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Items: 1 to 50 of 769

1.

Nucleoporin 54 contributes to homologous recombination repair and post-replicative DNA integrity.

Rodriguez-Berriguete G, Granata G, Puliyadi R, Tiwana G, Prevo R, Wilson RS, Yu S, Buffa F, Humphrey TC, McKenna WG, Higgins GS.

Nucleic Acids Res. 2018 Jul 9. doi: 10.1093/nar/gky569. [Epub ahead of print]

PMID:
29986057
2.

The Stk35 locus contributes to normal gametogenesis and encodes a lncRNA responsive to oxidative stress.

Miyamoto Y, Whiley PAF, Goh HY, Wong C, Higgins G, Tachibana T, McMenamin P, Mayne L, Loveland KL.

Biol Open. 2018 Jul 3. pii: bio.032631. doi: 10.1242/bio.032631. [Epub ahead of print]

3.

Rapid valproic acid-induced modulation of the traumatic proteome in a porcine model of traumatic brain injury and hemorrhagic shock.

Weykamp M, Nikolian VC, Dennahy IS, Higgins GA, Georgoff PE, Remmer H, Ghandour MH, Alam HB.

J Surg Res. 2018 Aug;228:84-92. doi: 10.1016/j.jss.2018.02.046. Epub 2018 Apr 25.

PMID:
29907235
4.

Deep learning in pharmacogenomics: from gene regulation to patient stratification.

Kalinin AA, Higgins GA, Reamaroon N, Soroushmehr S, Allyn-Feuer A, Dinov ID, Najarian K, Athey BD.

Pharmacogenomics. 2018 May;19(7):629-650. doi: 10.2217/pgs-2018-0008. Epub 2018 Apr 26.

PMID:
29697304
5.

Effects of the NMDA receptor antagonists dizocilpine and Ro 63-1908 on delay-discounting and risky decision-making in a gambling task.

Higgins GA, Silenieks LB, MacMillan C, Zeeb FD, Thevarkunnel S.

Behav Brain Res. 2018 Aug 1;348:201-210. doi: 10.1016/j.bbr.2018.04.028. Epub 2018 Apr 22.

PMID:
29689373
6.

Healthcare Use Patterns and Economic Burden of Chronic Musculoskeletal Pain in Children before Diagnosis.

Tian F, Guittar P, Moore-Clingenpeel M, Higgins G, Ardoin SP, Spencer CH, Jones K, Thomas B, Akoghlanian S, Bout-Tabaku S.

J Pediatr. 2018 Jun;197:172-176. doi: 10.1016/j.jpeds.2018.01.076. Epub 2018 Apr 3.

PMID:
29625732
7.

4D-PET reconstruction using a spline-residue model with spatial and temporal roughness penalties.

Ralli GP, Chappell MA, McGowan DR, Sharma RA, Higgins GS, Fenwick JD.

Phys Med Biol. 2018 May 4;63(9):095013. doi: 10.1088/1361-6560/aabb62.

8.

Beyond PARP-POLθ as an anticancer target.

Higgins GS, Boulton SJ.

Science. 2018 Mar 16;359(6381):1217-1218. doi: 10.1126/science.aar5149. No abstract available.

PMID:
29590065
9.

Methods in renal research: Measurement of autophagic flux in the renal cortex ex vivo.

Higgins GC, Nguyen TV, Ramm G, Coughlan MT.

Nephrology (Carlton). 2018 Mar 5. doi: 10.1111/nep.13251. [Epub ahead of print] Review.

PMID:
29504645
10.

Preclinical evidence for combining the 5-HT2C receptor agonist lorcaserin and varenicline as a treatment for nicotine dependence.

Fletcher PJ, Li Z, Silenieks LB, MacMillan C, DeLannoy I, Higgins GA.

Addict Biol. 2018 Mar 2. doi: 10.1111/adb.12602. [Epub ahead of print]

PMID:
29498158
11.

