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Items: 1 to 50 of 807

1.

Delineating a role for the Mitochondrial Permeability Transition Pore in Diabetic Kidney Disease by targeting Cyclophilin D.

Lindblom RSJ, Higgins GC, Nguyen TV, Arnstein M, Henstridge DC, Granata C, Snelson M, Thallas-Bonke V, Cooper ME, Forbes JM, Coughlan MT.

Clin Sci (Lond). 2020 Jan 16. pii: CS20190787. doi: 10.1042/CS20190787. [Epub ahead of print]

PMID:
31943002
2.

Respiratory Viruses Cause Late Morbidity in Recipients of Hematopoietic Stem Cell Transplantation: Respiratory viruses causes late morbidity post-HSCT.

Marinelli T, Wee LYA, Rowe E, Chhetri R, Friel O, Higgins G, Bardy P, Singhal D, Pradhan A, Crawford L, Hiwase DK.

Biol Blood Marrow Transplant. 2019 Dec 19. pii: S1083-8791(19)31653-2. doi: 10.1016/j.bbmt.2019.12.724. [Epub ahead of print]

PMID:
31866345
3.

Early Single-Dose Treatment with Exosomes Provides Neuroprotection and Improves Blood-Brain Barrier Integrity in Swine Model of Traumatic Brain Injury and Hemorrhagic Shock.

Williams AM, Bhatti UF, Brown JF, Biesterveld BE, Kathawate RG, Graham NJ, Chtraklin K, Siddiqui AZ, Dekker SE, Andjelkovic A, Higgins GA, Buller B, Alam HB.

J Trauma Acute Care Surg. 2019 Dec 5. doi: 10.1097/TA.0000000000002563. [Epub ahead of print]

PMID:
31804413
4.

Pseudomonas aeruginosa PA5oct Jumbo Phage Impacts Planktonic and Biofilm Population and Reduces Its Host Virulence.

Olszak T, Danis-Wlodarczyk K, Arabski M, Gula G, Maciejewska B, Wasik S, Lood C, Higgins G, Harvey BJ, Lavigne R, Drulis-Kawa Z.

Viruses. 2019 Nov 23;11(12). pii: E1089. doi: 10.3390/v11121089.

5.

The Effects of Child and Adult Victimization on Psychological Distress: A Mediated Structural Equation Modeling Analysis.

Dishon-Brown A, Golder S, Renn T, Logan TK, Higgins GE.

Violence Against Women. 2019 Nov 22:1077801219885183. doi: 10.1177/1077801219885183. [Epub ahead of print]

PMID:
31752623
6.

Highly Polarizable Rydberg Ion in a Paul Trap.

Higgins G, Pokorny F, Zhang C, Hennrich M.

Phys Rev Lett. 2019 Oct 11;123(15):153602. doi: 10.1103/PhysRevLett.123.153602.

PMID:
31702307
7.

The introduction of plastic and reconstructive surgery to the University of Glasgow undergraduate medical core curriculum.

Higgins G, Thomson SE.

Postgrad Med J. 2019 Nov 1. pii: postgradmedj-2019-137046. doi: 10.1136/postgradmedj-2019-137046. [Epub ahead of print]

PMID:
31676592
8.

The Mitochondria-Targeted Methylglyoxal Sequestering Compound, MitoGamide, Is Cardioprotective in the Diabetic Heart.

Tate M, Higgins GC, De Blasio MJ, Lindblom R, Prakoso D, Deo M, Kiriazis H, Park M, Baeza-Garza CD, Caldwell ST, Hartley RC, Krieg T, Murphy MP, Coughlan MT, Ritchie RH.

Cardiovasc Drugs Ther. 2019 Dec 13. doi: 10.1007/s10557-019-06914-9. [Epub ahead of print]

PMID:
31654171
9.

Lorcaserin: A review of its preclinical and clinical pharmacology and therapeutic potential.

Higgins GA, Fletcher PJ, Shanahan WR.

Pharmacol Ther. 2020 Jan;205:107417. doi: 10.1016/j.pharmthera.2019.107417. Epub 2019 Oct 16. Review.

PMID:
31629010
10.

Initial Results from a Pilot Comparative Effectiveness Study of Three Methotrexate-Based Consensus Treatment Plans for Juvenile Localized Scleroderma.

