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Urological complications of obesity and diabetes in males and females of three mouse models: temporal manifestations.

Kim AK, Hamadani C, Zeidel ML, Hill WG.

Am J Physiol Renal Physiol. 2020 Jan 1;318(1):F160-F174. doi: 10.1152/ajprenal.00207.2019. Epub 2019 Nov 4.


Targetable purinergic receptors P2Y12 and A2b antagonistically regulate bladder function.

Hao Y, Wang L, Chen H, Hill WG, Robson SC, Zeidel ML, Yu W.

JCI Insight. 2019 Aug 22;4(16). pii: 122112. doi: 10.1172/jci.insight.122112.


Students', colleagues' and research partners' experience about work and accomplishments from collaborating with Robin Thompson.

Hickey J, Hill WG, Blasco A, Cameron N, Cullis B, McGuirk B, Mäntysaari E, Ruane J, Simm G, Veerkamp R, Visscher PM, Wray NR.

J Anim Breed Genet. 2019 Jul;136(4):301-309. doi: 10.1111/jbg.12418. No abstract available.


Effect of heterogeneity in recombination rate on variation in realised relationship.

White IMS, Hill WG.

Heredity (Edinb). 2020 Jan;124(1):28-36. doi: 10.1038/s41437-019-0241-z. Epub 2019 Jun 20.


Publisher Correction: Selective effects of heterozygous protein-truncating variants.

Charlesworth B, Hill WG.

Nat Genet. 2019 Jan;51(1):196. doi: 10.1038/s41588-018-0325-3.


Selective effects of heterozygous protein-truncating variants.

Charlesworth B, Hill WG.

Nat Genet. 2019 Jan;51(1):2. doi: 10.1038/s41588-018-0291-9. No abstract available. Erratum in: Nat Genet. 2018 Dec 12;:.


Void spot assay: recommendations on the use of a simple micturition assay for mice.

Hill WG, Zeidel ML, Bjorling DE, Vezina CM.

Am J Physiol Renal Physiol. 2018 Nov 1;315(5):F1422-F1429. doi: 10.1152/ajprenal.00350.2018. Epub 2018 Aug 29. Review.


Void spot assay procedural optimization and software for rapid and objective quantification of rodent voiding function, including overlapping urine spots.

Wegner KA, Abler LL, Oakes SR, Mehta GS, Ritter KE, Hill WG, Zwaans BM, Lamb LE, Wang Z, Bjorling DE, Ricke WA, Macoska J, Marker PC, Southard-Smith EM, Eliceiri KW, Vezina CM.

Am J Physiol Renal Physiol. 2018 Oct 1;315(4):F1067-F1080. doi: 10.1152/ajprenal.00245.2018. Epub 2018 Jul 4.


One Hundred Years of Linkage Disequilibrium.

Sved JA, Hill WG.

Genetics. 2018 Jul;209(3):629-636. doi: 10.1534/genetics.118.300642.


Mouse urothelial genes associated with voiding behavior changes after ovariectomy and bladder lipopolysaccharide exposure.

Acevedo-Alvarez M, Yeh J, Alvarez-Lugo L, Lu M, Sukumar N, Hill WG, Chai TC.

Neurourol Urodyn. 2018 Nov;37(8):2398-2405. doi: 10.1002/nau.23592. Epub 2018 Apr 23.


Contributions to quantitative genetic models by Yule and by Weinberg prior to Fisher 1918.

Hill WG.

J Anim Breed Genet. 2018 Apr;135(2):93-94. doi: 10.1111/jbg.12320. No abstract available.


Role of P2X4 Receptor in Mouse Voiding Function.

Yu W, Hill WG, Robson SC, Zeidel ML.

Sci Rep. 2018 Jan 30;8(1):1838. doi: 10.1038/s41598-018-20216-4.


Evaluating the voiding spot assay in mice: a simple method with complex environmental interactions.

Chen H, Zhang L, Hill WG, Yu W.

Am J Physiol Renal Physiol. 2017 Dec 1;313(6):F1274-F1280. doi: 10.1152/ajprenal.00318.2017. Epub 2017 Aug 23.


Effect of filling rate on cystometric parameters in young and middle aged mice.

Kim AK, Hill WG.

Bladder (San Franc). 2017;4(1). pii: e28. doi: 10.14440/bladder.2017.88. Epub 2017 Feb 27.


Special K: once the fun is over an EMT arrives for the bladder.

Hill WG, Yu W.

