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Items: 28


The yin and yang of KV channels in cerebral small vessel pathologies.

Koide M, Moshkforoush A, Tsoukias NM, Hill-Eubanks DC, Wellman GC, Nelson MT, Dabertrand F.

Microcirculation. 2018 Jan;25(1). doi: 10.1111/micc.12436. Review.


Lack of direct effect of adiponectin on vascular smooth muscle cell BKCa channels or Ca2+ signaling in the regulation of small artery pressure-induced constriction.

Baylie R, Ahmed M, Bonev AD, Hill-Eubanks DC, Heppner TJ, Nelson MT, Greenstein AS.

Physiol Rep. 2017 Aug;5(16). pii: e13337. doi: 10.14814/phy2.13337.


Pressure-induced oxidative activation of PKG enables vasoregulation by Ca2+ sparks and BK channels.

Khavandi K, Baylie RA, Sugden SA, Ahmed M, Csato V, Eaton P, Hill-Eubanks DC, Bonev AD, Nelson MT, Greenstein AS.

Sci Signal. 2016 Oct 11;9(449):ra100. doi: 10.1126/scisignal.aaf6625.


Uncoupling of neurovascular communication after transient global cerebral ischemia is caused by impaired parenchymal smooth muscle Kir channel function.

Povlsen GK, Longden TA, Bonev AD, Hill-Eubanks DC, Nelson MT.

J Cereb Blood Flow Metab. 2016 Jul;36(7):1195-201. doi: 10.1177/0271678X16638350. Epub 2016 Apr 6.


Traumatic Brain Injury Causes Endothelial Dysfunction in the Systemic Microcirculation through Arginase-1-Dependent Uncoupling of Endothelial Nitric Oxide Synthase.

Villalba N, Sackheim AM, Nunez IA, Hill-Eubanks DC, Nelson MT, Wellman GC, Freeman K.

J Neurotrauma. 2017 Jan 1;34(1):192-203. doi: 10.1089/neu.2015.4340. Epub 2016 Apr 1.


Ion channel networks in the control of cerebral blood flow.

Longden TA, Hill-Eubanks DC, Nelson MT.

J Cereb Blood Flow Metab. 2016 Mar;36(3):492-512. doi: 10.1177/0271678X15616138. Epub 2015 Nov 9. Review.


The K+ channel KIR2.1 functions in tandem with proton influx to mediate sour taste transduction.

Ye W, Chang RB, Bushman JD, Tu YH, Mulhall EM, Wilson CE, Cooper AJ, Chick WS, Hill-Eubanks DC, Nelson MT, Kinnamon SC, Liman ER.

Proc Natl Acad Sci U S A. 2016 Jan 12;113(2):E229-38. doi: 10.1073/pnas.1514282112. Epub 2015 Dec 1.


Orchestrating Ca2+ influx through Ca(V)1.2 and Ca(V)3.x channels in human cerebral arteries.

Collier DM, Hill-Eubanks DC, Nelson MT.

J Gen Physiol. 2015 Jun;145(6):481-3. doi: 10.1085/jgp.201511411. No abstract available.


Potassium channelopathy-like defect underlies early-stage cerebrovascular dysfunction in a genetic model of small vessel disease.

Dabertrand F, Krøigaard C, Bonev AD, Cognat E, Dalsgaard T, Domenga-Denier V, Hill-Eubanks DC, Brayden JE, Joutel A, Nelson MT.

Proc Natl Acad Sci U S A. 2015 Feb 17;112(7):E796-805. doi: 10.1073/pnas.1420765112. Epub 2015 Feb 2.


Vascular TRP channels: performing under pressure and going with the flow.

Hill-Eubanks DC, Gonzales AL, Sonkusare SK, Nelson MT.

Physiology (Bethesda). 2014 Sep;29(5):343-60. doi: 10.1152/physiol.00009.2014. Review.


AKAP150-dependent cooperative TRPV4 channel gating is central to endothelium-dependent vasodilation and is disrupted in hypertension.

Sonkusare SK, Dalsgaard T, Bonev AD, Hill-Eubanks DC, Kotlikoff MI, Scott JD, Santana LF, Nelson MT.

Sci Signal. 2014 Jul 8;7(333):ra66. doi: 10.1126/scisignal.2005052.


A PLCγ1-dependent, force-sensitive signaling network in the myogenic constriction of cerebral arteries.

Gonzales AL, Yang Y, Sullivan MN, Sanders L, Dabertrand F, Hill-Eubanks DC, Nelson MT, Earley S.

Sci Signal. 2014 May 27;7(327):ra49. doi: 10.1126/scisignal.2004732.


Stress-induced glucocorticoid signaling remodels neurovascular coupling through impairment of cerebrovascular inwardly rectifying K+ channel function.

