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Items: 1 to 50 of 73

1.

Tamoxifen inhibits the proliferation of non‑melanoma skin cancer cells by increasing intracellular calcium concentration.

Hasegawa G, Akatsuka K, Nakashima Y, Yokoe Y, Higo N, Shimonaka M.

Int J Oncol. 2018 Nov;53(5):2157-2166. doi: 10.3892/ijo.2018.4548. Epub 2018 Aug 31.

PMID:
30226592
2.

Functional near-infrared spectroscopy for monitoring macaque cerebral motor activity during voluntary movements without head fixation.

Yamada T, Kawaguchi H, Kato J, Matsuda K, Higo N.

Sci Rep. 2018 Aug 9;8(1):11941. doi: 10.1038/s41598-018-30416-7.

3.

Expression of SOX9 Is Related to Prognosis in Patients with Oesophageal Squamous Cell Carcinoma.

Higo N, Okumura H, Uchikado Y, Omoto I, Sasaki K, Kita Y, Ryosuke D, Noda M, Owaki T, Ishigami S, Natsugoe S.

In Vivo. 2018 Jul-Aug;32(4):835-838. doi: 10.21873/invivo.11316.

4.

Gaps in Understanding Mechanism and Lack of Treatments: Potential Use of a Nonhuman Primate Model of Oxaliplatin-Induced Neuropathic Pain.

Hama A, Natsume T, Ogawa S, Higo N, Hayashi I, Takamatsu H.

Pain Res Manag. 2018 May 2;2018:1630709. doi: 10.1155/2018/1630709. eCollection 2018. Review.

5.

CRMP2-binding compound, edonerpic maleate, accelerates motor function recovery from brain damage.

Abe H, Jitsuki S, Nakajima W, Murata Y, Jitsuki-Takahashi A, Katsuno Y, Tada H, Sano A, Suyama K, Mochizuki N, Komori T, Masuyama H, Okuda T, Goshima Y, Higo N, Takahashi T.

Science. 2018 Apr 6;360(6384):50-57. doi: 10.1126/science.aao2300.

PMID:
29622647
6.

Comprehensive analysis of area-specific and time-dependent changes in gene expression in the motor cortex of macaque monkeys during recovery from spinal cord injury.

Higo N, Sato A, Yamamoto T, Oishi T, Nishimura Y, Murata Y, Onoe H, Isa T, Kojima T.

J Comp Neurol. 2018 May 1;526(7):1110-1130. doi: 10.1002/cne.24396. Epub 2018 Feb 6.

PMID:
29355954
7.

Late-onset hypersensitivity after a lesion in the ventral posterolateral nucleus of the thalamus: A macaque model of central post-stroke pain.

Nagasaka K, Takashima I, Matsuda K, Higo N.

Sci Rep. 2017 Sep 4;7(1):10316. doi: 10.1038/s41598-017-10679-2.

8.

Brain activity changes in a macaque model of oxaliplatin-induced neuropathic cold hypersensitivity.

Nagasaka K, Yamanaka K, Ogawa S, Takamatsu H, Higo N.

Sci Rep. 2017 Jun 27;7(1):4305. doi: 10.1038/s41598-017-04677-7.

9.

Expression of secreted phosphoprotein 1 (osteopontin) in human sensorimotor cortex and spinal cord: Changes in patients with amyotrophic lateral sclerosis.

Yamamoto T, Murayama S, Takao M, Isa T, Higo N.

Brain Res. 2017 Jan 15;1655:168-175. doi: 10.1016/j.brainres.2016.10.030. Epub 2016 Nov 5.

PMID:
27823929
10.

Optimum Dose of Once-Daily Oxybutynin Patch in Japanese Patients with Overactive Bladder: A Randomized Double-Blind Trial Versus Placebo.

Yamaguchi O, Uchida E, Higo N, Minami H, Kobayashi S, Sato H; Oxybutynin Patch Study Group.

Low Urin Tract Symptoms. 2016 Sep;8(3):150-8. doi: 10.1111/luts.12088. Epub 2015 Feb 12.

PMID:
27619779
11.

Neural Activity during Voluntary Movements in Each Body Representation of the Intracortical Microstimulation-Derived Map in the Macaque Motor Cortex.

Higo N, Kunori N, Murata Y.

PLoS One. 2016 Aug 5;11(8):e0160720. doi: 10.1371/journal.pone.0160720. eCollection 2016.

