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Items: 1 to 50 of 341

1.

The E3 ubiquitin ligase MIB2 enhances inflammation by degrading the deubiquitinating enzyme CYLD.

Uematsu A, Kido K, Takahashi H, Takahashi C, Yanagihara Y, Saeki N, Yoshida S, Maekawa M, Honda M, Kai T, Shimizu K, Higashiyama S, Imai Y, Tokunaga F, Sawasaki T.

J Biol Chem. 2019 Sep 20;294(38):14135-14148. doi: 10.1074/jbc.RA119.010119. Epub 2019 Jul 31.

PMID:
31366726
2.

Cullin-3/KCTD10 complex is essential for K27-polyubiquitination of EIF3D in human hepatocellular carcinoma HepG2 cells.

Maekawa M, Hiyoshi H, Nakayama J, Kido K, Sawasaki T, Semba K, Kubota E, Joh T, Higashiyama S.

Biochem Biophys Res Commun. 2019 Sep 3;516(4):1116-1122. doi: 10.1016/j.bbrc.2019.07.010. Epub 2019 Jul 5.

3.

A noninvasive diagnostic approach using per-rectal portal scintigraphy for sinusoidal obstruction syndrome after allogeneic hematopoietic cell transplantation.

Okamura H, Koh H, Takakuwa T, Ido K, Makuuchi Y, Ine S, Nanno S, Nakashima Y, Nakane T, Jogo A, Yamamoto A, Hamuro M, Kotani K, Kawabe J, Higashiyama S, Yoshida A, Shiomi S, Ohsawa M, Hino M, Nakamae H.

Bone Marrow Transplant. 2019 May 14. doi: 10.1038/s41409-019-0537-x. [Epub ahead of print] No abstract available.

PMID:
31089276
4.

SNX9 determines the surface levels of integrin β1 in vascular endothelial cells: Implication in poor prognosis of human colorectal cancers overexpressing SNX9.

Tanigawa K, Maekawa M, Kiyoi T, Nakayama J, Kitazawa R, Kitazawa S, Semba K, Taguchi T, Akita S, Yoshida M, Ishimaru K, Watanabe Y, Higashiyama S.

J Cell Physiol. 2019 Aug;234(10):17280-17294. doi: 10.1002/jcp.28346. Epub 2019 Feb 19.

5.

Konjac ceramide (kCer) regulates keratinocyte migration by Sema3A-like repulsion mechanism.

Usuki S, Tamura N, Tamura T, Higashiyama S, Tanji K, Mitsutake S, Inoue A, Aoki J, Mukai K, Igarashi Y.

Biochem Biophys Rep. 2019 Jan 3;17:132-138. doi: 10.1016/j.bbrep.2018.11.004. eCollection 2019 Mar.

6.

Prognostic significance of pretreatment 18F-fluorodeoxyglucose positron emission tomography evaluation using metabolic tumor volume of the primary tumor and lymph nodes in advanced hypopharyngeal cancer.

Okazaki E, Kawabe J, Oishi M, Hosono M, Higashiyama S, Teranishi Y, Shiomi S, Iguchi H, Miki Y.

Head Neck. 2019 Mar;41(3):739-747. doi: 10.1002/hed.25429. Epub 2018 Dec 7.

PMID:
30536887
7.

Semaphorin 3F and Netrin-1: The Novel Function as a Regulator of Tumor Microenvironment.

Nakayama H, Kusumoto C, Nakahara M, Fujiwara A, Higashiyama S.

Front Physiol. 2018 Nov 23;9:1662. doi: 10.3389/fphys.2018.01662. eCollection 2018. Review.

8.

Cullin-3/KCTD10 E3 complex is essential for Rac1 activation through RhoB degradation in human epidermal growth factor receptor 2-positive breast cancer cells.

Murakami A, Maekawa M, Kawai K, Nakayama J, Araki N, Semba K, Taguchi T, Kamei Y, Takada Y, Higashiyama S.

Cancer Sci. 2019 Feb;110(2):650-661. doi: 10.1111/cas.13899. Epub 2019 Jan 8.

9.

Activation of Pyk2 by CaM kinase II in cultured hypothalamic neurons and gonadotroph cells.

Okitsu-Sakurayama S, Higa-Nakamine S, Torihara H, Takahashi H, Higashiyama S, Yamamoto H.

J Cell Physiol. 2019 May;234(5):6865-6875. doi: 10.1002/jcp.27443. Epub 2018 Nov 11.

PMID:
30417368
10.

Biochemical and histological evidence of deteriorated bioprosthetic valve leaflets: the accumulation of fibrinogen and plasminogen.

Sakaue T, Nakaoka H, Shikata F, Aono J, Kurata M, Uetani T, Hamaguchi M, Kojima A, Uchita S, Yasugi T, Higashi H, Suzuki J, Ikeda S, Higaki J, Higashiyama S, Izutani H.

