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Items: 1 to 50 of 189

1.

In vitro and in vivo Virulence Potential of the Emergent Species of the Acinetobacter baumannii (Ab) Group.

Cosgaya C, Ratia C, Marí-Almirall M, Rubio L, Higgins PG, Seifert H, Roca I, Vila J.

Front Microbiol. 2019 Oct 24;10:2429. doi: 10.3389/fmicb.2019.02429. eCollection 2019.

2.

In-vitro activity of the novel fluorocycline TP-6076 against carbapenem-resistant Acinetobacter baumannii.

Seifert H, Stefanik D, Olesky M, Higgins PG.

Int J Antimicrob Agents. 2019 Oct 26. pii: S0924-8579(19)30290-0. doi: 10.1016/j.ijantimicag.2019.10.010. [Epub ahead of print]

PMID:
31669740
3.

Genetic Features of Antarctic Acinetobacter radioresistens Strain A154 Harboring Multiple Antibiotic-Resistance Genes.

Opazo-Capurro A, Higgins PG, Wille J, Seifert H, Cigarroa C, González-Muñoz P, Quezada-Aguiluz M, Domínguez-Yévenes M, Bello-Toledo H, Vergara L, González-Rocha G.

Front Cell Infect Microbiol. 2019 Sep 13;9:328. doi: 10.3389/fcimb.2019.00328. eCollection 2019.

4.

Restoring the activity of the antibiotic aztreonam using the polyphenol epigallocatechin gallate (EGCG) against multidrug-resistant clinical isolates of Pseudomonas aeruginosa.

Betts JW, Hornsey M, Higgins PG, Lucassen K, Wille J, Salguero FJ, Seifert H, La Ragione RM.

J Med Microbiol. 2019 Oct;68(10):1552-1559. doi: 10.1099/jmm.0.001060.

PMID:
31419210
5.

Controlling intestinal colonization of high-risk haematology patients with ESBL-producing Enterobacteriaceae: a randomized, placebo-controlled, multicentre, Phase II trial (CLEAR).

Dimitriou V, Biehl LM, Hamprecht A, Vogel W, Dörfel D, Peter S, Schafhausen P, Rohde H, von Lilienfeld-Toal M, Klassert TE, Slickers P, Ehricht R, Slevogt H, Christ H, Hellmich M, Farowski F, Tsakmaklis A, Higgins PG, Seifert H, Vehreschild MJGT.

J Antimicrob Chemother. 2019 Jul 1;74(7):2065-2074. doi: 10.1093/jac/dkz124.

PMID:
31220256
6.

Generation and selection of antibodies for a novel immunochromatographic lateral flow test to rapidly identify OXA-23-like-mediated carbapenem resistance in Acinetobacter baumannii.

Mertins S, Higgins PG, Rodríguez MG, Borlon C, Gilleman Q, Mertens P, Seifert H, Krönke M, Klimka A.

J Med Microbiol. 2019 Jul;68(7):1021-1032. doi: 10.1099/jmm.0.001015. Epub 2019 Jun 12.

PMID:
31188094
7.

In vitro activity of mecillinam and nitroxoline against Neisseria gonorrhoeae - re-purposing old antibiotics in the multi-drug resistance era.

Fuchs F, Wille J, Hamprecht A, Parcina M, Lehmann C, Schwarze-Zander C, Seifert H, Higgins PG.

J Med Microbiol. 2019 Jul;68(7):991-995. doi: 10.1099/jmm.0.001014. Epub 2019 Jun 4.

PMID:
31162022
8.

Phenotypic and Genotypic Characterization of Acinetobacter spp. Panel Strains: A Cornerstone to Facilitate Antimicrobial Development.

D'Souza R, Pinto NA, Phuong NL, Higgins PG, Vu TN, Byun JH, Cho YL, Choi JR, Yong D.

Front Microbiol. 2019 Mar 26;10:559. doi: 10.3389/fmicb.2019.00559. eCollection 2019.

9.

