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Gait analysis and muscle weight analysis after lower extremity fractures in a small animal model.

Hofman M, Kolejewska A, Greven J, Andruszkow H, Kobbe P, Tolba R, Hildebrand F, Poeze M.

Gait Posture. 2020 Feb 6;77:207-213. doi: 10.1016/j.gaitpost.2020.01.022. [Epub ahead of print]


Disentangling the impact of environmental and phylogenetic constraints on prokaryotic within-species diversity.

Maistrenko OM, Mende DR, Luetge M, Hildebrand F, Schmidt TSB, Li SS, Rodrigues JFM, von Mering C, Pedro Coelho L, Huerta-Cepas J, Sunagawa S, Bork P.

ISME J. 2020 Feb 11. doi: 10.1038/s41396-020-0600-z. [Epub ahead of print]


[Posttraumatic deformity of the thoracolumbar spine].

Pishnamaz M, Scholz M, Trobisch PD, Lichte P, Herren C, Hildebrand F, Kobbe P.

Unfallchirurg. 2020 Feb;123(2):143-154. doi: 10.1007/s00113-019-00764-8. German.


Trauma Severity and Its Impact on Local Inflammation in Extremity Injury-Insights From a Combined Trauma Model in Pigs.

Horst K, Greven J, Lüken H, Zhi Q, Pfeifer R, Simon TP, Relja B, Marzi I, Pape HC, Hildebrand F.

Front Immunol. 2020 Jan 9;10:3028. doi: 10.3389/fimmu.2019.03028. eCollection 2019.


[Combined dorsoventral corrective spondylodesis in prone position : Treatment of posttraumatic kyphosis of the thoracolumbar junction].

Kobbe P, Scholz M, Trobisch PD, Lichte P, Herren C, Hildebrand F, Pishnamaz M.

Unfallchirurg. 2020 Feb;123(2):155-161. doi: 10.1007/s00113-019-00759-5. Review. German. No abstract available.


The impact of intramedullary nailing on the characteristics of the pulmonary neutrophil pool in rodents.

Teuben MPJ, Hofman M, Shehu A, Greven J, Qiao Z, Jensen KO, Hildebrand F, Pfeifer R, Pape HC.

Int Orthop. 2020 Mar;44(3):595-602. doi: 10.1007/s00264-019-04419-6. Epub 2020 Jan 3.


Non-invasive measurement of muscle compartment elasticity in lower limbs to determine acute compartment syndrome: Clinical results with pressure related ultrasound.

Sellei RM, Wollnitz J, Reinhardt N, de la Fuente M, Radermacher K, Weber C, Kobbe P, Hildebrand F.

Injury. 2020 Feb;51(2):301-306. doi: 10.1016/j.injury.2019.11.027. Epub 2019 Nov 21.


Club cell protein 16 in sera from trauma patients modulates neutrophil migration and functionality via CXCR1 and CXCR2.

Xu B, Janicova A, Vollrath JT, Störmann P, Martin L, Marzi I, Wutzler S, Hildebrand F, Ehnert S, Relja B.

Mol Med. 2019 Oct 30;25(1):45. doi: 10.1186/s10020-019-0115-0.


[Traumatic periprosthetic fractures in patients with total hip replacement].

Lichte P, Kobbe P, Pishnamaz M, Hildebrand F.

Unfallchirurg. 2019 Nov;122(11):885-900. doi: 10.1007/s00113-019-00727-z. German.


Endogenous Uteroglobin as Intrinsic Anti-inflammatory Signal Modulates Monocyte and Macrophage Subsets Distribution Upon Sepsis Induced Lung Injury.

Janicova A, Becker N, Xu B, Wutzler S, Vollrath JT, Hildebrand F, Ehnert S, Marzi I, Störmann P, Relja B.

Front Immunol. 2019 Oct 1;10:2276. doi: 10.3389/fimmu.2019.02276. eCollection 2019.


Review of Animal Models of Comorbidities in Fracture-Healing Research.

Haffner-Luntzer M, Hankenson KD, Ignatius A, Pfeifer R, Khader BA, Hildebrand F, van Griensven M, Pape HC, Lehmicke M.

