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Assessment of Combined Nivolumab and Bevacizumab in Relapsed Ovarian Cancer: A Phase 2 Clinical Trial.

Liu JF, Herold C, Gray KP, Penson RT, Horowitz N, Konstantinopoulos PA, Castro CM, Hill SJ, Curtis J, Luo W, Matulonis UA, Cannistra SA, Dizon DS.

JAMA Oncol. 2019 Oct 10. doi: 10.1001/jamaoncol.2019.3343. [Epub ahead of print]


The effect of two selective A1 -receptor agonists and the bitopic ligand VCP746 on heart rate and regional vascular conductance in conscious rats.

Cooper SL, March J, Sabbatini AR, Hill SJ, Jörg M, Scammells PJ, Woolard J.

Br J Pharmacol. 2019 Oct 9. doi: 10.1111/bph.14870. [Epub ahead of print]


NanoBiT Complementation to Monitor Agonist-Induced Adenosine A1 Receptor Internalization.

Soave M, Kellam B, Woolard J, Briddon SJ, Hill SJ.

SLAS Discov. 2019 Oct 4:2472555219880475. doi: 10.1177/2472555219880475. [Epub ahead of print]


Optimised insert design for improved single-molecule imaging and quantification through CRISPR-Cas9 mediated knock-in.

Khan AO, White CW, Pike JA, Yule J, Slater A, Hill SJ, Poulter NS, Thomas SG, Morgan NV.

Sci Rep. 2019 Oct 2;9(1):14219. doi: 10.1038/s41598-019-50733-9.


The effect of EMAT coil geometry on the Rayleigh wave frequency behaviour.

Thring CB, Hill SJ, Dixon S, Edwards RS.

Ultrasonics. 2019 Jun 12;99:105945. doi: 10.1016/j.ultras.2019.06.007. [Epub ahead of print]


Predictive Potential of Head and Neck Squamous Cell Carcinoma Organoids.

Hill SJ, D'Andrea AD.

Cancer Discov. 2019 Jul;9(7):828-830. doi: 10.1158/2159-8290.CD-19-0527.


Comparison of the ligand-binding properties of fluorescent VEGF-A isoforms to VEGF receptor 2 in living cells and membrane preparations using NanoBRET.

Peach CJ, Kilpatrick LE, Woolard J, Hill SJ.

Br J Pharmacol. 2019 Sep;176(17):3220-3235. doi: 10.1111/bph.14755. Epub 2019 Jul 15.


Probe dependency in the determination of ligand binding kinetics at a prototypical G protein-coupled receptor.

Bosma R, Stoddart LA, Georgi V, Bouzo-Lorenzo M, Bushby N, Inkoom L, Waring MJ, Briddon SJ, Vischer HF, Sheppard RJ, Fernández-Montalván A, Hill SJ, Leurs R.

Sci Rep. 2019 May 27;9(1):7906. doi: 10.1038/s41598-019-44025-5.


Adenosine and Forskolin Inhibit Platelet Aggregation by Collagen but not the Proximal Signalling Events.

Clark JC, Kavanagh DM, Watson S, Pike JA, Andrews RK, Gardiner EE, Poulter NS, Hill SJ, Watson SP.

Thromb Haemost. 2019 Jul;119(7):1124-1137. doi: 10.1055/s-0039-1688788. Epub 2019 May 26.


Context-dependent signalling of CXC chemokine receptor 4 (CXCR4) and atypical chemokine receptor 3 (ACKR3).

Heuninck J, Perpina Viciano C, Işbilir A, Caspar B, Capoferri D, Briddon SJ, Durroux T, Hill SJ, Lohse MJ, Milligan G, Pin JP, Hoffmann C.

Mol Pharmacol. 2019 May 15. pii: mol.118.115477. doi: 10.1124/mol.118.115477. [Epub ahead of print]


Selecting, refining and identifying priority Cochrane Reviews in health communication and participation in partnership with consumers and other stakeholders.