Li SC, Torok KS, Rabinovich CE, Dedeoglu F, Becker ML, Ferguson PJ, Hong SD, Ibarra MF, Stewart K, Pope E, Higgins GC, Laxer RM, Mason T 2nd, Fuhlbrigge RC, Andrews T; CARRA Registry Investigators .

J Rheumatol. 2019 Oct 15. pii: jrheum.190311. doi: 10.3899/jrheum.190311. [Epub ahead of print]

PMID:
31615917
11.

Druggable Transcriptional Networks in the Human Neurogenic Epigenome.

Higgins GA, Williams AM, Ade AS, Alam HB, Athey BD.

Pharmacol Rev. 2019 Oct;71(4):520-538. doi: 10.1124/pr.119.017681. Review.

PMID:
31530573
12.

Intense interseasonal influenza outbreaks, Australia, 2018/19.

Barr IG, Deng YM, Grau ML, Han AX, Gilmour R, Irwin M, Markey P, Freeman K, Higgins G, Turra M, Komadina N, Peck H, Booy R, Maurer-Stroh S, Dhanasekaran V, Sullivan S.

Euro Surveill. 2019 Aug;24(33). doi: 10.2807/1560-7917.ES.2019.24.33.1900421. Erratum in: Euro Surveill. 2019 Aug;24(34):.

13.

Reply to 'The use of buparlisib as a radiosensitiser: What about toxicity?'

McGowan DR, Skwarski M, Higgins GS.

Eur J Cancer. 2019 Sep;119:196-197. doi: 10.1016/j.ejca.2019.07.013. Epub 2019 Aug 16. No abstract available.

PMID:
31427118
14.

The Influence of Sport Participation on African American Youth Binge Drinking.

Nicholson J, Higgins GE.

Subst Use Misuse. 2019;54(14):2328-2337. doi: 10.1080/10826084.2019.1648513. Epub 2019 Aug 9.

PMID:
31398074
15.

Developing comparative effectiveness studies for a rare, understudied pediatric disease: lessons learned from the CARRA juvenile localized scleroderma consensus treatment plan pilot study.

Li SC, Fuhlbrigge RC, Laxer RM, Pope E, Ibarra MF, Stewart K, Mason T 2nd, Becker ML, Hong S, Dedeoglu F, Torok KS, Rabinovich CE, Ferguson PJ, Punaro M, Feldman BM, Andrews T, Higgins GC; CARRA Registry Investigators.

Pediatr Rheumatol Online J. 2019 Jul 15;17(1):43. doi: 10.1186/s12969-019-0350-5.

16.

Increased EZH2 expression in prostate cancer is associated with metastatic recurrence following external beam radiotherapy.

Wu X, Scott H, Carlsson SV, Sjoberg DD, Cerundolo L, Lilja H, Prevo R, Rieunier G, Macaulay V, Higgins GS, Verrill CL, Lamb AD, Cunliffe VT, Bountra C, Hamdy FC, Bryant RJ.

Prostate. 2019 Jul;79(10):1079-1089. doi: 10.1002/pros.23817. Epub 2019 May 18.

17.

Evaluation of Selective 5-HT2C Agonists in Acute Seizure Models.

Silenieks LB, Carroll NK, Van Niekerk A, Van Niekerk E, Taylor C, Upton N, Higgins GA.

ACS Chem Neurosci. 2019 Jul 17;10(7):3284-3295. doi: 10.1021/acschemneuro.8b00739. Epub 2019 May 13.

PMID:
31082204
18.

Buparlisib with thoracic radiotherapy and its effect on tumour hypoxia: A phase I study in patients with advanced non-small cell lung carcinoma.

McGowan DR, Skwarski M, Bradley KM, Campo L, Fenwick JD, Gleeson FV, Green M, Horne A, Maughan TS, McCole MG, Mohammed S, Muschel RJ, Ng SM, Panakis N, Prevo R, Strauss VY, Stuart R, Tacconi EMC, Vallis KA, McKenna WG, Macpherson RE, Higgins GS.

Eur J Cancer. 2019 May;113:87-95. doi: 10.1016/j.ejca.2019.03.015. Epub 2019 Apr 13.

19.

Effective nebulization of interferon-γ using a novel vibrating mesh.

Sweeney L, McCloskey AP, Higgins G, Ramsey JM, Cryan SA, MacLoughlin R.

