan 23. Review.


Phosphatidylinositol 4,5-bisphosphate optical uncaging potentiates exocytosis.

Walter AM, Müller R, Tawfik B, Wierda KD, Pinheiro PS, Nadler A, McCarthy AW, Ziomkiewicz I, Kruse M, Reither G, Rettig J, Lehmann M, Haucke V, Hille B, Schultz C, Sørensen JB.

Elife. 2017 Oct 25;6. pii: e30203. doi: 10.7554/eLife.30203.


Proximal clustering between BK and CaV1.3 channels promotes functional coupling and BK channel activation at low voltage.

Vivas O, Moreno CM, Santana LF, Hille B.

Elife. 2017 Jun 30;6. pii: e28029. doi: 10.7554/eLife.28029.


Muscarinic receptor regulates extracellular signal regulated kinase by two modes of arrestin binding.

Jung SR, Kushmerick C, Seo JB, Koh DS, Hille B.

Proc Natl Acad Sci U S A. 2017 Jul 11;114(28):E5579-E5588. doi: 10.1073/pnas.1700331114. Epub 2017 Jun 26.


Fatty-acyl chain profiles of cellular phosphoinositides.

Traynor-Kaplan A, Kruse M, Dickson EJ, Dai G, Vivas O, Yu H, Whittington D, Hille B.

Biochim Biophys Acta Mol Cell Biol Lipids. 2017 May;1862(5):513-522. doi: 10.1016/j.bbalip.2017.02.002. Epub 2017 Feb 9.


Phosphoinositide 5- and 3-phosphatase activities of a voltage-sensing phosphatase in living cells show identical voltage dependence.

Keum D, Kruse M, Kim DI, Hille B, Suh BC.

Proc Natl Acad Sci U S A. 2016 Jun 28;113(26):E3686-95. doi: 10.1073/pnas.1606472113. Epub 2016 May 24. Erratum in: Proc Natl Acad Sci U S A. 2016 Aug 9;113(32):E4755.


Osmoregulatory inositol transporter SMIT1 modulates electrical activity by adjusting PI(4,5)P2 levels.

Dai G, Yu H, Kruse M, Traynor-Kaplan A, Hille B.

Proc Natl Acad Sci U S A. 2016 Jun 7;113(23):E3290-9. doi: 10.1073/pnas.1606348113. Epub 2016 May 23.


Extracellular ATP protects pancreatic duct epithelial cells from alcohol-induced damage through P2Y1 receptor-cAMP signal pathway.

Seo JB, Jung SR, Hille B, Koh DS.

Cell Biol Toxicol. 2016 Jun;32(3):229-47. doi: 10.1007/s10565-016-9331-3. Epub 2016 May 20.


Regulation of calcium and phosphoinositides at endoplasmic reticulum-membrane junctions.

Dickson EJ, Jensen JB, Hille B.

Biochem Soc Trans. 2016 Apr 15;44(2):467-73. doi: 10.1042/BST20150262. Review.


Dynamic formation of ER-PM junctions presents a lipid phosphatase to regulate phosphoinositides.

Dickson EJ, Jensen JB, Vivas O, Kruse M, Traynor-Kaplan AE, Hille B.

J Cell Biol. 2016 Apr 11;213(1):33-48. doi: 10.1083/jcb.201508106. Epub 2016 Apr 4.


GABAergic signaling in the rat pineal gland.

Yu H, Benitez SG, Jung SR, Farias Altamirano LE, Kruse M, Seo JB, Koh DS, Muñoz EM, Hille B.

J Pineal Res. 2016 Aug;61(1):69-81. doi: 10.1111/jpi.12328. Epub 2016 Apr 14.


Contributions of protein kinases and β-arrestin to termination of protease-activated receptor 2 signaling.

Jung SR, Seo JB, Deng Y, Asbury CL, Hille B, Koh DS.

J Gen Physiol. 2016 Mar;147(3):255-71. doi: 10.1085/jgp.201511477.


Dynamics of Phosphoinositide-Dependent Signaling in Sympathetic Neurons.

Kruse M, Vivas O, Traynor-Kaplan A, Hille B.

J Neurosci. 2016 Jan 27;36(4):1386-400. doi: 10.1523/JNEUROSCI.3535-15.2016.


High membrane permeability for melatonin.

Yu H, Dickson EJ, Jung SR, Koh DS, Hille B.

J Gen Physiol. 2016 Jan;147(1):63-76. doi: 10.1085/jgp.201511526.


Noradrenaline upregulates T-type calcium channels in rat pinealocytes.

Yu H, Seo JB, Jung SR, Koh DS, Hille B.

