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Items: 1 to 50 of 63

1.

The N54-αs Mutant Has Decreased Affinity for βγ and Suggests a Mechanism for Coupling Heterotrimeric G Protein Nucleotide Exchange with Subunit Dissociation.

Cleator JH, Wells CA, Dingus J, Kurtz DT, Hildebrandt JD.

J Pharmacol Exp Ther. 2018 May;365(2):219-225. doi: 10.1124/jpet.117.245779. Epub 2018 Feb 28.

PMID:
29491039
2.

Synthesis and assembly of G protein βγ dimers: comparison of in vitro and in vivo studies.

Dingus J, Hildebrandt JD.

Subcell Biochem. 2012;63:155-80. doi: 10.1007/978-94-007-4765-4_9. Review.

PMID:
23161138
3.

Aquaporin 0-calmodulin interaction and the effect of aquaporin 0 phosphorylation.

Rose KM, Wang Z, Magrath GN, Hazard ES, Hildebrandt JD, Schey KL.

Biochemistry. 2008 Jan 8;47(1):339-47. Epub 2007 Dec 15.

PMID:
18081321
5.

Role of the chaperonin CCT/TRiC complex in G protein betagamma-dimer assembly.

Wells CA, Dingus J, Hildebrandt JD.

J Biol Chem. 2006 Jul 21;281(29):20221-32. Epub 2006 May 15.

6.

Bring your own G protein.

Hildebrandt JD.

Mol Pharmacol. 2006 Apr;69(4):1079-82. Epub 2006 Jan 25.

7.

Proteomic analysis of bovine brain G protein gamma subunit processing heterogeneity.

Cook LA, Schey KL, Wilcox MD, Dingus J, Ettling R, Nelson T, Knapp DR, Hildebrandt JD.

Mol Cell Proteomics. 2006 Apr;5(4):671-85. Epub 2005 Dec 6.

8.

G Protein betagamma dimer formation: Gbeta and Ggamma differentially determine efficiency of in vitro dimer formation.

Dingus J, Wells CA, Campbell L, Cleator JH, Robinson K, Hildebrandt JD.

Biochemistry. 2005 Sep 6;44(35):11882-90.

PMID:
16128590
9.
10.
12.

Gamma 2 subunit of G protein heterotrimer is an N-end rule ubiquitylation substrate.

Hamilton MH, Cook LA, McRackan TR, Schey KL, Hildebrandt JD.

Proc Natl Acad Sci U S A. 2003 Apr 29;100(9):5081-6. Epub 2003 Apr 16.

13.

Pertussis toxin-insensitive activation of the heterotrimeric G-proteins Gi/Go by the NG108-15 G-protein activator.

Ribas C, Takesono A, Sato M, Hildebrandt JD, Lanier SM.

J Biol Chem. 2002 Dec 27;277(52):50223-5. Epub 2002 Nov 7.

14.

Structural characterization of intact G protein gamma subunits by mass spectrometry.

Schey KL, Busman M, Cook LA, Hamm HE, Hildebrandt JD.

Methods Enzymol. 2002;344:586-97. No abstract available.

PMID:
11771413
15.

Characterization of deamidated G protein subunits.

McIntire WE, Schey KL, Knapp DR, Dingus J, Hildebrandt JD.

Methods Enzymol. 2002;344:481-505. No abstract available.

PMID:
11771405
16.

Separation and analysis of G protein gamma subunits.

Cook LA, Wilcox MD, Dingus J, Schey KL, Hildebrandt JD.

Methods Enzymol. 2002;344:209-33. No abstract available.

PMID:
11771385
17.

Analysis of signal transfer from receptor to Go/Gi in different membrane environments and receptor-independent activators of brain G protein.

Ribas C, Sato M, Hildebrandt JD, Lanier SM.

Methods Enzymol. 2002;344:140-52. No abstract available.

PMID:
11771378
18.

Identification of a region in G protein gamma subunits conserved across species but hypervariable among subunit isoforms.

Cook LA, Schey KL, Cleator JH, Wilcox MD, Dingus J, Hildebrandt JD.

Protein Sci. 2001 Dec;10(12):2548-55.

19.

Identification of Gbetagamma binding sites in the third intracellular loop of the M(3)-muscarinic receptor and their role in receptor regulation.

Wu G, Bogatkevich GS, Mukhin YV, Benovic JL, Hildebrandt JD, Lanier SM.

J Biol Chem. 2000 Mar 24;275(12):9026-34.

21.
23.

A major G protein alpha O isoform in bovine brain is deamidated at Asn346 and Asn347, residues involved in receptor coupling.

McIntire WE, Schey KL, Knapp DR, Hildebrandt JD.

Biochemistry. 1998 Oct 20;37(42):14651-8.

PMID:
9778339
24.

Heterogeneous processing of a G protein gamma subunit at a site critical for protein and membrane interactions.

Cook LA, Schey KL, Wilcox MD, Dingus J, Hildebrandt JD.

Biochemistry. 1998 Sep 1;37(35):12280-6.

PMID:
9724542
25.

Receptor docking sites for G-protein betagamma subunits. Implications for signal regulation.

Wu G, Benovic JL, Hildebrandt JD, Lanier SM.

J Biol Chem. 1998 Mar 27;273(13):7197-200.

26.

Role of subunit diversity in signaling by heterotrimeric G proteins.

Hildebrandt JD.

Biochem Pharmacol. 1997 Aug 1;54(3):325-39. Review.

PMID:
9278091
27.

A surface on the G protein beta-subunit involved in interactions with adenylyl cyclases.

Chen Y, Weng G, Li J, Harry A, Pieroni J, Dingus J, Hildebrandt JD, Guarnieri F, Weinstein H, Iyengar R.

