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Items: 1 to 50 of 95

1.

Decellularization combined with enzymatic removal of N-linked glycans and residual DNA reduces inflammatory response and improves performance of porcine xenogeneic pulmonary heart valves in an ovine in vivo model.

Ramm R, Goecke T, Theodoridis K, Hoeffler K, Sarikouch S, Findeisen K, Ciubotaru A, Cebotari S, Tudorache I, Haverich A, Hilfiker A.

Xenotransplantation. 2019 Nov 26:e12571. doi: 10.1111/xen.12571. [Epub ahead of print]

PMID:
31769101
2.

Asparagine Synthesis During Tobacco Leaf Curing.

Bovet L, Cheval C, Hilfiker A, Battey J, Langlet D, Broye H, Schwaar J, Ozelley P, Lang G, Bakaher N, Laparra H, Goepfert S.

Plants (Basel). 2019 Nov 11;8(11). pii: E492. doi: 10.3390/plants8110492.

3.

Decellularized pig pulmonary heart valves-Depletion of nucleic acids measured by proviral PERV pol.

Godehardt AW, Ramm R, Gulich B, Tönjes RR, Hilfiker A.

Xenotransplantation. 2019 Nov 6:e12565. doi: 10.1111/xen.12565. [Epub ahead of print]

PMID:
31692126
4.

Assessment of cytocompatibility and mechanical properties of detergent-decellularized ovine pericardial tissue.

Mogaldea A, Theodoridis K, Goecke T, Tudorache I, Haverich A, Cebotari S, Hilfiker A.

Int J Artif Organs. 2019 Nov;42(11):628-635. doi: 10.1177/0391398819850583. Epub 2019 May 24.

PMID:
31126200
5.

Effects of personalized endurance training on cellular age and vascular function in middle-aged sedentary women.

Eigendorf J, Melk A, Haufe S, Boethig D, Berliner D, Kerling A, Kueck M, Stenner H, Bara C, Stiesch M, Schippert C, Hilfiker A, Falk C, Bauersachs J, Thum T, Lichtinghagen R, Haverich A, Hilfiker-Kleiner D, Tegtbur U.

Eur J Prev Cardiol. 2019 Nov;26(17):1903-1906. doi: 10.1177/2047487319849505. Epub 2019 May 13. No abstract available.

PMID:
31084260
6.

Formation of three-dimensional tubular endothelial cell networks under defined serum-free cell culture conditions in human collagen hydrogels.

Andrée B, Ichanti H, Kalies S, Heisterkamp A, Strauß S, Vogt PM, Haverich A, Hilfiker A.

Sci Rep. 2019 Apr 1;9(1):5437. doi: 10.1038/s41598-019-41985-6.

7.

Early Insight Into In Vivo Recellularization of Cell-Free Allogenic Heart Valves.

Sarikouch S, Theodoridis K, Hilfiker A, Boethig D, Laufer G, Andreas M, Cebotari S, Tudorache I, Bobylev D, Neubert L, Teiken K, Robertus JL, Jonigk D, Beerbaum P, Haverich A, Horke A.

Ann Thorac Surg. 2019 Aug;108(2):581-589. doi: 10.1016/j.athoracsur.2019.02.058. Epub 2019 Mar 28.

8.

Identification of miR-143 as a Major Contributor for Human Stenotic Aortic Valve Disease.

Fiedler J, Park DH, Hobuß L, Anaraki PK, Pfanne A, Just A, Mitzka S, Dumler I, Weidemann F, Hilfiker A, Thum T.

J Cardiovasc Transl Res. 2019 Oct;12(5):447-458. doi: 10.1007/s12265-019-09880-7. Epub 2019 Mar 6.

PMID:
30840186
9.

Spectral fingerprinting of decellularized heart valve scaffolds.

Vásquez-Rivera A, Oldenhof H, Hilfiker A, Wolkers WF.

Spectrochim Acta A Mol Biomol Spectrosc. 2019 May 5;214:95-102. doi: 10.1016/j.saa.2019.02.006. Epub 2019 Feb 5.

PMID:
30769156
10.

Use of sucrose to diminish pore formation in freeze-dried heart valves.