Longden TA, Dabertrand F, Hill-Eubanks DC, Hammack SE, Nelson MT.

Proc Natl Acad Sci U S A. 2014 May 20;111(20):7462-7. doi: 10.1073/pnas.1401811111. Epub 2014 May 7.


TRPV4 channels stimulate Ca2+-induced Ca2+ release in astrocytic endfeet and amplify neurovascular coupling responses.

Dunn KM, Hill-Eubanks DC, Liedtke WB, Nelson MT.

Proc Natl Acad Sci U S A. 2013 Apr 9;110(15):6157-62. doi: 10.1073/pnas.1216514110. Epub 2013 Mar 25.


Prostaglandin E2, a postulated astrocyte-derived neurovascular coupling agent, constricts rather than dilates parenchymal arterioles.

Dabertrand F, Hannah RM, Pearson JM, Hill-Eubanks DC, Brayden JE, Nelson MT.

J Cereb Blood Flow Metab. 2013 Apr;33(4):479-82. doi: 10.1038/jcbfm.2013.9. Epub 2013 Feb 6.


Elementary Ca2+ signals through endothelial TRPV4 channels regulate vascular function.

Sonkusare SK, Bonev AD, Ledoux J, Liedtke W, Kotlikoff MI, Heppner TJ, Hill-Eubanks DC, Nelson MT.

Science. 2012 May 4;336(6081):597-601. doi: 10.1126/science.1216283.


Calcium signaling in smooth muscle.

Hill-Eubanks DC, Werner ME, Heppner TJ, Nelson MT.

Cold Spring Harb Perspect Biol. 2011 Sep 1;3(9):a004549. doi: 10.1101/cshperspect.a004549. Review.


Local elementary purinergic-induced Ca2+ transients: from optical mapping of nerve activity to local Ca2+ signaling networks.

Hill-Eubanks DC, Werner ME, Nelson MT.

J Gen Physiol. 2010 Aug;136(2):149-54. doi: 10.1085/jgp.201010402. No abstract available.


NFATc3 regulates BK channel function in murine urinary bladder smooth muscle.

Layne JJ, Werner ME, Hill-Eubanks DC, Nelson MT.

Am J Physiol Cell Physiol. 2008 Sep;295(3):C611-23. doi: 10.1152/ajpcell.00435.2007. Epub 2008 Jun 25.


Nuclear factor of activated T cells and serum response factor cooperatively regulate the activity of an alpha-actin intronic enhancer.

Gonzalez Bosc LV, Layne JJ, Nelson MT, Hill-Eubanks DC.

J Biol Chem. 2005 Jul 15;280(28):26113-20. Epub 2005 Apr 27.


Intraluminal pressure is a stimulus for NFATc3 nuclear accumulation: role of calcium, endothelium-derived nitric oxide, and cGMP-dependent protein kinase.

Gonzalez Bosc LV, Wilkerson MK, Bradley KN, Eckman DM, Hill-Eubanks DC, Nelson MT.

J Biol Chem. 2004 Mar 12;279(11):10702-9. Epub 2003 Dec 19.


Constitutively elevated nuclear export activity opposes Ca2+-dependent NFATc3 nuclear accumulation in vascular smooth muscle: role of JNK2 and Crm-1.

Gomez MF, Bosc LV, Stevenson AS, Wilkerson MK, Hill-Eubanks DC, Nelson MT.

J Biol Chem. 2003 Nov 21;278(47):46847-53. Epub 2003 Sep 3.


NFAT regulation in smooth muscle.

Hill-Eubanks DC, Gomez MF, Stevenson AS, Nelson MT.

Trends Cardiovasc Med. 2003 Feb;13(2):56-62. Review.


Opposing actions of inositol 1,4,5-trisphosphate and ryanodine receptors on nuclear factor of activated T-cells regulation in smooth muscle.

Gomez MF, Stevenson AS, Bonev AD, Hill-Eubanks DC, Nelson MT.

J Biol Chem. 2002 Oct 4;277(40):37756-64. Epub 2002 Jul 26.


NFAT4 movement in native smooth muscle. A role for differential Ca(2+) signaling.

Stevenson AS, Gomez MF, Hill-Eubanks DC, Nelson MT.

J Biol Chem. 2001 May 4;276(18):15018-24. Epub 2001 Feb 7.


Differential proteolytic activation of factor VIII-von Willebrand factor complex by thrombin.

Hill-Eubanks DC, Parker CG, Lollar P.

Proc Natl Acad Sci U S A. 1989 Sep;86(17):6508-12.


Association of the factor VIII light chain with von Willebrand factor.

Lollar P, Hill-Eubanks DC, Parker CG.

J Biol Chem. 1988 Jul 25;263(21):10451-5.

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