J Orthop Res. 2019 Dec;37(12):2491-2498. doi: 10.1002/jor.24454. Epub 2019 Sep 3. Review.


A nationwide fluidics biobank of polytraumatized patients: implemented by the Network "Trauma Research" (NTF) as an expansion to the TraumaRegister DGU® of the German Trauma Society (DGU).

Relja B, Huber-Lang M, van Griensven M, Hildebrand F, Maegele M, Nienaber U, Brucker DP, Sturm R, Marzi I.

Eur J Trauma Emerg Surg. 2019 Jul 19. doi: 10.1007/s00068-019-01193-3. [Epub ahead of print] Review.


Biomechanical in vitro test of a novel dynamic spinal stabilisation system incorporating polycarbonate urethane material under physiological conditions.

Beckmann A, Nicolini LF, Grevenstein D, Backes H, Oikonomidis S, Sobottke R, Kobbe P, Hildebrand F, Stoffel M, Markert B, Siewe J, Herren C.

J Biomech Eng. 2019 Jul 17. doi: 10.1115/1.4044242. [Epub ahead of print]


Cardiac Glucose and Fatty Acid Transport After Experimental Mono- and Polytrauma.

Lackner I, Weber B, Knecht D, Horst K, Relja B, Gebhard F, Pape HC, Huber-Lang M, Hildebrand F, Kalbitz M; TREAT research group.

Shock. 2019 Jul 15. doi: 10.1097/SHK.0000000000001400. [Epub ahead of print]


Effect of neurokinin-1-receptor blockage on fracture healing in rats.

Hofman M, Rabenschlag F, Andruszkow H, Andruszkow J, Möckel D, Lammers T, Kolejewska A, Kobbe P, Greven J, Teuben MPJ, Poeze M, Hildebrand F.

Sci Rep. 2019 Jul 5;9(1):9744. doi: 10.1038/s41598-019-46278-6.


Incidence of post-traumatic pneumonia in poly-traumatized patients: identifying the role of traumatic brain injury and chest trauma.

Hofman M, Andruszkow H, Kobbe P, Poeze M, Hildebrand F.

Eur J Trauma Emerg Surg. 2019 Jul 3. doi: 10.1007/s00068-019-01179-1. [Epub ahead of print]


Age-Related Changes of Sprint Kinematics.

Dahl J, Degens H, Hildebrand F, Ganse B.

Front Physiol. 2019 Jun 12;10:613. doi: 10.3389/fphys.2019.00613. eCollection 2019.


Role of Nrf2 in Fracture Healing: Clinical Aspects of Oxidative Stress.

Kubo Y, Wruck CJ, Fragoulis A, Drescher W, Pape HC, Lichte P, Fischer H, Tohidnezhad M, Hildebrand F, Pufe T, Jahr H.

Calcif Tissue Int. 2019 Oct;105(4):341-352. doi: 10.1007/s00223-019-00576-3. Epub 2019 Jun 24. Review.


Early Local Inhibition of Club Cell Protein 16 Following Chest Trauma Reduces Late Sepsis-Induced Acute Lung Injury.

Störmann P, Becker N, Vollrath JT, Köhler K, Janicova A, Wutzler S, Hildebrand F, Marzi I, Relja B.

J Clin Med. 2019 Jun 22;8(6). pii: E896. doi: 10.3390/jcm8060896.


Influence of additional cement augmentation on endplate stability in circumferential stabilisation of osteoporotic spine fractures.

Herren C, Quast K, Prescher A, Fischer H, Thüring J, Siewe J, Hildebrand F, Greven J, Kobbe P, Pishnamaz M.

Clin Biomech (Bristol, Avon). 2019 Aug;68:163-168. doi: 10.1016/j.clinbiomech.2019.06.008. Epub 2019 Jun 11.


Towards standardisation of naming novel prokaryotic taxa in the age of high-throughput microbiology.

Hildebrand F, Pallen MJ, Bork P.

Gut. 2019 Jun 15. pii: gutjnl-2019-319045. doi: 10.1136/gutjnl-2019-319045. [Epub ahead of print] No abstract available.


Predictors for Pediatric Blunt Cerebrovascular Injury (BCVI): An International Multicenter Analysis.

