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Association of Clinical, Imaging, and Thrombus Characteristics With Recanalization of Visible Intracranial Occlusion in Patients With Acute Ischemic Stroke.

Menon BK, Al-Ajlan FS, Najm M, Puig J, Castellanos M, Dowlatshahi D, Calleja A, Sohn SI, Ahn SH, Poppe A, Mikulik R, Asdaghi N, Field TS, Jin A, Asil T, Boulanger JM, Smith EE, Coutts SB, Barber PA, Bal S, Subramanian S, Mishra S, Trivedi A, Dey S, Eesa M, Sajobi T, Goyal M, Hill MD, Demchuk AM; INTERRSeCT Study Investigators.

JAMA. 2018 Sep 11;320(10):1017-1026. doi: 10.1001/jama.2018.12498.


eTICI reperfusion: defining success in endovascular stroke therapy.

Liebeskind DS, Bracard S, Guillemin F, Jahan R, Jovin TG, Majoie CB, Mitchell PJ, van der Lugt A, Menon BK, San Román L, Campbell BC, Muir KW, Hill MD, Dippel DW, Saver JL, Demchuk AM, Dávalos A, White P, Brown S, Goyal M; HERMES Collaborators.

J Neurointerv Surg. 2018 Sep 7. pii: neurintsurg-2018-014127. doi: 10.1136/neurintsurg-2018-014127. [Epub ahead of print]


Modeling Stroke Patient Transport for All Patients With Suspected Large-Vessel Occlusion.

Holodinsky JK, Williamson TS, Demchuk AM, Zhao H, Zhu L, Francis MJ, Goyal M, Hill MD, Kamal N.

JAMA Neurol. 2018 Sep 4. doi: 10.1001/jamaneurol.2018.2424. [Epub ahead of print]


Diffusion-weighted imaging lesion growth occurs despite recanalization in acute ischemic stroke: Implications for future treatment trials.

Sah RG, d'Esterre CD, Hill MD, Hafeez M, Tariq S, Forkert ND, Frayne R, Demchuk AM, Goyal M, Barber PA.

Int J Stroke. 2018 Sep 4:1747493018798550. doi: 10.1177/1747493018798550. [Epub ahead of print]


Long-term neurological, vascular, and mortality outcomes after stroke.

Singh RJ, Chen S, Ganesh A, Hill MD.

Int J Stroke. 2018 Aug 30:1747493018798526. doi: 10.1177/1747493018798526. [Epub ahead of print]


Canadian Stroke Best Practice Consensus Statement: Acute Stroke Management during pregnancy.

Ladhani NNN, Swartz RH, Foley N, Nerenberg K, Smith EE, Gubitz G, Dowlatshahi D, Potts J, Ray JG, Barrett J, Bushnell C, Bal S, Chan WS, Chari R, El Amrani M, Gandhi S, Hill MD, James A, Jeerakathil T, Jin A, Kirton A, Lanthier S, Lausman A, Leffert LR, Mandzia J, Menon B, Pikula A, Poppe A, Saposnik G, Sharma M, Bhogal S, Smitko E, Lindsay MP; Heart and Stroke Foundation Canadian Stroke Best Practice and Quality Advisory Committees; Canadian Stroke Consortium.

Int J Stroke. 2018 Jan 1:1747493018786617. doi: 10.1177/1747493018786617. [Epub ahead of print]


Tenecteplase Knocking on the Door: The EXTEND-IA TNK Trial.

Hill MD, Michel P.

Stroke. 2018 Jul 17. pii: STROKEAHA.118.022318. doi: 10.1161/STROKEAHA.118.022318. [Epub ahead of print] Review. No abstract available.


Improving care for acute in-hospital ischemic strokes-A narrative review.

Chen S, Singh RJ, Kamal N, Hill MD.

Int J Stroke. 2018 Jan 1:1747493018790029. doi: 10.1177/1747493018790029. [Epub ahead of print]


Acute Ischemic Stroke Biology Demands Fast Treatment.

Al Sultan AS, Hill MD.

Circulation. 2018 Jul 17;138(3):241-243. doi: 10.1161/CIRCULATIONAHA.118.034653. No abstract available.


