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Items: 49

1.

A Systems Biology Approach to Understanding the Mechanisms of Action of an Alternative Anticancer Compound in Comparison to Cisplatin.

Wright EP, Padula MP, Higgins VJ, Aldrich-Wright JR, Coorssen JR.

Proteomes. 2014 Nov 10;2(4):501-526. doi: 10.3390/proteomes2040501.

2.

Transcriptomic insights into the molecular response of Saccharomyces cerevisiae to linoleic acid hydroperoxide.

O'Doherty PJ, Lyons V, Higgins VJ, Rogers PJ, Bailey TD, Wu MJ.

Free Radic Res. 2013 Dec;47(12):1054-65. doi: 10.3109/10715762.2013.849344. Epub 2013 Oct 21.

PMID:
24074273
3.

Superoxide radicals have a protective role during H2O2 stress.

Thorpe GW, Reodica M, Davies MJ, Heeren G, Jarolim S, Pillay B, Breitenbach M, Higgins VJ, Dawes IW.

Mol Biol Cell. 2013 Sep;24(18):2876-84. doi: 10.1091/mbc.E13-01-0052. Epub 2013 Jul 17.

4.

The Saccharomyces cerevisiae transcriptome as a mirror of phytochemical variation in complex extracts of Equisetum arvense from America, China, Europe and India.

Cook R, Hennell JR, Lee S, Khoo CS, Carles MC, Higgins VJ, Govindaraghavan S, Sucher NJ.

BMC Genomics. 2013 Jul 4;14:445. doi: 10.1186/1471-2164-14-445.

5.

Identification of the molecular mechanisms underlying the cytotoxic action of a potent platinum metallointercalator.

Wang S, Higgins VJ, Aldrich-Wright JR, Wu MJ.

J Chem Biol. 2012 Apr;5(2):51-61. doi: 10.1007/s12154-011-0070-x. Epub 2011 Dec 6.

6.

Comparative analyses of cytotoxicity and molecular mechanisms between platinum metallointercalators and cisplatin.

Wang S, Wu MJ, Higgins VJ, Aldrich-Wright JR.

Metallomics. 2012 Aug;4(9):950-9. doi: 10.1039/c2mt20102j.

PMID:
22814756
7.

Delineation of the molecular mechanism for disulfide stress-induced aluminium toxicity.

Wu MJ, Murphy PA, O'Doherty PJ, Mieruszynski S, Jones M, Kersaitis C, Rogers PJ, Bailey TD, Higgins VJ.

Biometals. 2012 Jun;25(3):553-61. doi: 10.1007/s10534-012-9534-x. Epub 2012 Mar 9.

PMID:
22403011
8.

Measuring hydrogen peroxide reduction using a robust, inexpensive, and sensitive method.

Hyland RA, Rogers PJ, Higgins VJ, Myers S, Coorssen JR.

J Chem Biol. 2012 Sep 2;5(4):143-50. doi: 10.1007/s12154-012-0083-0. eCollection 2012.

9.

Different reactive oxygen species lead to distinct changes of cellular metal ions in the eukaryotic model organism Saccharomyces cerevisiae.

Wu MJ, O'Doherty PJ, Murphy PA, Lyons V, Christophersen M, Rogers PJ, Bailey TD, Higgins VJ.

Int J Mol Sci. 2011;12(11):8119-32. doi: 10.3390/ijms12118119. Epub 2011 Nov 18.

10.

Effects of rehydration nutrients on H2S metabolism and formation of volatile sulfur compounds by the wine yeast VL3.

Winter G, Henschke PA, Higgins VJ, Ugliano M, Curtin CD.

AMB Express. 2011 Nov 2;1:36. doi: 10.1186/2191-0855-1-36.

11.

Managing and avoiding delay in operating theatres: a qualitative, observational study.

Higgins VJ, Bryant MJ, Villanueva EV, Kitto SC.