Synnot AJ, Tong A, Bragge P, Lowe D, Nunn JS, O'Sullivan M, Horvat L, Kay D, Ghersi D, McDonald S, Poole N, Bourke N, Lannin NA, Vadasz D, Oliver S, Carey K, Hill SJ.

Health Res Policy Syst. 2019 Apr 29;17(1):45. doi: 10.1186/s12961-019-0444-z.


Complex Formation between VEGFR2 and the β2-Adrenoceptor.

Kilpatrick LE, Alcobia DC, White CW, Peach CJ, Glenn JR, Zimmerman K, Kondrashov A, Pfleger KDG, Ohana RF, Robers MB, Wood KV, Sloan EK, Woolard J, Hill SJ.

Cell Chem Biol. 2019 Jun 20;26(6):830-841.e9. doi: 10.1016/j.chembiol.2019.02.014. Epub 2019 Apr 4.


A live cell NanoBRET binding assay allows the study of ligand-binding kinetics to the adenosine A3 receptor.

Bouzo-Lorenzo M, Stoddart LA, Xia L, IJzerman AP, Heitman LH, Briddon SJ, Hill SJ.

Purinergic Signal. 2019 Jun;15(2):139-153. doi: 10.1007/s11302-019-09650-9. Epub 2019 Mar 27.


CXCR4/ACKR3 phosphorylation and recruitment of interacting proteins: key mechanisms regulating their functional status.

Fumagalli A, Zarca A, Neves M, Caspar B, Hill SJ, Mayor F, Smit MJ, Marin P.

Mol Pharmacol. 2019 Mar 5. pii: mol.118.115360. doi: 10.1124/mol.118.115360. [Epub ahead of print]


Binding kinetics of ligands acting at GPCRs.

Sykes DA, Stoddart LA, Kilpatrick LE, Hill SJ.

Mol Cell Endocrinol. 2019 Apr 5;485:9-19. doi: 10.1016/j.mce.2019.01.018. Epub 2019 Feb 8. Review.


Probe dependence of allosteric enhancers on the binding affinity of adenosine A1 -receptor agonists at rat and human A1 -receptors measured using NanoBRET.

Cooper SL, Soave M, Jörg M, Scammells PJ, Woolard J, Hill SJ.

Br J Pharmacol. 2019 Apr;176(7):864-878. doi: 10.1111/bph.14575. Epub 2019 Mar 6.


Producing an evidence-based treatment information website in partnership with people affected by multiple sclerosis.

Synnot AJ, Hawkins M, Merner BA, Summers MP, Filippini G, Osborne RH, Shapland SDP, Cherry CL, Stuckey R, Milne CA, Mosconi P, Colombo C, Hill SJ.

Health Sci Rep. 2018 Mar 6;1(3):e24. doi: 10.1002/hsr2.24. eCollection 2018 Mar.


The voting experience and beliefs about ballot secrecy.

Dowling CM, Doherty D, Hill SJ, Gerber AS, Huber GA.

PLoS One. 2019 Jan 7;14(1):e0209765. doi: 10.1371/journal.pone.0209765. eCollection 2019.


Structure-based exploration and pharmacological evaluation of N-substituted piperidin-4-yl-methanamine CXCR4 chemokine receptor antagonists.

Adlere I, Sun S, Zarca A, Roumen L, Gozelle M, Viciano CP, Caspar B, Arimont M, Bebelman JP, Briddon SJ, Hoffmann C, Hill SJ, Smit MJ, Vischer HF, Wijtmans M, de Graaf C, de Esch IJP, Leurs R.

Eur J Med Chem. 2019 Jan 15;162:631-649. doi: 10.1016/j.ejmech.2018.10.060. Epub 2018 Oct 30.


Fecal source tracking and eDNA profiling in an urban creek following an extreme rain event.

Staley ZR, Chuong JD, Hill SJ, Grabuski J, Shokralla S, Hajibabaei M, Edge TA.

Sci Rep. 2018 Sep 26;8(1):14390. doi: 10.1038/s41598-018-32680-z.