Determining optimal poststroke exercise: Study protocol for a randomized controlled trial investigating therapeutic intensity and dose on functional recovery during stroke inpatient rehabilitation.

Klassen TD, Dukelow SP, Bayley MT, Benavente O, Hill MD, Krassioukov A, Liu-Ambrose T, Pooyania S, Poulin MJ, Yao J, Eng JJ.

Int J Stroke. 2018 Jan 1:1747493018785064. doi: 10.1177/1747493018785064. [Epub ahead of print]


Protective Effects of Exercise on Cognition and Brain Health in Older Adults.

Tyndall AV, Clark CM, Anderson TJ, Hogan DB, Hill MD, Longman RS, Poulin MJ.

Exerc Sport Sci Rev. 2018 Oct;46(4):215-223. doi: 10.1249/JES.0000000000000161.


Rationale and design for the detection and neurological impact of cerebrovascular events in non-cardiac surgery patients cohort evaluation (NeuroVISION) study: a prospective international cohort study.

Mrkobrada M, Chan MTV, Cowan D, Spence J, Campbell D, Wang CY, Torres D, Malaga G, Sanders RD, Brown C, Sigamani A, Szczeklik W, Dmytriw AA, Agid R, Smith EE, Hill MD, Sharma M, Sharma M, Tsai S, Mensinkai A, Sahlas DJ, Guyatt G, Pettit S, Copland I, Wu WKK, Yu SCH, Gin T, Loh PS, Ramli N, Siow YL, Short TG, Waymouth E, Kumar J, Dasgupta M, Murkin JM, Fuentes M, Ortiz-Soriano V, Lindroth H, Simpson S, Sessler D, Devereaux PJ.

BMJ Open. 2018 Jul 6;8(7):e021521. doi: 10.1136/bmjopen-2018-021521.


Bridging the Evidence-to-Practice Gap in Stroke Care.

Hill MD, Kamal N, Jeerakathil T.

JAMA. 2018 Jul 17;320(3):236-237. doi: 10.1001/jama.2018.8803. No abstract available.


Suggested modification of presentation of stroke trial results.

Goyal M, Ganesh A, Brown S, Menon BK, Hill MD.

Int J Stroke. 2018 Jan 1:1747493018778122. doi: 10.1177/1747493018778122. [Epub ahead of print]


Hypertension Canada's 2018 Guidelines for Diagnosis, Risk Assessment, Prevention, and Treatment of Hypertension in Adults and Children.

Nerenberg KA, Zarnke KB, Leung AA, Dasgupta K, Butalia S, McBrien K, Harris KC, Nakhla M, Cloutier L, Gelfer M, Lamarre-Cliche M, Milot A, Bolli P, Tremblay G, McLean D, Padwal RS, Tran KC, Grover S, Rabkin SW, Moe GW, Howlett JG, Lindsay P, Hill MD, Sharma M, Field T, Wein TH, Shoamanesh A, Dresser GK, Hamet P, Herman RJ, Burgess E, Gryn SE, Grégoire JC, Lewanczuk R, Poirier L, Campbell TS, Feldman RD, Lavoie KL, Tsuyuki RT, Honos G, Prebtani APH, Kline G, Schiffrin EL, Don-Wauchope A, Tobe SW, Gilbert RE, Leiter LA, Jones C, Woo V, Hegele RA, Selby P, Pipe A, McFarlane PA, Oh P, Gupta M, Bacon SL, Kaczorowski J, Trudeau L, Campbell NRC, Hiremath S, Roerecke M, Arcand J, Ruzicka M, Prasad GVR, Vallée M, Edwards C, Sivapalan P, Penner SB, Fournier A, Benoit G, Feber J, Dionne J, Magee LA, Logan AG, Côté AM, Rey E, Firoz T, Kuyper LM, Gabor JY, Townsend RR, Rabi DM, Daskalopoulou SS; Hypertension Canada.

Can J Cardiol. 2018 May;34(5):506-525. doi: 10.1016/j.cjca.2018.02.022. Epub 2018 Mar 1.