Clinical characteristics and factors associated with disability and impaired quality of life in children with juvenile systemic sclerosis.

Stevens BE, Torok KS, Li SC, Hershey N, Curran M, Higgins GC, Moore KF, Rabinovich CE, Dodson S, Stevens AM; CARRA Registry Investigators; Childhood Arthritis Rheumatology Research Alliance Stanford CA.

Arthritis Care Res (Hoboken). 2018 Feb 18. doi: 10.1002/acr.23547. [Epub ahead of print]

PMID:
29457372
12.

Past-year nonmedical use of prescription drugs among women on probation and parole: A cross-sectional study.

Hall MT, Ball D, Sears J, Higgins GE, Logan TK, Golder S.

Subst Abus. 2018 Feb 16:1-6. doi: 10.1080/08897077.2018.1442382. [Epub ahead of print]

PMID:
29452065
13.

RAGE Deletion Confers Renoprotection by Reducing Responsiveness to Transforming Growth Factor-β and Increasing Resistance to Apoptosis.

Hagiwara S, Sourris K, Ziemann M, Tieqiao W, Mohan M, McClelland AD, Brennan E, Forbes J, Coughlan M, Harcourt B, Penfold S, Wang B, Higgins G, Pickering R, El-Osta A, Thomas MC, Cooper ME, Kantharidis P.

Diabetes. 2018 May;67(5):960-973. doi: 10.2337/db17-0538. Epub 2018 Feb 15.

PMID:
29449307
14.

Targeting tumour hypoxia: shifting focus from oxygen supply to demand.

Coates JT, Skwarski M, Higgins GS.

Br J Radiol. 2018 Feb 19:20170843. doi: 10.1259/bjr.20170843. [Epub ahead of print]

PMID:
29436847
15.

Oxidative Phosphorylation as an Emerging Target in Cancer Therapy.

Ashton TM, McKenna WG, Kunz-Schughart LA, Higgins GS.

Clin Cancer Res. 2018 Jun 1;24(11):2482-2490. doi: 10.1158/1078-0432.CCR-17-3070. Epub 2018 Feb 2. Review.

PMID:
29420223
16.

The pharmacoepigenomics informatics pipeline defines a pathway of novel and known warfarin pharmacogenomics variants.

Allyn-Feuer A, Ade A, Luzum JA, Higgins GA, Athey BD.

Pharmacogenomics. 2018 Apr;19(5):413-434. doi: 10.2217/pgs-2017-0186. Epub 2018 Feb 5.

17.

Coherent Control of a Single Trapped Rydberg Ion.

Higgins G, Pokorny F, Zhang C, Bodart Q, Hennrich M.

Phys Rev Lett. 2017 Dec 1;119(22):220501. doi: 10.1103/PhysRevLett.119.220501. Epub 2017 Nov 28.

PMID:
29286758
18.

Transcriptomic changes following valproic acid treatment promote neurogenesis and minimize secondary brain injury.

Nikolian VC, Dennahy IS, Higgins GA, Williams AM, Weykamp M, Georgoff PE, Eidy H, Ghandour MH, Chang P, Alam HB.

J Trauma Acute Care Surg. 2018 Mar;84(3):459-465. doi: 10.1097/TA.0000000000001765.

PMID:
29251707
19.

Valproic acid induces prosurvival transcriptomic changes in swine subjected to traumatic injury and hemorrhagic shock.

Georgoff PE, Nikolian VC, Higgins G, Chtraklin K, Eidy H, Ghandour MH, Williams A, Athey B, Alam HB.

J Trauma Acute Care Surg. 2018 Apr;84(4):642-649. doi: 10.1097/TA.0000000000001763.

PMID:
29251706
20.

Resolvin D1 regulates epithelial ion transport and inflammation in cystic fibrosis airways.

Ringholz FC, Higgins G, Hatton A, Sassi A, Moukachar A, Fustero-Torre C, Hollenhorst M, Sermet-Gaudelus I, Harvey BJ, McNally P, Urbach V.