Acinetobacter baumannii analysis by core genome multi-locus sequence typing in two hospitals in Bolivia: endemicity of international clone 7 isolates (CC25).

Cerezales M, Xanthopoulou K, Wille J, Bustamante Z, Seifert H, Gallego L, Higgins PG.

Int J Antimicrob Agents. 2019 Jun;53(6):844-849. doi: 10.1016/j.ijantimicag.2019.03.019. Epub 2019 Mar 27.

PMID:
30928684
10.

Seasonal Occurrence and Carbapenem Susceptibility of Bovine Acinetobacter baumannii in Germany.

Klotz P, Higgins PG, Schaubmar AR, Failing K, Leidner U, Seifert H, Scheufen S, Semmler T, Ewers C.

Front Microbiol. 2019 Feb 22;10:272. doi: 10.3389/fmicb.2019.00272. eCollection 2019.

11.

Identification of the novel class D β-lactamase OXA-679 involved in carbapenem resistance in Acinetobacter calcoaceticus.

Tietgen M, Kramer JS, Brunst S, Djahanschiri B, Wohra S, Higgins PG, Weidensdorfer M, Riedel-Christ S, Pos KM, Gonzaga A, Steglich M, Nübel U, Ebersberger I, Proschak E, Göttig S.

J Antimicrob Chemother. 2019 Jun 1;74(6):1494-1502. doi: 10.1093/jac/dkz080.

PMID:
30844059
12.

Potential biomarkers to predict outcome of faecal microbiota transfer for recurrent Clostridioides difficile infection.

Farowski F, Solbach P, Tsakmaklis A, Brodesser S, Cruz Aguilar MR, Cornely OA, Dettmer K, Higgins PG, Suerbaum S, Jazmati N, Oefner PJ, Vehreschild MJGT; German Clinical Microbiome Study Group (GCMSG).

Dig Liver Dis. 2019 Jul;51(7):944-951. doi: 10.1016/j.dld.2019.01.012. Epub 2019 Jan 26.

PMID:
30770201
13.

Epidemiological Typing of Serratia marcescens Isolates by Whole-Genome Multilocus Sequence Typing.

Rossen JWA, Dombrecht J, Vanfleteren D, De Bruyne K, van Belkum A, Rosema S, Lokate M, Bathoorn E, Reuter S, Grundmann H, Ertel J, Higgins PG, Seifert H.

J Clin Microbiol. 2019 Mar 28;57(4). pii: e01652-18. doi: 10.1128/JCM.01652-18. Print 2019 Apr.

14.

Investigation of Novel pmrB and eptA Mutations in Isogenic Acinetobacter baumannii Isolates Associated with Colistin Resistance and Increased Virulence In Vivo.

Gerson S, Betts JW, Lucaßen K, Nodari CS, Wille J, Josten M, Göttig S, Nowak J, Stefanik D, Roca I, Vila J, Cisneros JM, La Ragione RM, Seifert H, Higgins PG.

Antimicrob Agents Chemother. 2019 Feb 26;63(3). pii: e01586-18. doi: 10.1128/AAC.01586-18. Print 2019 Mar.

15.

Assessment of urinary 3-indoxyl sulfate as a marker for gut microbiota diversity and abundance of Clostridiales.

Farowski F, Els G, Tsakmaklis A, Higgins PG, Kahlert CR, Stein-Thoeringer CK, Bobardt JS, Dettmer-Wilde K, Oefner PJ, Vehreschild JJ, Vehreschild MJGT.

Gut Microbes. 2019;10(2):133-141. doi: 10.1080/19490976.2018.1502536. Epub 2018 Aug 17.

16.

Identification of Acinetobacter seifertii isolated from Bolivian hospitals.

Cerezales M, Xanthopoulou K, Ertel J, Nemec A, Bustamante Z, Seifert H, Gallego L, Higgins PG.

J Med Microbiol. 2018 Jun;67(6):834-837. doi: 10.1099/jmm.0.000751. Epub 2018 May 8.

PMID:
29737964
17.