Direct mechanical thrombectomy in tPA-ineligible and -eligible patients versus the bridging approach: a meta-analysis.

Kaesmacher J, Mordasini P, Arnold M, López-Cancio E, Cerdá N, Boeckh-Behrens T, Kleine JF, Goyal M, Hill MD, Pereira VM, Saver JL, Gralla J, Fischer U.

J Neurointerv Surg. 2018 Apr 28. pii: neurintsurg-2018-013834. doi: 10.1136/neurintsurg-2018-013834. [Epub ahead of print]


Is varicella vaccination associated with pediatric arterial ischemic stroke? A population-based cohort study.

MacDonald SE, Dover DC, Hill MD, Kirton A, Simmonds KA, Svenson LW.

Vaccine. 2018 May 11;36(20):2764-2767. doi: 10.1016/j.vaccine.2018.04.012. Epub 2018 Apr 11.


HeadPoST: Rightly positioned, or flat out wrong?

Alexandrov AW, Tsivgoulis G, Hill MD, Liebeskind DS, Schellinger P, Ovbiagele B, Arthur AS, Caso V, Nogueira RG, Hemphill JC 3rd, Grotta JC, Hacke W, Alexandrov AV.

Neurology. 2018 May 8;90(19):885-889. doi: 10.1212/WNL.0000000000005481. Epub 2018 Apr 11. Review.


Association of follow-up infarct volume with functional outcome in acute ischemic stroke: a pooled analysis of seven randomized trials.

Boers AMM, Jansen IGH, Beenen LFM, Devlin TG, San Roman L, Heo JH, Ribó M, Brown S, Almekhlafi MA, Liebeskind DS, Teitelbaum J, Lingsma HF, van Zwam WH, Cuadras P, du Mesnil de Rochemont R, Beaumont M, Brown MM, Yoo AJ, van Oostenbrugge RJ, Menon BK, Donnan GA, Mas JL, Roos YBWEM, Oppenheim C, van der Lugt A, Dowling RJ, Hill MD, Davalos A, Moulin T, Agrinier N, Demchuk AM, Lopes DK, Aja Rodríguez L, Dippel DWJ, Campbell BCV, Mitchell PJ, Al-Ajlan FS, Jovin TG, Madigan J, Albers GW, Soize S, Guillemin F, Reddy VK, Bracard S, Blasco J, Muir KW, Nogueira RG, White PM, Goyal M, Davis SM, Marquering HA, Majoie CBLM.

J Neurointerv Surg. 2018 Apr 7. pii: neurintsurg-2017-013724. doi: 10.1136/neurintsurg-2017-013724. [Epub ahead of print]


How to Review a Clinical Research Paper.

Hill MD.

Stroke. 2018 May;49(5):e204-e206. doi: 10.1161/STROKEAHA.118.021286. Epub 2018 Apr 5. Review. No abstract available.


Treat fast but abandon time from ischemic stroke onset as a criterion for treatment: The DAWN and DEFUSE-3 trials.

Hill MD, Goyal M.

Int J Stroke. 2018 Jun;13(4):344-347. doi: 10.1177/1747493018769004. Epub 2018 Apr 5. No abstract available.


Primary to comprehensive stroke center transfers: Appropriateness, not futility.

Goyal M, Menon BK, Wilson AT, Almekhlafi MA, McTaggart R, Jayaraman M, Demchuk AM, Hill MD.

Int J Stroke. 2018 Aug;13(6):550-553. doi: 10.1177/1747493018764072. Epub 2018 Mar 6.


Thrombolytic therapies for ischemic stroke: Triumphs and future challenges.

Moussaddy A, Demchuk AM, Hill MD.

Neuropharmacology. 2018 May 15;134(Pt B):272-279. doi: 10.1016/j.neuropharm.2017.11.010. Epub 2018 Mar 3. Review.


Secondary stroke prevention services in Canada: a cross-sectional survey and geospatial analysis of resources, capacity and geographic access.

Jewett L, Harroud A, Hill MD, Côté R, Wein T, Smith EE, Gubitz G, Demchuk AM, Sahlas DJ, Gladstone DJ, Lindsay MP.

