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Items: 46

1.

Intraocular Degradation of XEN45 Gel Stent Three Years After Its Implantation.

Widder RA, Kühnrich P, Hild M, Rennings C, Szumniak A, Rössler GF.

J Glaucoma. 2019 Sep 11. doi: 10.1097/IJG.0000000000001364. [Epub ahead of print]

PMID:
31517762
2.

Correction to Indolyl-Pyridinyl-Propenone-Induced Methuosis through the Inhibition of PIKFYVE.

Cho H, Geno E, Patoor M, Reid A, McDonald RI, Hild M, Jenkins JL.

ACS Omega. 2018 Aug 13;3(8):9034. doi: 10.1021/acsomega.8b01656. eCollection 2018 Aug 31.

3.

Discovery of Small Molecule Splicing Modulators of Survival Motor Neuron-2 (SMN2) for the Treatment of Spinal Muscular Atrophy (SMA).

Cheung AK, Hurley B, Kerrigan R, Shu L, Chin DN, Shen Y, O'Brien G, Sung MJ, Hou Y, Axford J, Cody E, Sun R, Fazal A, Fridrich C, Sanchez CC, Tomlinson RC, Jain M, Deng L, Hoffmaster K, Song C, Van Hoosear M, Shin Y, Servais R, Towler C, Hild M, Curtis D, Dietrich WF, Hamann LG, Briner K, Chen KS, Kobayashi D, Sivasankaran R, Dales NA.

J Med Chem. 2018 Dec 27;61(24):11021-11036. doi: 10.1021/acs.jmedchem.8b01291. Epub 2018 Dec 13.

PMID:
30407821
4.

DRUG-seq for miniaturized high-throughput transcriptome profiling in drug discovery.

Ye C, Ho DJ, Neri M, Yang C, Kulkarni T, Randhawa R, Henault M, Mostacci N, Farmer P, Renner S, Ihry R, Mansur L, Keller CG, McAllister G, Hild M, Jenkins J, Kaykas A.

Nat Commun. 2018 Oct 17;9(1):4307. doi: 10.1038/s41467-018-06500-x.

5.

Indolyl-Pyridinyl-Propenone-Induced Methuosis through the Inhibition of PIKFYVE.

Cho H, Geno E, Patoor M, Reid A, McDonald R, Hild M, Jenkins JL.

ACS Omega. 2018 Jun 30;3(6):6097-6103. doi: 10.1021/acsomega.8b00202. Epub 2018 Jun 5. Erratum in: ACS Omega. 2018 Aug 13;3(8):9034.

6.

High-Throughput Functional Analysis Distinguishes Pathogenic, Nonpathogenic, and Compensatory Transcriptional Changes in Neurodegeneration.

Al-Ramahi I, Lu B, Di Paola S, Pang K, de Haro M, Peluso I, Gallego-Flores T, Malik NT, Erikson K, Bleiberg BA, Avalos M, Fan G, Rivers LE, Laitman AM, Diaz-García JR, Hild M, Palacino J, Liu Z, Medina DL, Botas J.

Cell Syst. 2018 Jul 25;7(1):28-40.e4. doi: 10.1016/j.cels.2018.05.010. Epub 2018 Jun 20.

7.

Size uniformity of animal cells is actively maintained by a p38 MAPK-dependent regulation of G1-length.

Liu S, Ginzberg MB, Patel N, Hild M, Leung B, Li Z, Chen YC, Chang N, Wang Y, Tan C, Diena S, Trimble W, Wasserman L, Jenkins JL, Kirschner MW, Kafri R.

Elife. 2018 Mar 29;7. pii: e26947. doi: 10.7554/eLife.26947.

8.

Production of 3-D Airway Organoids From Primary Human Airway Basal Cells and Their Use in High-Throughput Screening.

Hild M, Jaffe AB.

Curr Protoc Stem Cell Biol. 2016 May 12;37:IE.9.1-IE.9.15. doi: 10.1002/cpsc.1.

PMID:
27171795
9.

Novel fiber-based pure chitosan scaffold for tendon augmentation: biomechanical and cell biological evaluation.

Nowotny J, Aibibu D, Farack J, Nimtschke U, Hild M, Gelinsky M, Kasten P, Cherif Ch.

J Biomater Sci Polym Ed. 2016 Jul;27(10):917-36. doi: 10.1080/09205063.2016.1155879. Epub 2016 Apr 23.

PMID:
27109607
10.

Corrigendum: SMN2 splice modulators enhance U1-pre-mRNA association and rescue SMA mice.