Am J Physiol Renal Physiol. 2017 Dec 1;313(6):F1179-F1180. doi: 10.1152/ajprenal.00239.2017. Epub 2017 May 24. No abstract available.


"Conversion" of epistatic into additive genetic variance in finite populations and possible impact on long-term selection response.

Hill WG.

J Anim Breed Genet. 2017 Jun;134(3):196-201. doi: 10.1111/jbg.12270. Review.


Stage- and subunit-specific functions of polycomb repressive complex 2 in bladder urothelial formation and regeneration.

Guo C, Balsara ZR, Hill WG, Li X.

Development. 2017 Feb 1;144(3):400-408. doi: 10.1242/dev.143958. Epub 2017 Jan 3.


Oxidative costs of reproduction in mouse strains selected for different levels of food intake and which differ in reproductive performance.

Jothery AH, Vaanholt LM, Mody N, Arnous A, Lykkesfeldt J, Bünger L, Hill WG, Mitchell SE, Allison DB, Speakman JR.

Sci Rep. 2016 Nov 14;6:36353. doi: 10.1038/srep36353.


Is Continued Genetic Improvement of Livestock Sustainable?

Hill WG.

Genetics. 2016 Mar;202(3):877-81. doi: 10.1534/genetics.115.186650.


Aging Research Using Mouse Models.

Ackert-Bicknell CL, Anderson LC, Sheehan S, Hill WG, Chang B, Churchill GA, Chesler EJ, Korstanje R, Peters LL.

Curr Protoc Mouse Biol. 2015 Jun 1;5(2):95-133. doi: 10.1002/9780470942390.mo140195.


Evaluation of voiding assays in mice: impact of genetic strains and sex.

Bjorling DE, Wang Z, Vezina CM, Ricke WA, Keil KP, Yu W, Guo L, Zeidel ML, Hill WG.

Am J Physiol Renal Physiol. 2015 Jun 15;308(12):F1369-78. doi: 10.1152/ajprenal.00072.2015. Epub 2015 Apr 22.


Expected influence of linkage disequilibrium on genetic variance caused by dominance and epistasis on quantitative traits.

Hill WG, Mäki-Tanila A.

J Anim Breed Genet. 2015 Apr;132(2):176-86. doi: 10.1111/jbg.12140.


Dominance genetic variation contributes little to the missing heritability for human complex traits.

Zhu Z, Bakshi A, Vinkhuyzen AA, Hemani G, Lee SH, Nolte IM, van Vliet-Ostaptchouk JV, Snieder H; LifeLines Cohort Study, Esko T, Milani L, Mägi R, Metspalu A, Hill WG, Weir BS, Goddard ME, Visscher PM, Yang J.

Am J Hum Genet. 2015 Mar 5;96(3):377-85. doi: 10.1016/j.ajhg.2015.01.001. Epub 2015 Feb 12.


New impetus for innovation in benign urology.

Hill WG.

Am J Physiol Renal Physiol. 2015 Apr 15;308(8):F797-8. doi: 10.1152/ajprenal.00021.2015. Epub 2015 Feb 11. No abstract available.


Heritable environmental variance causes nonlinear relationships between traits: application to birth weight and stillbirth of pigs.

Mulder HA, Hill WG, Knol EF.

Genetics. 2015 Apr;199(4):1255-69. doi: 10.1534/genetics.114.173070. Epub 2015 Jan 27.


Limits to sustained energy intake. XXII. Reproductive performance of two selected mouse lines with different thermal conductance.

Al Jothery AH, Król E, Hawkins J, Chetoui A, Saint-Lambert A, Gamo Y, Shaw SC, Valencak T, Bünger L, Hill WG, Vaanholt LM, Hambly C, Speakman JR.

J Exp Biol. 2014 Oct 15;217(Pt 20):3718-32. doi: 10.1242/jeb.103705. Epub 2014 Sep 11.


ADP-induced bladder contractility is mediated by P2Y12 receptor and temporally regulated by ectonucleotidases and adenosine signaling.

Yu W, Sun X, Robson SC, Hill WG.

FASEB J. 2014 Dec;28(12):5288-98. doi: 10.1096/fj.14-255885. Epub 2014 Sep 10.


Influence of gene interaction on complex trait variation with multilocus models.

Mäki-Tanila A, Hill WG.

Genetics. 2014 Sep;198(1):355-67. doi: 10.1534/genetics.114.165282. Epub 2014 Jul 1.


Control of urinary drainage and voiding.

Hill WG.

Clin J Am Soc Nephrol. 2015 Mar 6;10(3):480-92. doi: 10.2215/CJN.04520413. Epub 2014 Apr 17. Review.


