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Items: 1 to 50 of 271

1.

Interethnic differences in neuroimaging markers and cognition in Asians, a population-based study.

Wong LCK, Wong MYZ, Tan CS, Vrooman H, Venketasubramanian N, Cheng CY, Chen C, Hilal S.

Sci Rep. 2020 Feb 14;10(1):2655. doi: 10.1038/s41598-020-59618-8.

2.

Cerebral microinfarcts affect brain structural network topology in cognitively impaired patients.

Zhang L, Biessels GJ, Hilal S, Chong JSX, Liu S, Shim HY, Xu X, Chong EJY, Wong ZX, Loke YM, Venketasubramanian N, Yeow TB, Chen CL, Zhou JH.

J Cereb Blood Flow Metab. 2020 Jan 27:271678X20902187. doi: 10.1177/0271678X20902187. [Epub ahead of print] No abstract available.

PMID:
31986957
3.

MRI Markers of Mixed Pathology and Cognitive Impairment in Multiethnic Asians.

Tan CH, Hilal S, Xu X, Vrooman H, Cheng CY, Wong TY, Venketasubramanian N, Chen C.

J Alzheimers Dis. 2020;73(4):1501-1509. doi: 10.3233/JAD-190866.

PMID:
31958085
4.

Influence of Comorbidity of Cerebrovascular Disease and Amyloid-β on Alzheimer's Disease.

Yassi N, Hilal S, Xia Y, Lim YY, Watson R, Kuijf H, Fowler C, Yates P, Maruff P, Martins R, Ames D, Chen C, Rowe CC, Villemagne VL, Salvado O, Desmond PM, Masters CL.

J Alzheimers Dis. 2020;73(3):897-907. doi: 10.3233/JAD-191028.

PMID:
31884485
5.

Neuropsychiatric Correlates of Small Vessel Disease Progression in Incident Cognitive Decline: Independent and Interactive Effects.

Kan CN, Gyanwali B, Hilal S, Ng KP, Venketasubramanian N, Chen CL, Xu X.

J Alzheimers Dis. 2020;73(3):1053-1062. doi: 10.3233/JAD-190999.

PMID:
31884482
6.

Hearing handicap in Asian patients with dementia.

Gyanwali B, Hilal S, Venketasubramanian N, Chen C, Loo JHY.

Am J Otolaryngol. 2020 Mar - Apr;41(2):102377. doi: 10.1016/j.amjoto.2019.102377. Epub 2019 Dec 12.

PMID:
31864727
7.

Improved quantification of amyloid burden and associated biomarker cut-off points: results from the first amyloid Singaporean cohort with overlapping cerebrovascular disease.

Tanaka T, Stephenson MC, Nai YH, Khor D, Saridin FN, Hilal S, Villaraza S, Gyanwali B, Ihara M, Vrooman H, Weekes AA, Totman JJ, Robins EG, Chen CP, Reilhac A.

Eur J Nucl Med Mol Imaging. 2020 Feb;47(2):319-331. doi: 10.1007/s00259-019-04642-8. Epub 2019 Dec 20.

PMID:
31863136
8.

Telomere Length and the Risk of Alzheimer's Disease: The Rotterdam Study.

Fani L, Hilal S, Sedaghat S, Broer L, Licher S, Arp PP, van Meurs JBJ, Ikram MK, Ikram MA.

J Alzheimers Dis. 2020;73(2):707-714. doi: 10.3233/JAD-190759.

9.

The prevalence and clinical associations of disproportionately enlarged subarachnoid space hydrocephalus (DESH), an imaging feature of idiopathic normal pressure hydrocephalus in community and memory clinic based Singaporean cohorts.

Akiba C, Gyanwali B, Villaraza S, Nakajima M, Miyajima M, Cheng CY, Wong TY, Venketasubramanian N, Hilal S, Chen C.

J Neurol Sci. 2020 Jan 15;408:116510. doi: 10.1016/j.jns.2019.116510. Epub 2019 Oct 25.

10.

MRI of posterior eye shape and its associations with myopia and ethnicity.