J Cyst Fibros. 2017 Dec 7. pii: S1569-1993(17)30974-8. doi: 10.1016/j.jcf.2017.11.017. [Epub ahead of print]

PMID:
29233471
21.

The Future of Radiobiology.

Kirsch DG, Diehn M, Kesarwala AH, Maity A, Morgan MA, Schwarz JK, Bristow R, Demaria S, Eke I, Griffin RJ, Haas-Kogan D, Higgins GS, Kimmelman AC, Kimple RJ, Lombaert IM, Ma L, Marples B, Pajonk F, Park CC, Schaue D, Tran PT, Willers H, Wouters BG, Bernhard EJ.

J Natl Cancer Inst. 2018 Apr 1;110(4):329-340. doi: 10.1093/jnci/djx231.

PMID:
29126306
22.

Improvement of Blood-Brain Barrier Integrity in Traumatic Brain Injury and Hemorrhagic Shock Following Treatment With Valproic Acid and Fresh Frozen Plasma.

Nikolian VC, Dekker SE, Bambakidis T, Higgins GA, Dennahy IS, Georgoff PE, Williams AM, Andjelkovic AV, Alam HB.

Crit Care Med. 2018 Jan;46(1):e59-e66. doi: 10.1097/CCM.0000000000002800.

PMID:
29095204
23.

Low interim influenza vaccine effectiveness, Australia, 1 May to 24 September 2017.

Sullivan SG, Chilver MB, Carville KS, Deng YM, Grant KA, Higgins G, Komadina N, Leung VK, Minney-Smith CA, Teng D, Tran T, Stocks N, Fielding JE.

Euro Surveill. 2017 Oct;22(43). doi: 10.2807/1560-7917.ES.2017.22.43.17-00707.

24.

Role of impulsivity and reward in the anti-obesity actions of 5-HT2C receptor agonists.

Higgins GA, Zeeb FD, Fletcher PJ.

J Psychopharmacol. 2017 Nov;31(11):1403-1418. doi: 10.1177/0269881117735797. Epub 2017 Oct 26. Review.

PMID:
29072522
25.

Aeromonas species endogenous endophthalmitis.

Ryan L, Higgins G, Doyle M.

JMM Case Rep. 2017 May 4;4(5):e005094. doi: 10.1099/jmmcr.0.005094. eCollection 2017 May.

26.

The 'egg topping' technique for bone graft harvesting in hip arthroplasty.

Awad AS, Williams MG, Higgins GA.

Ann R Coll Surg Engl. 2018 Jan;100(1):80. doi: 10.1308/rcsann.2017.0125. Epub 2017 Sep 13. No abstract available.

PMID:
29022810
27.

IGF-1R associates with adverse outcomes after radical radiotherapy for prostate cancer.

Aleksic T, Verrill C, Bryant RJ, Han C, Worrall AR, Brureau L, Larré S, Higgins GS, Fazal F, Sabbagh A, Haider S, Buffa FM, Cole D, Macaulay VM.

Br J Cancer. 2017 Nov 21;117(11):1600-1606. doi: 10.1038/bjc.2017.337. Epub 2017 Oct 3.

PMID:
28972962
28.

Rodent Test of Attention and Impulsivity: The 5-Choice Serial Reaction Time Task.

Higgins GA, Silenieks LB.

Curr Protoc Pharmacol. 2017 Sep 11;78:5.49.1-5.49.34. doi: 10.1002/cpph.27.

PMID:
28892143
29.

Assessment of transition readiness in adolescents and young adults with chronic health conditions.

Jensen PT, Paul GV, LaCount S, Peng J, Spencer CH, Higgins GC, Boyle B, Kamboj M, Smallwood C, Ardoin SP.

Pediatr Rheumatol Online J. 2017 Sep 9;15(1):70. doi: 10.1186/s12969-017-0197-6.

30.

Establishing contemporary trends in hepatitis B sero-epidemiology in an Indigenous population.