Spontaneous voiding by mice reveals strain-specific lower urinary tract function to be a quantitative genetic trait.

Yu W, Ackert-Bicknell C, Larigakis JD, MacIver B, Steers WD, Churchill GA, Hill WG, Zeidel ML.

Am J Physiol Renal Physiol. 2014 Jun 1;306(11):F1296-307. doi: 10.1152/ajprenal.00074.2014. Epub 2014 Apr 9.


The action of stabilizing selection, mutation, and drift on epistatic quantitative traits.

Avila V, Pérez-Figueroa A, Caballero A, Hill WG, García-Dorado A, López-Fanjul C.

Evolution. 2014 Jul;68(7):1974-87. doi: 10.1111/evo.12413. Epub 2014 May 5.


Applications of population genetics to animal breeding, from wright, fisher and lush to genomic prediction.

Hill WG.

Genetics. 2014 Jan;196(1):1-16. doi: 10.1534/genetics.112.147850. Review.


Erratum to: On estimation of genetic variance within families using genome-wide identity-by-descent sharing.

Hill WG.

Genet Sel Evol. 2014 Oct 15;46:62. doi: 10.1186/s12711-014-0062-8. No abstract available.


Assumptions and properties of limiting pathway models for analysis of epistasis in complex traits.

Stringer S, Derks EM, Kahn RS, Hill WG, Wray NR.

PLoS One. 2013 Jul 30;8(7):e68913. doi: 10.1371/journal.pone.0068913. Print 2013.


Identification of pedigree relationship from genome sharing.

Hill WG, White IM.

G3 (Bethesda). 2013 Sep 4;3(9):1553-71. doi: 10.1534/g3.113.007500.


Lack of specificity shown by P2Y6 receptor antibodies.

Yu W, Hill WG.

Naunyn Schmiedebergs Arch Pharmacol. 2013 Oct;386(10):885-91. doi: 10.1007/s00210-013-0894-8. Epub 2013 Jun 22.


Loss of β1-integrin from urothelium results in overactive bladder and incontinence in mice: a mechanosensory rather than structural phenotype.

Kanasaki K, Yu W, von Bodungen M, Larigakis JD, Kanasaki M, Ayala de la Pena F, Kalluri R, Hill WG.

FASEB J. 2013 May;27(5):1950-61. doi: 10.1096/fj.12-223404. Epub 2013 Feb 8.


Extracellular UDP enhances P2X-mediated bladder smooth muscle contractility via P2Y(6) activation of the phospholipase C/inositol trisphosphate pathway.

Yu W, Sun X, Robson SC, Hill WG.

FASEB J. 2013 May;27(5):1895-903. doi: 10.1096/fj.12-219006. Epub 2013 Jan 29.


Variation in actual relationship among descendants of inbred individuals.

Hill WG, Weir BS.

Genet Res (Camb). 2012 Oct;94(5):267-74. doi: 10.1017/S0016672312000468.


Descriptive analysis of the respiratory health status of persons exposed to Libby amphibole asbestos.

Winters CA, Hill WG, Rowse K, Black B, Kuntz SW, Weinert C.

BMJ Open. 2012 Nov 21;2(6). pii: e001552. doi: 10.1136/bmjopen-2012-001552. Print 2012.


Twenty-five years of selection for improved leg health in purebred broiler lines and underlying genetic parameters.

Kapell DN, Hill WG, Neeteson AM, McAdam J, Koerhuis AN, Avendaño S.

Poult Sci. 2012 Dec;91(12):3032-43. doi: 10.3382/ps.2012-02578.


Cellular expression profile for interstitial cells of cajal in bladder - a cell often misidentified as myocyte or myofibroblast.

Yu W, Zeidel ML, Hill WG.

PLoS One. 2012;7(11):e48897. doi: 10.1371/journal.pone.0048897. Epub 2012 Nov 7.


Quantitative genetics in the genomics era.

Hill WG.

Curr Genomics. 2012 May;13(3):196-206. doi: 10.2174/138920212800543110.


FTO genotype is associated with phenotypic variability of body mass index.

