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Items: 9


Gene editing restores dystrophin expression in a canine model of Duchenne muscular dystrophy.

Amoasii L, Hildyard JCW, Li H, Sanchez-Ortiz E, Mireault A, Caballero D, Harron R, Stathopoulou TR, Massey C, Shelton JM, Bassel-Duby R, Piercy RJ, Olson EN.

Science. 2018 Oct 5;362(6410):86-91. doi: 10.1126/science.aau1549. Epub 2018 Aug 30.


Determination of qPCR Reference Genes Suitable for Normalizing Gene Expression in a Canine Model of Duchenne Muscular Dystrophy.

Hildyard JCW, Taylor-Brown F, Massey C, Wells DJ, Piercy RJ.

J Neuromuscul Dis. 2018;5(2):177-191. doi: 10.3233/JND-170267.


Focus on the Role of D-serine and D-amino Acid Oxidase in Amyotrophic Lateral Sclerosis/Motor Neuron Disease (ALS).

Kondori NR, Paul P, Robbins JP, Liu K, Hildyard JCW, Wells DJ, de Belleroche JS.

Front Mol Biosci. 2018 Feb 13;5:8. doi: 10.3389/fmolb.2018.00008. eCollection 2018. Review.


Characterisation of the pathogenic effects of the in vivo expression of an ALS-linked mutation in D-amino acid oxidase: Phenotype and loss of spinal cord motor neurons.

Kondori NR, Paul P, Robbins JP, Liu K, Hildyard JCW, Wells DJ, de Belleroche JS.

PLoS One. 2017 Dec 1;12(12):e0188912. doi: 10.1371/journal.pone.0188912. eCollection 2017.


Investigating Synthetic Oligonucleotide Targeting of Mir31 in Duchenne Muscular Dystrophy.

Hildyard JC, Wells DJ.

PLoS Curr. 2016 Jun 16;8. pii: doi: 10.1371/


Transgenic Rescue of the LARGEmyd Mouse: A LARGE Therapeutic Window?

Hildyard JC, Lacey E, Booler H, Hopkinson M, Wells DJ, Brown SC.

PLoS One. 2016 Jul 28;11(7):e0159853. doi: 10.1371/journal.pone.0159853. eCollection 2016.


Identification and validation of quantitative PCR reference genes suitable for normalizing expression in normal and dystrophic cell culture models of myogenesis.

Hildyard JC, Wells DJ.

PLoS Curr. 2014 Mar 6;6. pii: doi: 10.1371/


Identification and characterisation of a new class of highly specific and potent inhibitors of the mitochondrial pyruvate carrier.

Hildyard JC, Ammälä C, Dukes ID, Thomson SA, Halestrap AP.

Biochim Biophys Acta. 2005 Apr-May;1707(2-3):221-30. Epub 2004 Dec 30.


Identification of the mitochondrial pyruvate carrier in Saccharomyces cerevisiae.

Hildyard JC, Halestrap AP.

Biochem J. 2003 Sep 15;374(Pt 3):607-11.

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