Respir Res. 2019 Apr 3;20(1):66. doi: 10.1186/s12931-019-1030-1.

20.

Prevalence and Correlates of Disability Among a Sample of Victimized Women on Probation and Parole.

Smith KE, Bunting AM, Golder S, Hall MT, Higgins GE, Logan TK.

J Correct Health Care. 2019 Apr;25(2):143-161. doi: 10.1177/1078345819833387. Epub 2019 Mar 13.

PMID:
30866703
21.

Tumor pH and Protein Concentration Contribute to the Signal of Amide Proton Transfer Magnetic Resonance Imaging.

Ray KJ, Simard MA, Larkin JR, Coates J, Kinchesh P, Smart SC, Higgins GS, Chappell MA, Sibson NR.

Cancer Res. 2019 Apr 1;79(7):1343-1352. doi: 10.1158/0008-5472.CAN-18-2168. Epub 2019 Jan 24.

22.

A life course perspective of victimization, child welfare involvement, cumulative stress and mental health for mothers on probation and parole.

Fedock G, Garthe RC, Sarantakos S, Golder S, Higgins GE, Logan TK.

Child Abuse Negl. 2018 Dec;86:235-246. doi: 10.1016/j.chiabu.2018.10.007. Epub 2018 Oct 26.

PMID:
30388707
23.

Publisher Correction: 3D Shape Modeling for Cell Nuclear Morphological Analysis and Classification.

Kalinin AA, Allyn-Feuer A, Ade A, Fon GV, Meixner W, Dilworth D, Husain SS, de Wet JR, Higgins GA, Zheng G, Creekmore A, Wiley JW, Verdone JE, Veltri RW, Pienta KJ, Coffey DS, Athey BD, Dinov ID.

Sci Rep. 2018 Oct 26;8(1):16142. doi: 10.1038/s41598-018-33574-w.

24.

[18F]FE-OTS964: a Small Molecule Targeting TOPK for In Vivo PET Imaging in a Glioblastoma Xenograft Model.

Pirovano G, Roberts S, Brand C, Donabedian PL, Mason C, de Souza PD, Higgins GS, Reiner T.

Mol Imaging Biol. 2019 Aug;21(4):705-712. doi: 10.1007/s11307-018-1288-6.

PMID:
30357568
25.

T-LAK cell-originated protein kinase (TOPK): an emerging target for cancer-specific therapeutics.

Herbert KJ, Ashton TM, Prevo R, Pirovano G, Higgins GS.

Cell Death Dis. 2018 Oct 24;9(11):1089. doi: 10.1038/s41419-018-1131-7. Review.

26.

Novel KV7 ion channel openers for the treatment of epilepsy and implications for detrusor tissue contraction.

Seefeld MA, Lin H, Holenz J, Downie D, Donovan B, Fu T, Pasikanti K, Zhen W, Cato M, Chaudhary KW, Brady P, Bakshi T, Morrow D, Rajagopal S, Samanta SK, Madhyastha N, Kuppusamy BM, Dougherty RW, Bhamidipati R, Mohd Z, Higgins GA, Chapman M, Rouget C, Lluel P, Matsuoka Y.

Bioorg Med Chem Lett. 2018 Dec 15;28(23-24):3793-3797. doi: 10.1016/j.bmcl.2018.09.036. Epub 2018 Sep 29.

PMID:
30327146
27.

CIZ1-F, an alternatively spliced variant of the DNA replication protein CIZ1 with distinct expression and localisation, is overrepresented in early stage common solid tumours.

Swarts DRA, Stewart ER, Higgins GS, Coverley D.

Cell Cycle. 2018;17(18):2268-2283. doi: 10.1080/15384101.2018.1526600. Epub 2018 Oct 6.

28.

Clinical Features and Laboratory Findings of Travelers Returning to South Australia with Dengue Virus Infection.

Quinn EJ, Cheong AH, Calvert JK, Higgins G, Hahesy T, Gordon DL, Carr JM.

Trop Med Infect Dis. 2018 Jan 7;3(1). pii: E6. doi: 10.3390/tropicalmed3010006.

29.

Testing the psychometric properties of the self-harm and suicide disclosure scale.

Frey LM, Higgins GE, Fulginiti A.

Psychiatry Res. 2018 Dec;270:134-142. doi: 10.1016/j.psychres.2018.09.016. Epub 2018 Sep 13.