Circulating epinephrine is not required for chronic stress to enhance metastasis.

Walker AK, Martelli D, Ziegler AI, Lambert GW, Phillips SE, Hill SJ, McAllen RM, Sloan EK.

Psychoneuroendocrinology. 2019 Jan;99:191-195. doi: 10.1016/j.psyneuen.2018.09.012. Epub 2018 Sep 15.


Visualizing Ligand Binding to a GPCR In Vivo Using NanoBRET.

Alcobia DC, Ziegler AI, Kondrashov A, Comeo E, Mistry S, Kellam B, Chang A, Woolard J, Hill SJ, Sloan EK.

iScience. 2018 Aug 31;6:280-288. doi: 10.1016/j.isci.2018.08.006. Epub 2018 Aug 11.


Comparison of Micropore Distribution in Cell Walls of Softwood and Hardwood Xylem.

Donaldson LA, Cairns M, Hill SJ.

Plant Physiol. 2018 Nov;178(3):1142-1153. doi: 10.1104/pp.18.00883. Epub 2018 Sep 14.


Prediction of DNA Repair Inhibitor Response in Short-Term Patient-Derived Ovarian Cancer Organoids.

Hill SJ, Decker B, Roberts EA, Horowitz NS, Muto MG, Worley MJ Jr, Feltmate CM, Nucci MR, Swisher EM, Nguyen H, Yang C, Morizane R, Kochupurakkal BS, Do KT, Konstantinopoulos PA, Liu JF, Bonventre JV, Matulonis UA, Shapiro GI, Berkowitz RS, Crum CP, D'Andrea AD.

Cancer Discov. 2018 Nov;8(11):1404-1421. doi: 10.1158/2159-8290.CD-18-0474. Epub 2018 Sep 13.


A non-functional galanin receptor-2 in a multiple sclerosis patient.

Garcia-Rosa S, Trivella DB, Marques VD, Serafim RB, Pereira JG, Lorenzi JC, Molfetta GA, Christo PP, Olival GS, Marchitto VB, Brum DG, Sabedot TS, Noushmehr H, Farias AS, Santos LM, Nogueira-Machado JA, Souza JE, Romano CM, Conde RM, Santos AC, Guerreiro CT, Schreuder WH, Gleber-Netto FO, Amorim M, Valieris R, Silva ITD, Silva WA Jr, Nunes DN, Oliveira PS, Valente V, Arruda MA, Hill SJ, Barreira AA, Dias-Neto E.

Pharmacogenomics J. 2019 Feb;19(1):72-82. doi: 10.1038/s41397-018-0032-6. Epub 2018 Aug 22.


Real-Time Ligand Binding of Fluorescent VEGF-A Isoforms that Discriminate between VEGFR2 and NRP1 in Living Cells.

Peach CJ, Kilpatrick LE, Friedman-Ohana R, Zimmerman K, Robers MB, Wood KV, Woolard J, Hill SJ.

Cell Chem Biol. 2018 Oct 18;25(10):1208-1218.e5. doi: 10.1016/j.chembiol.2018.06.012. Epub 2018 Jul 26.


Consumer engagement critical to success in an Australian research project: reflections from those involved.

Synnot AJ, Cherry CL, Summers MP, Stuckey R, Milne CA, Lowe DB, Hill SJ.

Aust J Prim Health. 2018 Jul;24(3):197-203. doi: 10.1071/PY17107.


Research priorities in health communication and participation: international survey of consumers and other stakeholders.

Synnot A, Bragge P, Lowe D, Nunn JS, O'Sullivan M, Horvat L, Tong A, Kay D, Ghersi D, McDonald S, Poole N, Bourke N, Lannin N, Vadasz D, Oliver S, Carey K, Hill SJ.

BMJ Open. 2018 May 8;8(5):e019481. doi: 10.1136/bmjopen-2017-019481.


Molecular Pharmacology of VEGF-A Isoforms: Binding and Signalling at VEGFR2.