J Physiol. 2015 Feb 15;593(4):887-904. doi: 10.1113/jphysiol.2014.284208. Epub 2015 Jan 14.


Phosphoinositides regulate ion channels.

Hille B, Dickson EJ, Kruse M, Vivas O, Suh BC.

Biochim Biophys Acta. 2015 Jun;1851(6):844-56. doi: 10.1016/j.bbalip.2014.09.010. Epub 2014 Sep 18. Review.


Nerve growth factor sensitizes adult sympathetic neurons to the proinflammatory peptide bradykinin.

Vivas O, Kruse M, Hille B.

J Neurosci. 2014 Sep 3;34(36):11959-71. doi: 10.1523/JNEUROSCI.1536-14.2014.


Alterations of the Ca²⁺ signaling pathway in pancreatic beta-cells isolated from db/db mice.

Liang K, Du W, Lu J, Li F, Yang L, Xue Y, Hille B, Chen L.

Protein Cell. 2014 Oct;5(10):783-94. doi: 10.1007/s13238-014-0075-7. Epub 2014 Jul 24.


Golgi and plasma membrane pools of PI(4)P contribute to plasma membrane PI(4,5)P2 and maintenance of KCNQ2/3 ion channel current.

Dickson EJ, Jensen JB, Hille B.

Proc Natl Acad Sci U S A. 2014 Jun 3;111(22):E2281-90. doi: 10.1073/pnas.1407133111. Epub 2014 May 19.


Dynamic metabolic control of an ion channel.

Hille B, Dickson E, Kruse M, Falkenburger B.

Prog Mol Biol Transl Sci. 2014;123:219-47. doi: 10.1016/B978-0-12-397897-4.00008-5. Review.


Modulation of nicotinic receptor channels by adrenergic stimulation in rat pinealocytes.

Yoon JY, Jung SR, Hille B, Koh DS.

Am J Physiol Cell Physiol. 2014 Apr 15;306(8):C726-35. doi: 10.1152/ajpcell.00354.2013. Epub 2014 Feb 19.


Characterization of store-operated Ca2+ channels in pancreatic duct epithelia.

Kim MH, Seo JB, Burnett LA, Hille B, Koh DS.

Cell Calcium. 2013 Oct;54(4):266-75. doi: 10.1016/j.ceca.2013.07.002. Epub 2013 Aug 20.


The phosphoinositide sensitivity of the K(v) channel family.

Kruse M, Hille B.

Channels (Austin). 2013 Nov-Dec;7(6):530-6. doi: 10.4161/chan.25816. Epub 2013 Aug 1.


Quantitative properties and receptor reserve of the DAG and PKC branch of G(q)-coupled receptor signaling.

Falkenburger BH, Dickson EJ, Hille B.

J Gen Physiol. 2013 May;141(5):537-55. doi: 10.1085/jgp.201210887.


Quantitative properties and receptor reserve of the IP(3) and calcium branch of G(q)-coupled receptor signaling.

Dickson EJ, Falkenburger BH, Hille B.

J Gen Physiol. 2013 May;141(5):521-35. doi: 10.1085/jgp.201210886.


Orai-STIM-mediated Ca2+ release from secretory granules revealed by a targeted Ca2+ and pH probe.

Dickson EJ, Duman JG, Moody MW, Chen L, Hille B.

Proc Natl Acad Sci U S A. 2012 Dec 18;109(51):E3539-48. doi: 10.1073/pnas.1218247109. Epub 2012 Nov 26.


Regulation of voltage-gated potassium channels by PI(4,5)P2.

Kruse M, Hammond GR, Hille B.

J Gen Physiol. 2012 Aug;140(2):189-205. doi: 10.1085/jgp.201210806.


Optogenetic control of phosphoinositide metabolism.

Idevall-Hagren O, Dickson EJ, Hille B, Toomre DK, De Camilli P.

Proc Natl Acad Sci U S A. 2012 Aug 28;109(35):E2316-23. doi: 10.1073/pnas.1211305109. Epub 2012 Jul 30.


Actin cytoskeleton controls movement of intracellular organelles in pancreatic duct epithelial cells.

Jung SR, Seo JB, Shim D, Hille B, Koh DS.

Cell Calcium. 2012 Jun;51(6):459-69. doi: 10.1016/j.ceca.2012.04.004. Epub 2012 May 10.


Membrane-localized β-subunits alter the PIP2 regulation of high-voltage activated Ca2+ channels.

Suh BC, Kim DI, Falkenburger BH, Hille B.

Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):3161-6. doi: 10.1073/pnas.1121434109. Epub 2012 Feb 2.