J Eval Clin Pract. 2013 Feb;19(1):162-6. doi: 10.1111/j.1365-2753.2011.01787.x. Epub 2011 Oct 26.

PMID:
22029715
12.

Identification of a protein with antioxidant activity that is important for the protection against beer ageing.

Wu MJ, Clarke FM, Rogers PJ, Young P, Sales N, O'Doherty PJ, Higgins VJ.

Int J Mol Sci. 2011;12(9):6089-103. doi: 10.3390/ijms12096089. Epub 2011 Sep 19.

13.

An antioxidant screening assay based on oxidant-induced growth arrest in Saccharomyces cerevisiae.

Wu MJ, O'Doherty PJ, Fernandez HR, Lyons V, Rogers PJ, Dawes IW, Higgins VJ.

FEMS Yeast Res. 2011 Jun;11(4):379-87. doi: 10.1111/j.1567-1364.2011.00726.x. Epub 2011 Mar 24.

14.

Zinc starvation induces a stress response in Saccharomyces cerevisiae that is mediated by the Msn2p and Msn4p transcriptional activators.

Gauci VJ, Beckhouse AG, Lyons V, Beh EJ, Rogers PJ, Dawes IW, Higgins VJ.

FEMS Yeast Res. 2009 Dec;9(8):1187-95. doi: 10.1111/j.1567-1364.2009.00557.x. Epub 2009 Jul 31.

15.

Essential role of one-carbon metabolism and Gcn4p and Bas1p transcriptional regulators during adaptation to anaerobic growth of Saccharomyces cerevisiae.

Tsoi BM, Beckhouse AG, Gelling CL, Raftery MJ, Chiu J, Tsoi AM, Lauterbach L, Rogers PJ, Higgins VJ, Dawes IW.

J Biol Chem. 2009 Apr 24;284(17):11205-15. doi: 10.1074/jbc.M809225200. Epub 2009 Feb 18.

16.

The adaptive response of anaerobically grown Saccharomyces cerevisiae to hydrogen peroxide is mediated by the Yap1 and Skn7 transcription factors.

Beckhouse AG, Grant CM, Rogers PJ, Dawes IW, Higgins VJ.

FEMS Yeast Res. 2008 Dec;8(8):1214-22. doi: 10.1111/j.1567-1364.2008.00439.x. Epub 2008 Sep 15.

17.

Adaptation to hydrogen peroxide in Saccharomyces cerevisiae: the role of NADPH-generating systems and the SKN7 transcription factor.

Ng CH, Tan SX, Perrone GG, Thorpe GW, Higgins VJ, Dawes IW.

Free Radic Biol Med. 2008 Mar 15;44(6):1131-45. doi: 10.1016/j.freeradbiomed.2007.12.008. Epub 2007 Dec 23.

PMID:
18206664
18.

Oxidant-induced cell-cycle delay in Saccharomyces cerevisiae: the involvement of the SWI6 transcription factor.

Fong CS, Temple MD, Alic N, Chiu J, Durchdewald M, Thorpe GW, Higgins VJ, Dawes IW.

FEMS Yeast Res. 2008 May;8(3):386-99. doi: 10.1111/j.1567-1364.2007.00349.x. Epub 2008 Jan 14.

19.

Novel platinum(II)-based anticancer complexes and molecular hosts as their drug delivery vehicles.

Wheate NJ, Taleb RI, Krause-Heuer AM, Cook RL, Wang S, Higgins VJ, Aldrich-Wright JR.

Dalton Trans. 2007 Nov 21;(43):5055-64. Epub 2007 Sep 27.

PMID:
17992290
20.

Encapsulation of platinum(II)-based DNA intercalators within cucurbit[6,7,8]urils.

Kemp S, Wheate NJ, Wang S, Collins JG, Ralph SF, Day AI, Higgins VJ, Aldrich-Wright JR.

J Biol Inorg Chem. 2007 Sep;12(7):969-79. Epub 2007 Jul 25.