Davies J, Li SQ, Tong SY, Baird RW, Beaman M, Higgins G, Cowie BC, Condon JR, Davis JS.

PLoS One. 2017 Sep 8;12(9):e0184082. doi: 10.1371/journal.pone.0184082. eCollection 2017.

31.

Pharmacological Modulation of 5-HT2C Receptor Activity Produces Bidirectional Changes in Locomotor Activity, Responding for a Conditioned Reinforcer, and Mesolimbic DA Release in C57BL/6 Mice.

Browne CJ, Ji X, Higgins GA, Fletcher PJ, Harvey-Lewis C.

Neuropsychopharmacology. 2017 Oct;42(11):2178-2187. doi: 10.1038/npp.2017.124. Epub 2017 Jun 13.

PMID:
28720903
32.

TOPK modulates tumour-specific radiosensitivity and correlates with recurrence after prostate radiotherapy.

Pirovano G, Ashton TM, Herbert KJ, Bryant RJ, Verrill CL, Cerundolo L, Buffa FM, Prevo R, Harrap I, Ryan AJ, Macaulay V, McKenna WG, Higgins GS.

Br J Cancer. 2017 Aug 8;117(4):503-512. doi: 10.1038/bjc.2017.197. Epub 2017 Jul 4.

33.

Correlates of HIV Risks Among Women on Probation and Parole.

Engstrom M, Winham KM, Golder S, Higgins G, Renn T, Logan TK.

AIDS Educ Prev. 2017 Jun;29(3):256-273. doi: 10.1521/aeap.2017.29.3.256.

PMID:
28650226
34.

18 F-fluoromisonidazole uptake in advanced stage non-small cell lung cancer: A voxel-by-voxel PET kinetics study.

McGowan DR, Macpherson RE, Hackett SL, Liu D, Gleeson FV, McKenna WG, Higgins GS, Fenwick JD.

Med Phys. 2017 Sep;44(9):4665-4676. doi: 10.1002/mp.12416. Epub 2017 Jul 21.

35.

Childhood Victimization, Attachment, Coping, and Substance Use Among Victimized Women on Probation and Parole.

Dishon-Brown A, Golder S, Renn T, Winham K, Higgins GE, Logan TK.

Violence Vict. 2017 Jun 1;32(3):431-451. doi: 10.1891/0886-6708.VV-D-15-00100. Epub 2017 May 17.

PMID:
28516830
36.

Depletion of signal recognition particle 72kDa increases radiosensitivity.

Prevo R, Tiwana GS, Maughan TS, Buffa FM, McKenna WG, Higgins GS.

Cancer Biol Ther. 2017 Jun 3;18(6):425-432. doi: 10.1080/15384047.2017.1323587. Epub 2017 May 11.

37.

18F-FPP: A PET Ligand for the 5-HT2C Receptor?

Higgins GA.

ACS Chem Neurosci. 2017 May 17;8(5):904-907. doi: 10.1021/acschemneuro.7b00133. Epub 2017 May 1.

PMID:
28459529
38.

Mining the topography and dynamics of the 4D Nucleome to identify novel CNS drug pathways.

Higgins GA, Allyn-Feuer A, Georgoff P, Nikolian V, Alam HB, Athey BD.

Methods. 2017 Jul 1;123:102-118. doi: 10.1016/j.ymeth.2017.03.012. Epub 2017 Apr 4. Review.

PMID:
28385536
39.

Studies To Examine Potential Tolerability Differences between the 5-HT2C Receptor Selective Agonists Lorcaserin and CP-809101.

Higgins GA, Silenieks LB, Patrick A, De Lannoy IAM, Fletcher PJ, Parker LA, MacLusky NJ, Sullivan LC, Chavera TA, Berg KA.

ACS Chem Neurosci. 2017 May 17;8(5):1074-1084. doi: 10.1021/acschemneuro.6b00444. Epub 2017 Mar 24.

PMID:
28338324
40.

