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Discovery and Qualification of Serum Protein Biomarker Candidates for Cholangiocarcinoma Diagnosis.

Duangkumpha K, Stoll T, Phetcharaburanin J, Yongvanit P, Thanan R, Techasen A, Namwat N, Khuntikeo N, Chamadol N, Roytrakul S, Mulvenna J, Mohamed A, Shah AK, Hill MM, Loilome W.

J Proteome Res. 2019 Jul 16. doi: 10.1021/acs.jproteome.9b00242. [Epub ahead of print]


To BE or not to BE: non-invasive screening for Barrett's esophagus, dysplasia and adenocarcinoma.

Shah AK, Joshi V, Hartel G, Barbour AP, Hill MM.

Transl Gastroenterol Hepatol. 2019 May 15;4:31. doi: 10.21037/tgh.2019.04.08. eCollection 2019. No abstract available.


Overexpression of miRNA-25-3p inhibits Notch1 signaling and TGF-β-induced collagen expression in hepatic stellate cells.

Genz B, Coleman MA, Irvine KM, Kutasovic JR, Miranda M, Gratte FD, Tirnitz-Parker JEE, Olynyk JK, Calvopina DA, Weis A, Cloonan N, Robinson H, Hill MM, Al-Ejeh F, Ramm GA.

Sci Rep. 2019 Jun 12;9(1):8541. doi: 10.1038/s41598-019-44865-1.


High phthalate exposure increased urinary concentrations of quinolinic acid, implicated in the pathogenesis of neurological disorders: Is this a potential missing link?

Nassan FL, Gunn JA, Hill MM, Coull BA, Hauser R.

Environ Res. 2019 May;172:430-436. doi: 10.1016/j.envres.2019.02.034. Epub 2019 Feb 22.


Acute high intensity interval exercise reduces colon cancer cell growth.

Devin JL, Hill MM, Mourtzakis M, Quadrilatero J, Jenkins DG, Skinner TL.

J Physiol. 2019 Apr;597(8):2177-2184. doi: 10.1113/JP277648. Epub 2019 Mar 20.


Optimizing Size Exclusion Chromatography for Extracellular Vesicle Enrichment and Proteomic Analysis from Clinically Relevant Samples.

Lane RE, Korbie D, Trau M, Hill MM.

Proteomics. 2019 Apr;19(8):e1800156. doi: 10.1002/pmic.201800156. Epub 2019 Jan 25.


Advances and challenges in understanding the role of the lipid raft proteome in human health.

Mohamed A, Robinson H, Erramouspe PJ, Hill MM.

Expert Rev Proteomics. 2018 Dec;15(12):1053-1063. doi: 10.1080/14789450.2018.1544895. Epub 2018 Nov 13. Review.


RaftProt V2: understanding membrane microdomain function through lipid raft proteomes.

Mohamed A, Shah AD, Chen D, Hill MM.

Nucleic Acids Res. 2019 Jan 8;47(D1):D459-D463. doi: 10.1093/nar/gky948.


Iron Inhibits the Secretion of Apolipoprotein E in Cultured Human Adipocytes.

Britton LJ, Bridle K, Jaskowski LA, He J, Ng C, Ruelcke JE, Mohamed A, Reiling J, Santrampurwala N, Hill MM, Whitehead JP, Subramaniam VN, Crawford DHG.

Cell Mol Gastroenterol Hepatol. 2018 Apr 16;6(2):215-217.e8. doi: 10.1016/j.jcmgh.2018.04.005. eCollection 2018. No abstract available.


Intestinal Metaproteomics Reveals Host-Microbiota Interactions in Subjects at Risk for Type 1 Diabetes.

Gavin PG, Mullaney JA, Loo D, Cao KL, Gottlieb PA, Hill MM, Zipris D, Hamilton-Williams EE.

Diabetes Care. 2018 Oct;41(10):2178-2186. doi: 10.2337/dc18-0777. Epub 2018 Aug 12.


Evaluation of Serum Glycoprotein Biomarker Candidates for Detection of Esophageal Adenocarcinoma and Surveillance of Barrett's Esophagus.

