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Lymphopenia at diagnosis is highly prevalent in myelodysplastic syndromes and has an independent negative prognostic value in IPSS-R-low-risk patients.

Silzle T, Blum S, Schuler E, Kaivers J, Rudelius M, Hildebrandt B, Gattermann N, Haas R, Germing U.

Blood Cancer J. 2019 Aug 9;9(8):63. doi: 10.1038/s41408-019-0223-7.


Comprehensive analysis of isolated der(1;7)(q10;p10) in a large international homogenous cohort of patients with myelodysplastic syndromes.

Ganster C, Müller-Thomas C, Haferlach C, Strupp C, Ogata K, Germing U, Hildebrandt B, Mallo M, Lübbert M, Müller C, Solé F, Götze KS, Vandenberghe P, Göhring G, Steinmetz T, Kröger N, Platzbecker U, Söling U, Raynaud S, Shirneshan K, Schanz J, Haase D.

Genes Chromosomes Cancer. 2019 Oct;58(10):689-697. doi: 10.1002/gcc.22760. Epub 2019 Apr 30.


Clonal architecture in patients with myelodysplastic syndromes and double or minor complex abnormalities: Detailed analysis of clonal composition, involved abnormalities, and prognostic significance.

Schanz J, Solé F, Mallo M, Luño E, Cervera J, Granada I, Hildebrandt B, Slovak ML, Ohyashiki K, Fonatsch C, Pfeilstöcker M, Nösslinger T, Valent P, Giagounidis A, Aul C, Lübbert M, Stauder R, Krieger O, Le Beau MM, Bennett JM, Greenberg P, Germing U, Haase D.

Genes Chromosomes Cancer. 2018 Nov;57(11):547-556. doi: 10.1002/gcc.22667. Epub 2018 Sep 24.


Long-term outcome of high risk patients with myelodysplastic syndromes or secondary acute myeloid leukemia receiving intensive chemotherapy.

Schuler E, Zadrozny N, Blum S, Schroeder T, Strupp C, Hildebrandt B, Kündgen A, Gattermann N, Aul C, Kondakci M, Kobbe G, Haas R, Germing U.

Ann Hematol. 2018 Dec;97(12):2325-2332. doi: 10.1007/s00277-018-3466-7. Epub 2018 Aug 4.


The IPSS-R has prognostic impact in untreated patients with MDS del(5q).

Kaivers J, Lauseker M, Hildebrandt B, Fenaux P, Pfeilstöcker M, Valent P, Platzbecker U, Latagliata R, Oliva EN, Xicoy B, Götze K, Ganster C, Haase D, Bug G, Kündgen A, Gattermann N, Haas R, Germing U.

Leuk Res. 2018 Sep;72:27-33. doi: 10.1016/j.leukres.2018.07.019. Epub 2018 Jul 23.


Exploring reward system responsivity in the nucleus accumbens across chronicity of binge eating in female rats.

Hildebrandt BA, Sinclair EB, Sisk CL, Klump KL.

Int J Eat Disord. 2018 Aug;51(8):989-993. doi: 10.1002/eat.22895. Epub 2018 Jul 29.


Efficacy of azacitidine is independent of molecular and clinical characteristics - an analysis of 128 patients with myelodysplastic syndromes or acute myeloid leukemia and a review of the literature.

Kuendgen A, Müller-Thomas C, Lauseker M, Haferlach T, Urbaniak P, Schroeder T, Brings C, Wulfert M, Meggendorfer M, Hildebrandt B, Betz B, Royer-Pokora B, Gattermann N, Haas R, Germing U, Götze KS.

Oncotarget. 2018 Jun 12;9(45):27882-27894. doi: 10.18632/oncotarget.25328. eCollection 2018 Jun 12. Review.


Wilms' Tumor 1 Gene Expression Using a Standardized European LeukemiaNet-Certified Assay Compared to Other Methods for Detection of Minimal Residual Disease in Myelodysplastic Syndrome and Acute Myelogenous Leukemia after Allogeneic Blood Stem Cell Transplantation.

Rautenberg C, Pechtel S, Hildebrandt B, Betz B, Dienst A, Nachtkamp K, Kondakci M, Geyh S, Wieczorek D, Haas R, Germing U, Kobbe G, Schroeder T.

Biol Blood Marrow Transplant. 2018 Nov;24(11):2337-2343. doi: 10.1016/j.bbmt.2018.05.011. Epub 2018 May 16.


Satiation deficits and binge eating: Probing differences between bulimia nervosa and purging disorder using an ad lib test meal.