Biol Open. 2018 Aug 8;7(8). pii: bio034009. doi: 10.1242/bio.034009.

11.

Heterogeneous liver uptake of Tc-99m-GSA as quantified through SPECT/CT helps to evaluate the degree of liver fibrosis: A retrospective observational study.

Kotani K, Kawabe J, Higashiyama S, Yoshida A, Kawamura E, Tamori A, Shiomi S, Kawada N.

Medicine (Baltimore). 2018 Aug;97(31):e11765. doi: 10.1097/MD.0000000000011765.

12.

[Using Super Resolution to Denoise on PET Images].

Katayama Y, Ueda K, Hiura S, Kimura D, Takao Y, Yamanaga T, Ichida T, Higashiyama S, Kawabe J.

Nihon Hoshasen Gijutsu Gakkai Zasshi. 2018;74(7):653-660. doi: 10.6009/jjrt.2018_JSRT_74.7.653. Japanese.

13.

18-Fluoride-labeled sodium fluoride positron emission tomography is effective for assessing the therapeutic effect of Radium 223; a case report.

Hamada K, Tamada S, Iguchi T, Kato M, Higashiyama S, Kawabe J, Nakatani T.

Urol Case Rep. 2018 May 5;19:31-33. doi: 10.1016/j.eucr.2018.04.005. eCollection 2018 Jul. No abstract available.

14.

Epithelial membrane protein 1 promotes tumor metastasis by enhancing cell migration via copine-III and Rac1.

Ahmat Amin MKB, Shimizu A, Zankov DP, Sato A, Kurita S, Ito M, Maeda T, Yoshida T, Sakaue T, Higashiyama S, Kawauchi A, Ogita H.

Oncogene. 2018 Oct;37(40):5416-5434. doi: 10.1038/s41388-018-0286-0. Epub 2018 Jun 4.

15.

Cullin 3 regulates ADAMs-mediated ectodomain shedding of amphiregulin.

Nakayama H, Sakaue T, Maekawa M, Fujisaki A, Higashiyama S.

Biochem Biophys Res Commun. 2018 Apr 30;499(1):17-23. doi: 10.1016/j.bbrc.2018.03.097. Epub 2018 Mar 21.

PMID:
29550478
16.

A CCR4 antagonist enhances DC activation and homing to the regional lymph node and shows potent vaccine adjuvant activity through the inhibition of regulatory T-cell recruitment.

Yamamoto S, Matsuo K, Nagakubo D, Higashiyama S, Nishiwaki K, Oiso N, Kawada A, Yoshie O, Nakayama T.

J Pharmacol Sci. 2018 Mar;136(3):165-171. doi: 10.1016/j.jphs.2018.02.001. Epub 2018 Feb 8.

17.

Phytosphingosine is a novel activator of GPR120.

Nagasawa T, Nakamichi H, Hama Y, Higashiyama S, Igarashi Y, Mitsutake S.

J Biochem. 2018 Jul 1;164(1):27-32. doi: 10.1093/jb/mvy017.

PMID:
29373685
18.

The Cullin-3-Rbx1-KCTD10 complex controls endothelial barrier function via K63 ubiquitination of RhoB.

Kovačević I, Sakaue T, Majoleé J, Pronk MC, Maekawa M, Geerts D, Fernandez-Borja M, Higashiyama S, Hordijk PL.

J Cell Biol. 2018 Mar 5;217(3):1015-1032. doi: 10.1083/jcb.201606055. Epub 2018 Jan 22.

19.

Corrigendum: The CUL3-SPOP-DAXX axis is a novel regulator of VEGFR2 expression in vascular endothelial cells.

Sakaue T, Sakakibara I, Uesugi T, Fujisaki A, Nakashiro KI, Hamakawa H, Kubota E, Joh T, Imai Y, Izutani H, Higashiyama S.

Sci Rep. 2017 Dec 22;7:46915. doi: 10.1038/srep46915.

20.

[Novel function of axon guidance molecule as a regulator of tumor microenvironment].

Nakayama H, Higashiyama S.

Nihon Yakurigaku Zasshi. 2017;150(6):286-292. doi: 10.1254/fpj.150.286. Review. Japanese. No abstract available.

PMID:
29225291
21.

Both Autocrine Signaling and Paracrine Signaling of HB-EGF Enhance Ocular Neovascularization.

Inoue Y, Shimazawa M, Nakamura S, Takata S, Hashimoto Y, Izawa H, Masuda T, Tsuruma K, Sakaue T, Nakayama H, Higashiyama S, Hara H.

Arterioscler Thromb Vasc Biol. 2018 Jan;38(1):174-185. doi: 10.1161/ATVBAHA.117.310337. Epub 2017 Nov 30.

PMID:
29191924
22.