Shah AK, Hartel G, Brown I, Winterford C, Na R, Cao KL, Spicer BA, Dunstone MA, Phillips WA, Lord RV, Barbour AP, Watson DI, Joshi V, Whiteman DC, Hill MM.

Mol Cell Proteomics. 2018 Dec;17(12):2324-2334. doi: 10.1074/mcp.RA118.000734. Epub 2018 Aug 10.


Extracellular vesicles as circulating cancer biomarkers: opportunities and challenges.

Lane RE, Korbie D, Hill MM, Trau M.

Clin Transl Med. 2018 May 31;7(1):14. doi: 10.1186/s40169-018-0192-7. Review.


Onset patterns in autism: Variation across informants, methods, and timing.

Ozonoff S, Gangi D, Hanzel EP, Hill A, Hill MM, Miller M, Schwichtenberg AJ, Steinfeld MB, Parikh C, Iosif AM.

Autism Res. 2018 May;11(5):788-797. doi: 10.1002/aur.1943. Epub 2018 Mar 10.


Serum profile changes in postpartum women with a history of childhood maltreatment: a combined metabolite and lipid fingerprinting study.

Koenig AM, Karabatsiakis A, Stoll T, Wilker S, Hennessy T, Hill MM, Kolassa IT.

Sci Rep. 2018 Feb 22;8(1):3468. doi: 10.1038/s41598-018-21763-6.


Author Correction: Tyrosine dephosphorylated cortactin downregulates contractility at the epithelial zonula adherens through SRGAP1.

Liang X, Budnar S, Gupta S, Verma S, Han SP, Hill MM, Daly RJ, Parton RG, Hamilton NA, Gomez GA, Yap AS.

Nat Commun. 2017 Dec 5;8(1):2021. doi: 10.1038/s41467-017-02131-w.


Tyrosine dephosphorylated cortactin downregulates contractility at the epithelial zonula adherens through SRGAP1.

Liang X, Budnar S, Gupta S, Verma S, Han SP, Hill MM, Daly RJ, Parton RG, Hamilton NA, Gomez GA, Yap AS.

Nat Commun. 2017 Oct 5;8(1):790. doi: 10.1038/s41467-017-00797-w. Erratum in: Nat Commun. 2017 Dec 5;8(1):2021.


Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer.

Soekmadji C, Riches JD, Russell PJ, Ruelcke JE, McPherson S, Wang C, Hovens CM, Corcoran NM; Australian Prostate Cancer Collaboration BioResource, Hill MM, Nelson CC.

Oncotarget. 2016 Aug 8;8(32):52237-52255. doi: 10.18632/oncotarget.11111. eCollection 2017 Aug 8.


Purification Protocols for Extracellular Vesicles.

Lane RE, Korbie D, Trau M, Hill MM.

Methods Mol Biol. 2017;1660:111-130. doi: 10.1007/978-1-4939-7253-1_10.


G9a drives hypoxia-mediated gene repression for breast cancer cell survival and tumorigenesis.

Casciello F, Al-Ejeh F, Kelly G, Brennan DJ, Ngiow SF, Young A, Stoll T, Windloch K, Hill MM, Smyth MJ, Gannon F, Lee JS.

Proc Natl Acad Sci U S A. 2017 Jul 3;114(27):7077-7082. doi: 10.1073/pnas.1618706114. Epub 2017 Jun 19.


Mass spectrometry analysis for amyloidosis typing - is the future bright for its clinical implementation?

Hill MM, Mollee PN.

Expert Rev Proteomics. 2017 Jul;14(7):565-566. doi: 10.1080/14789450.2017.1322905. Epub 2017 May 3. No abstract available.


Statistical Evaluation of Labeled Comparative Profiling Proteomics Experiments Using Permutation Test.

Nguyen HD, McLachlan GJ, Hill MM.

Methods Mol Biol. 2017;1549:109-117.


Implementation and evaluation of amyloidosis subtyping by laser-capture microdissection and tandem mass spectrometry.

Mollee P, Boros S, Loo D, Ruelcke JE, Lakis VA, Cao KL, Renaut P, Hill MM.

