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Items: 1 to 50 of 85

1.

Hypertrophy of human embryonic stem cell-derived cardiomyocytes supported by positive feedback between Ca2+ and diacylglycerol signals.

Deisl C, Fine M, Moe OW, Hilgemann DW.

Pflugers Arch. 2019 Aug;471(8):1143-1157. doi: 10.1007/s00424-019-02293-0. Epub 2019 Jun 28.

2.

On the existence of endocytosis driven by membrane phase separations.

Hilgemann DW, Lin MJ, Fine M, Deisl C.

Biochim Biophys Acta Biomembr. 2019 Jun 13. pii: S0005-2736(19)30138-5. doi: 10.1016/j.bbamem.2019.06.006. [Epub ahead of print] Review.

3.

Author Correction: TMEM16F activation by Ca2+ triggers plasma membrane expansion and directs PD-1 trafficking.

Bricogne C, Fine M, Pereira PM, Sung J, Tijani M, Wang Y, Henriques R, Collins MK, Hilgemann DW.

Sci Rep. 2019 May 17;9(1):7705. doi: 10.1038/s41598-019-43808-0.

4.

TMEM16F activation by Ca2+ triggers plasma membrane expansion and directs PD-1 trafficking.

Bricogne C, Fine M, Pereira PM, Sung J, Tijani M, Wang Y, Henriques R, Collins MK, Hilgemann DW.

Sci Rep. 2019 Jan 24;9(1):619. doi: 10.1038/s41598-018-37056-x. Erratum in: Sci Rep. 2019 May 17;9(1):7705.

5.

Correction: Lipid signaling to membrane proteins: From second messengers to membrane domains and adapter-free endocytosis.

Hilgemann DW, Dai G, Collins A, Lariccia V, Magi S, Deisl C, Fine M.

J Gen Physiol. 2018 Feb 5;150(2):367. doi: 10.1085/jgp.20171187501122018c. Epub 2018 Jan 16. No abstract available.

6.

Lipid signaling to membrane proteins: From second messengers to membrane domains and adapter-free endocytosis.

Hilgemann DW, Dai G, Collins A, Lariccia V, Magi S, Deisl C, Fine M.

J Gen Physiol. 2018 Feb 5;150(2):211-224. doi: 10.1085/jgp.201711875. Epub 2018 Jan 11. Review. Erratum in: J Gen Physiol. 2018 Jan 16;:.

7.
8.

Soluble klotho binds monosialoganglioside to regulate membrane microdomains and growth factor signaling.

Dalton G, An SW, Al-Juboori SI, Nischan N, Yoon J, Dobrinskikh E, Hilgemann DW, Xie J, Luby-Phelps K, Kohler JJ, Birnbaumer L, Huang CL.

Proc Natl Acad Sci U S A. 2017 Jan 24;114(4):752-757. doi: 10.1073/pnas.1620301114. Epub 2017 Jan 9.

9.

Profound regulation of Na/K pump activity by transient elevations of cytoplasmic calcium in murine cardiac myocytes.

Lu FM, Deisl C, Hilgemann DW.

Elife. 2016 Sep 14;5. pii: e19267. doi: 10.7554/eLife.19267.

10.

S-palmitoylation and the regulation of NCX1.

Fuller W, Reilly L, Hilgemann DW.

Channels (Austin). 2016;10(2):75-7. doi: 10.1080/19336950.2015.1099329. Epub 2015 Sep 29. No abstract available.

11.

Palmitoylation of the Na/Ca exchanger cytoplasmic loop controls its inactivation and internalization during stress signaling.

Reilly L, Howie J, Wypijewski K, Ashford ML, Hilgemann DW, Fuller W.

FASEB J. 2015 Nov;29(11):4532-43. doi: 10.1096/fj.15-276493. Epub 2015 Jul 14.

12.

Cardiac electrophysiology delivered a "grand slam" by angiotensin II: the third explanation of transmural cardiac electrical activity gradients.

Hilgemann DW.

Biophys J. 2014 Jun 3;106(11):2288-90. doi: 10.1016/j.bpj.2014.04.043. No abstract available.

13.

Fishing for holes in transporters: how protons breach the Na/K pump security gates.

Hilgemann DW.

J Gen Physiol. 2014 Apr;143(4):437-41. doi: 10.1085/jgp.201411189. No abstract available.

14.

Massive palmitoylation-dependent endocytosis during reoxygenation of anoxic cardiac muscle.

Lin MJ, Fine M, Lu JY, Hofmann SL, Frazier G, Hilgemann DW.

Elife. 2013 Nov 26;2:e01295. doi: 10.7554/eLife.01295.

15.

