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Items: 1 to 50 of 71

1.

Structure-Activity Relationships of Wollamide Cyclic Hexapeptides with Activity against Drug-Resistant and Intracellular Mycobacterium tuberculosis.

Khalil ZG, Hill TA, De Leon Rodriguez LM, Lohman RJ, Hoang HN, Reiling N, Hillemann D, Brimble MA, Fairlie DP, Blumenthal A, Capon RJ.

Antimicrob Agents Chemother. 2019 Feb 26;63(3). pii: e01773-18. doi: 10.1128/AAC.01773-18. Print 2019 Mar.

PMID:
30602509
2.

Comparative transcriptomics and genomic patterns of discordance in Capsiceae (Solanaceae).

Spalink D, Stoffel K, Walden GK, Hulse-Kemp AM, Hill TA, Van Deynze A, Bohs L.

Mol Phylogenet Evol. 2018 Sep;126:293-302. doi: 10.1016/j.ympev.2018.04.030. Epub 2018 Apr 25.

PMID:
29702214
3.

Reference quality assembly of the 3.5-Gb genome of Capsicum annuum from a single linked-read library.

Hulse-Kemp AM, Maheshwari S, Stoffel K, Hill TA, Jaffe D, Williams SR, Weisenfeld N, Ramakrishnan S, Kumar V, Shah P, Schatz MC, Church DM, Van Deynze A.

Hortic Res. 2018 Jan 12;5:4. doi: 10.1038/s41438-017-0011-0. eCollection 2018.

4.

Regions Underlying Population Structure and the Genomics of Organ Size Determination in Capsicum annuum.

Hill TA, Chunthawodtiporn J, Ashrafi H, Stoffel K, Weir A, Van Deynze A.

Plant Genome. 2017 Nov;10(3). doi: 10.3835/plantgenome2017.03.0026.

5.

Contiguous hydrophobic and charged surface patches in short helix-constrained peptides drive cell permeability.

Perry SR, Hill TA, de Araujo AD, Hoang HN, Fairlie DP.

Org Biomol Chem. 2018 Jan 17;16(3):367-371. doi: 10.1039/c7ob02952g.

PMID:
29264603
6.

Reducing inhomogeneity in the dynamic properties of quantum dots via self-aligned plasmonic cavities.

Demory B, Hill TA, Teng CH, Deng H, Ku PC.

Nanotechnology. 2018 Jan 5;29(1):015201. doi: 10.1088/1361-6528/aa994c.

PMID:
29119951
7.

Scabies in babies.

Hill TA, Cohen B.

Pediatr Dermatol. 2017 Nov;34(6):690-694. doi: 10.1111/pde.13255. Epub 2017 Aug 22.

PMID:
28833468
8.

Disease Resistance to Multiple Fungal and Oomycete Pathogens Evaluated Using a Recombinant Inbred Line Population in Pepper.

Naegele RP, Granke LL, Fry J, Hill TA, Ashrafi H, Van Deynze A, Hausbeck MK.

Phytopathology. 2017 Dec;107(12):1522-1531. doi: 10.1094/PHYTO-02-17-0040-R. Epub 2017 Oct 2.

PMID:
28762287
9.

Downsizing Proto-oncogene cFos to Short Helix-Constrained Peptides That Bind Jun.

Baxter D, Perry SR, Hill TA, Kok WM, Zaccai NR, Brady RL, Fairlie DP, Mason JM.

ACS Chem Biol. 2017 Aug 18;12(8):2051-2061. doi: 10.1021/acschembio.7b00303. Epub 2017 Jun 21.

PMID:
28636317
10.

Biased Signaling by Agonists of Protease Activated Receptor 2.

Jiang Y, Yau MK, Kok WM, Lim J, Wu KC, Liu L, Hill TA, Suen JY, Fairlie DP.

ACS Chem Biol. 2017 May 19;12(5):1217-1226. doi: 10.1021/acschembio.6b01088. Epub 2017 Mar 14.

PMID:
28169521
11.

Pyrimidine-Based Inhibitors of Dynamin I GTPase Activity: Competitive Inhibition at the Pleckstrin Homology Domain.