Lim LS, Matsumura S, Htoon HM, Tian J, Lim SB, Sensaki S, Chen C, Hilal S, Wong TY, Cheng CY, Kuo A, Saw SM.

Br J Ophthalmol. 2019 Dec 2. pii: bjophthalmol-2019-315020. doi: 10.1136/bjophthalmol-2019-315020. [Epub ahead of print]

PMID:
31791940
11.

Mixed-location cerebral microbleeds as a biomarker of neurodegeneration in a memory clinic population.

Gyanwali B, Shaik MA, Tan CS, Vrooman H, Venketasubramanian N, Chen C, Hilal S.

Aging (Albany NY). 2019 Nov 25;11(22):10581-10596. doi: 10.18632/aging.102478. Epub 2019 Nov 25.

12.

Additive effect of cerebral atrophy on cognition in dementia-free elderly with cerebrovascular disease.

Xu X, Phua A, Collinson SL, Hilal S, Ikram MK, Wong TY, Cheng CY, Venketasubramanian N, Chen C.

Stroke Vasc Neurol. 2019 Jun 20;4(3):135-140. doi: 10.1136/svn-2018-000202. eCollection 2019 Sep.

13.

Genetic architecture of subcortical brain structures in 38,851 individuals.

Satizabal CL, Adams HHH, Hibar DP, White CC, Knol MJ, Stein JL, Scholz M, Sargurupremraj M, Jahanshad N, Roshchupkin GV, Smith AV, Bis JC, Jian X, Luciano M, Hofer E, Teumer A, van der Lee SJ, Yang J, Yanek LR, Lee TV, Li S, Hu Y, Koh JY, Eicher JD, Desrivières S, Arias-Vasquez A, Chauhan G, Athanasiu L, Rentería ME, Kim S, Hoehn D, Armstrong NJ, Chen Q, Holmes AJ, den Braber A, Kloszewska I, Andersson M, Espeseth T, Grimm O, Abramovic L, Alhusaini S, Milaneschi Y, Papmeyer M, Axelsson T, Ehrlich S, Roiz-Santiañez R, Kraemer B, Håberg AK, Jones HJ, Pike GB, Stein DJ, Stevens A, Bralten J, Vernooij MW, Harris TB, Filippi I, Witte AV, Guadalupe T, Wittfeld K, Mosley TH, Becker JT, Doan NT, Hagenaars SP, Saba Y, Cuellar-Partida G, Amin N, Hilal S, Nho K, Mirza-Schreiber N, Arfanakis K, Becker DM, Ames D, Goldman AL, Lee PH, Boomsma DI, Lovestone S, Giddaluru S, Le Hellard S, Mattheisen M, Bohlken MM, Kasperaviciute D, Schmaal L, Lawrie SM, Agartz I, Walton E, Tordesillas-Gutierrez D, Davies GE, Shin J, Ipser JC, Vinke LN, Hoogman M, Jia T, Burkhardt R, Klein M, Crivello F, Janowitz D, Carmichael O, Haukvik UK, Aribisala BS, Schmidt H, Strike LT, Cheng CY, Risacher SL, Pütz B, Fleischman DA, Assareh AA, Mattay VS, Buckner RL, Mecocci P, Dale AM, Cichon S, Boks MP, Matarin M, Penninx BWJH, Calhoun VD, Chakravarty MM, Marquand AF, Macare C, Kharabian Masouleh S, Oosterlaan J, Amouyel P, Hegenscheid K, Rotter JI, Schork AJ, Liewald DCM, de Zubicaray GI, Wong TY, Shen L, Sämann PG, Brodaty H, Roffman JL, de Geus EJC, Tsolaki M, Erk S, van Eijk KR, Cavalleri GL, van der Wee NJA, McIntosh AM, Gollub RL, Bulayeva KB, Bernard M, Richards JS, Himali JJ, Loeffler M, Rommelse N, Hoffmann W, Westlye LT, Valdés Hernández MC, Hansell NK, van Erp TGM, Wolf C, Kwok JBJ, Vellas B, Heinz A, Olde Loohuis LM, Delanty N, Ho BC, Ching CRK, Shumskaya E, Singh B, Hofman A, van der Meer D, Homuth G, Psaty BM, Bastin ME, Montgomery GW, Foroud TM, Reppermund S, Hottenga JJ, Simmons A, Meyer-Lindenberg A, Cahn W, Whelan CD, van Donkelaar MMJ, Yang Q, Hosten N, Green RC, Thalamuthu A, Mohnke S, Hulshoff Pol HE, Lin H, Jack CR Jr, Schofield PR, Mühleisen TW, Maillard P, Potkin SG, Wen W, Fletcher E, Toga AW, Gruber O, Huentelman M, Davey Smith G, Launer LJ, Nyberg L, Jönsson EG, Crespo-Facorro B, Koen N, Greve DN, Uitterlinden AG, Weinberger DR, Steen VM, Fedko IO, Groenewold NA, Niessen WJ, Toro R, Tzourio C, Longstreth WT Jr, Ikram MK, Smoller JW, van Tol MJ, Sussmann JE, Paus T, Lemaître H, Schroeter ML, Mazoyer B, Andreassen OA, Holsboer F, Depondt C, Veltman DJ, Turner JA, Pausova Z, Schumann G, van Rooij D, Djurovic S, Deary IJ, McMahon KL, Müller-Myhsok B, Brouwer RM, Soininen H, Pandolfo M, Wassink TH, Cheung JW, Wolfers T, Martinot JL, Zwiers MP, Nauck M, Melle I, Martin NG, Kanai R, Westman E, Kahn RS, Sisodiya SM, White T, Saremi A, van Bokhoven H, Brunner HG, Völzke H, Wright MJ, van 't Ent D, Nöthen MM, Ophoff RA, Buitelaar JK, Fernández G, Sachdev PS, Rietschel M, van Haren NEM, Fisher SE, Beiser AS, Francks C, Saykin AJ, Mather KA, Romanczuk-Seiferth N, Hartman CA, DeStefano AL, Heslenfeld DJ, Weiner MW, Walter H, Hoekstra PJ, Nyquist PA, Franke B, Bennett DA, Grabe HJ, Johnson AD, Chen C, van Duijn CM, Lopez OL, Fornage M, Wardlaw JM, Schmidt R, DeCarli C, De Jager PL, Villringer A, Debette S, Gudnason V, Medland SE, Shulman JM, Thompson PM, Seshadri S, Ikram MA.