Massive endocytosis triggered by surface membrane palmitoylation under mitochondrial control in BHK fibroblasts.

Hilgemann DW, Fine M, Linder ME, Jennings BC, Lin MJ.

Elife. 2013 Nov 26;2:e01293. doi: 10.7554/eLife.01293.

16.

Human-induced pluripotent stem cell-derived cardiomyocytes for studies of cardiac ion transporters.

Fine M, Lu FM, Lin MJ, Moe O, Wang HR, Hilgemann DW.

Am J Physiol Cell Physiol. 2013 Sep;305(5):C481-91. doi: 10.1152/ajpcell.00143.2013. Epub 2013 Jun 26.

17.

Toward an understanding of the complete NCX1 lifetime in the cardiac sarcolemma.

Hilgemann DW, Lin MJ, Fine M, Frazier G, Wang HR.

Adv Exp Med Biol. 2013;961:345-52. doi: 10.1007/978-1-4614-4756-6_29. Review.

PMID:
23224893
18.

Fitting K(V) potassium channels into the PIP(2) puzzle: Hille group connects dots between illustrious HH groups.

Hilgemann DW.

J Gen Physiol. 2012 Sep;140(3):245-8. doi: 10.1085/jgp.201210874. No abstract available.

19.

Massive endocytosis driven by lipidic forces originating in the outer plasmalemmal monolayer: a new approach to membrane recycling and lipid domains.

Fine M, Llaguno MC, Lariccia V, Lin MJ, Yaradanakul A, Hilgemann DW.

J Gen Physiol. 2011 Feb;137(2):137-54. doi: 10.1085/jgp.201010469. Epub 2011 Jan 17.

20.

Mechanistic analysis of massive endocytosis in relation to functionally defined surface membrane domains.

Hilgemann DW, Fine M.

J Gen Physiol. 2011 Feb;137(2):155-72. doi: 10.1085/jgp.201010470. Epub 2011 Jan 17.

21.

Massive calcium-activated endocytosis without involvement of classical endocytic proteins.

Lariccia V, Fine M, Magi S, Lin MJ, Yaradanakul A, Llaguno MC, Hilgemann DW.

J Gen Physiol. 2011 Jan;137(1):111-32. doi: 10.1085/jgp.201010468.

22.

Steady-state function of the ubiquitous mammalian Na/H exchanger (NHE1) in relation to dimer coupling models with 2Na/2H stoichiometry.

Fuster D, Moe OW, Hilgemann DW.

J Gen Physiol. 2008 Oct;132(4):465-80. doi: 10.1085/jgp.200810016. Erratum in: J Gen Physiol. 2009 Mar;133(3):345.

23.

Ca-dependent nonsecretory vesicle fusion in a secretory cell.

Wang TM, Hilgemann DW.

J Gen Physiol. 2008 Jul;132(1):51-65. doi: 10.1085/jgp.200709950. Epub 2008 Jun 18.

24.

Massive Ca-induced membrane fusion and phospholipid changes triggered by reverse Na/Ca exchange in BHK fibroblasts.

Yaradanakul A, Wang TM, Lariccia V, Lin MJ, Shen C, Liu X, Hilgemann DW.

J Gen Physiol. 2008 Jul;132(1):29-50. doi: 10.1085/jgp.200709865. Epub 2008 Jun 18.

25.

Unrestricted diffusion of exogenous and endogenous PIP(2 )in baby hamster kidney and Chinese hamster ovary cell plasmalemma.

Yaradanakul A, Hilgemann DW.

J Membr Biol. 2007 Dec;220(1-3):53-67. Epub 2007 Nov 16. Erratum in: J Membr Biol. 2008 Feb;221(3):175.

PMID:
18008024
26.

Dual control of cardiac Na+ Ca2+ exchange by PIP(2): electrophysiological analysis of direct and indirect mechanisms.

Yaradanakul A, Feng S, Shen C, Lariccia V, Lin MJ, Yang J, Kang T M, Dong P, Yin HL, Albanesi JP, Hilgemann DW.

J Physiol. 2007 Aug 1;582(Pt 3):991-1010. Epub 2007 May 31.

27.

Dual control of cardiac Na+ Ca2+ exchange by PIP(2): analysis of the surface membrane fraction by extracellular cysteine PEGylation.

Shen C, Lin MJ, Yaradanakul A, Lariccia V, Hill JA, Hilgemann DW.

J Physiol. 2007 Aug 1;582(Pt 3):1011-26. Epub 2007 May 31.

28.

Local PIP(2) signals: when, where, and how?

Hilgemann DW.

Pflugers Arch. 2007 Oct;455(1):55-67. Epub 2007 May 30. Review.