Roger Dawson Milkman (1930-2011) geneticist.

Hille B, Berger E.

Genetics. 2011 Jul;188(3):489-90. doi: 10.1534/genetics.111.130518. No abstract available.


Testicular expression of Adora3i2 in Adora3 knockout mice reveals a role of mouse A3Ri2 and human A3Ri3 adenosine receptors in sperm.

Burnett LA, Blais EM, Unadkat JD, Hille B, Tilley SL, Babcock DF.

J Biol Chem. 2010 Oct 29;285(44):33662-70. doi: 10.1074/jbc.M110.156075. Epub 2010 Aug 23.


Modulation of high-voltage activated Ca(2+) channels by membrane phosphatidylinositol 4,5-bisphosphate.

Suh BC, Leal K, Hille B.

Neuron. 2010 Jul 29;67(2):224-38. doi: 10.1016/j.neuron.2010.07.001.


Phosphoinositides: lipid regulators of membrane proteins.

Falkenburger BH, Jensen JB, Dickson EJ, Suh BC, Hille B.

J Physiol. 2010 Sep 1;588(Pt 17):3179-85. doi: 10.1113/jphysiol.2010.192153. Epub 2010 Jun 2. Review.


Climate change and the integrity of science.

Gleick PH, Adams RM, Amasino RM, Anders E, Anderson DJ, Anderson WW, Anselin LE, Arroyo MK, Asfaw B, Ayala FJ, Bax A, Bebbington AJ, Bell G, Bennett MV, Bennetzen JL, Berenbaum MR, Berlin OB, Bjorkman PJ, Blackburn E, Blamont JE, Botchan MR, Boyer JS, Boyle EA, Branton D, Briggs SP, Briggs WR, Brill WJ, Britten RJ, Broecker WS, Brown JH, Brown PO, Brunger AT, Cairns J Jr, Canfield DE, Carpenter SR, Carrington JC, Cashmore AR, Castilla JC, Cazenave A, Chapin FS 3rd, Ciechanover AJ, Clapham DE, Clark WC, Clayton RN, Coe MD, Conwell EM, Cowling EB, Cowling RM, Cox CS, Croteau RB, Crothers DM, Crutzen PJ, Daily GC, Dalrymple GB, Dangl JL, Darst SA, Davies DR, Davis MB, De Camilli PV, Dean C, DeFries RS, Deisenhofer J, Delmer DP, DeLong EF, DeRosier DJ, Diener TO, Dirzo R, Dixon JE, Donoghue MJ, Doolittle RF, Dunne T, Ehrlich PR, Eisenstadt SN, Eisner T, Emanuel KA, Englander SW, Ernst WG, Falkowski PG, Feher G, Ferejohn JA, Fersht A, Fischer EH, Fischer R, Flannery KV, Frank J, Frey PA, Fridovich I, Frieden C, Futuyma DJ, Gardner WR, Garrett CJ, Gilbert W, Goldberg RB, Goodenough WH, Goodman CS, Goodman M, Greengard P, Hake S, Hammel G, Hanson S, Harrison SC, Hart SR, Hartl DL, Haselkorn R, Hawkes K, Hayes JM, Hille B, Hökfelt T, House JS, Hout M, Hunten DM, Izquierdo IA, Jagendorf AT, Janzen DH, Jeanloz R, Jencks CS, Jury WA, Kaback HR, Kailath T, Kay P, Kay SA, Kennedy D, Kerr A, Kessler RC, Khush GS, Kieffer SW, Kirch PV, Kirk K, Kivelson MG, Klinman JP, Klug A, Knopoff L, Kornberg H, Kutzbach JE, Lagarias JC, Lambeck K, Landy A, Langmuir CH, Larkins BA, Le Pichon XT, Lenski RE, Leopold EB, Levin SA, Levitt M, Likens GE, Lippincott-Schwartz J, Lorand L, Lovejoy CO, Lynch M, Mabogunje AL, Malone TF, Manabe S, Marcus J, Massey DS, McWilliams JC, Medina E, Melosh HJ, Meltzer DJ, Michener CD, Miles EL, Mooney HA, Moore PB, Morel FM, Mosley-Thompson ES, Moss B, Munk WH, Myers N, Nair GB, Nathans J, Nester EW, Nicoll RA, Novick RP, O'Connell JF, Olsen PE, Opdyke ND, Oster GF, Ostrom E, Pace NR, Paine RT, Palmiter RD, Pedlosky J, Petsko GA, Pettengill GH, Philander SG, Piperno DR, Pollard TD, Price PB Jr, Reichard PA, Reskin BF, Ricklefs RE, Rivest RL, Roberts JD, Romney AK, Rossmann MG, Russell DW, Rutter WJ, Sabloff JA, Sagdeev RZ, Sahlins MD, Salmond A, Sanes JR, Schekman R, Schellnhuber J, Schindler DW, Schmitt J, Schneider SH, Schramm VL, Sederoff RR, Shatz CJ, Sherman F, Sidman RL, Sieh K, Simons EL, Singer BH, Singer MF, Skyrms B, Sleep NH, Smith BD, Snyder SH, Sokal RR, Spencer CS, Steitz TA, Strier KB, Südhof TC, Taylor SS, Terborgh J, Thomas DH, Thompson LG, Tjian RT, Turner MG, Uyeda S, Valentine JW, Valentine JS, Van Etten JL, van Holde KE, Vaughan M, Verba S, von Hippel PH, Wake DB, Walker A, Walker JE, Watson EB, Watson PJ, Weigel D, Wessler SR, West-Eberhard MJ, White TD, Wilson WJ, Wolfenden RV, Wood JA, Woodwell GM, Wright HE Jr, Wu C, Wunsch C, Zoback ML.