Keel PK, Haedt-Matt AA, Hildebrandt B, Bodell LP, Wolfe BE, Jimerson DC.

Appetite. 2018 Aug 1;127:119-125. doi: 10.1016/j.appet.2018.04.009. Epub 2018 Apr 11.


Perinatal testosterone contributes to mid-to-post pubertal sex differences in risk for binge eating in male and female rats.

Culbert KM, Sinclair EB, Hildebrandt BA, Klump KL, Sisk CL.

J Abnorm Psychol. 2018 Feb;127(2):239-250. doi: 10.1037/abn0000334.


Disturbance of gut satiety peptide in purging disorder.

Keel PK, Eckel LA, Hildebrandt BA, Haedt-Matt AA, Appelbaum J, Jimerson DC.

Int J Eat Disord. 2018 Jan;51(1):53-61. doi: 10.1002/eat.22806. Epub 2017 Dec 8.


Myelodysplastic syndromes without peripheral monocytosis but with evidence of marrow monocytosis share clinical and molecular characteristics with CMML.

Schuler E, Frank F, Hildebrandt B, Betz B, Strupp C, Rudelius M, Aul C, Schroeder T, Gattermann N, Haas R, Germing U.

Leuk Res. 2018 Feb;65:1-4. doi: 10.1016/j.leukres.2017.12.002. Epub 2017 Dec 5.


Comparative performance analysis of human iPSC-derived and primary neural progenitor cells (NPC) grown as neurospheres in vitro.

Hofrichter M, Nimtz L, Tigges J, Kabiri Y, Schröter F, Royer-Pokora B, Hildebrandt B, Schmuck M, Epanchintsev A, Theiss S, Adjaye J, Egly JM, Krutmann J, Fritsche E.

Stem Cell Res. 2017 Dec;25:72-82. doi: 10.1016/j.scr.2017.10.013. Epub 2017 Oct 26.


Cytogenetic clonal evolution in myelodysplastic syndromes is associated with inferior prognosis.

Neukirchen J, Lauseker M, Hildebrandt B, Nolting AC, Kaivers J, Kobbe G, Gattermann N, Haas R, Germing U.

Cancer. 2017 Dec 1;123(23):4608-4616. doi: 10.1002/cncr.30917. Epub 2017 Jul 26.


Preliminary evidence of sex differences in behavioral and neural responses to palatable food reward in rats.

Sinclair EB, Hildebrandt BA, Culbert KM, Klump KL, Sisk CL.

Physiol Behav. 2017 Jul 1;176:165-173. doi: 10.1016/j.physbeh.2017.03.042. Epub 2017 Mar 30.


New proposals of the WHO working group (2016) for the diagnosis of myelodysplastic syndromes (MDS): Characteristics of refined MDS types.

Strupp C, Nachtkamp K, Hildebrandt B, Giagounidis A, Haas R, Gattermann N, Bennett JM, Aul C, Germing U.

Leuk Res. 2017 Jun;57:78-84. doi: 10.1016/j.leukres.2017.02.008. Epub 2017 Feb 27.


Resting heart rate is an independent predictor of death in patients with colorectal, pancreatic, and non-small cell lung cancer: results of a prospective cardiovascular long-term study.

Anker MS, Ebner N, Hildebrandt B, Springer J, Sinn M, Riess H, Anker SD, Landmesser U, Haverkamp W, von Haehling S.

Eur J Heart Fail. 2016 Dec;18(12):1524-1534. doi: 10.1002/ejhf.670.


Differential Effects of Estrogen and Progesterone on Genetic and Environmental Risk for Emotional Eating in Women.

Klump KL, O'Connor SM, Hildebrandt BA, Keel PK, Neale M, Sisk CL, Boker S, Burt SA.

Clin Psychol Sci. 2016 Sep;4(5):895-908. Epub 2016 Sep 25.


Causes of death in 2877 patients with myelodysplastic syndromes.

Nachtkamp K, Stark R, Strupp C, Kündgen A, Giagounidis A, Aul C, Hildebrandt B, Haas R, Gattermann N, Germing U.

Ann Hematol. 2016 May;95(6):937-44. doi: 10.1007/s00277-016-2649-3. Epub 2016 Mar 30.


Frequency of del(12p) is commonly underestimated in myelodysplastic syndromes: Results from a German diagnostic study in comparison with an international control group.

Braulke F, Müller-Thomas C, Götze K, Platzbecker U, Germing U, Hofmann WK, Giagounidis AA, Lübbert M, Greenberg PL, Bennett JM, Solé F, Slovak ML, Ohyashiki K, Le Beau MM, Tüchler H, Pfeilstöcker M, Hildebrandt B, Aul C, Stauder R, Valent P, Fonatsch C, Bacher U, Trümper L, Haase D, Schanz J.