Nat Genet. 2019 Nov;51(11):1624-1636. doi: 10.1038/s41588-019-0511-y. Epub 2019 Oct 21.

PMID:
31636452
14.

Enlarged Perivascular Spaces and Dementia: A Systematic Review.

Smeijer D, Ikram MK, Hilal S.

J Alzheimers Dis. 2019;72(1):247-256. doi: 10.3233/JAD-190527.

15.

Cortical microinfarcts in memory clinic patients are associated with reduced cerebral perfusion.

Ferro DA, Mutsaerts HJ, Hilal S, Kuijf HJ, Petersen ET, Petr J, van Veluw SJ, Venketasubramanian N, Yeow TB, Biessels GJ, Chen C.

J Cereb Blood Flow Metab. 2019 Sep 26:271678X19877403. doi: 10.1177/0271678X19877403. [Epub ahead of print]

PMID:
31558107
16.

Mixed-Location Cerebral Microbleeds: An Imaging Biomarker for Cerebrovascular Pathology in Cognitive Impairment and Dementia in a Memory Clinic Population.

Gyanwali B, Shaik MA, Venketasubramanian N, Chen C, Hilal S.

J Alzheimers Dis. 2019;71(4):1309-1320. doi: 10.3233/JAD-190540.

PMID:
31524167
17.