Characterization of Acinetobacter baumannii from water and sludge line of secondary wastewater treatment plant.

Higgins PG, Hrenovic J, Seifert H, Dekic S.

Water Res. 2018 Sep 1;140:261-267. doi: 10.1016/j.watres.2018.04.057. Epub 2018 Apr 26.

PMID:
29723815
18.

Diversity of mutations in regulatory genes of resistance-nodulation-cell division efflux pumps in association with tigecycline resistance in Acinetobacter baumannii.

Gerson S, Nowak J, Zander E, Ertel J, Wen Y, Krut O, Seifert H, Higgins PG.

J Antimicrob Chemother. 2018 Jun 1;73(6):1501-1508. doi: 10.1093/jac/dky083.

PMID:
29554339
19.

High Prevalence of Extensively Drug-resistant Acinetobacter baumannii at a Children Hospital in Bolivia.

Cerezales M, Ocampo-Sosa AA, Álvarez Montes L, Díaz Ríos C, Bustamante Z, Santos J, Martínez-Martínez L, Higgins PG, Gallego L.

Pediatr Infect Dis J. 2018 Nov;37(11):1118-1123. doi: 10.1097/INF.0000000000001962.

PMID:
29474260
20.

Complete Genome Sequencing of Acinetobacter sp. Strain LoGeW2-3, Isolated from the Pellet of a White Stork, Reveals a Novel Class D Beta-Lactamase Gene.

Blaschke U, Skiebe E, Kaatz M, Higgins PG, Pfeifer Y, Wilharm G.

Genome Announc. 2018 Jan 11;6(2). pii: e01405-17. doi: 10.1128/genomeA.01405-17.

21.

High incidence of pandrug-resistant Acinetobacter baumannii isolates collected from patients with ventilator-associated pneumonia in Greece, Italy and Spain as part of the MagicBullet clinical trial.

Nowak J, Zander E, Stefanik D, Higgins PG, Roca I, Vila J, McConnell MJ, Cisneros JM, Seifert H; MagicBullet Working Group WP4.

J Antimicrob Chemother. 2017 Dec 1;72(12):3277-3282. doi: 10.1093/jac/dkx322.

22.

Mechanistic insight into how multidrug resistant Acinetobacter baumannii response regulator AdeR recognizes an intercistronic region.

Wen Y, Ouyang Z, Yu Y, Zhou X, Pei Y, Devreese B, Higgins PG, Zheng F.

Nucleic Acids Res. 2017 Sep 19;45(16):9773-9787. doi: 10.1093/nar/gkx624.

23.

Relatedness of wildlife and livestock avian isolates of the nosocomial pathogen Acinetobacter baumannii to lineages spread in hospitals worldwide.

Wilharm G, Skiebe E, Higgins PG, Poppel MT, Blaschke U, Leser S, Heider C, Heindorf M, Brauner P, Jäckel U, Böhland K, Cuny C, Łopińska A, Kaminski P, Kasprzak M, Bochenski M, Ciebiera O, Tobółka M, Żołnierowicz KM, Siekiera J, Seifert H, Gagné S, Salcedo SP, Kaatz M, Layer F, Bender JK, Fuchs S, Semmler T, Pfeifer Y, Jerzak L.

Environ Microbiol. 2017 Oct;19(10):4349-4364. doi: 10.1111/1462-2920.13931. Epub 2017 Oct 9.

PMID:
28925528
24.

Nosocomial Outbreak of Extensively Drug-Resistant Acinetobacter baumannii Isolates Containing blaOXA-237 Carried on a Plasmid.

Hujer AM, Higgins PG, Rudin SD, Buser GL, Marshall SH, Xanthopoulou K, Seifert H, Rojas LJ, Domitrovic TN, Cassidy PM, Cunningham MC, Vega R, Furuno JP, Pfeiffer CD, Beldavs ZG, Wright MS, Jacobs MR, Adams MD, Bonomo RA.