Odell LR, Abdel-Hamid MK, Hill TA, Chau N, Young KA, Deane FM, Sakoff JA, Andersson S, Daniel JA, Robinson PJ, McCluskey A.

J Med Chem. 2017 Jan 12;60(1):349-361. doi: 10.1021/acs.jmedchem.6b01422. Epub 2016 Dec 20.

PMID:
27997171
12.

Helixconstraints and amino acid substitution in GLP-1 increase cAMP and insulin secretion but not beta-arrestin 2 signaling.

Plisson F, Hill TA, Mitchell JM, Hoang HN, de Araujo AD, Xu W, Cotterell A, Edmonds DJ, Stanton RV, Derksen DR, Loria PM, Griffith DA, Price DA, Liras S, Fairlie DP.

Eur J Med Chem. 2017 Feb 15;127:703-714. doi: 10.1016/j.ejmech.2016.10.044. Epub 2016 Oct 21.

PMID:
27823886
13.

Helix Nucleation by the Smallest Known α-Helix in Water.

Hoang HN, Driver RW, Beyer RL, Hill TA, D de Araujo A, Plisson F, Harrison RS, Goedecke L, Shepherd NE, Fairlie DP.

Angew Chem Int Ed Engl. 2016 Jul 11;55(29):8275-9. doi: 10.1002/anie.201602079. Epub 2016 May 25.

PMID:
27226426
14.

Flexibility versus Rigidity for Orally Bioavailable Cyclic Hexapeptides.

Nielsen DS, Lohman RJ, Hoang HN, Hill TA, Jones A, Lucke AJ, Fairlie DP.

Chembiochem. 2015 Nov 2;16(16):2289-93. doi: 10.1002/cbic.201500441. Epub 2015 Oct 7.

PMID:
26336864
15.

Short Hydrophobic Peptides with Cyclic Constraints Are Potent Glucagon-like Peptide-1 Receptor (GLP-1R) Agonists.

Hoang HN, Song K, Hill TA, Derksen DR, Edmonds DJ, Kok WM, Limberakis C, Liras S, Loria PM, Mascitti V, Mathiowetz AM, Mitchell JM, Piotrowski DW, Price DA, Stanton RV, Suen JY, Withka JM, Griffith DA, Fairlie DP.

J Med Chem. 2015 May 14;58(9):4080-5. doi: 10.1021/acs.jmedchem.5b00166. Epub 2015 Apr 16.

PMID:
25839426
16.

Helix-constrained nociceptin peptides are potent agonists and antagonists of ORL-1 and nociception.

Lohman RJ, Harrison RS, Ruiz-Gómez G, Hoang HN, Shepherd NE, Chow S, Hill TA, Madala PK, Fairlie DP.

Vitam Horm. 2015;97:1-55. doi: 10.1016/bs.vh.2014.10.001. Epub 2015 Jan 14. Review.

PMID:
25677767
17.

Cyclic Penta- and Hexaleucine Peptides without N-Methylation Are Orally Absorbed.

Hill TA, Lohman RJ, Hoang HN, Nielsen DS, Scully CC, Kok WM, Liu L, Lucke AJ, Stoermer MJ, Schroeder CI, Chaousis S, Colless B, Bernhardt PV, Edmonds DJ, Griffith DA, Rotter CJ, Ruggeri RB, Price DA, Liras S, Craik DJ, Fairlie DP.

ACS Med Chem Lett. 2014 Aug 4;5(10):1148-51. doi: 10.1021/ml5002823. eCollection 2014 Oct 9.

18.

Constraining cyclic peptides to mimic protein structure motifs.

Hill TA, Shepherd NE, Diness F, Fairlie DP.

Angew Chem Int Ed Engl. 2014 Nov 24;53(48):13020-41. doi: 10.1002/anie.201401058. Epub 2014 Oct 6. Review.

PMID:
25287434
19.

Improving on nature: making a cyclic heptapeptide orally bioavailable.

Nielsen DS, Hoang HN, Lohman RJ, Hill TA, Lucke AJ, Craik DJ, Edmonds DJ, Griffith DA, Rotter CJ, Ruggeri RB, Price DA, Liras S, Fairlie DP.