CMAJ Open. 2018 Feb 21;6(1):E95-E102. doi: 10.9778/cmajo.20170130.


Telehealth for Remote Stroke Management.

Zerna C, Jeerakathil T, Hill MD.

Can J Cardiol. 2018 Jul;34(7):889-896. doi: 10.1016/j.cjca.2017.12.025. Epub 2017 Dec 27. Review.


Defining CT Perfusion Thresholds for Infarction in the Golden Hour and With Ultra-Early Reperfusion.

Najm M, Al-Ajlan FS, Boesen ME, Hur L, Kim CK, Fainardi E, Hill MD, Demchuk AM, Goyal M, Lee TY, Menon BK.

Can J Neurol Sci. 2018 May;45(3):339-342. doi: 10.1017/cjn.2017.287. Epub 2018 Feb 19.


The Optimal Anti-Coagulation for Enhanced-Risk Patients Post-Catheter Ablation for Atrial Fibrillation (OCEAN) trial.

Verma A, Ha ACT, Kirchhof P, Hindricks G, Healey JS, Hill MD, Sharma M, Wyse DG, Champagne J, Essebag V, Wells G, Gupta D, Heidbuchel H, Sanders P, Birnie DH.

Am Heart J. 2018 Mar;197:124-132. doi: 10.1016/j.ahj.2017.12.007. Epub 2017 Dec 8.


Pulmonary Embolism in Ischemic Stroke.

Eswaradass PV, Dey S, Singh D, Hill MD.

Can J Neurol Sci. 2018 May;45(3):343-345. doi: 10.1017/cjn.2017.288. Epub 2018 Jan 28.


A comparison of meta-analytic methods for synthesizing evidence from explanatory and pragmatic trials.

Sajobi TT, Li G, Awosoga O, Wang M, Menon BK, Hill MD, Thabane L.

Syst Rev. 2018 Jan 25;7(1):19. doi: 10.1186/s13643-017-0668-3.


Lack of Early Improvement Predicts Poor Outcome Following Acute Intracerebral Hemorrhage.

Yogendrakumar V, Smith EE, Demchuk AM, Aviv RI, Rodriguez-Luna D, Molina CA, Silva Blas Y, Dzialowski I, Kobayashi A, Boulanger JM, Lum C, Gubitz G, Padma V, Roy J, Kase CS, Bhatia R, Ali M, Lyden P, Hill MD, Dowlatshahi D; Prediction of haematoma growth and outcome in patients with intracerebral haemorrhage using the CT-angiography spot sign [PREDICT]/Sunnybrook ICH CTA Study Group and the Virtual International Stroke Trials Archive (VISTA)-ICH Collaborators.

Crit Care Med. 2018 Apr;46(4):e310-e317. doi: 10.1097/CCM.0000000000002962.


Effect of general anaesthesia on functional outcome in patients with anterior circulation ischaemic stroke having endovascular thrombectomy versus standard care: a meta-analysis of individual patient data.

Campbell BCV, van Zwam WH, Goyal M, Menon BK, Dippel DWJ, Demchuk AM, Bracard S, White P, Dávalos A, Majoie CBLM, van der Lugt A, Ford GA, de la Ossa NP, Kelly M, Bourcier R, Donnan GA, Roos YBWEM, Bang OY, Nogueira RG, Devlin TG, van den Berg LA, Clarençon F, Burns P, Carpenter J, Berkhemer OA, Yavagal DR, Pereira VM, Ducrocq X, Dixit A, Quesada H, Epstein J, Davis SM, Jansen O, Rubiera M, Urra X, Micard E, Lingsma HF, Naggara O, Brown S, Guillemin F, Muir KW, van Oostenbrugge RJ, Saver JL, Jovin TG, Hill MD, Mitchell PJ; HERMES collaborators.

Lancet Neurol. 2018 Jan;17(1):47-53. doi: 10.1016/S1474-4422(17)30407-6. Epub 2017 Dec 16.


Time for a Time Window Extension: Insights from Late Presenters in the ESCAPE Trial.