A genome-wide association study identifies genetic loci associated with specific lobar brain volumes.

van der Lee SJ, Knol MJ, Chauhan G, Satizabal CL, Smith AV, Hofer E, Bis JC, Hibar DP, Hilal S, van den Akker EB, Arfanakis K, Bernard M, Yanek LR, Amin N, Crivello F, Cheung JW, Harris TB, Saba Y, Lopez OL, Li S, van der Grond J, Yu L, Paus T, Roshchupkin GV, Amouyel P, Jahanshad N, Taylor KD, Yang Q, Mathias RA, Boehringer S, Mazoyer B, Rice K, Cheng CY, Maillard P, van Heemst D, Wong TY, Niessen WJ, Beiser AS, Beekman M, Zhao W, Nyquist PA, Chen C, Launer LJ, Psaty BM, Ikram MK, Vernooij MW, Schmidt H, Pausova Z, Becker DM, De Jager PL, Thompson PM, van Duijn CM, Bennett DA, Slagboom PE, Schmidt R, Longstreth WT, Ikram MA, Seshadri S, Debette S, Gudnason V, Adams HHH, DeCarli C.

Commun Biol. 2019 Aug 2;2:285. doi: 10.1038/s42003-019-0537-9. eCollection 2019.

18.

Prevalence and clinical relevance of diffusion-weighted imaging lesions: The Rotterdam study.

Hilal S, Baaij LGA, de Groot M, Niessen WJ, Ikram MK, Ikram MA, Vernooij MW.

Neurology. 2019 Sep 10;93(11):e1058-e1067. doi: 10.1212/WNL.0000000000008090. Epub 2019 Aug 7.

PMID:
31391244
19.

Prevalence and Risk Factors for Cognitive Impairment and Dementia in Indians: A Multiethnic Perspective from a Singaporean Study.

Wong MYZ, Tan CS, Venketasubramanian N, Chen C, Ikram MK, Cheng CY, Hilal S.

J Alzheimers Dis. 2019;71(1):341-351. doi: 10.3233/JAD-190610.

PMID:
31381520
20.

Cerebral Small Vessel Disease and Enlarged Perivascular Spaces-Data From Memory Clinic and Population-Based Settings.

Gyanwali B, Vrooman H, Venketasubramanian N, Wong TY, Cheng CY, Chen C, Hilal S.

Front Neurol. 2019 Jun 25;10:669. doi: 10.3389/fneur.2019.00669. eCollection 2019.

21.

APOE and cortical superficial siderosis in CAA: Meta-analysis and potential mechanisms.

Charidimou A, Zonneveld HI, Shams S, Kantarci K, Shoamanesh A, Hilal S, Yates PA, Boulouis G, Na HK, Pasi M, Biffi A, Chai YL, Chong JR, Wahlund LO, Clifford JR, Chen C, Gurol ME, Goldstein JN, Na DL, Barkhof F, Seo SW, Rosand J, Greenberg SM, Viswanathan A.

Neurology. 2019 Jul 23;93(4):e358-e371. doi: 10.1212/WNL.0000000000007818. Epub 2019 Jun 26.

PMID:
31243071
22.

Cerebral microbleeds and stroke risk after ischaemic stroke or transient ischaemic attack: a pooled analysis of individual patient data from cohort studies.