Peach CJ, Mignone VW, Arruda MA, Alcobia DC, Hill SJ, Kilpatrick LE, Woolard J.

Int J Mol Sci. 2018 Apr 23;19(4). pii: E1264. doi: 10.3390/ijms19041264. Review.


Correction to Synthesis and Evaluation of the First Fluorescent Antagonists of the Human P2Y2 Receptor Based on AR-C118925.

Conroy S, Kindon ND, Glenn J, Stoddart LA, Lewis RJ, Hill SJ, Kellam B, Stocks MJ.

J Med Chem. 2018 May 10;61(9):4272. doi: 10.1021/acs.jmedchem.8b00606. Epub 2018 Apr 24. No abstract available.


Thoracoscopic Repair of Congenital Diaphragmatic Hernia After Extracorporeal Membrane Oxygenation: Feasibility and Outcomes.

Schlager A, Arps K, Siddharthan R, Glenn I, Hill SJ, Wulkan ML, Keene SD, Clifton MS.

J Laparoendosc Adv Surg Tech A. 2018 Jun;28(6):774-779. doi: 10.1089/lap.2016.0583. Epub 2018 Mar 12.


Synthesis and Evaluation of the First Fluorescent Antagonists of the Human P2Y2 Receptor Based on AR-C118925.

Conroy S, Kindon ND, Glenn J, Stoddart LA, Lewis RJ, Hill SJ, Kellam B, Stocks MJ.

J Med Chem. 2018 Apr 12;61(7):3089-3113. doi: 10.1021/acs.jmedchem.8b00139. Epub 2018 Mar 28. Erratum in: J Med Chem. 2018 May 10;61(9):4272.


Development of novel fluorescent histamine H1-receptor antagonists to study ligand-binding kinetics in living cells.

Stoddart LA, Vernall AJ, Bouzo-Lorenzo M, Bosma R, Kooistra AJ, de Graaf C, Vischer HF, Leurs R, Briddon SJ, Kellam B, Hill SJ.

Sci Rep. 2018 Jan 25;8(1):1572. doi: 10.1038/s41598-018-19714-2.


A Non-imaging High Throughput Approach to Chemical Library Screening at the Unmodified Adenosine-A3 Receptor in Living Cells.

Arruda MA, Stoddart LA, Gherbi K, Briddon SJ, Kellam B, Hill SJ.

Front Pharmacol. 2017 Dec 13;8:908. doi: 10.3389/fphar.2017.00908. eCollection 2017.


Studying GPCR Pharmacology in Membrane Microdomains: Fluorescence Correlation Spectroscopy Comes of Age.

Briddon SJ, Kilpatrick LE, Hill SJ.

Trends Pharmacol Sci. 2018 Feb;39(2):158-174. doi: 10.1016/ Epub 2017 Dec 22. Review.


Fluorescence Approaches Unravel Spatial and Temporal Aspects of GPCR Organisation, Location, and Intracellular Signalling.

Hill SJ, Watson SP.

Trends Pharmacol Sci. 2018 Feb;39(2):91-92. doi: 10.1016/ Epub 2017 Dec 21. No abstract available.


NanoBRET Approaches to Study Ligand Binding to GPCRs and RTKs.

Stoddart LA, Kilpatrick LE, Hill SJ.

Trends Pharmacol Sci. 2018 Feb;39(2):136-147. doi: 10.1016/ Epub 2017 Nov 10. Review.


Plant Fibre: Molecular Structure and Biomechanical Properties, of a Complex Living Material, Influencing Its Deconstruction towards a Biobased Composite.

Sorieul M, Dickson A, Hill SJ, Pearson H.

Materials (Basel). 2016 Jul 26;9(8). pii: E618. doi: 10.3390/ma9080618. Review.


Congenital H-type tracheoesophageal fistula: A multicenter review of outcomes in a rare disease.