Antimicrob Agents Chemother. 2017 Oct 24;61(11). pii: e00797-17. doi: 10.1128/AAC.00797-17. Print 2017 Nov.

25.

Failure to Communicate: Transmission of Extensively Drug-Resistant bla OXA-237-Containing Acinetobacter baumannii-Multiple Facilities in Oregon, 2012-2014.

Buser GL, Cassidy PM, Cunningham MC, Rudin S, Hujer AM, Vega R, Furuno JP, Marshall SH, Higgins PG, Jacobs MR, Wright MS, Adams MD, Bonomo RA, Pfeiffer CD, Beldavs ZG.

Infect Control Hosp Epidemiol. 2017 Nov;38(11):1335-1341. doi: 10.1017/ice.2017.189. Epub 2017 Sep 5.

26.

Emergence of different Acinetobacter baumannii clones in a Croatian hospital and correlation with antibiotic susceptibility.

Ladavac R, Bedenić B, Vranić-Ladavac M, Barišić N, Karčić N, Pompe K, Ferenčić A, Stojanović A, Seifert H, Katić S, Higgins PG.

J Glob Antimicrob Resist. 2017 Sep;10:213-218. doi: 10.1016/j.jgar.2017.07.001. Epub 2017 Jul 19.

PMID:
28735048
27.

In-vitro activity of the novel fluorocycline eravacycline against carbapenem non-susceptible Acinetobacter baumannii.

Seifert H, Stefanik D, Sutcliffe JA, Higgins PG.

Int J Antimicrob Agents. 2018 Jan;51(1):62-64. doi: 10.1016/j.ijantimicag.2017.06.022. Epub 2017 Jul 11.

PMID:
28705668
28.

Development and evaluation of a core genome multilocus typing scheme for whole-genome sequence-based typing of Acinetobacter baumannii.

Higgins PG, Prior K, Harmsen D, Seifert H.

PLoS One. 2017 Jun 8;12(6):e0179228. doi: 10.1371/journal.pone.0179228. eCollection 2017.

29.

Correction for Evans et al., "Informing Antibiotic Treatment Decisions: Evaluating Rapid Molecular Diagnostics To Identify Susceptibility and Resistance to Carbapenems against Acinetobacter spp. in PRIMERS III".

Evans SR, Hujer AM, Jiang H, Hill CB, Hujer KM, Mediavilla JR, Manca C, Tran TTT, Domitrovic TN, Higgins PG, Seifert H, Kreiswirth BN, Patel R, Jacobs MR, Chen L, Sampath R, Hall T, Marzan C, Fowler VG Jr, Chambers HF, Bonomo RA.

J Clin Microbiol. 2017 Jun;55(6):1970. doi: 10.1128/JCM.00525-17. No abstract available.

30.

First Report of the Carbapenemase Gene blaOXA-499 in Acinetobacter pittii.

D'Souza R, Pinto NA, Higgins PG, Hwang I, Yong D, Choi J, Lee K, Chong Y.

Antimicrob Agents Chemother. 2017 Apr 24;61(5). pii: e02676-16. doi: 10.1128/AAC.02676-16. Print 2017 May.

31.

MALDI-TOF/MS identification of species from the Acinetobacter baumannii (Ab) group revisited: inclusion of the novel A. seifertii and A. dijkshoorniae species.

Marí-Almirall M, Cosgaya C, Higgins PG, Van Assche A, Telli M, Huys G, Lievens B, Seifert H, Dijkshoorn L, Roca I, Vila J.

Clin Microbiol Infect. 2017 Mar;23(3):210.e1-210.e9. doi: 10.1016/j.cmi.2016.11.020. Epub 2016 Dec 3.

32.

Informing Antibiotic Treatment Decisions: Evaluating Rapid Molecular Diagnostics To Identify Susceptibility and Resistance to Carbapenems against Acinetobacter spp. in PRIMERS III.