Genes Chromosomes Cancer. 2015 Dec;54(12):809-17. doi: 10.1002/gcc.22292. Epub 2015 Sep 10.


Upfront FOLFOXIRI+bevacizumab followed by fluoropyrimidin and bevacizumab maintenance in patients with molecularly unselected metastatic colorectal cancer.

Stein A, Atanackovic D, Hildebrandt B, Stübs P, Brugger W, Hapke G, Steffens CC, Illerhaus G, Bluemner E, Stöhlmacher J, Bokemeyer C.

Br J Cancer. 2015 Sep 15;113(6):872-7. doi: 10.1038/bjc.2015.299. Epub 2015 Sep 3.


Changes in genetic risk for emotional eating across the menstrual cycle: a longitudinal study.

Klump KL, Hildebrandt BA, O'Connor SM, Keel PK, Neale M, Sisk CL, Boker S, Burt SA.

Psychol Med. 2015 Nov;45(15):3227-37. doi: 10.1017/S0033291715001221. Epub 2015 Jul 15.


Properties of soil pore space regulate pathways of plant residue decomposition and community structure of associated bacteria.

Negassa WC, Guber AK, Kravchenko AN, Marsh TL, Hildebrandt B, Rivers ML.

PLoS One. 2015 Apr 24;10(4):e0123999. doi: 10.1371/journal.pone.0123999. eCollection 2015.


Reply: Cardiovascular function and exercise capacity in patients with colorectal cancer: does anticancer therapy matter?

Cramer L, Hildebrandt B, Springer J, Riess H, Anker SD, von Haehling S.

J Am Coll Cardiol. 2015 Apr 7;65(13):1381-1382. doi: 10.1016/j.jacc.2014.12.055. No abstract available.


Structural chromosome abnormalities, increased DNA strand breaks and DNA strand break repair deficiency in dermal fibroblasts from old female human donors.

Kalfalah F, Seggewiß S, Walter R, Tigges J, Moreno-Villanueva M, Bürkle A, Ohse S, Busch H, Boerries M, Hildebrandt B, Royer-Pokora B, Boege F.

Aging (Albany NY). 2015 Feb;7(2):110-22.


Contribution of human papilloma virus to the incidence of squamous cell carcinoma of the head and neck in a European population with high smoking prevalence.

Tinhofer I, Jöhrens K, Keilholz U, Kaufmann A, Lehmann A, Weichert W, Stenzinger A, Stromberger C, Klinghammer K, Becker ET, Dommerich S, Stölzel K, Hofmann VM, Hildebrandt B, Moser L, Ervens J, Böttcher A, Albers A, Stabenow R, Reinecke A, Budach V, Hoffmeister B, Raguse JD.

Eur J Cancer. 2015 Mar;51(4):514-21. doi: 10.1016/j.ejca.2014.12.018. Epub 2015 Jan 23.


Refined medullary blast and white blood cell count based classification of chronic myelomonocytic leukemias.

Schuler E, Schroeder M, Neukirchen J, Strupp C, Xicoy B, Kündgen A, Hildebrandt B, Haas R, Gattermann N, Germing U.

Leuk Res. 2014 Dec;38(12):1413-9. doi: 10.1016/j.leukres.2014.09.003. Epub 2014 Sep 17.


Validation of cytogenetic risk groups according to International Prognostic Scoring Systems by peripheral blood CD34+FISH: results from a German diagnostic study in comparison with an international control group.

Braulke F, Platzbecker U, Müller-Thomas C, Götze K, Germing U, Brümmendorf TH, Nolte F, Hofmann WK, Giagounidis AA, Lübbert M, Greenberg PL, Bennett JM, Solé F, Mallo M, Slovak ML, Ohyashiki K, Le Beau MM, Tüchler H, Pfeilstöcker M, Nösslinger T, Hildebrandt B, Shirneshan K, Aul C, Stauder R, Sperr WR, Valent P, Fonatsch C, Trümper L, Haase D, Schanz J.

Haematologica. 2015 Feb;100(2):205-13. doi: 10.3324/haematol.2014.110452. Epub 2014 Oct 24.


Ovarian Hormone Influences on Dysregulated Eating: A Comparison of Associations in Women with versus without Binge Episodes.

Klump KL, Racine SE, Hildebrandt B, Burt SA, Neale M, Sisk CL, Boker S, Keel PK.

Clin Psychol Sci. 2014 Sep 1;2(4):545-559.


Cardiovascular function and predictors of exercise capacity in patients with colorectal cancer.

