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Items: 1 to 50 of 188

1.

A conditional Pax6 depletion study with no morphological effect on the adult mouse corneal epithelium.

Dorà NJ, Manuel M, Kleinjan DJ, Price DJ, Collinson JM, Hill RE, West JD.

BMC Res Notes. 2018 Oct 5;11(1):705. doi: 10.1186/s13104-018-3812-9.

2.

Computer simulation of neutral drift among limbal epithelial stem cells of mosaic mice.

West JD, Mort RL, Hill RE, Morley SD, Collinson JM.

Stem Cell Res. 2018 Jul;30:1-11. doi: 10.1016/j.scr.2018.05.003. Epub 2018 May 13.

3.

Examining the role of protein structural dynamics in drug resistance in Mycobacterium tuberculosis.

Shaw DJ, Hill RE, Simpson N, Husseini FS, Robb K, Greetham GM, Towrie M, Parker AW, Robinson D, Hirst JD, Hoskisson PA, Hunt NT.

Chem Sci. 2017 Dec 1;8(12):8384-8399. doi: 10.1039/c7sc03336b. Epub 2017 Oct 16.

4.

Fibroblast growth factors (FGFs) prime the limb specific Shh enhancer for chromatin changes that balance histone acetylation mediated by E26 transformation-specific (ETS) factors.

Peluso S, Douglas A, Hill A, De Angelis C, Moore BL, Grimes G, Petrovich G, Essafi A, Hill RE.

Elife. 2017 Sep 26;6. pii: e28590. doi: 10.7554/eLife.28590.

5.

The Conserved Sonic Hedgehog Limb Enhancer Consists of Discrete Functional Elements that Regulate Precise Spatial Expression.

Lettice LA, Devenney P, De Angelis C, Hill RE.

Cell Rep. 2017 Aug 8;20(6):1396-1408. doi: 10.1016/j.celrep.2017.07.037.

6.

A ten-year comparison of women authorship in U.S. dermatology literature, 1999 vs. 2009.

Zhang S, Kim HY, Hill RES, Veledar E, Chen SC.

Int J Womens Dermatol. 2017 Feb 16;3(1 Suppl):S58-S61. doi: 10.1016/j.ijwd.2017.02.012. eCollection 2017 Mar.

7.

Safe application of regionalization for trade in poultry and poultry products during highly pathogenic avian influenza outbreaks in the USA.

Swayne DE, Hill RE, Clifford J.

Avian Pathol. 2017 Apr;46(2):125-130. doi: 10.1080/03079457.2016.1257775. Epub 2016 Dec 23. Review.

PMID:
27817200
8.

Shh and ZRS enhancer colocalisation is specific to the zone of polarising activity.

Williamson I, Lettice LA, Hill RE, Bickmore WA.

Development. 2016 Aug 15;143(16):2994-3001. doi: 10.1242/dev.139188. Epub 2016 Jul 11.

9.

Abnormal corneal epithelial maintenance in mice heterozygous for the micropinna microphthalmia mutation Mp.

Douvaras P, Dorà NJ, Mort RL, Lodge EJ, Hill RE, West JD.

Exp Eye Res. 2016 Aug;149:26-39. doi: 10.1016/j.exer.2016.05.021. Epub 2016 May 26.

10.

Ribonuclease H2 mutations induce a cGAS/STING-dependent innate immune response.

Mackenzie KJ, Carroll P, Lettice L, Tarnauskaitė Ž, Reddy K, Dix F, Revuelta A, Abbondati E, Rigby RE, Rabe B, Kilanowski F, Grimes G, Fluteau A, Devenney PS, Hill RE, Reijns MA, Jackson AP.

EMBO J. 2016 Apr 15;35(8):831-44. doi: 10.15252/embj.201593339. Epub 2016 Feb 22.

11.

A ten-year comparison of women authorship in U.S. dermatology literature, 1999 vs. 2009.

Zhang S, Kim HY, Hill RES, Veledar E, Chen SC.

Int J Womens Dermatol. 2016 Jan 27;2(1):1-4. doi: 10.1016/j.ijwd.2015.10.003. eCollection 2016 Mar.

12.

Lineage tracing in the adult mouse corneal epithelium supports the limbal epithelial stem cell hypothesis with intermittent periods of stem cell quiescence.

Dorà NJ, Hill RE, Collinson JM, West JD.