Wilson D, Ambler G, Lee KJ, Lim JS, Shiozawa M, Koga M, Li L, Lovelock C, Chabriat H, Hennerici M, Wong YK, Mak HKF, Prats-Sánchez L, Martínez-Domeño A, Inamura S, Yoshifuji K, Arsava EM, Horstmann S, Purrucker J, Lam BYK, Wong A, Kim YD, Song TJ, Schrooten M, Lemmens R, Eppinger S, Gattringer T, Uysal E, Tanriverdi Z, Bornstein NM, Assayag EB, Hallevi H, Tanaka J, Hara H, Coutts SB, Hert L, Polymeris A, Seiffge DJ, Lyrer P, Algra A, Kappelle J, Al-Shahi Salman R, Jäger HR, Lip GYH, Mattle HP, Panos LD, Mas JL, Legrand L, Karayiannis C, Phan T, Gunkel S, Christ N, Abrigo J, Leung T, Chu W, Chappell F, Makin S, Hayden D, Williams DJ, Kooi ME, van Dam-Nolen DHK, Barbato C, Browning S, Wiegertjes K, Tuladhar AM, Maaijwee N, Guevarra C, Yatawara C, Mendyk AM, Delmaire C, Köhler S, van Oostenbrugge R, Zhou Y, Xu C, Hilal S, Gyanwali B, Chen C, Lou M, Staals J, Bordet R, Kandiah N, de Leeuw FE, Simister R, van der Lugt A, Kelly PJ, Wardlaw JM, Soo Y, Fluri F, Srikanth V, Calvet D, Jung S, Kwa VIH, Engelter ST, Peters N, Smith EE, Yakushiji Y, Orken DN, Fazekas F, Thijs V, Heo JH, Mok V, Veltkamp R, Ay H, Imaizumi T, Gomez-Anson B, Lau KK, Jouvent E, Rothwell PM, Toyoda K, Bae HJ, Marti-Fabregas J, Werring DJ; Microbleeds International Collaborative Network.

Lancet Neurol. 2019 Jul;18(7):653-665. doi: 10.1016/S1474-4422(19)30197-8. Epub 2019 May 23. Erratum in: Lancet Neurol. 2019 Sep;18(9):e8. Lancet Neurol. 2020 Feb;19(2):e2.

23.

Mechanisms Linking White Matter Lesions, Tract Integrity, and Depression in Alzheimer Disease.

Yatawara C, Lee D, Ng KP, Chander R, Ng D, Ji F, Shim HY, Hilal S, Venketasubramanian N, Chen C, Zhou J, Kandiah N.

Am J Geriatr Psychiatry. 2019 Sep;27(9):948-959. doi: 10.1016/j.jagp.2019.04.004. Epub 2019 Apr 18.

PMID:
31109898
24.

The Meta VCI Map consortium for meta-analyses on strategic lesion locations for vascular cognitive impairment using lesion-symptom mapping: Design and multicenter pilot study.

Weaver NA, Zhao L, Biesbroek JM, Kuijf HJ, Aben HP, Bae HJ, Caballero MÁA, Chappell FM, Chen CPLH, Dichgans M, Duering M, Georgakis MK, van der Giessen RS, Gyanwali B, Hamilton OKL, Hilal S, Vom Hofe EM, de Kort PLM, Koudstaal PJ, Lam BYK, Lim JS, Makin SDJ, Mok VCT, Shi L, Valdés Hernández MC, Venketasubramanian N, Wardlaw JM, Wollenweber FA, Wong A, Xin X; Meta VCI Map consortium, Biessels GJ.

Alzheimers Dement (Amst). 2019 Apr 12;11:310-326. doi: 10.1016/j.dadm.2019.02.007. eCollection 2019 Dec.

25.

Cortical cerebral microinfarcts predict cognitive decline in memory clinic patients.

Hilal S, Tan CS, van Veluw SJ, Xu X, Vrooman H, Tan BY, Venketasubramanian N, Biessels GJ, Chen C.

J Cereb Blood Flow Metab. 2020 Jan;40(1):44-53. doi: 10.1177/0271678X19835565. Epub 2019 Mar 19.

PMID:
30890075
26.

Risk Factors for and Clinical Relevance of Incident and Progression of Cerebral Small Vessel Disease Markers in an Asian Memory Clinic Population.

Gyanwali B, Shaik MA, Tan BY, Venketasubramanian N, Chen C, Hilal S.

J Alzheimers Dis. 2019;67(4):1209-1219. doi: 10.3233/JAD-180911.

PMID:
30714960
27.

Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting.