Evans SR, Hujer AM, Jiang H, Hill CB, Hujer KM, Mediavilla JR, Manca C, Tran TT, Domitrovic TN, Higgins PG, Seifert H, Kreiswirth BN, Patel R, Jacobs MR, Chen L, Sampath R, Hall T, Marzan C, Fowler VG Jr, Chambers HF, Bonomo RA.

J Clin Microbiol. 2016 Dec 28;55(1):134-144. doi: 10.1128/JCM.01524-16. Print 2017 Jan. Erratum in: J Clin Microbiol. 2017 Jun;55(6):1970.

33.

Draft Genome Sequences of Nine Clinical Isolates of Vancomycin-Resistant Enterococci.

Higgins PG, Koehler D, Chan JZ, Cornely OA, Fätkenheuer G, Gillis M, Pallen MJ, Tien J, Seifert H, Vehreschild MJ, Millard AD.

Genome Announc. 2016 Aug 18;4(4). pii: e00803-16. doi: 10.1128/genomeA.00803-16.

34.

Acinetobacter dijkshoorniae sp. nov., a member of the Acinetobacter calcoaceticus-Acinetobacter baumannii complex mainly recovered from clinical samples in different countries.

Cosgaya C, Marí-Almirall M, Van Assche A, Fernández-Orth D, Mosqueda N, Telli M, Huys G, Higgins PG, Seifert H, Lievens B, Roca I, Vila J.

Int J Syst Evol Microbiol. 2016 Oct;66(10):4105-4111. doi: 10.1099/ijsem.0.001318. Epub 2016 Jul 15.

PMID:
27432448
35.

Draft Genome Sequences of 11 Clinical Isolates of Acinetobacter baumannii.

Higgins PG, Chan JZ, Seifert H, Pallen MJ, Millard AD.

Genome Announc. 2016 Apr 14;4(2). pii: e00269-16. doi: 10.1128/genomeA.00269-16.

36.

Head-to-Head Comparison of Two Multi-Locus Sequence Typing (MLST) Schemes for Characterization of Acinetobacter baumannii Outbreak and Sporadic Isolates.

Tomaschek F, Higgins PG, Stefanik D, Wisplinghoff H, Seifert H.

PLoS One. 2016 Apr 12;11(4):e0153014. doi: 10.1371/journal.pone.0153014. eCollection 2016.

37.

Effects of Saline, an Ambient Acidic Environment, and Sodium Salicylate on OXA-Mediated Carbapenem Resistance in Acinetobacter baumannii.

Zander E, Seifert H, Higgins PG.

Antimicrob Agents Chemother. 2016 May 23;60(6):3415-8. doi: 10.1128/AAC.03010-15. Print 2016 Jun.

38.

Carbapenem-resistant Acinetobacter baumannii ST78 with OXA-72 carbapenemase and ESBL gene blaCTX-M-115.

Pfeifer Y, Hunfeld KP, Borgmann S, Maneg D, Blobner W, Werner G, Higgins PG.

J Antimicrob Chemother. 2016 May;71(5):1426-8. doi: 10.1093/jac/dkv462. Epub 2016 Jan 17. No abstract available.

PMID:
26782774
39.

Outbreak of carbapenem-resistant Acinetobacter baumannii in the intensive care unit: a multi-level strategic management approach.

Molter G, Seifert H, Mandraka F, Kasper G, Weidmann B, Hornei B, Öhler M, Schwimmbeck P, Kröschel P, Higgins PG, Reuter S.

J Hosp Infect. 2016 Feb;92(2):194-8. doi: 10.1016/j.jhin.2015.11.007. Epub 2015 Nov 22.

PMID:
26778130
40.

Prevalence of hypermutators among clinical Acinetobacter baumannii isolates.

Komp Lindgren P, Higgins PG, Seifert H, Cars O.

J Antimicrob Chemother. 2016 Mar;71(3):661-5. doi: 10.1093/jac/dkv378. Epub 2015 Dec 9.

41.

The Asp20-to-Asn Substitution in the Response Regulator AdeR Leads to Enhanced Efflux Activity of AdeB in Acinetobacter baumannii.