Yang J, Loos RJ, Powell JE, Medland SE, Speliotes EK, Chasman DI, Rose LM, Thorleifsson G, Steinthorsdottir V, Mägi R, Waite L, Smith AV, Yerges-Armstrong LM, Monda KL, Hadley D, Mahajan A, Li G, Kapur K, Vitart V, Huffman JE, Wang SR, Palmer C, Esko T, Fischer K, Zhao JH, Demirkan A, Isaacs A, Feitosa MF, Luan J, Heard-Costa NL, White C, Jackson AU, Preuss M, Ziegler A, Eriksson J, Kutalik Z, Frau F, Nolte IM, Van Vliet-Ostaptchouk JV, Hottenga JJ, Jacobs KB, Verweij N, Goel A, Medina-Gomez C, Estrada K, Bragg-Gresham JL, Sanna S, Sidore C, Tyrer J, Teumer A, Prokopenko I, Mangino M, Lindgren CM, Assimes TL, Shuldiner AR, Hui J, Beilby JP, McArdle WL, Hall P, Haritunians T, Zgaga L, Kolcic I, Polasek O, Zemunik T, Oostra BA, Junttila MJ, Grönberg H, Schreiber S, Peters A, Hicks AA, Stephens J, Foad NS, Laitinen J, Pouta A, Kaakinen M, Willemsen G, Vink JM, Wild SH, Navis G, Asselbergs FW, Homuth G, John U, Iribarren C, Harris T, Launer L, Gudnason V, O'Connell JR, Boerwinkle E, Cadby G, Palmer LJ, James AL, Musk AW, Ingelsson E, Psaty BM, Beckmann JS, Waeber G, Vollenweider P, Hayward C, Wright AF, Rudan I, Groop LC, Metspalu A, Khaw KT, van Duijn CM, Borecki IB, Province MA, Wareham NJ, Tardif JC, Huikuri HV, Cupples LA, Atwood LD, Fox CS, Boehnke M, Collins FS, Mohlke KL, Erdmann J, Schunkert H, Hengstenberg C, Stark K, Lorentzon M, Ohlsson C, Cusi D, Staessen JA, Van der Klauw MM, Pramstaller PP, Kathiresan S, Jolley JD, Ripatti S, Jarvelin MR, de Geus EJ, Boomsma DI, Penninx B, Wilson JF, Campbell H, Chanock SJ, van der Harst P, Hamsten A, Watkins H, Hofman A, Witteman JC, Zillikens MC, Uitterlinden AG, Rivadeneira F, Zillikens MC, Kiemeney LA, Vermeulen SH, Abecasis GR, Schlessinger D, Schipf S, Stumvoll M, Tönjes A, Spector TD, North KE, Lettre G, McCarthy MI, Berndt SI, Heath AC, Madden PA, Nyholt DR, Montgomery GW, Martin NG, McKnight B, Strachan DP, Hill WG, Snieder H, Ridker PM, Thorsteinsdottir U, Stefansson K, Frayling TM, Hirschhorn JN, Goddard ME, Visscher PM.

Nature. 2012 Oct 11;490(7419):267-72. doi: 10.1038/nature11401. Epub 2012 Sep 16.


Genome-wide association analysis and genetic architecture of egg weight and egg uniformity in layer chickens.

Wolc A, Arango J, Settar P, Fulton JE, O'Sullivan NP, Preisinger R, Habier D, Fernando R, Garrick DJ, Hill WG, Dekkers JC.

Anim Genet. 2012 Jul;43 Suppl 1:87-96. doi: 10.1111/j.1365-2052.2012.02381.x.


Genetic parameters of egg defects and egg quality in layer chickens.

Wolc A, Arango J, Settar P, O'Sullivan NP, Olori VE, White IM, Hill WG, Dekkers JC.

Poult Sci. 2012 Jun;91(6):1292-8. doi: 10.3382/ps.2011-02130.


Assessing pleiotropy and its evolutionary consequences: pleiotropy is not necessarily limited, nor need it hinder the evolution of complexity.

Hill WG, Zhang XS.

Nat Rev Genet. 2012 Feb 21;13(4):296; author reply 296. doi: 10.1038/nrg2949-c1. No abstract available.


Genetic parameters of foot-pad dermatitis and body weight in purebred broiler lines in 2 contrasting environments.

Kapell DN, Hill WG, Neeteson AM, McAdam J, Koerhuis AN, Avendaño S.

Poult Sci. 2012 Mar;91(3):565-74. doi: 10.3382/ps.2011-01934.


Uroplakins do not restrict CO2 transport through urothelium.

Zocher F, Zeidel ML, Missner A, Sun TT, Zhou G, Liao Y, von Bodungen M, Hill WG, Meyers S, Pohl P, Mathai JC.

J Biol Chem. 2012 Mar 30;287(14):11011-7. doi: 10.1074/jbc.M112.339283. Epub 2012 Feb 7.

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