Vásquez-Rivera A, Oldenhof H, Dipresa D, Goecke T, Kouvaka A, Will F, Haverich A, Korossis S, Hilfiker A, Wolkers WF.

Sci Rep. 2018 Aug 28;8(1):12982. doi: 10.1038/s41598-018-31388-4.

11.

Dehydration improves biomechanical strength of bioartificial vascular graft material and allows its long-term storage.

Aper T, Wilhelmi M, Boer U, Lau S, Benecke N, Hilfiker A, Haverich A.

Innov Surg Sci. 2018 Jul 23;3(3):215-224. doi: 10.1515/iss-2018-0017. eCollection 2018 Sep.

12.

Human adipose tissue-derived stromal cells in combination with exogenous stimuli facilitate three-dimensional network formation of human endothelial cells derived from various sources.

Manikowski D, Andrée B, Samper E, Saint-Marc C, Olmer R, Vogt P, Strauß S, Haverich A, Hilfiker A.

Vascul Pharmacol. 2018 Jul;106:28-36. doi: 10.1016/j.vph.2018.02.003. Epub 2018 Feb 13.

PMID:
29452238
13.

Decellularized mitral valve in a long-term sheep model.

Iablonskii P, Cebotari S, Ciubotaru A, Sarikouch S, Hoeffler K, Hilfiker A, Haverich A, Tudorache I.

Eur J Cardiothorac Surg. 2018 Jun 1;53(6):1165-1172. doi: 10.1093/ejcts/ezx485.

PMID:
29385428
14.

Simultaneous monitoring of different vitrification solution components permeating into tissues.

Vásquez-Rivera A, Sommer KK, Oldenhof H, Higgins AZ, Brockbank KGM, Hilfiker A, Wolkers WF.

Analyst. 2018 Jan 15;143(2):420-428. doi: 10.1039/c7an01576c.

PMID:
29236110
15.

In vivo performance of freeze-dried decellularized pulmonary heart valve allo- and xenografts orthotopically implanted into juvenile sheep.

Goecke T, Theodoridis K, Tudorache I, Ciubotaru A, Cebotari S, Ramm R, Höffler K, Sarikouch S, Vásquez Rivera A, Haverich A, Wolkers WF, Hilfiker A.

Acta Biomater. 2018 Mar 1;68:41-52. doi: 10.1016/j.actbio.2017.11.041. Epub 2017 Dec 2.

PMID:
29191508
16.

* Six-Year-Old Sheep as a Clinically Relevant Large Animal Model for Aortic Valve Replacement Using Tissue-Engineered Grafts Based on Decellularized Allogenic Matrix.

Theodoridis K, Tudorache I, Cebotari S, Calistru A, Meyer T, Sarikouch S, Bara C, Haverich A, Hilfiker A.

Tissue Eng Part C Methods. 2017 Dec;23(12):953-963. doi: 10.1089/ten.tec.2017.0163. Epub 2017 Nov 3.

PMID:
28922978
17.

Targeting Endothelial Cells with Multifunctional GaN/Fe Nanoparticles.

Braniste T, Tiginyanu I, Horvath T, Raevschi S, Andrée B, Cebotari S, Boyle EC, Haverich A, Hilfiker A.

Nanoscale Res Lett. 2017 Aug 10;12(1):486. doi: 10.1186/s11671-017-2262-y.

18.

Tissue Engineering of Vein Valves Based on Decellularized Natural Matrices.

Mogaldea A, Goecke T, Theodoridis K, Haverich A, Cebotari S, Hilfiker A.

Cells Tissues Organs. 2017;204(3-4):199-209. doi: 10.1159/000477776. Epub 2017 Aug 5.

PMID:
28787732
19.

Outgrowing endothelial and smooth muscle cells for tissue engineering approaches.

Kolster M, Wilhelmi M, Schrimpf C, Hilfiker A, Haverich A, Aper T.

J Tissue Eng. 2017 Mar 15;8:2041731417698852. doi: 10.1177/2041731417698852. eCollection 2017 Jan-Dec.

20.

Development and Characterization of a Porcine Mitral Valve Scaffold for Tissue Engineering.

Granados M, Morticelli L, Andriopoulou S, Kalozoumis P, Pflaum M, Iablonskii P, Glasmacher B, Harder M, Hegermann J, Wrede C, Tudorache I, Cebotari S, Hilfiker A, Haverich A, Korossis S.