Angew Chem Int Ed Engl. 2014 Nov 3;53(45):12059-63. doi: 10.1002/anie.201405364. Epub 2014 Sep 12.

PMID:
25219505
20.

Multistate foodborne disease outbreaks associated with raw tomatoes, United States, 1990-2010: a recurring public health problem.

Bennett SD, Littrell KW, Hill TA, Mahovic M, Behravesh CB.

Epidemiol Infect. 2015 May;143(7):1352-9. doi: 10.1017/S0950268814002167. Epub 2014 Aug 28.

PMID:
25167220
21.

Comparative α-helicity of cyclic pentapeptides in water.

de Araujo AD, Hoang HN, Kok WM, Diness F, Gupta P, Hill TA, Driver RW, Price DA, Liras S, Fairlie DP.

Angew Chem Int Ed Engl. 2014 Jul 1;53(27):6965-9. doi: 10.1002/anie.201310245. Epub 2014 May 14.

PMID:
24828311
22.

QTL mapping of fruit rot resistance to the plant pathogen Phytophthora capsici in a recombinant inbred line Capsicum annuum population.

Naegele RP, Ashrafi H, Hill TA, Chin-Wo SR, Van Deynze AE, Hausbeck MK.

Phytopathology. 2014 May;104(5):479-83. doi: 10.1094/PHYTO-05-13-0143-R.

23.

A novel class of anticancer compounds targets the actin cytoskeleton in tumor cells.

Stehn JR, Haass NK, Bonello T, Desouza M, Kottyan G, Treutlein H, Zeng J, Nascimento PR, Sequeira VB, Butler TL, Allanson M, Fath T, Hill TA, McCluskey A, Schevzov G, Palmer SJ, Hardeman EC, Winlaw D, Reeve VE, Dixon I, Weninger W, Cripe TP, Gunning PW.

Cancer Res. 2013 Aug 15;73(16):5169-82. doi: 10.1158/0008-5472.CAN-12-4501. Erratum in: Cancer Res. 2013 Oct 1;73(19):6094.

24.

Pyrimidyn compounds: dual-action small molecule pyrimidine-based dynamin inhibitors.

McGeachie AB, Odell LR, Quan A, Daniel JA, Chau N, Hill TA, Gorgani NN, Keating DJ, Cousin MA, van Dam EM, Mariana A, Whiting A, Perera S, Novelle A, Young KA, Deane FM, Gilbert J, Sakoff JA, Chircop M, McCluskey A, Robinson PJ.

ACS Chem Biol. 2013 Jul 19;8(7):1507-18. doi: 10.1021/cb400137p. Epub 2013 May 30.

PMID:
23642287
25.

Truncated and helix-constrained peptides with high affinity and specificity for the cFos coiled-coil of AP-1.

Rao T, Ruiz-Gómez G, Hill TA, Hoang HN, Fairlie DP, Mason JM.

PLoS One. 2013;8(3):e59415. doi: 10.1371/journal.pone.0059415. Epub 2013 Mar 27.

26.

Characterization of Capsicum annuum genetic diversity and population structure based on parallel polymorphism discovery with a 30K unigene Pepper GeneChip.

Hill TA, Ashrafi H, Reyes-Chin-Wo S, Yao J, Stoffel K, Truco MJ, Kozik A, Michelmore RW, Van Deynze A.

PLoS One. 2013;8(2):e56200. doi: 10.1371/journal.pone.0056200. Epub 2013 Feb 8.

27.

Identification of QTLs for capsaicinoids, fruit quality, and plant architecture-related traits in an interspecific Capsicum RIL population.

Yarnes SC, Ashrafi H, Reyes-Chin-Wo S, Hill TA, Stoffel KM, Van Deynze A.

Genome. 2013 Jan;56(1):61-74. doi: 10.1139/gen-2012-0083. Epub 2013 Jan 1.

PMID:
23379339
28.

Observations on variation in the ultrastructure of the proximal testicular ducts of the Ground Skink, Scincella lateralis (Reptilia: Squamata).

Sever DM, Rheubert JL, Hill TA, Siegel DS.

J Morphol. 2013 Apr;274(4):429-46. doi: 10.1002/jmor.20104. Epub 2012 Nov 28.

PMID:
23192894
29.

