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Items: 25

1.

Interdisciplinary pharmaceutical sciences activity within a pharmacy practice skills course.

Brown KP, Raccor BS, Hilgers RH, Breivogel CS.

Curr Pharm Teach Learn. 2019 Mar;11(3):270-276. doi: 10.1016/j.cptl.2018.12.009. Epub 2018 Dec 27.

PMID:
30904149
2.

Thioredoxin reverses age-related hypertension by chronically improving vascular redox and restoring eNOS function.

Hilgers RH, Kundumani-Sridharan V, Subramani J, Chen LC, Cuello LG, Rusch NJ, Das KC.

Sci Transl Med. 2017 Feb 8;9(376). pii: eaaf6094. doi: 10.1126/scitranslmed.aaf6094.

3.

Thioredoxin Uses a GSH-independent Route to Deglutathionylate Endothelial Nitric-oxide Synthase and Protect against Myocardial Infarction.

Subramani J, Kundumani-Sridharan V, Hilgers RH, Owens C, Das KC.

J Biol Chem. 2016 Nov 4;291(45):23374-23389. Epub 2016 Sep 1.

4.

Role of in vivo vascular redox in resistance arteries.

Hilgers RH, Das KC.

Hypertension. 2015 Jan;65(1):130-9. doi: 10.1161/HYPERTENSIONAHA.114.04473. Epub 2014 Oct 13.

5.

Endothelial cell transfusion ameliorates endothelial dysfunction in 5/6 nephrectomized rats.

Pacurari M, Xing D, Hilgers RH, Guo YY, Yang Z, Hage FG.

Am J Physiol Heart Circ Physiol. 2013 Oct 15;305(8):H1256-64. doi: 10.1152/ajpheart.00132.2013. Epub 2013 Aug 16.

6.

Vasorelaxing effects of estetrol in rat arteries.

Hilgers RH, Oparil S, Wouters W, Coelingh Bennink HJ.

J Endocrinol. 2012 Oct;215(1):97-106. doi: 10.1530/JOE-12-0009. Epub 2012 Jul 13.

PMID:
22798015
7.

Acute O-GlcNAcylation prevents inflammation-induced vascular dysfunction.

Hilgers RH, Xing D, Gong K, Chen YF, Chatham JC, Oparil S.

Am J Physiol Heart Circ Physiol. 2012 Sep 1;303(5):H513-22. doi: 10.1152/ajpheart.01175.2011. Epub 2012 Jul 9.

8.

cGMP inhibits TGF-beta signaling by sequestering Smad3 with cytosolic beta2-tubulin in pulmonary artery smooth muscle cells.

Gong K, Xing D, Li P, Hilgers RH, Hage FG, Oparil S, Chen YF.

Mol Endocrinol. 2011 Oct;25(10):1794-803. doi: 10.1210/me.2011-1009. Epub 2011 Aug 25.

9.

Interleukin-10 inhibits the in vivo and in vitro adverse effects of TNF-alpha on the endothelium of murine aorta.

Zemse SM, Chiao CW, Hilgers RH, Webb RC.

Am J Physiol Heart Circ Physiol. 2010 Oct;299(4):H1160-7. doi: 10.1152/ajpheart.00763.2009. Epub 2010 Jul 16.

10.

Twenty-four-hour exposure to altered blood flow modifies endothelial Ca2+-activated K+ channels in rat mesenteric arteries.

Hilgers RH, Janssen GM, Fazzi GE, De Mey JG.

J Pharmacol Exp Ther. 2010 Apr;333(1):210-7. doi: 10.1124/jpet.109.161448. Epub 2009 Dec 29.

PMID:
20040579
11.

Myoendothelial coupling in the mesenteric arterial bed; segmental differences and interplay between nitric oxide and endothelin-1.

Hilgers RH, De Mey JG.

Br J Pharmacol. 2009 Apr;156(8):1239-47. doi: 10.1111/j.1476-5381.2009.00128.x. Epub 2009 Mar 19.

12.