J Cardiovasc Transl Res. 2017 Aug;10(4):374-390. doi: 10.1007/s12265-017-9747-z. Epub 2017 May 1.

PMID:
28462436
21.

Viability and proliferation of endothelial cells upon exposure to GaN nanoparticles.

Braniste T, Tiginyanu I, Horvath T, Raevschi S, Cebotari S, Lux M, Haverich A, Hilfiker A.

Beilstein J Nanotechnol. 2016 Sep 23;7:1330-1337. eCollection 2016.

22.

Dosage Compensation in Drosophila-a Model for the Coordinate Regulation of Transcription.

Kuroda MI, Hilfiker A, Lucchesi JC.

Genetics. 2016 Oct;204(2):435-450. Review.

23.

Effects of combined cryopreservation and decellularization on the biomechanical, structural and biochemical properties of porcine pulmonary heart valves.

Theodoridis K, Müller J, Ramm R, Findeisen K, Andrée B, Korossis S, Haverich A, Hilfiker A.

Acta Biomater. 2016 Oct 1;43:71-77. doi: 10.1016/j.actbio.2016.07.013. Epub 2016 Jul 12.

PMID:
27422199
24.

Decellularized GGTA1-KO pig heart valves do not bind preformed human xenoantibodies.

Ramm R, Niemann H, Petersen B, Haverich A, Hilfiker A.

Basic Res Cardiol. 2016 Jul;111(4):39. doi: 10.1007/s00395-016-0560-7. Epub 2016 May 6.

PMID:
27154491
25.

In vitro maturation of large-scale cardiac patches based on a perfusable starter matrix by cyclic mechanical stimulation.

Lux M, Andrée B, Horvath T, Nosko A, Manikowski D, Hilfiker-Kleiner D, Haverich A, Hilfiker A.

Acta Biomater. 2016 Jan;30:177-187. doi: 10.1016/j.actbio.2015.11.006. Epub 2015 Nov 4.

PMID:
26546973
26.

Decellularized aortic allografts versus pulmonary autografts for aortic valve replacement in the growing sheep model: haemodynamic and morphological results at 20 months after implantation.

Tudorache I, Theodoridis K, Baraki H, Sarikouch S, Bara C, Meyer T, Höffler K, Hartung D, Hilfiker A, Haverich A, Cebotari S.

Eur J Cardiothorac Surg. 2016 Apr;49(4):1228-38. doi: 10.1093/ejcts/ezv362. Epub 2015 Oct 24.

PMID:
26503725
27.

Novel method for the generation of tissue-engineered vascular grafts based on a highly compacted fibrin matrix.

Aper T, Wilhelmi M, Gebhardt C, Hoeffler K, Benecke N, Hilfiker A, Haverich A.

Acta Biomater. 2016 Jan;29:21-32. doi: 10.1016/j.actbio.2015.10.012. Epub 2015 Oct 21.

PMID:
26472610
28.

No evidence for αGal epitope transfer from media containing FCS onto human endothelial cells in culture.

Ramm R, Hartmann T, Tudorache I, Haverich A, Hilfiker A.

Xenotransplantation. 2015 Sep-Oct;22(5):345-55. doi: 10.1111/xen.12183. Epub 2015 Aug 24.

PMID:
26301779
29.

Successful matrix guided tissue regeneration of decellularized pulmonary heart valve allografts in elderly sheep.

Theodoridis K, Tudorache I, Calistru A, Cebotari S, Meyer T, Sarikouch S, Bara C, Brehm R, Haverich A, Hilfiker A.

Biomaterials. 2015 Jun;52:221-8. doi: 10.1016/j.biomaterials.2015.02.023. Epub 2015 Feb 27.

PMID:
25818428
30.

Sucrose Diffusion in Decellularized Heart Valves for Freeze-Drying.

Wang S, Oldenhof H, Goecke T, Ramm R, Harder M, Haverich A, Hilfiker A, Wolkers WF.

Tissue Eng Part C Methods. 2015 Sep;21(9):922-31. doi: 10.1089/ten.TEC.2014.0681. Epub 2015 May 4.

PMID:
25809201
31.