12.

Effect of Combination of Low-Frequency Sonophoresis or Electroporation with Iontophoresis on the Mannitol Flux or Electroosmosis through Excised Skin.

Tokumoto S, Higo N, Todo H, Sugibayashi K.

Biol Pharm Bull. 2016;39(7):1206-10. doi: 10.1248/bpb.b15-00696.

13.

Development and Characterization of a Macaque Model of Focal Internal Capsular Infarcts.

Murata Y, Higo N.

PLoS One. 2016 May 5;11(5):e0154752. doi: 10.1371/journal.pone.0154752. eCollection 2016.

14.

Pancreaticogastrostomy after Pancreaticoduodenectomy Using Twin Square Wrapping with Duct-to-Mucosa Anastomosis.

Maemura K, Mataki Y, Kurahara H, Mori S, Higo N, Sakoda M, Iino S, Nakajo A, Ishigami S, Ueno S, Takao S, Shinchi H, Natsugoe S.

Eur Surg Res. 2015;55(1-2):109-18. doi: 10.1159/000433425. Epub 2015 Jun 16.

PMID:
26087709
15.

Increased expression of the growth-associated protein-43 gene after primary motor cortex lesion in macaque monkeys.

Murata Y, Higo N, Oishi T, Isa T.

Neurosci Res. 2015 Sep;98:64-9. doi: 10.1016/j.neures.2015.04.007. Epub 2015 May 7.

PMID:
25959053
16.

Once-daily oxybutynin patch improves nocturia and sleep quality in Japanese patients with overactive bladder: Post-hoc analysis of a phase III randomized clinical trial.

Yokoyama O, Yamaguchi A, Yoshida M, Yamanishi T, Ishizuka O, Seki N, Takahashi S, Yamaguchi O, Higo N, Minami H, Masegi Y.

Int J Urol. 2015 Jul;22(7):684-8. doi: 10.1111/iju.12755. Epub 2015 Mar 17.

17.

Temporal plasticity involved in recovery from manual dexterity deficit after motor cortex lesion in macaque monkeys.

Murata Y, Higo N, Hayashi T, Nishimura Y, Sugiyama Y, Oishi T, Tsukada H, Isa T, Onoe H.

J Neurosci. 2015 Jan 7;35(1):84-95. doi: 10.1523/JNEUROSCI.1737-14.2015.

18.

Interpersonal similarity between body movements in face-to-face communication in daily life.

Higo N, Ogawa K, Minemura J, Xu B, Nozawa T, Ogata T, Ara K, Yano K, Miyake Y.

PLoS One. 2014 Jul 11;9(7):e102019. doi: 10.1371/journal.pone.0102019. eCollection 2014.

19.

Elimination of ketoprofen from the stratum corneum after topical administration with ketoprofen formulations in human subjects.

Takeshi M, Ebihara T, Maekawa K, Yamamoto K, Higo N.

Int J Pharm. 2014 Apr 25;465(1-2):197-201. doi: 10.1016/j.ijpharm.2014.02.015. Epub 2014 Feb 12.

PMID:
24530385
20.

Efficacy and safety of once-daily oxybutynin patch versus placebo and propiverine in Japanese patients with overactive bladder: A randomized double-blind trial.

Yamaguchi O, Uchida E, Higo N, Minami H, Kobayashi S, Sato H; Oxybutynin Patch Study Group.

Int J Urol. 2014 Jun;21(6):586-93. doi: 10.1111/iju.12372. Epub 2013 Dec 18.

21.

Strategies to understand and overcome brain/spinal cord injury.

Higo N, Isa T.

Neurosci Res. 2014 Jan;78:1-2. doi: 10.1016/j.neures.2013.11.001. Epub 2013 Nov 11. No abstract available.

PMID:
24231310
22.

Effects of rehabilitative training on recovery of hand motor function: a review of animal studies.

Higo N.

Neurosci Res. 2014 Jan;78:9-15. doi: 10.1016/j.neures.2013.09.008. Epub 2013 Sep 27. Review.

23.

Differential expression of secreted phosphoprotein 1 in the motor cortex among primate species and during postnatal development and functional recovery.

Yamamoto T, Oishi T, Higo N, Murayama S, Sato A, Takashima I, Sugiyama Y, Nishimura Y, Murata Y, Yoshino-Saito K, Isa T, Kojima T.