Restoration of endothelin-1-induced impairment in endothelium-dependent relaxation by interleukin-10 in murine aortic rings.

Zemse SM, Hilgers RH, Simkins GB, Rudic RD, Webb RC.

Can J Physiol Pharmacol. 2008 Aug;86(8):557-65. doi: 10.1139/Y08-049.

13.
14.

Interleukin-10 counteracts impaired endothelium-dependent relaxation induced by ANG II in murine aortic rings.

Zemse SM, Hilgers RH, Webb RC.

Am J Physiol Heart Circ Physiol. 2007 Jun;292(6):H3103-8. Epub 2007 Feb 23.

15.

Reduced expression of SKCa and IKCa channel proteins in rat small mesenteric arteries during angiotensin II-induced hypertension.

Hilgers RH, Webb RC.

Am J Physiol Heart Circ Physiol. 2007 May;292(5):H2275-84. Epub 2007 Jan 5.

16.

Two-photon microscopy of vital murine elastic and muscular arteries. Combined structural and functional imaging with subcellular resolution.

Megens RT, Reitsma S, Schiffers PH, Hilgers RH, De Mey JG, Slaaf DW, oude Egbrink MG, van Zandvoort MA.

J Vasc Res. 2007;44(2):87-98. Epub 2006 Dec 28.

PMID:
17192719
17.

Increased RhoA/Rho-kinase signaling mediates spontaneous tone in aorta from angiotensin II-induced hypertensive rats.

Jin L, Ying Z, Hilgers RH, Yin J, Zhao X, Imig JD, Webb RC.

J Pharmacol Exp Ther. 2006 Jul;318(1):288-95. Epub 2006 Mar 28.

PMID:
16569756
18.

Regional heterogeneity in acetylcholine-induced relaxation in rat vascular bed: role of calcium-activated K+ channels.

Hilgers RH, Todd J Jr, Webb RC.

Am J Physiol Heart Circ Physiol. 2006 Jul;291(1):H216-22. Epub 2006 Feb 10.

19.

Molecular aspects of arterial smooth muscle contraction: focus on Rho.

Hilgers RH, Webb RC.

Exp Biol Med (Maywood). 2005 Dec;230(11):829-35. Review.

PMID:
16339747
20.

Toward functional genomics of flow-induced outward remodeling of resistance arteries.

De Mey JG, Schiffers PM, Hilgers RH, Sanders MM.

Am J Physiol Heart Circ Physiol. 2005 Mar;288(3):H1022-7. Review.

21.

Flow-dependent dilation mediated by endogenous kinins requires angiotensin AT2 receptors.

Bergaya S, Hilgers RH, Meneton P, Dong Y, Bloch-Faure M, Inagami T, Alhenc-Gelas F, Lévy BI, Boulanger CM.

Circ Res. 2004 Jun 25;94(12):1623-9. Epub 2004 May 6.

PMID:
15131008
22.

Tissue angiotensin-converting enzyme in imposed and physiological flow-related arterial remodeling in mice.

Hilgers RH, Schiffers PM, Aartsen WM, Fazzi GE, Smits JF, De Mey JG.

Arterioscler Thromb Vasc Biol. 2004 May;24(5):892-7. Epub 2004 Mar 18.

PMID:
15031129
23.

Changes in vascular distensibility during angiotensin-converting enzyme inhibition involve bradykinin type 2 receptors.

Aartsen WM, Hilgers RH, Schiffers PM, Daemen MJ, De Mey JG, Smits JF.

J Vasc Res. 2004 Jan-Feb;41(1):18-27. Epub 2004 Jan 12.

PMID:
14726629
24.

Uterine artery structural and functional changes during pregnancy in tissue kallikrein-deficient mice.

Hilgers RH, Bergaya S, Schiffers PM, Meneton P, Boulanger CM, Henrion D, Lévy BI, De Mey JG.

Arterioscler Thromb Vasc Biol. 2003 Oct 1;23(10):1826-32. Epub 2003 Aug 21.

PMID:
12933530
25.

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