Stem Cell Res. 2015 Nov;15(3):665-677. doi: 10.1016/j.scr.2015.10.016. Epub 2015 Oct 28.

13.

Hemizygous Le-Cre transgenic mice have severe eye abnormalities on some genetic backgrounds in the absence of LoxP sites.

Dorà NJ, Collinson JM, Hill RE, West JD.

PLoS One. 2014 Oct 1;9(10):e109193. doi: 10.1371/journal.pone.0109193. eCollection 2014.

14.

Mapping the Shh long-range regulatory domain.

Anderson E, Devenney PS, Hill RE, Lettice LA.

Development. 2014 Oct;141(20):3934-43. doi: 10.1242/dev.108480. Epub 2014 Sep 24.

15.

Functional role of PilA in iron acquisition in the cyanobacterium Synechocystis sp. PCC 6803.

Lamb JJ, Hill RE, Eaton-Rye JJ, Hohmann-Marriott MF.

PLoS One. 2014 Aug 26;9(8):e105761. doi: 10.1371/journal.pone.0105761. eCollection 2014.

16.

Peristeen (ⓒ) transanal irrigation system for paediatric faecal incontinence: a single centre experience.

Nasher O, Hill RE, Peeraully R, Wright A, Singh SJ.

Int J Pediatr. 2014;2014:954315. doi: 10.1155/2014/954315. Epub 2014 May 6.

17.

Long range regulation of the sonic hedgehog gene.

Anderson E, Hill RE.

Curr Opin Genet Dev. 2014 Aug;27:54-9. doi: 10.1016/j.gde.2014.03.011. Epub 2014 May 23. Review.

PMID:
24859115
18.

Development of five digits is controlled by a bipartite long-range cis-regulator.

Lettice LA, Williamson I, Devenney PS, Kilanowski F, Dorin J, Hill RE.

Development. 2014 Apr;141(8):1715-25. doi: 10.1242/dev.095430.

19.

Plasmid construction by SLIC or sequence and ligation-independent cloning.

Hill RE, Eaton-Rye JJ.

Methods Mol Biol. 2014;1116:25-36. doi: 10.1007/978-1-62703-764-8_2.

PMID:
24395354
20.

Studying biomacromolecules with two-dimensional infrared spectroscopy.

Hill RE, Hunt NT, Hirst JD.

Adv Protein Chem Struct Biol. 2013;93:1-36. doi: 10.1016/B978-0-12-416596-0.00001-4.

PMID:
24018321
21.

Increased corneal epithelial turnover contributes to abnormal homeostasis in the Pax6(+/-) mouse model of aniridia.

Douvaras P, Mort RL, Edwards D, Ramaesh K, Dhillon B, Morley SD, Hill RE, West JD.

PLoS One. 2013 Aug 13;8(8):e71117. doi: 10.1371/journal.pone.0071117. eCollection 2013.

22.

Translating research into licensed vaccines and validated and licensed diagnostic tests.

Hill RE Jr, Foley PL, Clough NE, Ludemann LR, Murtle DC.

Dev Biol (Basel). 2013;135:53-8. doi: 10.1159/000259402. Epub 2013 May 14.

PMID:
23689883
23.

Alterations to the remote control of Shh gene expression cause congenital abnormalities.

Hill RE, Lettice LA.

Philos Trans R Soc Lond B Biol Sci. 2013 May 6;368(1620):20120357. doi: 10.1098/rstb.2012.0357. Print 2013.

24.

Performance of the Los Alamos National Laboratory spallation-driven solid-deuterium ultra-cold neutron source.

Saunders A, Makela M, Bagdasarova Y, Back HO, Boissevain J, Broussard LJ, Bowles TJ, Carr R, Currie SA, Filippone B, García A, Geltenbort P, Hickerson KP, Hill RE, Hoagland J, Hoedl S, Holley AT, Hogan G, Ito TM, Lamoreaux S, Liu CY, Liu J, Mammei RR, Martin J, Melconian D, Mendenhall MP, Morris CL, Mortensen RN, Pattie RW Jr, Pitt M, Plaster B, Ramsey J, Rios R, Sallaska A, Seestrom SJ, Sharapov EI, Sjue S, Sondheim WE, Teasdale W, Young AR, VornDick B, Vogelaar RB, Wang Z, Xu Y.