Proc Natl Acad Sci U S A. 1997 Mar 18;94(6):2711-4.

28.

Characterization of a G-protein activator in the neuroblastoma-glioma cell hybrid NG108-15.

Sato M, Ribas C, Hildebrandt JD, Lanier SM.

J Biol Chem. 1996 Nov 22;271(47):30052-60.

29.
30.

Determination of the complete covalent structure of the gamma 2 subunit of bovine brain G proteins by mass spectrometry.

Wilcox MD, Schey KL, Busman M, Hildebrandt JD.

Biochem Biophys Res Commun. 1995 Jul 17;212(2):367-74.

PMID:
7626050
31.

Factors determining specificity of signal transduction by G-protein-coupled receptors. Regulation of signal transfer from receptor to G-protein.

Sato M, Kataoka R, Dingus J, Wilcox M, Hildebrandt JD, Lanier SM.

J Biol Chem. 1995 Jun 23;270(25):15269-76.

32.

Gi is involved in ethanol inhibition of L-type calcium channels in undifferentiated but not differentiated PC-12 cells.

Mullikin-Kilpatrick D, Mehta ND, Hildebrandt JD, Treistman SN.

Mol Pharmacol. 1995 May;47(5):997-1005.

PMID:
7746286
33.

Bovine brain GO isoforms have distinct gamma subunit compositions.

Wilcox MD, Dingus J, Balcueva EA, McIntire WE, Mehta ND, Schey KL, Robishaw JD, Hildebrandt JD.

J Biol Chem. 1995 Mar 3;270(9):4189-92.

34.

Analysis of G protein gamma subunit heterogeneity using mass spectrometry.

Wilcox MD, Schey KL, Dingus J, Mehta ND, Tatum BS, Halushka M, Finch JW, Hildebrandt JD.

J Biol Chem. 1994 Apr 29;269(17):12508-13.

35.

The effect of pertussis toxin on the growth of vascular smooth muscle cells stimulated by serum or platelet-derived growth factor.

Zhang LM, Newman WH, Castresana MR, Hildebrandt JD.

Endocrinology. 1994 Mar;134(3):1297-304.

PMID:
8119169
36.

Synthesis and use of biotinylated beta gamma complexes prepared from bovine brain G proteins.

Dingus J, Wilcox MD, Kohnken R, Hildebrandt JD.

Methods Enzymol. 1994;237:457-71. No abstract available.

PMID:
7935020
37.

A mutation in the putative Mg(2+)-binding site of Gs alpha prevents its activation by receptors.

Hildebrandt JD, Day R, Farnsworth CL, Feig LA.

Mol Cell Biol. 1991 Oct;11(10):4830-8.

38.

Effect of ras-gene transformation on the inhibition of NIH3T3 cell growth by pertussis toxin.

Hildebrandt JD, Lederman L, Steffen DL.

Mol Endocrinol. 1991 Aug;5(8):1101-8.

PMID:
1944306
39.
40.

Differential regulation of G protein subunit expression in mouse oocytes, eggs, and early embryos.

Allworth AE, Hildebrandt JD, Ziomek CA.

Dev Biol. 1990 Nov;142(1):129-37.

PMID:
2121565
41.
42.

Distinct guanine nucleotide binding and release properties of the three Gi proteins.

Carty DJ, Padrell E, Codina J, Birnbaumer L, Hildebrandt JD, Iyengar R.

J Biol Chem. 1990 Apr 15;265(11):6268-73.

43.

G protein subunit interactions. Studies with biotinylated G protein subunits.

Kohnken RE, Hildebrandt JD.

J Biol Chem. 1989 Dec 5;264(34):20688-96.

44.

Pertussis toxin alters the growth characteristics of Swiss 3T3 cells.

Hildebrandt JD, Stolzenberg E, Graves J.

FEBS Lett. 1986 Jul 14;203(1):87-90.

46.

The membrane-bound spermatozoal adenylyl cyclase system does not share coupling characteristics with somatic cell adenylyl cyclases.

Hildebrandt JD, Codina J, Tash JS, Kirchick HJ, Lipschultz L, Sekura RD, Birnbaumer L.

Endocrinology. 1985 Apr;116(4):1357-66.

PMID:
3918851
47.

Purification of Ns and Ni, the coupling proteins of hormone-sensitive adenylyl cyclases without intervention of activating regulatory ligands.

Codina J, Rosenthal W, Hildebrandt JD, Birnbaumer L, Sekura RD.

Methods Enzymol. 1985;109:446-65. No abstract available.

PMID:
3921803
48.

Properties of human erythrocyte Ns and Ni, the regulatory components of adenylate cyclase, as purified without regulatory ligands.

Hildebrandt JD, Codina J, Rosenthal W, Sunyer T, Iyengar R, Birnbaumer L.

Adv Cyclic Nucleotide Protein Phosphorylation Res. 1985;19:87-101. No abstract available.

PMID:
3159187
49.

Regulation of hormone receptors and adenylyl cyclases by guanine nucleotide binding N proteins.

Birnbaumer L, Codina J, Mattera R, Cerione RA, Hildebrandt JD, Sunyer T, Rojas FJ, Caron MG, Lefkowitz RJ, Iyengar R.

Recent Prog Horm Res. 1985;41:41-99. Review. No abstract available.

PMID:
2996090
50.

ADP-ribosylation of membrane components by pertussis and cholera toxin.

Ribeiro-Neto FA, Mattera R, Hildebrandt JD, Codina J, Field JB, Birnbaumer L, Sekura RD.

Methods Enzymol. 1985;109:566-72. No abstract available.

PMID:
2859516

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