Multistate outbreak of Salmonella serotype Typhimurium infections associated with consumption of restaurant tomatoes, USA, 2006: hypothesis generation through case exposures in multiple restaurant clusters.

Behravesh CB, Blaney D, Medus C, Bidol SA, Phan Q, Soliva S, Daly ER, Smith K, Miller B, Taylor T Jr, Nguyen T, Perry C, Hill TA, Fogg N, Kleiza A, Moorhead D, Al-Khaldi S, Braden C, Lynch MF.

Epidemiol Infect. 2012 Nov;140(11):2053-61. Epub 2012 Jan 20.

PMID:
22261286
30.

What a difference one person can make: a tribute to Mary P. Lovato.

Burhansstipanov L, O'Donnell J, Paisano R, Krebs LU, Kaur JS, Hill TA, Lovato MP.

J Cancer Educ. 2011 Sep;26(3):591-3. doi: 10.1007/s13187-011-0236-9. No abstract available.

PMID:
21681435
31.

Novel helix-constrained nociceptin derivatives are potent agonists and antagonists of ERK phosphorylation and thermal analgesia in mice.

Harrison RS, Ruiz-Gómez G, Hill TA, Chow SY, Shepherd NE, Lohman RJ, Abbenante G, Hoang HN, Fairlie DP.

J Med Chem. 2010 Dec 9;53(23):8400-8. doi: 10.1021/jm101139f. Epub 2010 Nov 10.

PMID:
21067234
32.

The antiplasmodial activity of norcantharidin analogs.

Bajsa J, McCluskey A, Gordon CP, Stewart SG, Hill TA, Sahu R, Duke SO, Tekwani BL.

Bioorg Med Chem Lett. 2010 Nov 15;20(22):6688-95. doi: 10.1016/j.bmcl.2010.09.004. Epub 2010 Sep 7.

PMID:
20888768
33.

Downsizing human, bacterial, and viral proteins to short water-stable alpha helices that maintain biological potency.

Harrison RS, Shepherd NE, Hoang HN, Ruiz-Gómez G, Hill TA, Driver RW, Desai VS, Young PR, Abbenante G, Fairlie DP.

Proc Natl Acad Sci U S A. 2010 Jun 29;107(26):11686-91. doi: 10.1073/pnas.1002498107. Epub 2010 Jun 11.

34.

Iminochromene inhibitors of dynamins I and II GTPase activity and endocytosis.

Hill TA, Mariana A, Gordon CP, Odell LR, Robertson MJ, McGeachie AB, Chau N, Daniel JA, Gorgani NN, Robinson PJ, McCluskey A.

J Med Chem. 2010 May 27;53(10):4094-102. doi: 10.1021/jm100119c.

PMID:
20426422
35.

Update 1 of: Beta-strand mimetics.

Loughlin WA, Tyndall JD, Glenn MP, Hill TA, Fairlie DP.

Chem Rev. 2010 Jun 9;110(6):PR32-69. doi: 10.1021/cr900395y. Epub 2010 Apr 12. Review. No abstract available.

PMID:
20384343
36.

Inhibition of dynamin mediated endocytosis by the dynoles--synthesis and functional activity of a family of indoles.

Hill TA, Gordon CP, McGeachie AB, Venn-Brown B, Odell LR, Chau N, Quan A, Mariana A, Sakoff JA, Chircop M, Robinson PJ, McCluskey A.

J Med Chem. 2009 Jun 25;52(12):3762-73. doi: 10.1021/jm900036m.

PMID:
19459681
37.

Norcantharidin analogues: synthesis, anticancer activity and protein phosphatase 1 and 2A inhibition.

Hill TA, Stewart SG, Gordon CP, Ackland SP, Gilbert J, Sauer B, Sakoff JA, McCluskey A.

ChemMedChem. 2008 Dec;3(12):1878-92. doi: 10.1002/cmdc.200800192.

PMID:
19025735
38.

Intracellular cytokine profiles and T cell activation in pulmonary sarcoidosis.

Hill TA, Lightman S, Pantelidis P, Abdallah A, Spagnolo P, du Bois RM.

Cytokine. 2008 Jun;42(3):289-92. doi: 10.1016/j.cyto.2008.03.014. Epub 2008 May 15.