Chauhan G, Adams HHH, Satizabal CL, Bis JC, Teumer A, Sargurupremraj M, Hofer E, Trompet S, Hilal S, Smith AV, Jian X, Malik R, Traylor M, Pulit SL, Amouyel P, Mazoyer B, Zhu YC, Kaffashian S, Schilling S, Beecham GW, Montine TJ, Schellenberg GD, Kjartansson O, Guðnason V, Knopman DS, Griswold ME, Windham BG, Gottesman RF, Mosley TH, Schmidt R, Saba Y, Schmidt H, Takeuchi F, Yamaguchi S, Nabika T, Kato N, Rajan KB, Aggarwal NT, De Jager PL, Evans DA, Psaty BM, Rotter JI, Rice K, Lopez OL, Liao J, Chen C, Cheng CY, Wong TY, Ikram MK, van der Lee SJ, Amin N, Chouraki V, DeStefano AL, Aparicio HJ, Romero JR, Maillard P, DeCarli C, Wardlaw JM, Hernández MDCV, Luciano M, Liewald D, Deary IJ, Starr JM, Bastin ME, Muñoz Maniega S, Slagboom PE, Beekman M, Deelen J, Uh HW, Lemmens R, Brodaty H, Wright MJ, Ames D, Boncoraglio GB, Hopewell JC, Beecham AH, Blanton SH, Wright CB, Sacco RL, Wen W, Thalamuthu A, Armstrong NJ, Chong E, Schofield PR, Kwok JB, van der Grond J, Stott DJ, Ford I, Jukema JW, Vernooij MW, Hofman A, Uitterlinden AG, van der Lugt A, Wittfeld K, Grabe HJ, Hosten N, von Sarnowski B, Völker U, Levi C, Jimenez-Conde J, Sharma P, Sudlow CLM, Rosand J, Woo D, Cole JW, Meschia JF, Slowik A, Thijs V, Lindgren A, Melander O, Grewal RP, Rundek T, Rexrode K, Rothwell PM, Arnett DK, Jern C, Johnson JA, Benavente OR, Wasssertheil-Smoller S, Lee JM, Wong Q, Mitchell BD, Rich SS, McArdle PF, Geerlings MI, van der Graaf Y, de Bakker PIW, Asselbergs FW, Srikanth V, Thomson R, McWhirter R, Moran C, Callisaya M, Phan T, Rutten-Jacobs LCA, Bevan S, Tzourio C, Mather KA, Sachdev PS, van Duijn CM, Worrall BB, Dichgans M, Kittner SJ, Markus HS, Ikram MA, Fornage M, Launer LJ, Seshadri S, Longstreth WT Jr, Debette S; Stroke Genetics Network (SiGN), the International Stroke Genetics Consortium (ISGC), METASTROKE, Alzheimer's Disease Genetics Consortium (ADGC), and the Neurology Working Group of the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium.

Neurology. 2019 Jan 16. pii: 10.1212/WNL.0000000000006851. doi: 10.1212/WNL.0000000000006851. [Epub ahead of print]

28.

Alterations in Brain Network Topology and Structural-Functional Connectome Coupling Relate to Cognitive Impairment.

Wang J, Khosrowabadi R, Ng KK, Hong Z, Chong JSX, Wang Y, Chen CY, Hilal S, Venketasubramanian N, Wong TY, Chen CL, Ikram MK, Zhou J.

Front Aging Neurosci. 2018 Dec 13;10:404. doi: 10.3389/fnagi.2018.00404. eCollection 2018.

29.

Haemoglobin, magnetic resonance imaging markers and cognition: a subsample of population-based study.

Tan B, Venketasubramanian N, Vrooman H, Cheng CY, Wong TY, Chen C, Hilal S.

Alzheimers Res Ther. 2018 Nov 6;10(1):114. doi: 10.1186/s13195-018-0440-5.

30.

C-Reactive Protein, Plasma Amyloid-β Levels, and Their Interaction With Magnetic Resonance Imaging Markers.

Hilal S, Ikram MA, Verbeek MM, Franco OH, Stoops E, Vanderstichele H, Niessen WJ, Vernooij MW.

Stroke. 2018 Nov;49(11):2692-2698. doi: 10.1161/STROKEAHA.118.022317.

PMID:
30355213
31.

Cerebrovascular disease influences functional and structural network connectivity in patients with amnestic mild cognitive impairment and Alzheimer's disease.