Fallon SC, Langer JC, St Peter SD, Tsao K, Kellagher CM, Lal DR, Whitehouse JS, Diesen DL, Rollins MD, Pontarelli E, Malek MM, Iqbal CW, Upperman JS, Leys CM, Wulkan ML, Hill SJ, Blakely ML, Kane TD, Wesson DE.

J Pediatr Surg. 2017 Nov;52(11):1711-1714. doi: 10.1016/j.jpedsurg.2017.05.002. Epub 2017 May 11.


Higher predation risk for insect prey at low latitudes and elevations.

Roslin T, Hardwick B, Novotny V, Petry WK, Andrew NR, Asmus A, Barrio IC, Basset Y, Boesing AL, Bonebrake TC, Cameron EK, Dáttilo W, Donoso DA, Drozd P, Gray CL, Hik DS, Hill SJ, Hopkins T, Huang S, Koane B, Laird-Hopkins B, Laukkanen L, Lewis OT, Milne S, Mwesige I, Nakamura A, Nell CS, Nichols E, Prokurat A, Sam K, Schmidt NM, Slade A, Slade V, Suchanková A, Teder T, van Nouhuys S, Vandvik V, Weissflog A, Zhukovich V, Slade EM.

Science. 2017 May 19;356(6339):742-744. doi: 10.1126/science.aaj1631.


Novel selective β1-adrenoceptor antagonists for concomitant cardiovascular and respiratory disease.

Baker JG, Gardiner SM, Woolard J, Fromont C, Jadhav GP, Mistry SN, Thompson KSJ, Kellam B, Hill SJ, Fischer PM.

FASEB J. 2017 Jul;31(7):3150-3166. doi: 10.1096/fj.201601305R. Epub 2017 Apr 11.


Real-time analysis of the binding of fluorescent VEGF165a to VEGFR2 in living cells: Effect of receptor tyrosine kinase inhibitors and fate of internalized agonist-receptor complexes.

Kilpatrick LE, Friedman-Ohana R, Alcobia DC, Riching K, Peach CJ, Wheal AJ, Briddon SJ, Robers MB, Zimmerman K, Machleidt T, Wood KV, Woolard J, Hill SJ.

Biochem Pharmacol. 2017 Jul 15;136:62-75. doi: 10.1016/j.bcp.2017.04.006. Epub 2017 Apr 7.


How could health information be improved? Recommended actions from the Victorian Consultation on Health Literacy.

Hill SJ, Sofra TA.

Aust Health Rev. 2018 Apr;42(2):134-139. doi: 10.1071/AH16106.


Design and Elaboration of a Tractable Tricyclic Scaffold To Synthesize Druglike Inhibitors of Dipeptidyl Peptidase-4 (DPP-4), Antagonists of the C-C Chemokine Receptor Type 5 (CCR5), and Highly Potent and Selective Phosphoinositol-3 Kinase δ (PI3Kδ) Inhibitors.

Schwehm C, Kellam B, Garces AE, Hill SJ, Kindon ND, Bradshaw TD, Li J, Macdonald SJ, Rowedder JE, Stoddart LA, Stocks MJ.

J Med Chem. 2017 Feb 23;60(4):1534-1554. doi: 10.1021/acs.jmedchem.6b01801. Epub 2017 Feb 10.


Two familial ALS proteins function in prevention/repair of transcription-associated DNA damage.

Hill SJ, Mordes DA, Cameron LA, Neuberg DS, Landini S, Eggan K, Livingston DM.

Proc Natl Acad Sci U S A. 2016 Nov 29;113(48):E7701-E7709. Epub 2016 Nov 14.


Structure-Activity Relationships of the Sustained Effects of Adenosine A2A Receptor Agonists Driven by Slow Dissociation Kinetics.

Hothersall JD, Guo D, Sarda S, Sheppard RJ, Chen H, Keur W, Waring MJ, IJzerman AP, Hill SJ, Dale IL, Rawlins PB.

Mol Pharmacol. 2017 Jan;91(1):25-38. Epub 2016 Nov 1.

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