Weber CD, Lefering R, Weber MS, Bier G, Knobe M, Pishnamaz M, Kobbe P, Hildebrand F; TraumaRegister DGU.

World J Surg. 2019 Sep;43(9):2337-2347. doi: 10.1007/s00268-019-05041-8.


The Impact of Plasma-Derived Microvesicles From a Femoral Fracture Animal Model on Osteoblast Function.

Qiao Z, Wang W, Luo P, Hofman M, Horst K, Müller-Newen G, Greven J, Hildebrand F.

Shock. 2020 Jan;53(1):78-87. doi: 10.1097/SHK.0000000000001336.


Ice-Age Climate Adaptations Trap the Alpine Marmot in a State of Low Genetic Diversity.

Gossmann TI, Shanmugasundram A, Börno S, Duvaux L, Lemaire C, Kuhl H, Klages S, Roberts LD, Schade S, Gostner JM, Hildebrand F, Vowinckel J, Bichet C, Mülleder M, Calvani E, Zelezniak A, Griffin JL, Bork P, Allaine D, Cohas A, Welch JJ, Timmermann B, Ralser M.

Curr Biol. 2019 May 20;29(10):1712-1720.e7. doi: 10.1016/j.cub.2019.04.020. Epub 2019 May 9.


[Percutaneous screw techniques for the pelvic ring and acetabulum].

Lichte P, Alabdulrhaman H, Pishnamaz M, Hofman M, Hildebrand F, Kobbe P.

Unfallchirurg. 2019 May;122(5):387-403. doi: 10.1007/s00113-019-0648-2. German.


Geriatric Polytrauma-Cardiovascular and Immunologic Response in a Murine Two-Hit Model of Trauma.

Horst K, Höfler J, Martin L, Greven J, Schürholz T, Simon TP, Marx G, Hildebrand F.

J Surg Res. 2019 Sep;241:87-94. doi: 10.1016/j.jss.2019.03.053. Epub 2019 Apr 21.


Microcirculation After Trochanteric Femur Fractures: A Prospective Cohort Study Using Non-invasive Laser-Doppler Spectrophotometry.

Ganse B, Böhle F, Pastor T, Gueorguiev B, Altgassen S, Gradl G, Kim BS, Modabber A, Nebelung S, Hildebrand F, Knobe M.

Front Physiol. 2019 Mar 25;10:236. doi: 10.3389/fphys.2019.00236. eCollection 2019.


Contributing factors in the development of acute lung injury in a murine double hit model.

Störmann P, Becker N, Künnemeyer L, Wutzler S, Vollrath JT, Lustenberger T, Hildebrand F, Marzi I, Relja B.

Eur J Trauma Emerg Surg. 2019 Apr 1. doi: 10.1007/s00068-019-01121-5. [Epub ahead of print]


Pneumonia in severely injured patients with thoracic trauma: results of a retrospective observational multi-centre study.

Wutzler S, Bläsius FM, Störmann P, Lustenberger T, Frink M, Maegele M, Weuster M, Bayer J, Caspers M, Seekamp A, Marzi I, Andruszkow H, Hildebrand F.

Scand J Trauma Resusc Emerg Med. 2019 Mar 14;27(1):31. doi: 10.1186/s13049-019-0608-4.


Monotrauma is associated with enhanced remote inflammatory response and organ damage, while polytrauma intensifies both in porcine trauma model.

Störmann P, Wagner N, Köhler K, Auner B, Simon TP, Pfeifer R, Horst K, Pape HC, Hildebrand F, Wutzler S, Marzi I, Relja B.

Eur J Trauma Emerg Surg. 2019 Mar 12. doi: 10.1007/s00068-019-01098-1. [Epub ahead of print]


Circulating Extracellular Vesicles and Their miR "Barcode" Differentiate Alcohol Drinkers With Liver Injury and Those Without Liver Injury in Severe Trauma Patients.

Eguchi A, Franz N, Kobayashi Y, Iwasa M, Wagner N, Hildebrand F, Takei Y, Marzi I, Relja B.

Front Med (Lausanne). 2019 Feb 25;6:30. doi: 10.3389/fmed.2019.00030. eCollection 2019.


Surgical treatment strategies in pediatric trauma patients: ETC vs. DCO-an analysis of 316 pediatric trauma patients from the TraumaRegister DGU®.