Rev Sci Instrum. 2013 Jan;84(1):013304. doi: 10.1063/1.4770063.

PMID:
23387639
25.

Stem cells and corneal epithelial maintenance: insights from the mouse and other animal models.

Mort RL, Douvaras P, Morley SD, Dorà N, Hill RE, Collinson JM, West JD.

Results Probl Cell Differ. 2012;55:357-94. doi: 10.1007/978-3-642-30406-4_19. Review.

26.

Anterior-posterior differences in HoxD chromatin topology in limb development.

Williamson I, Eskeland R, Lettice LA, Hill AE, Boyle S, Grimes GR, Hill RE, Bickmore WA.

Development. 2012 Sep;139(17):3157-67. doi: 10.1242/dev.081174.

27.

Enzymatic removal of ribonucleotides from DNA is essential for mammalian genome integrity and development.

Reijns MA, Rabe B, Rigby RE, Mill P, Astell KR, Lettice LA, Boyle S, Leitch A, Keighren M, Kilanowski F, Devenney PS, Sexton D, Grimes G, Holt IJ, Hill RE, Taylor MS, Lawson KA, Dorin JR, Jackson AP.

Cell. 2012 May 25;149(5):1008-22. doi: 10.1016/j.cell.2012.04.011. Epub 2012 May 10.

28.

Human limb abnormalities caused by disruption of hedgehog signaling.

Anderson E, Peluso S, Lettice LA, Hill RE.

Trends Genet. 2012 Aug;28(8):364-73. doi: 10.1016/j.tig.2012.03.012. Epub 2012 Apr 24. Review.

PMID:
22534646
29.

Opposing functions of the ETS factor family define Shh spatial expression in limb buds and underlie polydactyly.

Lettice LA, Williamson I, Wiltshire JH, Peluso S, Devenney PS, Hill AE, Essafi A, Hagman J, Mort R, Grimes G, DeAngelis CL, Hill RE.

Dev Cell. 2012 Feb 14;22(2):459-67. doi: 10.1016/j.devcel.2011.12.010.

30.

Effects of aberrant Pax6 gene dosage on mouse corneal pathophysiology and corneal epithelial homeostasis.

Mort RL, Bentley AJ, Martin FL, Collinson JM, Douvaras P, Hill RE, Morley SD, Fullwood NJ, West JD.

PLoS One. 2011;6(12):e28895. doi: 10.1371/journal.pone.0028895. Epub 2011 Dec 29.

31.

Rare corneal clones in mice suggest an age-related decrease of stem cell activity and support the limbal epithelial stem cell hypothesis.

Douvaras P, Webb S, Whitaker DA, Dorà N, Hill RE, Dorin JR, West JD.

Stem Cell Res. 2012 Jan;8(1):109-19. doi: 10.1016/j.scr.2011.08.007. Epub 2011 Sep 5.

32.

Enhancer-adoption as a mechanism of human developmental disease.

Lettice LA, Daniels S, Sweeney E, Venkataraman S, Devenney PS, Gautier P, Morrison H, Fantes J, Hill RE, FitzPatrick DR.

Hum Mutat. 2011 Dec;32(12):1492-9. doi: 10.1002/humu.21615. Epub 2011 Oct 20.

PMID:
21948517
33.

Opportunities to minimise animal use in pharmaceutical regulatory general toxicology: a cross-company review.

Sparrow SS, Robinson S, Bolam S, Bruce C, Danks A, Everett D, Fulcher S, Hill RE, Palmer H, Scott EW, Chapman KL.

Regul Toxicol Pharmacol. 2011 Nov;61(2):222-9. doi: 10.1016/j.yrtph.2011.08.001. Epub 2011 Aug 10. Review.

PMID:
21855593
34.

Enhancers: from developmental genetics to the genetics of common human disease.

Williamson I, Hill RE, Bickmore WA.

Dev Cell. 2011 Jul 19;21(1):17-9. doi: 10.1016/j.devcel.2011.06.008.

35.

Impaired spleen formation perturbs morphogenesis of the gastric lobe of the pancreas.

Hörnblad A, Eriksson AU, Sock E, Hill RE, Ahlgren U.

PLoS One. 2011;6(6):e21753. doi: 10.1371/journal.pone.0021753. Epub 2011 Jun 30.

36.