PLoS One. 2013 May 31;8(5):e65701. doi: 10.1371/journal.pone.0065701. Print 2013.

24.

Effects of early versus late rehabilitative training on manual dexterity after corticospinal tract lesion in macaque monkeys.

Sugiyama Y, Higo N, Yoshino-Saito K, Murata Y, Nishimura Y, Oishi T, Isa T.

J Neurophysiol. 2013 Jun;109(12):2853-65. doi: 10.1152/jn.00814.2012. Epub 2013 Mar 20.

25.

Functional annotation of genes differentially expressed between primary motor and prefrontal association cortices of macaque brain.

Kojima T, Higo N, Sato A, Oishi T, Nishimura Y, Yamamoto T, Murata Y, Yoshino-Saito K, Onoe H, Isa T.

Neurochem Res. 2013 Jan;38(1):133-40. doi: 10.1007/s11064-012-0900-4. Epub 2012 Oct 10.

PMID:
23054074
26.

SPP1 expression in spinal motor neurons of the macaque monkey.

Yamamoto T, Higo N, Sato A, Nishimura Y, Oishi T, Murata Y, Yoshino-Saito K, Isa T, Kojima T.

Neurosci Res. 2011 Jan;69(1):81-6. doi: 10.1016/j.neures.2010.09.010. Epub 2010 Oct 8.

PMID:
20934467
27.

SPP1 is expressed in corticospinal neurons of the macaque sensorimotor cortex.

Higo N, Sato A, Yamamoto T, Nishimura Y, Oishi T, Murata Y, Onoe H, Yoshino-Saito K, Tsuboi F, Takahashi M, Isa T, Kojima T.

J Comp Neurol. 2010 Jul 1;518(13):2633-44. doi: 10.1002/cne.22356.

PMID:
20503431
28.

c-Fos expression during temporal order judgment in mice.

Wada M, Higo N, Moizumi S, Kitazawa S.

PLoS One. 2010 May 5;5(5):e10483. doi: 10.1371/journal.pone.0010483.

29.
30.

Noninvasive bioluminescence imaging of c-fos expression in the mouse barrel cortex.

Wada M, Watanabe S, Chung UI, Higo N, Taniguchi T, Kitazawa S.

Behav Brain Res. 2010 Mar 17;208(1):158-62. doi: 10.1016/j.bbr.2009.11.024. Epub 2009 Nov 30.

PMID:
19931567
31.

Increased expression of the growth-associated protein 43 gene in the sensorimotor cortex of the macaque monkey after lesioning the lateral corticospinal tract.

Higo N, Nishimura Y, Murata Y, Oishi T, Yoshino-Saito K, Takahashi M, Tsuboi F, Isa T.

J Comp Neurol. 2009 Oct 20;516(6):493-506. doi: 10.1002/cne.22121.

PMID:
19672995
32.

Expression of immediate-early genes reveals functional compartments within ocular dominance columns after brief monocular inactivation.

Takahata T, Higo N, Kaas JH, Yamamori T.

Proc Natl Acad Sci U S A. 2009 Jul 21;106(29):12151-5. doi: 10.1073/pnas.0905092106. Epub 2009 Jul 6.

33.

Chemical mapping of tulobuterol in transdermal tapes using microscopic laser Raman spectroscopy.

Sakamoto T, Matsubara T, Sasakura D, Takada Y, Fujimaki Y, Aida K, Miura T, Terahara T, Higo N, Kawanishi T, Hiyama Y.

Pharmazie. 2009 Mar;64(3):166-71.

PMID:
19348338
34.

Enriched expression of serotonin 1B and 2A receptor genes in macaque visual cortex and their bidirectional modulatory effects on neuronal responses.

Watakabe A, Komatsu Y, Sadakane O, Shimegi S, Takahata T, Higo N, Tochitani S, Hashikawa T, Naito T, Osaki H, Sakamoto H, Okamoto M, Ishikawa A, Hara S, Akasaki T, Sato H, Yamamori T.

Cereb Cortex. 2009 Aug;19(8):1915-28. doi: 10.1093/cercor/bhn219. Epub 2008 Dec 4.

35.

Expression of FOXP2 in the developing monkey forebrain: comparison with the expression of the genes FOXP1, PBX3, and MEIS2.

Takahashi K, Liu FC, Oishi T, Mori T, Higo N, Hayashi M, Hirokawa K, Takahashi H.

J Comp Neurol. 2008 Jul 10;509(2):180-9. doi: 10.1002/cne.21740.