Horst K, Andruszkow H, Weber CD, Pishnamaz M, Knobe M, Bläsius FM, Lichte P, Lefering R, Hildebrand F.

Eur J Trauma Emerg Surg. 2019 Oct;45(5):801-808. doi: 10.1007/s00068-019-01092-7. Epub 2019 Feb 13.


Correction to: A new multiple trauma model of the mouse.

Fitschen-Oestern S, Lippross S, Klueter T, Weuster M, Varoga D, Tohidnezhad M, Pufe T, Rose-John S, Andruszkow H, Hildebrand F, Steubesand N, Seekamp A, Neunaber C.

BMC Musculoskelet Disord. 2019 Feb 11;20(1):72. doi: 10.1186/s12891-018-2330-1. No abstract available.


Plasmid DNA contaminant in molecular reagents.

Wally N, Schneider M, Thannesberger J, Kastner MT, Bakonyi T, Indik S, Rattei T, Bedarf J, Hildebrand F, Law J, Jovel J, Steininger C.

Sci Rep. 2019 Feb 7;9(1):1652. doi: 10.1038/s41598-019-38733-1.


Current Status of helicopter emergency medical services in China: A bibliometric analysis.

Xu D, Luo P, Li S, Pfeifer R, Hildebrand F, Pape HC.

Medicine (Baltimore). 2019 Feb;98(6):e14439. doi: 10.1097/MD.0000000000014439.


Enhanced prehospital volume therapy does not lead to improved outcomes in severely injured patients with severe traumatic brain injury.

Hussmann B, Schoeneberg C, Jungbluth P, Heuer M, Lefering R, Maek T, Hildebrand F, Lendemans S, Pape HC.

BMC Emerg Med. 2019 Jan 23;19(1):13. doi: 10.1186/s12873-019-0221-x.


Antibiotics-induced monodominance of a novel gut bacterial order.

Hildebrand F, Moitinho-Silva L, Blasche S, Jahn MT, Gossmann TI, Huerta-Cepas J, Hercog R, Luetge M, Bahram M, Pryszlak A, Alves RJ, Waszak SM, Zhu A, Ye L, Costea PI, Aalvink S, Belzer C, Forslund SK, Sunagawa S, Hentschel U, Merten C, Patil KR, Benes V, Bork P.

Gut. 2019 Oct;68(10):1781-1790. doi: 10.1136/gutjnl-2018-317715. Epub 2019 Jan 18.


Biomechanical testing of a polycarbonate-urethane-based dynamic instrumentation system under physiological conditions.

Beckmann A, Herren C, Nicolini LF, Grevenstein D, Oikonomidis S, Kobbe P, Hildebrand F, Stoffel M, Markert B, Siewe J.

Clin Biomech (Bristol, Avon). 2019 Jan;61:112-119. doi: 10.1016/j.clinbiomech.2018.12.003. Epub 2018 Dec 6.


Two-Nation Comparison of Classification and Treatment of Subaxial Cervical Spine Fractures: An Internet-Based Multicenter Study Among Spine Surgeons.

Pishnamaz M, Curfs I, Uhing D, Herren C, van Santbrink H, Mueller CA, Scholz M, Lichte P, Rijkers K, Boselie TF, Hildebrand F, Willems PC, Kobbe P.

World Neurosurg. 2019 Mar;123:e125-e132. doi: 10.1016/j.wneu.2018.11.078. Epub 2018 Nov 19.


A computational framework to integrate high-throughput '-omics' datasets for the identification of potential mechanistic links.

Pedersen HK, Forslund SK, Gudmundsdottir V, Petersen AØ, Hildebrand F, Hyötyläinen T, Nielsen T, Hansen T, Bork P, Ehrlich SD, Brunak S, Oresic M, Pedersen O, Nielsen HB.

Nat Protoc. 2018 Dec;13(12):2781-2800. doi: 10.1038/s41596-018-0064-z.


Improve hip fracture outcome in the elderly patient (iHOPE): a study protocol for a pragmatic, multicentre randomised controlled trial to test the efficacy of spinal versus general anaesthesia.