Cramer L, Hildebrandt B, Kung T, Wichmann K, Springer J, Doehner W, Sandek A, Valentova M, Stojakovic T, Scharnagl H, Riess H, Anker SD, von Haehling S.

J Am Coll Cardiol. 2014 Sep 30;64(13):1310-9. doi: 10.1016/j.jacc.2014.07.948.


Lymph node count and prognosis in colorectal cancer: the influence of examination quality.

Bläker H, Hildebrandt B, Riess H, von Winterfeld M, Ingold-Heppner B, Roth W, Kloor M, Schirmacher P, Dietel M, Tao S, Jansen L, Chang-Claude J, Ulrich A, Brenner H, Hoffmeister M.

Int J Cancer. 2015 Apr 15;136(8):1957-66. doi: 10.1002/ijc.29221. Epub 2014 Sep 24.


The effects of ovarian hormones and emotional eating on changes in weight preoccupation across the menstrual cycle.

Hildebrandt BA, Racine SE, Keel PK, Burt SA, Neale M, Boker S, Sisk CL, Klump KL.

Int J Eat Disord. 2015 Jul;48(5):477-86. doi: 10.1002/eat.22326. Epub 2014 Jun 26.


Differential strain vulnerability to binge eating behaviors in rats.

Hildebrandt BA, Klump KL, Racine SE, Sisk CL.

Physiol Behav. 2014 Mar 29;127:81-6. doi: 10.1016/j.physbeh.2014.01.012. Epub 2014 Jan 28.


The myelodysplastic syndrome-comorbidity index provides additional prognostic information on patients stratified according to the revised international prognostic scoring system.

Zipperer E, Tanha N, Strupp C, Kündgen A, Nachtkamp K, Neukirchen J, Hildebrandt B, Haas R, Gattermann N, Germing U.

Haematologica. 2014 Mar;99(3):e31-2. doi: 10.3324/haematol.2013.101055. Epub 2014 Jan 24. No abstract available.


Unresectable colorectal liver metastases: percutaneous ablation using CT-guided high-dose-rate brachytherapy (CT-HDBRT).

Collettini F, Lutter A, Schnapauff D, Hildebrandt B, Puhl G, Denecke T, Wust P, Gebauer B.

Rofo. 2014 Jun;186(6):606-12. doi: 10.1055/s-0033-1355887. Epub 2014 Jan 9.


Validation of the revised international prognostic scoring system (IPSS-R) in patients with myelodysplastic syndrome: a multicenter study.

Neukirchen J, Lauseker M, Blum S, Giagounidis A, Lübbert M, Martino S, Siragusa S, Schlenk RF, Platzbecker U, Hofmann WK, Götze K, Palumbo GA, Magrin S, Kündgen A, Aul C, Hildebrandt B, Hasford J, Kobbe G, Haas R, Germing U.

Leuk Res. 2014 Jan;38(1):57-64. doi: 10.1016/j.leukres.2013.10.013. Epub 2013 Oct 26.


Constitutive expression of the K-domain of a Vaccinium corymbosum SOC1-like (VcSOC1-K) MADS-box gene is sufficient to promote flowering in tobacco.

Song GQ, Walworth A, Zhao D, Hildebrandt B, Leasia M.

Plant Cell Rep. 2013 Nov;32(11):1819-26. doi: 10.1007/s00299-013-1495-1. Epub 2013 Aug 21.


Interventionally implanted port catheter systems for hepatic arterial infusion of chemotherapy in patients with primary liver cancer: a phase II-study (NCT00356161).

Sinn M, Nicolaou A, Ricke J, Podrabsky P, Seehofer D, Gebauer B, Pech M, Neuhaus P, Dörken B, Riess H, Hildebrandt B.

BMC Gastroenterol. 2013 Aug 9;13:125. doi: 10.1186/1471-230X-13-125.


Langevin dynamics simulation of DNA ejection from a phage.

Mahalik JP, Hildebrandt B, Muthukumar M.

J Biol Phys. 2013 Mar;39(2):229-45. doi: 10.1007/s10867-013-9316-x. Epub 2013 Apr 23.


Monosomal karyotype in MDS: explaining the poor prognosis?

Schanz J, Tüchler H, Solé F, Mallo M, Luño E, Cervera J, Grau J, Hildebrandt B, Slovak ML, Ohyashiki K, Steidl C, Fonatsch C, Pfeilstöcker M, Nösslinger T, Valent P, Giagounidis A, Aul C, Lübbert M, Stauder R, Krieger O, Le Beau MM, Bennett JM, Greenberg P, Germing U, Haase D.