Tissue-engineered mitral valve: morphology and biomechanics †.

Iablonskii P, Cebotari S, Tudorache I, Granados M, Morticelli L, Goecke T, Klein N, Korossis S, Hilfiker A, Haverich A.

Interact Cardiovasc Thorac Surg. 2015 Jun;20(6):712-9; discussion 719. doi: 10.1093/icvts/ivv039. Epub 2015 Mar 11.

PMID:
25762708
32.

[Prefabrication of heart valves].

Goecke T, Tudorache I, Hilfiker A, Haverich A, Cebotari S.

Chirurg. 2015 Mar;86(3):251-3. doi: 10.1007/s00104-014-2831-x. Review. German.

PMID:
25687813
33.

Investigation of inflammatory response of decellularized porcine aortic tissue in mice: can we rely on this experimental setting?

Goecke T, Hilfiker A, Haverich A, Cebotari S.

Eur J Cardiothorac Surg. 2015 Mar;47(3):e90-1. doi: 10.1093/ejcts/ezu487. Epub 2014 Dec 27. No abstract available.

PMID:
25543173
34.

Freeze-drying of decellularized heart valve tissues.

Wolkers WF, Hilfiker A.

Methods Mol Biol. 2015;1257:499-506. doi: 10.1007/978-1-4939-2193-5_26.

PMID:
25428026
35.

Successful re-endothelialization of a perfusable biological vascularized matrix (BioVaM) for the generation of 3D artificial cardiac tissue.

Andrée B, Bela K, Horvath T, Lux M, Ramm R, Venturini L, Ciubotaru A, Zweigerdt R, Haverich A, Hilfiker A.

Basic Res Cardiol. 2014;109(6):441. doi: 10.1007/s00395-014-0441-x. Epub 2014 Sep 18.

PMID:
25231595
36.

Improvement of biological age by physical activity.

Melk A, Tegtbur U, Hilfiker-Kleiner D, Eberhard J, Saretzki G, Eulert C, Kerling A, Nelius AK, Hömme M, Strunk D, Berliner D, Röntgen P, Kück M, Bauersachs J, Hilfiker A, Haverich A, Bara C, Stiesch M.

Int J Cardiol. 2014 Oct 20;176(3):1187-9. doi: 10.1016/j.ijcard.2014.07.236. Epub 2014 Aug 12. No abstract available.

PMID:
25223816
37.

BioVaM in the rat model: a new approach of vascularized 3D tissue for esophageal replacement.

Hofmann AD, Hilfiker A, Haverich A, Andree B, Kuebler J, Ure B.

Eur J Pediatr Surg. 2015 Apr;25(2):181-8. doi: 10.1055/s-0034-1370778. Epub 2014 May 2.

PMID:
24792863
38.

Transplantation of mucosa from stomach to esophagus to prevent stricture after circumferential endoscopic submucosal dissection of early squamous cell.

Hochberger J, Koehler P, Wedi E, Gluer S, Rothstein RI, Niemann H, Hilfiker A, Gonzalez S, Kruse E.

Gastroenterology. 2014 Apr;146(4):906-9. doi: 10.1053/j.gastro.2014.01.063. Epub 2014 Feb 8. No abstract available.

PMID:
24512802
39.

Protein stability in stored decellularized heart valve scaffolds and diffusion kinetics of protective molecules.

Wang S, Oldenhof H, Dai X, Haverich A, Hilfiker A, Harder M, Wolkers WF.

Biochim Biophys Acta. 2014 Feb;1844(2):430-8. doi: 10.1016/j.bbapap.2013.11.016. Epub 2013 Dec 7.

PMID:
24321313
40.

Isolation and chondrogenic differentiation of porcine perichondrial progenitor cells for the purpose of cartilage tissue engineering.

Derks M, Sturm T, Haverich A, Hilfiker A.

Cells Tissues Organs. 2013;198(3):179-89. doi: 10.1159/000354897. Epub 2013 Oct 18.

PMID:
24157487
41.

Moderate and severe periodontitis are independent risk factors associated with low cardiorespiratory fitness in sedentary non-smoking men aged between 45 and 65 years.