Vipin A, Loke YM, Liu S, Hilal S, Shim HY, Xu X, Tan BY, Venketasubramanian N, Chen CL, Zhou J.

Alzheimers Res Ther. 2018 Aug 18;10(1):82. doi: 10.1186/s13195-018-0413-8.

32.

Prevalence and association of syphilis reactivity in an Asian memory clinic population.

Gyanwali B, Shaik MA, Hilal S, Cano J, Chen C, Venketasubramanian N.

Int J STD AIDS. 2018 Aug 2:956462418787627. doi: 10.1177/0956462418787627. [Epub ahead of print]

PMID:
30071796
33.

Enlarged perivascular spaces and cognition: A meta-analysis of 5 population-based studies.

Hilal S, Tan CS, Adams HHH, Habes M, Mok V, Venketasubramanian N, Hofer E, Ikram MK, Abrigo J, Vernooij MW, Chen C, Hosten N, Volzke H, Grabe HJ, Schmidt R, Ikram MA.

Neurology. 2018 Aug 28;91(9):e832-e842. doi: 10.1212/WNL.0000000000006079. Epub 2018 Aug 1. Review.

34.

Plasma amyloid-β levels, cerebral atrophy and risk of dementia: a population-based study.

Hilal S, Wolters FJ, Verbeek MM, Vanderstichele H, Ikram MK, Stoops E, Ikram MA, Vernooij MW.

Alzheimers Res Ther. 2018 Jun 30;10(1):63. doi: 10.1186/s13195-018-0395-6.

35.

Global cerebrovascular burden and long-term clinical outcomes in Asian elderly across the spectrum of cognitive impairment.

Xu X, Chan YH, Chan QL, Gyanwali B, Hilal S, Tan BY, Ikram MK, Venketasubramanian N, Chen CL.

Int Psychogeriatr. 2018 Sep;30(9):1355-1363. doi: 10.1017/S1041610217002952. Epub 2018 Apr 18.

PMID:
29665875
36.

Homocysteine and Cerebral Atrophy: The Epidemiology of Dementia in Singapore Study.

Tan B, Venketasubramanian N, Vrooman H, Cheng CY, Wong TY, Ikram MK, Chen C, Hilal S.

J Alzheimers Dis. 2018;62(2):877-885. doi: 10.3233/JAD-170796.

PMID:
29480177
37.

Serum Hepatocyte Growth Factor Is Associated with Small Vessel Disease in Alzheimer's Dementia.

Zhu Y, Hilal S, Chai YL, Ikram MK, Venketasubramanian N, Chen CP, Lai MKP.

Front Aging Neurosci. 2018 Jan 23;10:8. doi: 10.3389/fnagi.2018.00008. eCollection 2018.

38.

Coronal CT is Comparable to MR Imaging in Aiding Diagnosis of Dementia in a Memory Clinic in Singapore.

Thiagarajan S, Shaik MA, Venketasubramanian N, Ting EYS, Hilal S, Chen C.

Alzheimer Dis Assoc Disord. 2018 Apr-Jun;32(2):94-100. doi: 10.1097/WAD.0000000000000227.

PMID:
29200011
39.

Demonstration of a consensus approach for the calculation of physicochemical properties required for environmental fate assessments.

Tebes-Stevens C, Patel JM, Koopmans M, Olmstead J, Hilal SH, Pope N, Weber EJ, Wolfe K.

Chemosphere. 2018 Mar;194:94-106. doi: 10.1016/j.chemosphere.2017.11.137. Epub 2017 Nov 23.

40.

Influence of cerebrovascular disease on brain networks in prodromal and clinical Alzheimer's disease.

Chong JSX, Liu S, Loke YM, Hilal S, Ikram MK, Xu X, Tan BY, Venketasubramanian N, Chen CL, Zhou J.

Brain. 2017 Nov 1;140(11):3012-3022. doi: 10.1093/brain/awx224.

41.

Plasma Amyloid-β Levels, Cerebral Small Vessel Disease, and Cognition: The Rotterdam Study.