Science. 2010 May 7;328(5979):689-90. doi: 10.1126/science.328.5979.689. No abstract available. Erratum in: Science. 2010 May 14;328(5980):826.


Cyclic AMP potentiates Ca2+-dependent exocytosis in pancreatic duct epithelial cells.

Jung SR, Hille B, Nguyen TD, Koh DS.

J Gen Physiol. 2010 May;135(5):527-43. doi: 10.1085/jgp.200910355.


Characteristics and functions of {alpha}-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptors expressed in mouse pancreatic {alpha}-cells.

Cho JH, Chen L, Kim MH, Chow RH, Hille B, Koh DS.

Endocrinology. 2010 Apr;151(4):1541-50. doi: 10.1210/en.2009-0362. Epub 2010 Feb 26.


Kinetics of PIP2 metabolism and KCNQ2/3 channel regulation studied with a voltage-sensitive phosphatase in living cells.

Falkenburger BH, Jensen JB, Hille B.

J Gen Physiol. 2010 Feb;135(2):99-114. doi: 10.1085/jgp.200910345.


Kinetics of M1 muscarinic receptor and G protein signaling to phospholipase C in living cells.

Falkenburger BH, Jensen JB, Hille B.

J Gen Physiol. 2010 Feb;135(2):81-97. doi: 10.1085/jgp.200910344.


Pharmacological targeting of native CatSper channels reveals a required role in maintenance of sperm hyperactivation.

Carlson AE, Burnett LA, del Camino D, Quill TA, Hille B, Chong JA, Moran MM, Babcock DF.

PLoS One. 2009 Aug 31;4(8):e6844. doi: 10.1371/journal.pone.0006844.


Fluorescence changes reveal kinetic steps of muscarinic receptor-mediated modulation of phosphoinositides and Kv7.2/7.3 K+ channels.

Jensen JB, Lyssand JS, Hague C, Hille B.

J Gen Physiol. 2009 Apr;133(4):347-59. doi: 10.1085/jgp.200810075.


Control of granule mobility and exocytosis by Ca2+ -dependent formation of F-actin in pancreatic duct epithelial cells.

Jung SR, Kim MH, Hille B, Koh DS.

Traffic. 2009 Apr;10(4):392-410. doi: 10.1111/j.1600-0854.2009.00884.x. Epub 2009 Jan 24.


Tissue-specific PKA inhibition using a chemical genetic approach and its application to studies on sperm capacitation.

Morgan DJ, Weisenhaus M, Shum S, Su T, Zheng R, Zhang C, Shokat KM, Hille B, Babcock DF, McKnight GS.

Proc Natl Acad Sci U S A. 2008 Dec 30;105(52):20740-5. doi: 10.1073/pnas.0810971105. Epub 2008 Dec 12.


Glutamate transporter-mediated glutamate secretion in the mammalian pineal gland.

Kim MH, Uehara S, Muroyama A, Hille B, Moriyama Y, Koh DS.

J Neurosci. 2008 Oct 22;28(43):10852-63. doi: 10.1523/JNEUROSCI.0894-08.2008.


Functional stoichiometry of the unitary calcium-release-activated calcium channel.

Ji W, Xu P, Li Z, Lu J, Liu L, Zhan Y, Chen Y, Hille B, Xu T, Chen L.

Proc Natl Acad Sci U S A. 2008 Sep 9;105(36):13668-73. doi: 10.1073/pnas.0806499105. Epub 2008 Aug 29.

Supplemental Content

Support Center