Network Reconstruction Reveals that Valproic Acid Activates Neurogenic Transcriptional Programs in Adult Brain Following Traumatic Injury.

Higgins GA, Georgoff P, Nikolian V, Allyn-Feuer A, Pauls B, Higgins R, Athey BD, Alam HE.

Pharm Res. 2017 Aug;34(8):1658-1672. doi: 10.1007/s11095-017-2130-6. Epub 2017 Mar 7.

41.

Uncovering the influence of the FGFR1 pathway on glioblastoma radiosensitivity.

Sayal KK, Higgins GS, Hammond EM.

Ann Transl Med. 2016 Dec;4(24):538. doi: 10.21037/atm.2016.11.65. No abstract available.

42.

MDMA-induced neurotoxicity of serotonin neurons involves autophagy and rilmenidine is protective against its pathobiology.

Mercer LD, Higgins GC, Lau CL, Lawrence AJ, Beart PM.

Neurochem Int. 2017 May;105:80-90. doi: 10.1016/j.neuint.2017.01.010. Epub 2017 Jan 23.

PMID:
28122248
43.

Examining the Relationship Between Childhood Victimization, High-Risk Behaviors, and Health Among Criminal Justice-Involved Women.

Renn T, Golder S, Higgins G, Logan TK, Winham KM.

J Correct Health Care. 2017 Jan;23(1):104-121. doi: 10.1177/1078345816685847.

PMID:
28100146
44.

Effects of 5-HT1A, 5-HT2A and 5-HT2C receptor agonists and antagonists on responding for a conditioned reinforcer and its enhancement by methylphenidate.

Fletcher PJ, Zeeb FD, Browne CJ, Higgins GA, Soko AD.

Psychopharmacology (Berl). 2017 Mar;234(5):889-902. doi: 10.1007/s00213-017-4529-5. Epub 2017 Jan 18.

PMID:
28097374
45.

A quantitative immunoassay for lung cancer biomarker CIZ1b in patient plasma.

Coverley D, Higgins G, West D, Jackson OT, Dowle A, Haslam A, Ainscough E, Chalkley R, White J.

Clin Biochem. 2017 Apr;50(6):336-343. doi: 10.1016/j.clinbiochem.2016.11.015. Epub 2016 Nov 17.

46.

A new roadmap to improve translation of imaging biomarkers.

Skwarski M, Higgins GS.

Br J Cancer. 2016 Dec 6;115(12):1443-1444. doi: 10.1038/bjc.2016.374. Epub 2016 Nov 15. No abstract available.

47.

Dose and Fractionation in Radiation Therapy of Curative Intent for Non-Small Cell Lung Cancer: Meta-Analysis of Randomized Trials.

Ramroth J, Cutter DJ, Darby SC, Higgins GS, McGale P, Partridge M, Taylor CW.

Int J Radiat Oncol Biol Phys. 2016 Nov 15;96(4):736-747. doi: 10.1016/j.ijrobp.2016.07.022. Epub 2016 Jul 25.

48.

Profile of Antiemetic Activity of Netupitant Alone or in Combination with Palonosetron and Dexamethasone in Ferrets and Suncus murinus (House Musk Shrew).

Rudd JA, Ngan MP, Lu Z, Higgins GA, Giuliano C, Lovati E, Pietra C.

Front Pharmacol. 2016 Aug 31;7:263. doi: 10.3389/fphar.2016.00263. eCollection 2016.

49.

You Are What You Eat: The Impact of Nutrition on Alcohol and Drug Use.

Schroeder RD, Higgins GE.

Subst Use Misuse. 2017 Jan 2;52(1):10-24. Epub 2016 Sep 12.

PMID:
27617497
50.

Alterations in the human proteome following administration of valproic acid.

Georgoff PE, Halaweish I, Nikolian VC, Higgins GA, Bonham T, Tafatia C, Remmer H, Menon R, Liu B, Li Y, Alam HB.

J Trauma Acute Care Surg. 2016 Dec;81(6):1020-1027.

PMID:
27602906

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