Clin Proteomics. 2016 Oct 27;13:30. eCollection 2016.


Reducing the cost of semi-automated in-gel tryptic digestion and GeLC sample preparation for high-throughput proteomics.

Ruelcke JE, Loo D, Hill MM.

J Proteomics. 2016 Oct 21;149:3-6. doi: 10.1016/j.jprot.2016.03.025. Epub 2016 Apr 13.


Early Detection of ADHD: Insights From Infant Siblings of Children With Autism.

Miller M, Iosif AM, Young GS, Hill MM, Ozonoff S.

J Clin Child Adolesc Psychol. 2018 Sep-Oct;47(5):737-744. doi: 10.1080/15374416.2016.1220314. Epub 2016 Oct 12.


Glyco-centric lectin magnetic bead array (LeMBA) - proteomics dataset of human serum samples from healthy, Barrett׳s esophagus and esophageal adenocarcinoma individuals.

Shah AK, Lê Cao KA, Choi E, Chen D, Gautier B, Nancarrow D, Whiteman DC, Baker PR, Clauser KR, Chalkley RJ, Saunders NA, Barbour AP, Joshi V, Hill MM.

Data Brief. 2016 Apr 1;7:1058-62. doi: 10.1016/j.dib.2016.03.081. eCollection 2016 Jun.


Integrative Analysis of Subcellular Quantitative Proteomics Studies Reveals Functional Cytoskeleton Membrane-Lipid Raft Interactions in Cancer.

Shah AD, Inder KL, Shah AK, Cristino AS, McKie AB, Gabra H, Davis MJ, Hill MM.

J Proteome Res. 2016 Oct 7;15(10):3451-3462. Epub 2016 Sep 2.


Coronin 1B Reorganizes the Architecture of F-Actin Networks for Contractility at Steady-State and Apoptotic Adherens Junctions.

Michael M, Meiring JCM, Acharya BR, Matthews DR, Verma S, Han SP, Hill MM, Parton RG, Gomez GA, Yap AS.

Dev Cell. 2016 Apr 4;37(1):58-71. doi: 10.1016/j.devcel.2016.03.008.


Electrochemical detection of protein glycosylation using lectin and protein-gold affinity interactions.

Yadav S, Carrascosa LG, Sina AA, Shiddiky MJ, Hill MM, Trau M.

Analyst. 2016 Apr 21;141(8):2356-61. doi: 10.1039/c6an00528d. Epub 2016 Mar 16.


Enrichment and identification of glycoproteins in human saliva using lectin magnetic bead arrays.

Caragata M, Shah AK, Schulz BL, Hill MM, Punyadeera C.

Anal Biochem. 2016 Mar 15;497:76-82. doi: 10.1016/j.ab.2015.11.024. Epub 2015 Dec 30.


Adipocytes promote prostate cancer stem cell self-renewal through amplification of the cholecystokinin autocrine loop.

Tang KD, Liu J, Jovanovic L, An J, Hill MM, Vela I, Lee TK, Ma S, Nelson C, Russell PJ, Clements JA, Ling MT.

Oncotarget. 2016 Jan 26;7(4):4939-48. doi: 10.18632/oncotarget.6643.


Serum Glycoprotein Biomarker Discovery and Qualification Pipeline Reveals Novel Diagnostic Biomarker Candidates for Esophageal Adenocarcinoma.

Shah AK, Cao KA, Choi E, Chen D, Gautier B, Nancarrow D, Whiteman DC, Saunders NA, Barbour AP, Joshi V, Hill MM.

Mol Cell Proteomics. 2015 Nov;14(11):3023-39. doi: 10.1074/mcp.M115.050922. Epub 2015 Sep 24.


SseK3 Is a Salmonella Effector That Binds TRIM32 and Modulates the Host's NF-κB Signalling Activity.

Yang Z, Soderholm A, Lung TW, Giogha C, Hill MM, Brown NF, Hartland E, Teasdale RD.

PLoS One. 2015 Sep 22;10(9):e0138529. doi: 10.1371/journal.pone.0138529. eCollection 2015.