Palacino J, Swalley SE, Song C, Cheung AK, Shu L, Zhang X, Van Hoosear M, Shin Y, Chin DN, Keller CG, Beibel M, Renaud NA, Smith TM, Salcius M, Shi X, Hild M, Servais R, Jain M, Deng L, Bullock C, McLellan M, Schuierer S, Murphy L, Blommers MJ, Blaustein C, Berenshteyn F, Lacoste A, Thomas JR, Roma G, Michaud GA, Tseng BS, Porter JA, Myer VE, Tallarico JA, Hamann LG, Curtis D, Fishman MC, Dietrich WF, Dales NA, Sivasankaran R.

Nat Chem Biol. 2016 Apr;12(4):304. doi: 10.1038/nchembio0416-304c. No abstract available.

PMID:
26991088
11.

Textile cell-free scaffolds for in situ tissue engineering applications.

Aibibu D, Hild M, Wöltje M, Cherif C.

J Mater Sci Mater Med. 2016 Mar;27(3):63. doi: 10.1007/s10856-015-5656-3. Epub 2016 Jan 22. Review.

12.

Corrigendum: SMN2 splice modulators enhance U1-pre-mRNA association and rescue SMA mice.

Palacino J, Swalley SE, Song C, Cheung AK, Shu L, Zhang X, Van Hoosear M, Shin Y, Chin DN, Keller CG, Beibel M, Renaud NA, Smith TM, Salcius M, Shi X, Hild M, Servais R, Jain M, Deng L, Bullock C, McLellan M, Schuierer S, Murphy L, Blommers MJ, Blaustein C, Berenshteyn F, Lacoste A, Thomas JR, Roma G, Michaud GA, Tseng BS, Porter JA, Myer VE, Tallarico JA, Hamann LG, Curtis D, Fishman MC, Dietrich WF, Dales NA, Sivasankaran R.

Nat Chem Biol. 2015 Sep;11(9):741. doi: 10.1038/nchembio0915-741a. No abstract available.

PMID:
26284678
13.

Ipl1/Aurora-B is necessary for kinetochore restructuring in meiosis I in Saccharomyces cerevisiae.

Meyer RE, Chuong HH, Hild M, Hansen CL, Kinter M, Dawson DS.

Mol Biol Cell. 2015 Sep 1;26(17):2986-3000. doi: 10.1091/mbc.E15-01-0032. Epub 2015 Jul 8.

14.

SMN2 splice modulators enhance U1-pre-mRNA association and rescue SMA mice.

Palacino J, Swalley SE, Song C, Cheung AK, Shu L, Zhang X, Van Hoosear M, Shin Y, Chin DN, Keller CG, Beibel M, Renaud NA, Smith TM, Salcius M, Shi X, Hild M, Servais R, Jain M, Deng L, Bullock C, McLellan M, Schuierer S, Murphy L, Blommers MJ, Blaustein C, Berenshteyn F, Lacoste A, Thomas JR, Roma G, Michaud GA, Tseng BS, Porter JA, Myer VE, Tallarico JA, Hamann LG, Curtis D, Fishman MC, Dietrich WF, Dales NA, Sivasankaran R.

Nat Chem Biol. 2015 Jul;11(7):511-7. doi: 10.1038/nchembio.1837. Epub 2015 Jun 1. Erratum in: Nat Chem Biol. 2015 Sep;11(9):741. Nat Chem Biol. 2016 Apr;12(4):304.

PMID:
26030728
15.

Notch2 is required for inflammatory cytokine-driven goblet cell metaplasia in the lung.

Danahay H, Pessotti AD, Coote J, Montgomery BE, Xia D, Wilson A, Yang H, Wang Z, Bevan L, Thomas C, Petit S, London A, LeMotte P, Doelemeyer A, Vélez-Reyes GL, Bernasconi P, Fryer CJ, Edwards M, Capodieci P, Chen A, Hild M, Jaffe AB.

Cell Rep. 2015 Jan 13;10(2):239-52. doi: 10.1016/j.celrep.2014.12.017. Epub 2014 Dec 31.

16.

Structure of the DDB1-CRBN E3 ubiquitin ligase in complex with thalidomide.

Fischer ES, Böhm K, Lydeard JR, Yang H, Stadler MB, Cavadini S, Nagel J, Serluca F, Acker V, Lingaraju GM, Tichkule RB, Schebesta M, Forrester WC, Schirle M, Hassiepen U, Ottl J, Hild M, Beckwith RE, Harper JW, Jenkins JL, Thomä NH.

Nature. 2014 Aug 7;512(7512):49-53. doi: 10.1038/nature13527. Epub 2014 Jul 16.

17.

Identification of NUB1 as a suppressor of mutant Huntington toxicity via enhanced protein clearance.

Lu B, Al-Ramahi I, Valencia A, Wang Q, Berenshteyn F, Yang H, Gallego-Flores T, Ichcho S, Lacoste A, Hild M, Difiglia M, Botas J, Palacino J.