Leukemia. 2013 Oct;27(10):1988-95. doi: 10.1038/leu.2013.187. Epub 2013 Jun 21.


Non-invasive assessment of cardiac hemodynamics in patients with advanced cancer and with chronic heart failure: a pilot feasibility study.

von Haehling S, Lainscak M, Kung T, Cramer L, Fülster S, Pelzer U, Hildebrandt B, Sandek A, Schefold JC, Rauchhaus M, Doehner W, Anker SD.

Arch Med Sci. 2013 Apr 20;9(2):261-7. doi: 10.5114/aoms.2013.34574. Epub 2013 Apr 22.


Sex differences in binge eating patterns in male and female adult rats.

Klump KL, Racine S, Hildebrandt B, Sisk CL.

Int J Eat Disord. 2013 Nov;46(7):729-36. doi: 10.1002/eat.22139. Epub 2013 Apr 29.


Hepatic arterial infusion with oxaliplatin and 5-FU/folinic acid for advanced biliary tract cancer: a phase II study.

Sinn M, Nicolaou A, Gebauer B, Podrabsky P, Seehofer D, Ricke J, Dörken B, Riess H, Hildebrandt B.

Dig Dis Sci. 2013 Aug;58(8):2399-405. doi: 10.1007/s10620-013-2624-y. Epub 2013 Mar 24.


Development and validation of a prognostic scoring system for patients with chronic myelomonocytic leukemia.

Such E, Germing U, Malcovati L, Cervera J, Kuendgen A, Della Porta MG, Nomdedeu B, Arenillas L, Luño E, Xicoy B, Amigo ML, Valcarcel D, Nachtkamp K, Ambaglio I, Hildebrandt B, Lorenzo I, Cazzola M, Sanz G.

Blood. 2013 Apr 11;121(15):3005-15. doi: 10.1182/blood-2012-08-452938. Epub 2013 Jan 31.


Validation and proposals for a refinement of the WHO 2008 classification of myelodysplastic syndromes without excess of blasts.

Maassen A, Strupp C, Giagounidis A, Kuendgen A, Nachtkamp K, Hildebrandt B, Gattermann N, Aul C, Haas R, Germing U.

Leuk Res. 2013 Jan;37(1):64-70. doi: 10.1016/j.leukres.2012.09.021. Epub 2012 Oct 31.


Griseofulvin inhibits the growth of adrenocortical cancer cells in vitro.

Bramann EL, Willenberg HS, Hildebrandt B, Müller-Mattheis V, Schott M, Scherbaum WA, Haase M.

Horm Metab Res. 2013 Apr;45(4):297-300. doi: 10.1055/s-0032-1327642. Epub 2012 Oct 30.


Treatment with bevacizumab and FOLFOXIRI in patients with advanced colorectal cancer: presentation of two novel trials (CHARTA and PERIMAX) and review of the literature.

Stein A, Glockzin G, Wienke A, Arnold D, Edelmann T, Hildebrandt B, Hollerbach S, Illerhaus G, Königsrainer A, Richter M, Schlitt HJ, Schmoll HJ.

BMC Cancer. 2012 Aug 16;12:356. doi: 10.1186/1471-2407-12-356. Review.


Treatment of poor-risk myelodysplastic syndromes and acute myeloid leukemia with a combination of 5-azacytidine and valproic acid.

Kuendgen A, Bug G, Ottmann OG, Haase D, Schanz J, Hildebrandt B, Nachtkamp K, Neukirchen J, Dienst A, Haas R, Germing U, Gattermann N.

Clin Epigenetics. 2011 Aug;2(2):389-99. doi: 10.1007/s13148-011-0031-9. Epub 2011 Apr 8.


Will a peripheral blood (PB) sample yield the same diagnostic and prognostic cytogenetic data as the concomitant bone marrow (BM) in myelodysplasia?

Cherry AM, Slovak ML, Campbell LJ, Chun K, Eclache V, Haase D, Haferlach C, Hildebrandt B, Iqbal AM, Jhanwar SC, Ohyashiki K, Sole F, Vandenberghe P, VanDyke DL, Zhang Y, Dewald GW.

Leuk Res. 2012 Jul;36(7):832-40. doi: 10.1016/j.leukres.2012.03.013. Epub 2012 Apr 25.


Expanding the chemistry of cationic N-heterocyclic carbenes: alternative synthesis, reactivity, and coordination chemistry.

Hildebrandt B, Raub S, Frank W, Ganter C.

Chemistry. 2012 May 21;18(21):6670-8. doi: 10.1002/chem.201103707. Epub 2012 Apr 4.


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