Hilal S, Akoudad S, van Duijn CM, Niessen WJ, Verbeek MM, Vanderstichele H, Stoops E, Ikram MA, Vernooij MW.

J Alzheimers Dis. 2017;60(3):977-987. doi: 10.3233/JAD-170458.

PMID:
28984600
42.

Repeatability and Reproducibility of Retinal Neuronal and Axonal Measures on Spectral-Domain Optical Coherence Tomography in Patients with Cognitive Impairment.

Loh EH, Ong YT, Venketasubramanian N, Hilal S, Thet N, Wong TY, Chen CPL, Cheung CY.

Front Neurol. 2017 Aug 15;8:359. doi: 10.3389/fneur.2017.00359. eCollection 2017.

43.

Distinct white matter microstructural abnormalities and extracellular water increases relate to cognitive impairment in Alzheimer's disease with and without cerebrovascular disease.

Ji F, Pasternak O, Liu S, Loke YM, Choo BL, Hilal S, Xu X, Ikram MK, Venketasubramanian N, Chen CL, Zhou J.

Alzheimers Res Ther. 2017 Aug 17;9(1):63. doi: 10.1186/s13195-017-0292-4.

44.

Ankle brachial index, MRI markers and cognition: The Epidemiology of Dementia in Singapore study.

Shaik MA, Venketasubramanian N, Cheng CY, Wong TY, Vrooman H, Ikram MK, Hilal S, Chen C.

Atherosclerosis. 2017 Aug;263:272-277. doi: 10.1016/j.atherosclerosis.2017.07.002. Epub 2017 Jul 5.

PMID:
28709046
45.

Prevalence, risk factors and consequences of cerebral small vessel diseases: data from three Asian countries.

Hilal S, Mok V, Youn YC, Wong A, Ikram MK, Chen CL.

J Neurol Neurosurg Psychiatry. 2017 Aug;88(8):669-674. doi: 10.1136/jnnp-2016-315324. Epub 2017 Jun 9.

PMID:
28600443
46.

Serum IL-8 is a marker of white-matter hyperintensities in patients with Alzheimer's disease.

Zhu Y, Chai YL, Hilal S, Ikram MK, Venketasubramanian N, Wong BS, Chen CP, Lai MK.

Alzheimers Dement (Amst). 2017 Jan 23;7:41-47. doi: 10.1016/j.dadm.2017.01.001. eCollection 2017.

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Association Between Subclinical Cardiac Biomarkers and Clinically Manifest Cardiac Diseases With Cortical Cerebral Microinfarcts.

Hilal S, Chai YL, van Veluw S, Shaik MA, Ikram MK, Venketasubramanian N, Richards AM, Biessels GJ, Chen C.

JAMA Neurol. 2017 Apr 1;74(4):403-410. doi: 10.1001/jamaneurol.2016.5335.

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Impact of Strategically Located White Matter Hyperintensities on Cognition in Memory Clinic Patients with Small Vessel Disease.

Biesbroek JM, Weaver NA, Hilal S, Kuijf HJ, Ikram MK, Xu X, Tan BY, Venketasubramanian N, Postma A, Biessels GJ, Chen CP.

PLoS One. 2016 Nov 8;11(11):e0166261. doi: 10.1371/journal.pone.0166261. eCollection 2016.

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Novel genetic loci underlying human intracranial volume identified through genome-wide association.

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Nat Neurosci. 2016 Dec;19(12):1569-1582. doi: 10.1038/nn.4398. Epub 2016 Oct 3.

50.

Cortical cerebral microinfarcts on 3T MRI: A novel marker of cerebrovascular disease.

Hilal S, Sikking E, Shaik MA, Chan QL, van Veluw SJ, Vrooman H, Cheng CY, Sabanayagam C, Cheung CY, Wong TY, Venketasubramanian N, Biessels GJ, Chen C, Ikram MK.

Neurology. 2016 Oct 11;87(15):1583-1590. Epub 2016 Sep 2.

PMID:
27590296

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