Nat Neurosci. 2013 May;16(5):562-70. doi: 10.1038/nn.3367. Epub 2013 Mar 24.

PMID:
23525043
18.

R-Spondin potentiates Wnt/β-catenin signaling through orphan receptors LGR4 and LGR5.

Ruffner H, Sprunger J, Charlat O, Leighton-Davies J, Grosshans B, Salathe A, Zietzling S, Beck V, Therier M, Isken A, Xie Y, Zhang Y, Hao H, Shi X, Liu D, Song Q, Clay I, Hintzen G, Tchorz J, Bouchez LC, Michaud G, Finan P, Myer VE, Bouwmeester T, Porter J, Hild M, Bassilana F, Parker CN, Cong F.

PLoS One. 2012;7(7):e40976. doi: 10.1371/journal.pone.0040976. Epub 2012 Jul 16.

19.

In vivo analysis of compound activity and mechanism of action using epistasis in Drosophila.

Bangi E, Garza D, Hild M.

J Chem Biol. 2011 Apr;4(2):55-68. doi: 10.1007/s12154-010-0051-5. Epub 2010 Dec 22.

20.

RNF146 is a poly(ADP-ribose)-directed E3 ligase that regulates axin degradation and Wnt signalling.

Zhang Y, Liu S, Mickanin C, Feng Y, Charlat O, Michaud GA, Schirle M, Shi X, Hild M, Bauer A, Myer VE, Finan PM, Porter JA, Huang SM, Cong F.

Nat Cell Biol. 2011 May;13(5):623-9. doi: 10.1038/ncb2222. Epub 2011 Apr 10.

PMID:
21478859
21.
22.

Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling.

Huang SM, Mishina YM, Liu S, Cheung A, Stegmeier F, Michaud GA, Charlat O, Wiellette E, Zhang Y, Wiessner S, Hild M, Shi X, Wilson CJ, Mickanin C, Myer V, Fazal A, Tomlinson R, Serluca F, Shao W, Cheng H, Shultz M, Rau C, Schirle M, Schlegl J, Ghidelli S, Fawell S, Lu C, Curtis D, Kirschner MW, Lengauer C, Finan PM, Tallarico JA, Bouwmeester T, Porter JA, Bauer A, Cong F.

Nature. 2009 Oct 1;461(7264):614-20. doi: 10.1038/nature08356. Epub 2009 Sep 16.

PMID:
19759537
23.

[Unclear deterioration of vision after renal transplant].

Hild M, Walter HS, Milioti G, Seitz B.

Ophthalmologe. 2009 Nov;106(11):1024-8. doi: 10.1007/s00347-009-1989-y. German.

PMID:
19585124
24.

Bidirectional transport of amino acids regulates mTOR and autophagy.

Nicklin P, Bergman P, Zhang B, Triantafellow E, Wang H, Nyfeler B, Yang H, Hild M, Kung C, Wilson C, Myer VE, MacKeigan JP, Porter JA, Wang YK, Cantley LC, Finan PM, Murphy LO.

Cell. 2009 Feb 6;136(3):521-34. doi: 10.1016/j.cell.2008.11.044.

25.

Femtosecond laser-assisted retinal imaging and ablation: experimental pilot study.

Hild M, Krause M, Riemann I, Mestres P, Toropygin S, Löw U, Brückner K, Seitz B, Jonescu-Cuypers C, König K.

Curr Eye Res. 2008 Apr;33(4):351-63. doi: 10.1080/02713680801956452.

PMID:
18398710
26.

In vitro noncontact intravascular femtosecond laser surgery in models of branch retinal vein occlusion.

Toropygin S, Krause M, Riemann I, Hild M, Mestres P, Seitz B, Khurieva E, Ruprecht KW, Löw U, Gatzioufas Z, König K.

Curr Eye Res. 2008 Mar;33(3):277-83. doi: 10.1080/02713680701875299.

PMID:
18350439
27.

Identification of novel modulators of mitochondrial function by a genome-wide RNAi screen in Drosophila melanogaster.

Chen J, Shi X, Padmanabhan R, Wang Q, Wu Z, Stevenson SC, Hild M, Garza D, Li H.

Genome Res. 2008 Jan;18(1):123-36. Epub 2007 Nov 27.

28.

Localized H3K36 methylation states define histone H4K16 acetylation during transcriptional elongation in Drosophila.

Bell O, Wirbelauer C, Hild M, Scharf AN, Schwaiger M, MacAlpine DM, Zilbermann F, van Leeuwen F, Bell SP, Imhof A, Garza D, Peters AH, Schübeler D.

EMBO J. 2007 Dec 12;26(24):4974-84. Epub 2007 Nov 15.

29.