PMID:
18485728
39.

An Arabidopsis F-box protein acts as a transcriptional co-factor to regulate floral development.

Chae E, Tan QK, Hill TA, Irish VF.

Development. 2008 Apr;135(7):1235-45. doi: 10.1242/dev.015842. Epub 2008 Feb 20.

40.

The nuclear genome of Brachypodium distachyon: analysis of BAC end sequences.

Huo N, Lazo GR, Vogel JP, You FM, Ma Y, Hayden DM, Coleman-Derr D, Hill TA, Dvorak J, Anderson OD, Luo MC, Gu YQ.

Funct Integr Genomics. 2008 May;8(2):135-47. Epub 2007 Nov 6.

PMID:
17985162
41.

Synthesis and biological evaluation of norcantharidin analogues: towards PP1 selectivity.

Stewart SG, Hill TA, Gilbert J, Ackland SP, Sakoff JA, McCluskey A.

Bioorg Med Chem. 2007 Dec 1;15(23):7301-10. Epub 2007 Aug 24.

PMID:
17870547
42.

Norcantharimides, synthesis and anticancer activity: Synthesis of new norcantharidin analogues and their anticancer evaluation.

Hill TA, Stewart SG, Ackland SP, Gilbert J, Sauer B, Sakoff JA, McCluskey A.

Bioorg Med Chem. 2007 Sep 15;15(18):6126-34. Epub 2007 Jun 20.

PMID:
17606377
43.

Recurrent multistate outbreak of Salmonella Newport associated with tomatoes from contaminated fields, 2005.

Greene SK, Daly ER, Talbot EA, Demma LJ, Holzbauer S, Patel NJ, Hill TA, Walderhaug MO, Hoekstra RM, Lynch MF, Painter JA.

Epidemiol Infect. 2008 Feb;136(2):157-65. Epub 2007 May 16.

44.

Heterocyclic substituted cantharidin and norcantharidin analogues--synthesis, protein phosphatase (1 and 2A) inhibition, and anti-cancer activity.

Hill TA, Stewart SG, Sauer B, Gilbert J, Ackland SP, Sakoff JA, McCluskey A.

Bioorg Med Chem Lett. 2007 Jun 15;17(12):3392-7. Epub 2007 Apr 2.

PMID:
17451951
45.

Arabidopsis SHORT INTEGUMENTS 2 is a mitochondrial DAR GTPase.

Hill TA, Broadhvest J, Kuzoff RK, Gasser CS.

Genetics. 2006 Oct;174(2):707-18. Epub 2006 Jul 18.

46.

ABERRANT TESTA SHAPE encodes a KANADI family member, linking polarity determination to separation and growth of Arabidopsis ovule integuments.

McAbee JM, Hill TA, Skinner DJ, Izhaki A, Hauser BA, Meister RJ, Venugopala Reddy G, Meyerowitz EM, Bowman JL, Gasser CS.

Plant J. 2006 May;46(3):522-31.

47.

Long chain amines and long chain ammonium salts as novel inhibitors of dynamin GTPase activity.

Hill TA, Odell LR, Quan A, Abagyan R, Ferguson G, Robinson PJ, McCluskey A.

Bioorg Med Chem Lett. 2004 Jun 21;14(12):3275-8.

PMID:
15149689
48.

Regulation of ovule development.

Skinner DJ, Hill TA, Gasser CS.

Plant Cell. 2004;16 Suppl:S32-45. Epub 2004 May 6. Review. No abstract available.

49.

Capillary-channeled polymer fibers as stationary phases in liquid chromatography separations.

Marcus RK, Davis WC, Knippel BC, LaMotte L, Hill TA, Perahia D, Jenkins JD.

J Chromatogr A. 2003 Jan 31;986(1):17-31.

PMID:
12585319
50.

Radio frequency glow discharge optical emission spectroscopy: a new weapon in the depth profiling arsenal.

Marcus RK, Anfone AB, Luesaiwong W, Hill TA, Perahia D, Shimizu K.

Anal Bioanal Chem. 2002 Aug;373(7):656-63. Epub 2002 Jun 26.

PMID:
12185579

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