Kowark A, Adam C, Ahrens J, Bajbouj M, Bollheimer C, Borowski M, Dodel R, Dolch M, Hachenberg T, Henzler D, Hildebrand F, Hilgers RD, Hoeft A, Isfort S, Kienbaum P, Knobe M, Knuefermann P, Kranke P, Laufenberg-Feldmann R, Nau C, Neuman MD, Olotu C, Rex C, Rossaint R, Sanders RD, Schmidt R, Schneider F, Siebert H, Skorning M, Spies C, Vicent O, Wappler F, Wirtz DC, Wittmann M, Zacharowski K, Zarbock A, Coburn M; iHOPE study group.

BMJ Open. 2018 Oct 18;8(10):e023609. doi: 10.1136/bmjopen-2018-023609.


What's New in Shock, November 2018?

Bläsius FM, Hildebrand F.

Shock. 2018 Nov;50(5):501-503. doi: 10.1097/SHK.0000000000001223. No abstract available.


Effect of Long-Term Polytrauma on Ventilator-Induced Diaphragmatic Dysfunction in a Piglet Model.

Breuer T, Bruells CS, Horst K, Thiele C, Hildebrand F, Linnartz S, Siegberg T, Frank N, Gayan-Ramirez G, Martin L, Ostareck DH, Marx G, Simon TP.

Shock. 2019 Oct;52(4):443-448. doi: 10.1097/SHK.0000000000001272.


In Reply to "Reliability and Agreement of Different Spine Fracture Classification Systems: Methodologic Issue".

Pishnamaz M, Balosu S, Curfs I, Uhing D, Laubach M, Herren C, Weber CD, Hildebrand F, Willems P, Kobbe P.

World Neurosurg. 2018 Oct;118:384. doi: 10.1016/j.wneu.2018.07.130. No abstract available.


In reply to Mengis et al.

Pishnamaz M, Lange H, Herren C, Na HS, Lichte P, Hildebrand F, Pape HC, Kobbe P.

Clin Biomech (Bristol, Avon). 2018 Nov;59:212-213. doi: 10.1016/j.clinbiomech.2018.09.006. Epub 2018 Sep 5. No abstract available.


[The gut microbiome in Parkinson's disease].

Bedarf JR, Hildebrand F, Goeser F, Bork P, Wüllner U.

Nervenarzt. 2019 Feb;90(2):160-166. doi: 10.1007/s00115-018-0601-6. Review. German.


Population-level analysis of Blastocystis subtype prevalence and variation in the human gut microbiota.

Tito RY, Chaffron S, Caenepeel C, Lima-Mendez G, Wang J, Vieira-Silva S, Falony G, Hildebrand F, Darzi Y, Rymenans L, Verspecht C, Bork P, Vermeire S, Joossens M, Raes J.

Gut. 2019 Jul;68(7):1180-1189. doi: 10.1136/gutjnl-2018-316106. Epub 2018 Aug 31.


Early local microcirculation is improved after intramedullary nailing in comparison to external fixation in a porcine model with a femur fracture.

Kalbas Y, Qiao Z, Horst K, Teuben M, Tolba RH, Hildebrand F, Pape HC, Pfeifer R; TREAT Research Group.

Eur J Trauma Emerg Surg. 2018 Oct;44(5):689-696. doi: 10.1007/s00068-018-0991-y. Epub 2018 Aug 22.


The gut microbiome is associated with behavioural task in honey bees.

Jones JC, Fruciano C, Marchant J, Hildebrand F, Forslund S, Bork P, Engel P, Hughes WOH.

Insectes Soc. 2018;65(3):419-429. doi: 10.1007/s00040-018-0624-9. Epub 2018 May 19.


Structure and function of the global topsoil microbiome.

Bahram M, Hildebrand F, Forslund SK, Anderson JL, Soudzilovskaia NA, Bodegom PM, Bengtsson-Palme J, Anslan S, Coelho LP, Harend H, Huerta-Cepas J, Medema MH, Maltz MR, Mundra S, Olsson PA, Pent M, Põlme S, Sunagawa S, Ryberg M, Tedersoo L, Bork P.

Nature. 2018 Aug;560(7717):233-237. doi: 10.1038/s41586-018-0386-6. Epub 2018 Aug 1.


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