Evans JW, Graham BR, Pordeli P, Al-Ajlan FS, Willinsky R, Montanera WJ, Rempel JL, Shuaib A, Brennan P, Williams D, Roy D, Poppe AY, Jovin TG, Devlin T, Baxter BW, Krings T, Silver FL, Frei DF, Fanale C, Tampieri D, Teitelbaum J, Iancu D, Shankar J, Barber PA, Demchuk AM, Goyal M, Hill MD, Menon BK; ESCAPE Trial Investigators.

AJNR Am J Neuroradiol. 2018 Jan;39(1):102-106. doi: 10.3174/ajnr.A5462. Epub 2017 Nov 30.


Canadian stroke best practice consensus statement: Secondary stroke prevention during pregnancy.

Swartz RH, Ladhani NNN, Foley N, Nerenberg K, Bal S, Barrett J, Bushnell C, Chan WS, Chari R, Dowlatshahi D, Amrani ME, Gandhi S, Gubitz G, Hill MD, James A, Jeerakathil T, Jin A, Kirton A, Lanthier S, Lausman A, Leffert LR, Mandzia J, Menon B, Pikula A, Poppe A, Potts J, Ray J, Saposnik G, Sharma M, Smith EE, Bhogal S, Smitko E, Lindsay MP; Heart and Stroke Foundation Canadian Stroke Best Practice Advisory Committees.

Int J Stroke. 2018 Jun;13(4):406-419. doi: 10.1177/1747493017743801. Epub 2017 Nov 24.


Do Intracerebral Hemorrhage Nonexpanders Actually Expand Into the Ventricular Space?

Dowlatshahi D, Deshpande A, Aviv RI, Rodriguez-Luna D, Molina CA, Blas YS, Dzialowski I, Kobayashi A, Boulanger JM, Lum C, Gubitz GJ, Padma V, Roy J, Kase CS, Bhatia R, Hill MD, Demchuk AM; PREDICT ICH CTA Study Group.

Stroke. 2018 Jan;49(1):201-203. doi: 10.1161/STROKEAHA.117.018716. Epub 2017 Nov 22.


Thrombolysis: Improving door-to-needle times for ischemic stroke treatment - A narrative review.

Kamal N, Smith EE, Jeerakathil T, Hill MD.

Int J Stroke. 2018 Apr;13(3):268-276. doi: 10.1177/1747493017743060. Epub 2017 Nov 15.


A composite robotic-based measure of upper limb proprioception.

Kenzie JM, Semrau JA, Hill MD, Scott SH, Dukelow SP.

J Neuroeng Rehabil. 2017 Nov 13;14(1):114. doi: 10.1186/s12984-017-0329-8.


Minimal sufficient balance randomization for sequential randomized controlled trial designs: results from the ESCAPE trial.

Sajobi TT, Singh G, Lowerison MW, Engbers J, Menon BK, Demchuk AM, Goyal M, Hill MD.

Trials. 2017 Nov 2;18(1):516. doi: 10.1186/s13063-017-2264-1.


Temporal Trends in the Use and Comparative Effectiveness of Direct Oral Anticoagulant Agents Versus Warfarin for Nonvalvular Atrial Fibrillation: A Canadian Population-Based Study.

Yu AYX, Malo S, Svenson LW, Wilton SB, Hill MD.

J Am Heart Assoc. 2017 Oct 28;6(11). pii: e007129. doi: 10.1161/JAHA.117.007129.


Diffusion-Weighted MRI Stroke Volume Following Recanalization Treatment is Threshold-Dependent.

Sah RG, d'Esterre CD, Hill MD, Hafeez M, Tariq S, Forkert ND, Demchuk AM, Goyal M, Barber PA.

Clin Neuroradiol. 2017 Oct 19. doi: 10.1007/s00062-017-0634-4. [Epub ahead of print]


Design and synthesis of a novel series of (1'S,2R,4'S)-3H-4'-azaspiro[benzo[4,5]imidazo[2,1-b]oxazole-2,2'-bicyclo[2.2.2]octanes] with high affinity for the α7 neuronal nicotinic receptor.