Nowak J, Schneiders T, Seifert H, Higgins PG.

Antimicrob Agents Chemother. 2015 Dec 7;60(2):1085-90. doi: 10.1128/AAC.02413-15. Print 2016 Feb.

42.

Prevalence of eight resistance-nodulation-division efflux pump genes in epidemiologically characterized Acinetobacter baumannii of worldwide origin.

Nowak J, Seifert H, Higgins PG.

J Med Microbiol. 2015 Jun;64(6):630-5. doi: 10.1099/jmm.0.000069. Epub 2015 Apr 14.

PMID:
25873581
43.

Acinetobacter seifertii sp. nov., a member of the Acinetobacter calcoaceticus-Acinetobacter baumannii complex isolated from human clinical specimens.

Nemec A, Krizova L, Maixnerova M, Sedo O, Brisse S, Higgins PG.

Int J Syst Evol Microbiol. 2015 Mar;65(Pt 3):934-42. doi: 10.1099/ijs.0.000043. Epub 2015 Jan 6.

PMID:
25563912
44.

Amino acid alterations in fibronectin binding protein A (FnBPA) and bacterial genotype are associated with cardiac device related infection in Staphylococcus aureus bacteraemia.

Hos NJ, Rieg S, Kern WV, Jonas D, Fowler VG, Higgins PG, Seifert H, Kaasch AJ.

J Infect. 2015 Feb;70(2):153-9. doi: 10.1016/j.jinf.2014.09.005. Epub 2014 Sep 22.

PMID:
25246358
45.

Detection of pan drug-resistant Acinetobacter baumannii in Germany.

Göttig S, Gruber TM, Higgins PG, Wachsmuth M, Seifert H, Kempf VA.

J Antimicrob Chemother. 2014 Sep;69(9):2578-9. doi: 10.1093/jac/dku170. Epub 2014 May 15. No abstract available.

PMID:
24833751
46.

Worldwide dissemination of acquired carbapenem-hydrolysing class D β-lactamases in Acinetobacter spp. other than Acinetobacter baumannii.

Zander E, Fernández-González A, Schleicher X, Dammhayn C, Kamolvit W, Seifert H, Higgins PG.

Int J Antimicrob Agents. 2014 Apr;43(4):375-7. doi: 10.1016/j.ijantimicag.2014.01.012. Epub 2014 Feb 12.

PMID:
24612983
47.

Characterization of blaOXA-143 variants in Acinetobacter baumannii and Acinetobacter pittii.

Zander E, Bonnin RA, Seifert H, Higgins PG.

Antimicrob Agents Chemother. 2014 May;58(5):2704-8. doi: 10.1128/AAC.02618-13. Epub 2014 Feb 24.

48.

Multiplex PCR to detect the genes encoding naturally occurring oxacillinases in Acinetobacter spp.

Kamolvit W, Higgins PG, Paterson DL, Seifert H.

J Antimicrob Chemother. 2014 Apr;69(4):959-63. doi: 10.1093/jac/dkt480. Epub 2013 Nov 27.

PMID:
24288029
49.

Molecular epidemiology characterization of OXA-23 carbapenemase-producing Acinetobacter baumannii isolated from 8 Brazilian hospitals using repetitive sequence-based PCR.

Cieslinski JM, Arend L, Tuon FF, Silva EP, Ekermann RG, Dalla-Costa LM, Higgins PG, Seifert H, Pilonetto M.

Diagn Microbiol Infect Dis. 2013 Dec;77(4):337-40. doi: 10.1016/j.diagmicrobio.2013.07.018. Epub 2013 Sep 24.

PMID:
24074766
50.

Insertion sequence IS18 mediates overexpression of blaOXA-257 in a carbapenem-resistant Acinetobacter bereziniae isolate.

Zander E, Seifert H, Higgins PG.

J Antimicrob Chemother. 2014 Jan;69(1):270-1. doi: 10.1093/jac/dkt313. Epub 2013 Aug 9. No abstract available.

PMID:
23934740

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