PMID:
17653578
21.

Mechanism of selectivity of an angiogenesis inhibitor from screening a genome-wide set of Saccharomyces cerevisiae deletion strains.

Dilda PJ, Don AS, Tanabe KM, Higgins VJ, Allen JD, Dawes IW, Hogg PJ.

J Natl Cancer Inst. 2005 Oct 19;97(20):1539-47.

PMID:
16234568
22.

Nitric oxide has a regulatory effect in the germination of conidia of Colletotrichum coccodes.

Wang J, Higgins VJ.

Fungal Genet Biol. 2005 Apr;42(4):284-92.

PMID:
15749048
23.

Genome-wide transcriptional responses to a lipid hydroperoxide: adaptation occurs without induction of oxidant defenses.

Alic N, Felder T, Temple MD, Gloeckner C, Higgins VJ, Briza P, Dawes IW.

Free Radic Biol Med. 2004 Jul 1;37(1):23-35.

PMID:
15183192
24.

The role of the jasmonate response in plant susceptibility to diverse pathogens with a range of lifestyles.

Thaler JS, Owen B, Higgins VJ.

Plant Physiol. 2004 May;135(1):530-8. Epub 2004 May 7.

25.

Cells have distinct mechanisms to maintain protection against different reactive oxygen species: oxidative-stress-response genes.

Thorpe GW, Fong CS, Alic N, Higgins VJ, Dawes IW.

Proc Natl Acad Sci U S A. 2004 Apr 27;101(17):6564-9. Epub 2004 Apr 15.

26.
27.

Lipid hydroperoxides activate the mitogen-activated protein kinase Mpk1p in Saccharomyces cerevisiae.

Alic N, Higgins VJ, Pichova A, Breitenbach M, Dawes IW.

J Biol Chem. 2003 Oct 24;278(43):41849-55. Epub 2003 Aug 11.

28.
29.

The essential and ancillary role of glutathione in Saccharomyces cerevisiae analysed using a grande gsh1 disruptant strain.

Lee JC, Straffon MJ, Jang TY, Higgins VJ, Grant CM, Dawes IW.

FEMS Yeast Res. 2001 Apr;1(1):57-65.

30.

Molecular analysis of maltotriose transport and utilization by Saccharomyces cerevisiae.

Day RE, Rogers PJ, Dawes IW, Higgins VJ.

Appl Environ Microbiol. 2002 Nov;68(11):5326-35.

31.

Characterization of the putative maltose transporters encoded by YDL247w and YJR160c.

Day RE, Higgins VJ, Rogers PJ, Dawes IW.

Yeast. 2002 Sep 15;19(12):1015-27.

32.
33.

H2O2 plays different roles in determining penetration failure in three diverse plant-fungal interactions.

Mellersh DG, Foulds IV, Higgins VJ, Heath MC.

Plant J. 2002 Feb;29(3):257-68.

34.

Phenotypic analysis of gene deletant strains for sensitivity to oxidative stress.

Higgins VJ, Alic N, Thorpe GW, Breitenbach M, Larsson V, Dawes IW.

Yeast. 2002 Feb;19(3):203-14.

35.
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42.

Activation of Plant Plasma Membrane Ca2+-Permeable Channels by Race-Specific Fungal Elicitors.

Gelli A, Higgins VJ, Blumwald E.

Plant Physiol. 1997 Jan;113(1):269-279.

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48.

Degradation of alfalfa phytoalexin by Stemphylium botryosum.

Higgins VJ, Millar RL.

Phytopathology. 1969 Oct;59(10):1500-6. No abstract available.

PMID:
5392961
49.

Comparative abilities of Stemphylium botryosum and Helminthosporium turcicum to induce and degrade a phytoalexin from alfalfa.

Higgins VJ, Millar RL.

Phytopathology. 1969 Oct;59(10):1493-9. No abstract available.

PMID:
5392960

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