Scatter Correction of Septal Penetration for 123I-IMP Cerebral Blood Flow SPECT Adding Radioactivity from the Outside of Field of View-Comparison between Simulation-based and Multi-window Scatter Corrections.

Yamanaga T, Katayama Y, Nakama S, Kakimi A, Nagahata T, Kishimoto K, Ichida T, Higashiyama S, Kawabe J, Shiomi S.

Nihon Hoshasen Gijutsu Gakkai Zasshi. 2017;73(10):1028-1038. doi: 10.6009/jjrt.2017_JSRT_73.10.1028. Japanese.

23.

Cullin-3 and its adaptor protein ANKFY1 determine the surface level of integrin β1 in endothelial cells.

Maekawa M, Tanigawa K, Sakaue T, Hiyoshi H, Kubota E, Joh T, Watanabe Y, Taguchi T, Higashiyama S.

Biol Open. 2017 Nov 15;6(11):1707-1719. doi: 10.1242/bio.029579.

24.

Regional Liver Disorder with Differences in the Accumulation of 99mTc-phytate and 99mTc-galactosyl Human Serum Albumin.

Kotani K, Kawabe J, Higashiyama S, Shiomi S.

World J Nucl Med. 2017 Oct-Dec;16(4):320-323. doi: 10.4103/1450-1147.215493.

25.

Prospect of divergent roles for the CUL3 system in vascular endothelial cell function and angiogenesis.

Sakaue T, Maekawa M, Nakayama H, Higashiyama S.

J Biochem. 2017 Oct 1;162(4):237-245. doi: 10.1093/jb/mvx051. Review.

PMID:
28981750
26.

Mechanism of Proliferation of Cultured Human Corneal Endothelial Cells.

Joko T, Shiraishi A, Kobayashi T, Ohashi Y, Higashiyama S.

Cornea. 2017 Nov;36 Suppl 1:S41-S45. doi: 10.1097/ICO.0000000000001337. Review.

PMID:
28902018
27.

Efficient induction of inner ear hair cell-like cells from mouse ES cells using combination of Math1 transfection and conditioned medium from ST2 stromal cells.

Ouji Y, Sakagami M, Omori H, Higashiyama S, Kawai N, Kitahara T, Wanaka A, Yoshikawa M.

Stem Cell Res. 2017 Aug;23:50-56. doi: 10.1016/j.scr.2017.06.013. Epub 2017 Jul 1.

28.

Downregulation of ANP32B exerts anti-apoptotic effects in hepatocellular carcinoma.

Ohno Y, Koizumi M, Nakayama H, Watanabe T, Hirooka M, Tokumoto Y, Kuroda T, Abe M, Fukuda S, Higashiyama S, Kumagi T, Hiasa Y.

PLoS One. 2017 May 9;12(5):e0177343. doi: 10.1371/journal.pone.0177343. eCollection 2017.

29.

Usefulness of Stereotactic Radiotherapy Using CyberKnife for Recurrent Lymph Node Metastasis of Differentiated Thyroid Cancer.

Kawabe J, Higashiyama S, Sougawa M, Yoshida A, Kotani K, Shiomi S.

Case Rep Endocrinol. 2017;2017:7956726. doi: 10.1155/2017/7956726. Epub 2017 Mar 15.

30.

Glutamate-dependent ectodomain shedding of neuregulin-1 type II precursors in rat forebrain neurons.

Iwakura Y, Wang R, Inamura N, Araki K, Higashiyama S, Takei N, Nawa H.

PLoS One. 2017 Mar 28;12(3):e0174780. doi: 10.1371/journal.pone.0174780. eCollection 2017.

31.

The CUL3-SPOP-DAXX axis is a novel regulator of VEGFR2 expression in vascular endothelial cells.

Sakaue T, Sakakibara I, Uesugi T, Fujisaki A, Nakashiro KI, Hamakawa H, Kubota E, Joh T, Imai Y, Izutani H, Higashiyama S.

Sci Rep. 2017 Feb 20;7:42845. doi: 10.1038/srep42845. Erratum in: Sci Rep. 2017 Dec 22;7:46915.

32.

Proteomics-based analysis of lung injury-induced proteins in a mouse model of common bile duct ligation.

Sakaue T, Shikata F, Utsunomiya K, Fukae S, Kurata M, Nakaoka H, Okazaki M, Kawanishi Y, Kojima A, Higashiyama S, Izutani H.

Surgery. 2017 Jun;161(6):1525-1535. doi: 10.1016/j.surg.2016.12.017. Epub 2017 Jan 28.

33.

Diffuse Gallium-67 Accumulation in the Left Atrial Wall Detected Using SPECT/CT Fusion Images.

Kotani K, Kawabe J, Higashiyama S, Yoshida A, Shiomi S.