Non-caveolar caveolin-1 expression in prostate cancer cells promotes lymphangiogenesis.

Nassar ZD, Hill MM, Parton RG, Francois M, Parat MO.

Oncoscience. 2015 Aug 3;2(7):635-45. eCollection 2015.


Molecular Characterization of Caveolin-induced Membrane Curvature.

Ariotti N, Rae J, Leneva N, Ferguson C, Loo D, Okano S, Hill MM, Walser P, Collins BM, Parton RG.

J Biol Chem. 2015 Oct 9;290(41):24875-90. doi: 10.1074/jbc.M115.644336. Epub 2015 Aug 24.


JIP4 is a PLK1 binding protein that regulates p38MAPK activity in G2 phase.

Pinder A, Loo D, Harrington B, Oakes V, Hill MM, Gabrielli B.

Cell Signal. 2015 Nov;27(11):2296-303. doi: 10.1016/j.cellsig.2015.08.009. Epub 2015 Aug 17.


Critical role of CAV1/caveolin-1 in cell stress responses in human breast cancer cells via modulation of lysosomal function and autophagy.

Shi Y, Tan SH, Ng S, Zhou J, Yang ND, Koo GB, McMahon KA, Parton RG, Hill MM, Del Pozo MA, Kim YS, Shen HM.

Autophagy. 2015;11(5):769-84. doi: 10.1080/15548627.2015.1034411.


Diet-induced hypercholesterolemia promotes androgen-independent prostate cancer metastasis via IQGAP1 and caveolin-1.

Moon H, Ruelcke JE, Choi E, Sharpe LJ, Nassar ZD, Bielefeldt-Ohmann H, Parat MO, Shah A, Francois M, Inder KL, Brown AJ, Russell PJ, Parton RG, Hill MM.

Oncotarget. 2015 Apr 10;6(10):7438-53.


Senescent human hepatocytes express a unique secretory phenotype and promote macrophage migration.

Irvine KM, Skoien R, Bokil NJ, Melino M, Thomas GP, Loo D, Gabrielli B, Hill MM, Sweet MJ, Clouston AD, Powell EE.

World J Gastroenterol. 2014 Dec 21;20(47):17851-62. doi: 10.3748/wjg.v20.i47.17851.


RaftProt: mammalian lipid raft proteome database.

Shah A, Chen D, Boda AR, Foster LJ, Davis MJ, Hill MM.

Nucleic Acids Res. 2015 Jan;43(Database issue):D335-8. doi: 10.1093/nar/gku1131. Epub 2014 Nov 11.


EVpedia: a community web portal for extracellular vesicles research.

Kim DK, Lee J, Kim SR, Choi DS, Yoon YJ, Kim JH, Go G, Nhung D, Hong K, Jang SC, Kim SH, Park KS, Kim OY, Park HT, Seo JH, Aikawa E, Baj-Krzyworzeka M, van Balkom BW, Belting M, Blanc L, Bond V, Bongiovanni A, Borràs FE, Buée L, Buzás EI, Cheng L, Clayton A, Cocucci E, Dela Cruz CS, Desiderio DM, Di Vizio D, Ekström K, Falcon-Perez JM, Gardiner C, Giebel B, Greening DW, Gross JC, Gupta D, Hendrix A, Hill AF, Hill MM, Nolte-'t Hoen E, Hwang DW, Inal J, Jagannadham MV, Jayachandran M, Jee YK, Jørgensen M, Kim KP, Kim YK, Kislinger T, Lässer C, Lee DS, Lee H, van Leeuwen J, Lener T, Liu ML, Lötvall J, Marcilla A, Mathivanan S, Möller A, Morhayim J, Mullier F, Nazarenko I, Nieuwland R, Nunes DN, Pang K, Park J, Patel T, Pocsfalvi G, Del Portillo H, Putz U, Ramirez MI, Rodrigues ML, Roh TY, Royo F, Sahoo S, Schiffelers R, Sharma S, Siljander P, Simpson RJ, Soekmadji C, Stahl P, Stensballe A, Stępień E, Tahara H, Trummer A, Valadi H, Vella LJ, Wai SN, Witwer K, Yáñez-Mó M, Youn H, Zeidler R, Gho YS.