Comparing active and repressed expression states of genes controlled by the Polycomb/Trithorax group proteins.

Beisel C, Buness A, Roustan-Espinosa IM, Koch B, Schmitt S, Haas SA, Hild M, Katsuyama T, Paro R.

Proc Natl Acad Sci U S A. 2007 Oct 16;104(42):16615-20. Epub 2007 Oct 5.

30.

HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS.

Pandey UB, Nie Z, Batlevi Y, McCray BA, Ritson GP, Nedelsky NB, Schwartz SL, DiProspero NA, Knight MA, Schuldiner O, Padmanabhan R, Hild M, Berry DL, Garza D, Hubbert CC, Yao TP, Baehrecke EH, Taylor JP.

Nature. 2007 Jun 14;447(7146):859-63.

PMID:
17568747
31.

Genome-wide RNAi analysis of growth and viability in Drosophila cells.

Boutros M, Kiger AA, Armknecht S, Kerr K, Hild M, Koch B, Haas SA, Paro R, Perrimon N; Heidelberg Fly Array Consortium.

Science. 2004 Feb 6;303(5659):832-5.

32.

An integrated gene annotation and transcriptional profiling approach towards the full gene content of the Drosophila genome.

Hild M, Beckmann B, Haas SA, Koch B, Solovyev V, Busold C, Fellenberg K, Boutros M, Vingron M, Sauer F, Hoheisel JD, Paro R.

Genome Biol. 2003;5(1):R3. Epub 2003 Dec 22.

33.

Genome-scale design of PCR primers and long oligomers for DNA microarrays.

Haas SA, Hild M, Wright AP, Hain T, Talibi D, Vingron M.

Nucleic Acids Res. 2003 Oct 1;31(19):5576-81.

34.

Anti-silencing from the core: a histone H2A variant protects euchromatin.

Hild M, Paro R.

Nat Cell Biol. 2003 Apr;5(4):278-80. Review. No abstract available.

PMID:
12669075
35.
36.

Platelet storage in PAS-2 or autologous plasma: impact on functional parameters.

Bunescu A, Hild M, Lundahl J, Egberg N.

Transfus Med. 2001 Apr;11(2):105-10.

PMID:
11299027
37.

The roles of BMPs, BMP antagonists, and the BMP signaling transducers Smad1 and Smad5 during dorsoventral patterning of the zebrafish embryo.

Hild M, Dick A, Bauer H, Schulte-Merker S, Haffter P, Bouwmeester T, Hammerschmidt M.

Ernst Schering Res Found Workshop. 2000;(29):81-106. Review. No abstract available.

PMID:
10943306
38.

Differential in vitro effects of the platelet glycoprotein IIb/IIIa inhibitors abixicimab or SR121566A on platelet aggregation, fibrinogen binding and platelet secretory parameters.

Klinkhardt U, Kirchmaier CM, Westrup D, Breddin HK, Mahnel R, Graff J, Hild M, Harder S.

Thromb Res. 2000 Feb 15;97(4):201-7.

PMID:
10674406
39.

Essential role of Bmp7 (snailhouse) and its prodomain in dorsoventral patterning of the zebrafish embryo.

Dick A, Hild M, Bauer H, Imai Y, Maifeld H, Schier AF, Talbot WS, Bouwmeester T, Hammerschmidt M.

Development. 2000 Jan;127(2):343-54.

40.

The smad5 mutation somitabun blocks Bmp2b signaling during early dorsoventral patterning of the zebrafish embryo.

Hild M, Dick A, Rauch GJ, Meier A, Bouwmeester T, Haffter P, Hammerschmidt M.

Development. 1999 May;126(10):2149-59.

41.

Follistatin and noggin are excluded from the zebrafish organizer.

Bauer H, Meier A, Hild M, Stachel S, Economides A, Hazelett D, Harland RM, Hammerschmidt M.

Dev Biol. 1998 Dec 15;204(2):488-507.

42.

Kinetics of bradykinin levels during and after leucocyte filtration of platelet concentrates.

Hild M, Söderström T, Egberg N, Lundahl J.

Vox Sang. 1998;75(1):18-25.

PMID:
9745149
43.
44.

Complement activation during blood sampling procedures alters the expression of CD11b/CD18 on human neutrophils.

Wehlin L, Gustavsson K, Halldén G, Emilson A, Svensson A, Hild M, Lundahl J.

Vox Sang. 1998;74(1):21-6.

PMID:
9481856
45.
46.

[Serologic diagnosis and follow-up in patients with uveitis. Antibodies to virulence antigens of Yersinia enterocolitica].

Hild M, Böhnke M, Damms T, Heesemann J.

Fortschr Ophthalmol. 1990;87(5):484-7. German.

PMID:
2272579

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