PMID:
17534652
30.

Angiotensin II regulates neuronal excitability via phosphatidylinositol 4,5-bisphosphate-dependent modulation of Kv7 (M-type) K+ channels.

Zaika O, Lara LS, Gamper N, Hilgemann DW, Jaffe DB, Shapiro MS.

J Physiol. 2006 Aug 15;575(Pt 1):49-67. Epub 2006 Jun 15.

31.

Molecular control of cardiac sodium homeostasis in health and disease.

Hilgemann DW, Yaradanakul A, Wang Y, Fuster D.

J Cardiovasc Electrophysiol. 2006 May;17 Suppl 1:S47-S56. Review.

PMID:
16686682
32.

Regulation of Kv7 (KCNQ) K+ channel open probability by phosphatidylinositol 4,5-bisphosphate.

Li Y, Gamper N, Hilgemann DW, Shapiro MS.

J Neurosci. 2005 Oct 26;25(43):9825-35.

33.

Phospholipase C in living cells: activation, inhibition, Ca2+ requirement, and regulation of M current.

Horowitz LF, Hirdes W, Suh BC, Hilgemann DW, Mackie K, Hille B.

J Gen Physiol. 2005 Sep;126(3):243-62.

34.

New insights into the molecular and cellular workings of the cardiac Na+/Ca2+ exchanger.

Hilgemann DW.

Am J Physiol Cell Physiol. 2004 Nov;287(5):C1167-72. Review.

35.

Lipid- and mechanosensitivities of sodium/hydrogen exchangers analyzed by electrical methods.

Fuster D, Moe OW, Hilgemann DW.

Proc Natl Acad Sci U S A. 2004 Jul 13;101(28):10482-7. Epub 2004 Jul 6.

36.

Biochemistry. Oily barbarians breach ion channel gates.

Hilgemann DW.

Science. 2004 Apr 9;304(5668):223-4. Epub 2004 Mar 18. No abstract available.

PMID:
15031439
37.

Multiple transport modes of the cardiac Na+/Ca2+ exchanger.

Kang TM, Hilgemann DW.

Nature. 2004 Feb 5;427(6974):544-8.

PMID:
14765196
38.
39.

Protein kinase C inhibits ROMK1 channel activity via a phosphatidylinositol 4,5-bisphosphate-dependent mechanism.

Zeng WZ, Li XJ, Hilgemann DW, Huang CL.

J Biol Chem. 2003 May 9;278(19):16852-6. Epub 2003 Mar 3.

40.

From a pump to a pore: how palytoxin opens the gates.

Hilgemann DW.

Proc Natl Acad Sci U S A. 2003 Jan 21;100(2):386-8. Epub 2003 Jan 13. No abstract available.

41.

Getting ready for the decade of the lipids.

Hilgemann DW.

Annu Rev Physiol. 2003;65:697-700. Epub 2002 May 1. Review. No abstract available.

PMID:
12517999
42.

Sodium-calcium exchange stoichiometry: is the noose tightening?

Kang TM, Steciuk M, Hilgemann DW.

Ann N Y Acad Sci. 2002 Nov;976:142-51; discussion 152-3.

PMID:
12502553
43.

Modulation of cardiac PIP2 by cardioactive hormones and other physiologically relevant interventions.

Nasuhoglu C, Feng S, Mao Y, Shammat I, Yamamato M, Earnest S, Lemmon M, Hilgemann DW.

Am J Physiol Cell Physiol. 2002 Jul;283(1):C223-34.

44.

Nonradioactive analysis of phosphatidylinositides and other anionic phospholipids by anion-exchange high-performance liquid chromatography with suppressed conductivity detection.

Nasuhoglu C, Feng S, Mao J, Yamamoto M, Yin HL, Earnest S, Barylko B, Albanesi JP, Hilgemann DW.

Anal Biochem. 2002 Feb 15;301(2):243-54.

PMID:
11814295
45.

The complex and intriguing lives of PIP2 with ion channels and transporters.

Hilgemann DW, Feng S, Nasuhoglu C.

Sci STKE. 2001 Dec 4;2001(111):re19. Review.

PMID:
11734659
46.

Do phosphatidylinositides modulate vertebrate phototransduction?

Womack KB, Gordon SE, He F, Wensel TG, Lu CC, Hilgemann DW.

J Neurosci. 2000 Apr 15;20(8):2792-9.

47.

Interaction of PIP(2) with the XIP region of the cardiac Na/Ca exchanger.

He Z, Feng S, Tong Q, Hilgemann DW, Philipson KD.

Am J Physiol Cell Physiol. 2000 Apr;278(4):C661-6.

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