Eberhard J, Stiesch M, Kerling A, Bara C, Eulert C, Hilfiker-Kleiner D, Hilfiker A, Budde E, Bauersachs J, Kück M, Haverich A, Melk A, Tegtbur U.

J Clin Periodontol. 2014 Jan;41(1):31-7. doi: 10.1111/jcpe.12183. Epub 2013 Nov 13.

PMID:
24134735
42.

Generation of bioartificial heart tissue by combining a three-dimensional gel-based cardiac construct with decellularized small intestinal submucosa.

Vukadinovic-Nikolic Z, Andrée B, Dorfman SE, Pflaum M, Horvath T, Lux M, Venturini L, Bär A, Kensah G, Lara AR, Tudorache I, Cebotari S, Hilfiker-Kleiner D, Haverich A, Hilfiker A.

Tissue Eng Part A. 2014 Feb;20(3-4):799-809. doi: 10.1089/ten.TEA.2013.0184. Epub 2013 Nov 16.

PMID:
24102409
43.

Biological heart valves.

Ciubotaru A, Cebotari S, Tudorache I, Beckmann E, Hilfiker A, Haverich A.

Biomed Tech (Berl). 2013 Oct;58(5):389-97. doi: 10.1515/bmt-2012-0148. Review.

PMID:
24101369
44.

In vivo degradation of magnesium alloy LA63 scaffolds for temporary stabilization of biological myocardial grafts in a swine model.

Schilling T, Brandes G, Tudorache I, Cebotari S, Hilfiker A, Meyer T, Biskup C, Bauer M, Waldmann KH, Bach FW, Haverich A, Hassel T.

Biomed Tech (Berl). 2013 Oct;58(5):407-16. doi: 10.1515/bmt-2012-0047.

PMID:
23989110
45.

Cardiovascular disorders in pregnancy: diagnosis and management.

Westhoff-Bleck M, Podewski E, Hilfiker A, Hilfiker-Kleiner D.

Best Pract Res Clin Obstet Gynaecol. 2013 Dec;27(6):821-34. doi: 10.1016/j.bpobgyn.2013.07.001. Epub 2013 Aug 8. Review.

PMID:
23932772
46.

Collagen-cellulose composite thin films that mimic soft-tissue and allow stem-cell orientation.

Steele TW, Huang CL, Nguyen E, Sarig U, Kumar S, Widjaja E, Loo JS, Machluf M, Boey F, Vukadinovic Z, Hilfiker A, Venkatraman SS.

J Mater Sci Mater Med. 2013 Aug;24(8):2013-27. doi: 10.1007/s10856-013-4940-3. Epub 2013 May 14.

PMID:
23670603
47.

Orthotopic replacement of aortic heart valves with tissue-engineered grafts.

Tudorache I, Calistru A, Baraki H, Meyer T, Höffler K, Sarikouch S, Bara C, Görler A, Hartung D, Hilfiker A, Haverich A, Cebotari S.

Tissue Eng Part A. 2013 Aug;19(15-16):1686-94. doi: 10.1089/ten.TEA.2012.0074. Epub 2013 Apr 26.

48.

Development of implantable autologous small-calibre vascular grafts from peripheral blood samples.

Aper T, Teebken OE, Krüger A, Heisterkamp A, Hilfiker A, Haverich A.

Zentralbl Chir. 2013 Apr;138(2):173-9. doi: 10.1055/s-0032-1315112. Epub 2013 Jan 22.

PMID:
23341132
49.

Small intestinal submucosa segments as matrix for tissue engineering: review.

Andrée B, Bär A, Haverich A, Hilfiker A.

Tissue Eng Part B Rev. 2013 Aug;19(4):279-91. doi: 10.1089/ten.TEB.2012.0583. Epub 2013 Jan 14. Review.

PMID:
23216258
50.

Tracheal cartilage - evaluating the potential of a novel biomaterial for reconstructive cardiovascular procedures.

Minol JP, Baraki H, Akhyari P, Bagaev E, Suprunov M, Brandes G, Bara C, Hort W, Hurschler C, Sigler M, Haverich A, Hilfiker A, Lichtenberg A.

J Tissue Eng Regen Med. 2014 Nov;8(11):850-61. doi: 10.1002/term.1585. Epub 2012 Jul 27.

PMID:
22837178

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