Wt1 is required for cardiovascular progenitor cell formation through transcriptional control of Snail and E-cadherin.

Martínez-Estrada OM, Lettice LA, Essafi A, Guadix JA, Slight J, Velecela V, Hall E, Reichmann J, Devenney PS, Hohenstein P, Hosen N, Hill RE, Muñoz-Chapuli R, Hastie ND.

Nat Genet. 2010 Jan;42(1):89-93. doi: 10.1038/ng.494. Epub 2009 Dec 20.

37.

Left-right asymmetry in gut development: what happens next?

Burn SF, Hill RE.

Bioessays. 2009 Oct;31(10):1026-37. doi: 10.1002/bies.200900056. Review.

PMID:
19708022
38.

Biochemical and structural characterization of alanine racemase from Bacillus anthracis (Ames).

Couñago RM, Davlieva M, Strych U, Hill RE, Krause KL.

BMC Struct Biol. 2009 Aug 20;9:53. doi: 10.1186/1472-6807-9-53.

39.

Pitta Vac: a quick and easy technique for upper and lower limb vacuum therapy.

Hill RE, Malic C, Burge TS.

J Plast Reconstr Aesthet Surg. 2010 Feb;63(2):e223-4. doi: 10.1016/j.bjps.2009.06.015. Epub 2009 Jul 4. No abstract available.

PMID:
19577968
40.

Effects of elevated Pax6 expression and genetic background on mouse eye development.

Chanas SA, Collinson JM, Ramaesh T, Dorà N, Kleinjan DA, Hill RE, West JD.

Invest Ophthalmol Vis Sci. 2009 Sep;50(9):4045-59. doi: 10.1167/iovs.07-1630. Epub 2009 Apr 22.

41.

A variant in the sonic hedgehog regulatory sequence (ZRS) is associated with triphalangeal thumb and deregulates expression in the developing limb.

Furniss D, Lettice LA, Taylor IB, Critchley PS, Giele H, Hill RE, Wilkie AO.

Hum Mol Genet. 2008 Aug 15;17(16):2417-23. doi: 10.1093/hmg/ddn141. Epub 2008 May 7.

42.

The dynamics of spleen morphogenesis.

Burn SF, Boot MJ, de Angelis C, Doohan R, Arques CG, Torres M, Hill RE.

Dev Biol. 2008 Jun 15;318(2):303-11. doi: 10.1016/j.ydbio.2008.03.031. Epub 2008 Mar 28.

43.

Long-range control of gene expression. Preface.

Hill RE, van Heyningen V.

Adv Genet. 2008;61:xiii-xv. doi: 10.1016/S0065-2660(07)00014-4. No abstract available.

PMID:
18282500
44.

Point mutations in a distant sonic hedgehog cis-regulator generate a variable regulatory output responsible for preaxial polydactyly.

Lettice LA, Hill AE, Devenney PS, Hill RE.

Hum Mol Genet. 2008 Apr 1;17(7):978-85. Epub 2007 Dec 21.

PMID:
18156157
45.

International harmonisation of regulatory requirements.

Holmes M, Hill RE.

Rev Sci Tech. 2007 Aug;26(2):415-20. Review.

46.

A highly conserved Wnt-dependent TCF4 binding site within the proximal enhancer of the anti-myogenic Msx1 gene supports expression within Pax3-expressing limb bud muscle precursor cells.

Miller KA, Barrow J, Collinson JM, Davidson S, Lear M, Hill RE, Mackenzie A.

Dev Biol. 2007 Nov 15;311(2):665-78. Epub 2007 Jul 26.

47.
48.

Spleen versus pancreas: strict control of organ interrelationship revealed by analyses of Bapx1-/- mice.

Asayesh A, Sharpe J, Watson RP, Hecksher-Sørensen J, Hastie ND, Hill RE, Ahlgren U.

Genes Dev. 2006 Aug 15;20(16):2208-13.

49.

Regulatory considerations for marker vaccines and diagnostic tests in the U.S.

Foley PL, Hill RE Jr.

Biologicals. 2005 Dec;33(4):253-6. Epub 2005 Oct 28.

PMID:
16257538
50.

Preaxial polydactyly: a model for defective long-range regulation in congenital abnormalities.

Lettice LA, Hill RE.

Curr Opin Genet Dev. 2005 Jun;15(3):294-300. Review.

PMID:
15917205

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