PMID:
30245377
30.

Genome Architecture Mediates Transcriptional Control of Human Myogenic Reprogramming.

Liu S, Chen H, Ronquist S, Seaman L, Ceglia N, Meixner W, Chen PY, Higgins G, Baldi P, Smale S, Hero A, Muir LA, Rajapakse I.

iScience. 2018 Aug 31;6:232-246. doi: 10.1016/j.isci.2018.08.002. Epub 2018 Aug 8.

31.

New Features for Measuring Disease Activity in Pediatric Localized Scleroderma.

Li SC, Li X, Pope E, Stewart K, Higgins GC, Rabinovich CE, O'Neil KM, Haines KA, Laxer RM, Punaro M, Jacobe H, Andrews T, Wittkowski K, Nyirenda T, Foeldvari I, Torok KS.

J Rheumatol. 2018 Dec;45(12):1680-1688. doi: 10.3899/jrheum.171381. Epub 2018 Sep 15.

PMID:
30219769
32.

3D Shape Modeling for Cell Nuclear Morphological Analysis and Classification.

Kalinin AA, Allyn-Feuer A, Ade A, Fon GV, Meixner W, Dilworth D, Husain SS, de Wet JR, Higgins GA, Zheng G, Creekmore A, Wiley JW, Verdone JE, Veltri RW, Pienta KJ, Coffey DS, Athey BD, Dinov ID.

Sci Rep. 2018 Sep 12;8(1):13658. doi: 10.1038/s41598-018-31924-2. Erratum in: Sci Rep. 2018 Oct 26;8(1):16142.

33.

Whole tumor kinetics analysis of 18F-fluoromisonidazole dynamic PET scans of non-small cell lung cancer patients, and correlations with perfusion CT blood flow.

McGowan DR, Skwarski M, Papiez BW, Macpherson RE, Gleeson FV, Schnabel JA, Higgins GS, Fenwick JD.

EJNMMI Res. 2018 Aug 1;8(1):73. doi: 10.1186/s13550-018-0430-4.

34.

The new screening program to prevent cervical cancer using HPV DNA: getting the balance right in maintaining quality.

Garland SM, Dimech W, Collignon P; Australian Clinical Microbiologists Infectious Diseases Group, Cooley L, Nimmo GR, Smith DW, Baird R, Rawlinson W, Costa AM, Higgins G.

J Pathol Clin Res. 2018 Oct;4(4):207-212. doi: 10.1002/cjp2.110. Epub 2018 Sep 11.

35.

CDK1 inhibition sensitizes normal cells to DNA damage in a cell cycle dependent manner.

Prevo R, Pirovano G, Puliyadi R, Herbert KJ, Rodriguez-Berriguete G, O'Docherty A, Greaves W, McKenna WG, Higgins GS.

Cell Cycle. 2018;17(12):1513-1523. doi: 10.1080/15384101.2018.1491236. Epub 2018 Jul 25.

36.

Overview of Pediatric Rheumatology for the Primary Care Provider.

Li SC, Higgins GC.

Pediatr Clin North Am. 2018 Aug;65(4):xv-xvi. doi: 10.1016/j.pcl.2018.05.001. No abstract available.

PMID:
30031504
37.

Complications of Treatments for Pediatric Rheumatic Diseases.

Higgins GC.

Pediatr Clin North Am. 2018 Aug;65(4):827-854. doi: 10.1016/j.pcl.2018.04.008. Review.

PMID:
30031500
38.

A similarity-based approach to leverage multi-cohort medical data on the diagnosis and prognosis of Alzheimer's disease.

Zhang H, Zhu F, Dodge HH, Higgins GA, Omenn GS, Guan Y; Alzheimer's Disease Neuroimaging Initiative.

Gigascience. 2018 Jul 1;7(7). doi: 10.1093/gigascience/giy085.

39.

Nucleoporin 54 contributes to homologous recombination repair and post-replicative DNA integrity.

Rodriguez-Berriguete G, Granata G, Puliyadi R, Tiwana G, Prevo R, Wilson RS, Yu S, Buffa F, Humphrey TC, McKenna WG, Higgins GS.

Nucleic Acids Res. 2018 Sep 6;46(15):7731-7746. doi: 10.1093/nar/gky569.

40.