Cook J, Zusi FC, Hill MD, Fang H, Pearce B, Park H, Gallagher L, McDonald IM, Bristow L, Macor JE, Olson RE.

Bioorg Med Chem Lett. 2017 Nov 15;27(22):5002-5005. doi: 10.1016/j.bmcl.2017.10.009. Epub 2017 Oct 10.


Population-based study of home-time by stroke type and correlation with modified Rankin score.

Yu AYX, Rogers E, Wang M, Sajobi TT, Coutts SB, Menon BK, Hill MD, Smith EE.

Neurology. 2017 Nov 7;89(19):1970-1976. doi: 10.1212/WNL.0000000000004631. Epub 2017 Oct 11.


Acute ischemic stroke with tandem lesions: technical endovascular management and clinical outcomes from the ESCAPE trial.

Assis Z, Menon BK, Goyal M, Demchuk AM, Shankar J, Rempel JL, Roy D, Poppe AY, Yang V, Lum C, Dowlatshahi D, Thornton J, Choe H, Burns PA, Frei DF, Baxter BW, Hill MD; ESCAPE Trialists.

J Neurointerv Surg. 2018 May;10(5):429-433. doi: 10.1136/neurintsurg-2017-013316. Epub 2017 Oct 11.


Moderate sensitivity and high specificity of emergency department administrative data for transient ischemic attacks.

Yu AYX, Quan H, McRae A, Wagner GO, Hill MD, Coutts SB.

BMC Health Serv Res. 2017 Sep 18;17(1):666. doi: 10.1186/s12913-017-2612-6.


Secondary prevention treatment after acute stroke in older South Asian, Chinese and other Canadians: a retrospective data analysis.

Khan NA, McAlister FA, Pilote L, Palepu A, Quan H, Hill MD, Fang J, Kapral MK.

CMAJ Open. 2017 Sep 11;5(3):E702-E709. doi: 10.9778/cmajo.20160147.


Outcomes of endovascular treatment for acute large-vessel ischaemic stroke more than 6 h after symptom onset.

Motyer R, Kok HK, Asadi H, O'Hare A, Brennan P, Power S, Looby S, Nicholson P, Williams D, Murphy S, Hill MD, Goyal M, McManus J, O'Brien P, Thornton J.

J Intern Med. 2017 Dec;282(6):537-545. doi: 10.1111/joim.12680. Epub 2017 Sep 25.


A randomised controlled trial assessing the efficacy of an electronic discharge communication tool for preventing death or hospital readmission.

Santana MJ, Holroyd-Leduc J, Southern DA, Flemons WW, O'Beirne M, Hill MD, Forster AJ, White DE, Ghali WA; e-DCT Team.

BMJ Qual Saf. 2017 Dec;26(12):993-1003. doi: 10.1136/bmjqs-2017-006635. Epub 2017 Aug 18.


Hospital treatment costs and length of stay associated with hypertension and multimorbidity after hemorrhagic stroke.

Specogna AV, Turin TC, Patten SB, Hill MD.

BMC Neurol. 2017 Aug 10;17(1):158. doi: 10.1186/s12883-017-0930-2.


Consumer-Based Physical Activity Monitor as a Practical Way to Measure Walking Intensity During Inpatient Stroke Rehabilitation.

Klassen TD, Semrau JA, Dukelow SP, Bayley MT, Hill MD, Eng JJ.

Stroke. 2017 Sep;48(9):2614-2617. doi: 10.1161/STROKEAHA.117.018175. Epub 2017 Aug 7.


Subclinical Atrial Fibrillation in Older Patients.

Healey JS, Alings M, Ha A, Leong-Sit P, Birnie DH, de Graaf JJ, Freericks M, Verma A, Wang J, Leong D, Dokainish H, Philippon F, Barake W, McIntyre WF, Simek K, Hill MD, Mehta SR, Carlson M, Smeele F, Pandey AS, Connolly SJ; ASSERT-II Investigators.

Circulation. 2017 Oct 3;136(14):1276-1283. doi: 10.1161/CIRCULATIONAHA.117.028845. Epub 2017 Aug 4.


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