PMID:
18461604
36.

Effects of motor training on the recovery of manual dexterity after primary motor cortex lesion in macaque monkeys.

Murata Y, Higo N, Oishi T, Yamashita A, Matsuda K, Hayashi M, Yamane S.

J Neurophysiol. 2008 Feb;99(2):773-86. Epub 2007 Dec 19.

37.

Difference in sensory dependence of occ1/Follistatin-related protein expression between macaques and mice.

Takahata T, Hashikawa T, Higo N, Tochitani S, Yamamori T.

J Chem Neuroanat. 2008 Jan;35(1):146-57. Epub 2007 Sep 16.

PMID:
17950574
38.

Expression of protein kinase-C substrate mRNA in the motor cortex of adult and infant macaque monkeys.

Higo N, Oishi T, Yamashita A, Murata Y, Matsuda K, Hayashi M.

Brain Res. 2007 Sep 26;1171:30-41. Epub 2007 Aug 8.

PMID:
17761152
39.

Differentially expressed genes among motor and prefrontal areas of macaque neocortex.

Sato A, Nishimura Y, Oishi T, Higo N, Murata Y, Onoe H, Saito K, Tsuboi F, Takahashi M, Isa T, Kojima T.

Biochem Biophys Res Commun. 2007 Oct 26;362(3):665-9. Epub 2007 Aug 20.

PMID:
17761142
40.

Cucurbitane-type triterpenoids from the fruits of Momordica charantia and their cancer chemopreventive effects.

Akihisa T, Higo N, Tokuda H, Ukiya M, Akazawa H, Tochigi Y, Kimura Y, Suzuki T, Nishino H.

J Nat Prod. 2007 Aug;70(8):1233-9. Epub 2007 Aug 9.

PMID:
17685651
41.

[Recent trend of transdermal drug delivery system development].

Higo N.

Yakugaku Zasshi. 2007 Apr;127(4):655-62. Review. Japanese.

42.

Expression of protein kinase C-substrate mRNAs in the basal ganglia of adult and infant macaque monkeys.

Higo N, Oishi T, Yamashita A, Murata Y, Matsuda K, Hayashi M.

J Comp Neurol. 2006 Dec 1;499(4):662-76.

PMID:
17029258
43.

Effect of electroporation and pH on the iontophoretic transdermal delivery of human insulin.

Tokumoto S, Higo N, Sugibayashi K.

Int J Pharm. 2006 Dec 1;326(1-2):13-9. Epub 2006 Jul 8.

PMID:
16920293
44.

Statistical parametric mapping of immunopositive cell density.

Wada M, Yoshimi K, Higo N, Ren YR, Mochizuki H, Mizuno Y, Kitazawa S.

Neurosci Res. 2006 Sep;56(1):96-102. Epub 2006 Jul 17.

PMID:
16846658
45.

Northern blot and in situ hybridization analyses for the neurogranin mRNA in the developing monkey cerebral cortex.

Higo N, Oishi T, Yamashita A, Murata Y, Matsuda K, Hayashi M.

Brain Res. 2006 Mar 17;1078(1):35-48. Epub 2006 Feb 23.

PMID:
16497282
46.

Developmental changes in the expression of growth-associated protein-43 mRNA in the monkey thalamus: northern blot and in situ hybridization studies.

Murata Y, Higo N, Oishi T, Yamashita A, Matsuda K, Hayashi M.

Neuroscience. 2005;136(2):497-507. Epub 2005 Oct 3.

PMID:
16203103
47.

Effect of electroporation on the electroosmosis across hairless mouse skin in vitro.

Tokumoto S, Mori K, Higo N, Sugibayashi K.

J Control Release. 2005 Jul 20;105(3):296-304.

PMID:
15894395
48.
49.

Cell type- and region-specific expression of neurogranin mRNA in the cerebral cortex of the macaque monkey.

Higo N, Oishi T, Yamashita A, Matsuda K, Hayashi M.

Cereb Cortex. 2004 Oct;14(10):1134-43. Epub 2004 Apr 27.

PMID:
15115741
50.

Association of verrucous skin lesions and skin ulcers on the feet in patients with diabetic neuropathy.

Sueki H, Furukawa N, Higo N, Akiyama M, Batchelor J, Iijima M.

Clin Exp Dermatol. 2004 May;29(3):247-53.

PMID:
15115503

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