The STK35 locus contributes to normal gametogenesis and encodes a lncRNA responsive to oxidative stress.

Miyamoto Y, Whiley PAF, Goh HY, Wong C, Higgins G, Tachibana T, McMenamin PG, Mayne L, Loveland KL.

Biol Open. 2018 Aug 6;7(8). pii: bio032631. doi: 10.1242/bio.032631.

41.

Rapid valproic acid-induced modulation of the traumatic proteome in a porcine model of traumatic brain injury and hemorrhagic shock.

Weykamp M, Nikolian VC, Dennahy IS, Higgins GA, Georgoff PE, Remmer H, Ghandour MH, Alam HB.

J Surg Res. 2018 Aug;228:84-92. doi: 10.1016/j.jss.2018.02.046. Epub 2018 Apr 25.

PMID:
29907235
42.

Deep learning in pharmacogenomics: from gene regulation to patient stratification.

Kalinin AA, Higgins GA, Reamaroon N, Soroushmehr S, Allyn-Feuer A, Dinov ID, Najarian K, Athey BD.

Pharmacogenomics. 2018 May;19(7):629-650. doi: 10.2217/pgs-2018-0008. Epub 2018 Apr 26. Review.

43.

Effects of the NMDA receptor antagonists dizocilpine and Ro 63-1908 on delay-discounting and risky decision-making in a gambling task.

Higgins GA, Silenieks LB, MacMillan C, Zeeb FD, Thevarkunnel S.

Behav Brain Res. 2018 Aug 1;348:201-210. doi: 10.1016/j.bbr.2018.04.028. Epub 2018 Apr 22.

PMID:
29689373
44.

Healthcare Use Patterns and Economic Burden of Chronic Musculoskeletal Pain in Children before Diagnosis.

Tian F, Guittar P, Moore-Clingenpeel M, Higgins G, Ardoin SP, Spencer CH, Jones K, Thomas B, Akoghlanian S, Bout-Tabaku S.

J Pediatr. 2018 Jun;197:172-176. doi: 10.1016/j.jpeds.2018.01.076. Epub 2018 Apr 3.

PMID:
29625732
45.

4D-PET reconstruction using a spline-residue model with spatial and temporal roughness penalties.

Ralli GP, Chappell MA, McGowan DR, Sharma RA, Higgins GS, Fenwick JD.

Phys Med Biol. 2018 May 4;63(9):095013. doi: 10.1088/1361-6560/aabb62.

46.

Beyond PARP-POLθ as an anticancer target.

Higgins GS, Boulton SJ.

Science. 2018 Mar 16;359(6381):1217-1218. doi: 10.1126/science.aar5149. No abstract available.

PMID:
29590065
47.

Methods in renal research: Measurement of autophagic flux in the renal cortex ex vivo.

Higgins GC, Nguyen TV, Ramm G, Coughlan MT.

Nephrology (Carlton). 2018 Sep;23(9):815-820. doi: 10.1111/nep.13251.

PMID:
29504645
48.

Preclinical evidence for combining the 5-HT2C receptor agonist lorcaserin and varenicline as a treatment for nicotine dependence.

Fletcher PJ, Li Z, Silenieks LB, MacMillan C, DeLannoy I, Higgins GA.

Addict Biol. 2019 May;24(3):376-387. doi: 10.1111/adb.12602. Epub 2018 Mar 2.

PMID:
29498158
49.

Clinical Characteristics and Factors Associated With Disability and Impaired Quality of Life in Children With Juvenile Systemic Sclerosis: Results From the Childhood Arthritis and Rheumatology Research Alliance Legacy Registry.

Stevens BE, Torok KS, Li SC, Hershey N, Curran M, Higgins GC, Moore KF, Egla Rabinovich C, Dodson S, Stevens AM; Childhood Arthritis and Rheumatology Research Alliance Registry Investigators.

Arthritis Care Res (Hoboken). 2018 Dec;70(12):1806-1813. doi: 10.1002/acr.23547. Epub 2018 Nov 8.

50.

Past-year nonmedical use of prescription drugs among women on probation and parole: A cross-sectional study.

Hall MT, Ball D, Sears J, Higgins GE, Logan TK, Golder S.

Subst Abus. 2018;39(3):280-285. doi: 10.1080/08897077.2018.1442382. Epub 2018 Apr 5.

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