Bioinformatics. 2015 Mar 15;31(6):933-9. doi: 10.1093/bioinformatics/btu741. Epub 2014 Nov 10.


Electrochemical detection of glycan and protein epitopes of glycoproteins in serum.

Shah AK, Hill MM, Shiddiky MJ, Trau M.

Analyst. 2014 Nov 21;139(22):5970-6. doi: 10.1039/c4an00781f.


Total transcriptome, proteome, and allergome of Johnson grass pollen, which is important for allergic rhinitis in subtropical regions.

Campbell BC, Gilding EK, Timbrell V, Guru P, Loo D, Zennaro D, Mari A, Solley G, Hill MM, Godwin ID, Davies JM.

J Allergy Clin Immunol. 2015 Jan;135(1):133-42. doi: 10.1016/j.jaci.2014.06.034. Epub 2014 Aug 13.


Online quantitative proteomics p-value calculator for permutation-based statistical testing of peptide ratios.

Chen D, Shah A, Nguyen H, Loo D, Inder KL, Hill MM.

J Proteome Res. 2014 Sep 5;13(9):4184-91. doi: 10.1021/pr500525e. Epub 2014 Jul 30.


Cavin-1/PTRF alters prostate cancer cell-derived extracellular vesicle content and internalization to attenuate extracellular vesicle-mediated osteoclastogenesis and osteoblast proliferation.

Inder KL, Ruelcke JE, Petelin L, Moon H, Choi E, Rae J, Blumenthal A, Hutmacher D, Saunders NA, Stow JL, Parton RG, Hill MM.

J Extracell Vesicles. 2014 Jun 25;3. doi: 10.3402/jev.v3.23784. eCollection 2014.


Endocytic crosstalk: cavins, caveolins, and caveolae regulate clathrin-independent endocytosis.

Chaudhary N, Gomez GA, Howes MT, Lo HP, McMahon KA, Rae JA, Schieber NL, Hill MM, Gaus K, Yap AS, Parton RG.

PLoS Biol. 2014 Apr 8;12(4):e1001832. doi: 10.1371/journal.pbio.1001832. eCollection 2014 Apr.


Caveolae regulate the nanoscale organization of the plasma membrane to remotely control Ras signaling.

Ariotti N, Fernández-Rojo MA, Zhou Y, Hill MM, Rodkey TL, Inder KL, Tanner LB, Wenk MR, Hancock JF, Parton RG.

J Cell Biol. 2014 Mar 3;204(5):777-92. doi: 10.1083/jcb.201307055. Epub 2014 Feb 24.


Statins: protectors or pretenders in prostate cancer?

Moon H, Hill MM, Roberts MJ, Gardiner RA, Brown AJ.

Trends Endocrinol Metab. 2014 Apr;25(4):188-96. doi: 10.1016/j.tem.2013.12.007. Epub 2014 Jan 22. Review.


PTRF/Cavin-1 decreases prostate cancer angiogenesis and lymphangiogenesis.

Nassar ZD, Moon H, Duong T, Neo L, Hill MM, Francois M, Parton RG, Parat MO.

Oncotarget. 2013 Oct;4(10):1844-55.


Caveola-forming proteins caveolin-1 and PTRF in prostate cancer.

Nassar ZD, Hill MM, Parton RG, Parat MO.

Nat Rev Urol. 2013 Sep;10(9):529-36. doi: 10.1038/nrurol.2013.168. Epub 2013 Aug 13. Review.


PTRF/cavin-1 neutralizes non-caveolar caveolin-1 microdomains in prostate cancer.

Moon H, Lee CS, Inder KL, Sharma S, Choi E, Black DM, Lê Cao KA, Winterford C, Coward JI, Ling MT; Australian Prostate Cancer BioResource, Craik DJ, Parton RG, Russell PJ, Hill MM.

Oncogene. 2014 Jul 3;33(27):3561-70. doi: 10.1038/onc.2013.315. Epub 2013 Aug 12.


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