Case Rep Radiol. 2016;2016:6374584. doi: 10.1155/2016/6374584. Epub 2016 Dec 20.

34.

Neddylated Cullin 3 is required for vascular endothelial-cadherin-mediated endothelial barrier function.

Sakaue T, Fujisaki A, Nakayama H, Maekawa M, Hiyoshi H, Kubota E, Joh T, Izutani H, Higashiyama S.

Cancer Sci. 2017 Feb;108(2):208-215. doi: 10.1111/cas.13133.

35.

Parahippocampal Atrophy is Associated with Depressive Symptoms in Alzheimer's Disease.

Uchida K, Matsuda Y, Nakanishi A, Hashimoto H, Tagawa R, Shimada A, Muramatsu T, Kawarada Y, Yoshida A, Higashiyama S, Kawabe J, Kai T, Shiomi S, Mori H, Inoue K.

Osaka City Med J. 2016 Dec;62(2):59-67.

PMID:
30550711
36.

Stimulated release and functional activity of surface expressed metalloproteinase ADAM17 in exosomes.

Groth E, Pruessmeyer J, Babendreyer A, Schumacher J, Pasqualon T, Dreymueller D, Higashiyama S, Lorenzen I, Grötzinger J, Cataldo D, Ludwig A.

Biochim Biophys Acta. 2016 Nov;1863(11):2795-2808. doi: 10.1016/j.bbamcr.2016.09.002. Epub 2016 Sep 4.

37.

[Imaging of hyperparathyroidism-Ultrasonography and 99mTc-MIBI scintigraphy-].

Kawabe J, Higashiyama S, Yoshida A, Kotani K, Shiomi S.

Clin Calcium. 2016 Jun;26(6):867-74. doi: CliCa1606867874. Japanese.

PMID:
27230842
38.

Evaluation of ablation of thyroid remnants with 1850 MBq iodine-131 in 67 patients with thyroid cancer.

Kawabe J, Higashiyama S, Kotani K, Yoshida A, Onoda N, Shiomi S.

Q J Nucl Med Mol Imaging. 2019 Mar;63(1):68-75. doi: 10.23736/S1824-4785.16.02839-9. Epub 2016 Apr 29.

PMID:
27125316
39.

Ectodomain Shedding of Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE-1) Is Induced by Vascular Endothelial Growth Factor A (VEGF-A).

Nishida-Fukuda H, Araki R, Shudou M, Okazaki H, Tomono Y, Nakayama H, Fukuda S, Sakaue T, Shirakata Y, Sayama K, Hashimoto K, Detmar M, Higashiyama S, Hirakawa S.

J Biol Chem. 2016 May 13;291(20):10490-500. doi: 10.1074/jbc.M115.683201. Epub 2016 Mar 10.

40.

Two clonal types of human skin fibroblasts with different potentials for proliferation and tissue remodeling ability.

Hiraoka C, Toki F, Shiraishi K, Sayama K, Nishimura EK, Miura H, Higashiyama S, Nanba D.

J Dermatol Sci. 2016 May;82(2):84-94. doi: 10.1016/j.jdermsci.2016.01.009. Epub 2016 Jan 29.

PMID:
26867959
41.

Reversible interconversion and maintenance of mammary epithelial cell characteristics by the ligand-regulated EGFR system.

Fukuda S, Nishida-Fukuda H, Nanba D, Nakashiro K, Nakayama H, Kubota H, Higashiyama S.

Sci Rep. 2016 Feb 2;6:20209. doi: 10.1038/srep20209.

42.

Rotation is the primary motion of paired human epidermal keratinocytes.

Tate S, Imai M, Matsushita N, Nishimura EK, Higashiyama S, Nanba D.

J Dermatol Sci. 2015 Sep;79(3):194-202. doi: 10.1016/j.jdermsci.2015.05.008. Epub 2015 Jun 10.

PMID:
26126707
43.

The Relationship Between Medial Temporal Lobe Atrophy and Cognitive Impairment in Patients With Dementia With Lewy Bodies.

Tagawa R, Hashimoto H, Nakanishi A, Kawarada Y, Muramatsu T, Matsuda Y, Kataoka K, Shimada A, Uchida K, Yoshida A, Higashiyama S, Kawabe J, Kai T, Shiomi S, Mori H, Inoue K.

J Geriatr Psychiatry Neurol. 2015 Dec;28(4):249-54. doi: 10.1177/0891988715590210. Epub 2015 Jun 11.

PMID:
26071442
44.

Cell motion predicts human epidermal stemness.

Nanba D, Toki F, Tate S, Imai M, Matsushita N, Shiraishi K, Sayama K, Toki H, Higashiyama S, Barrandon Y.

J Cell Biol. 2015 Apr 27;209(2):305-15. doi: 10.1083/jcb.201409024. Epub 2015 Apr 20.

45.

Correlation between right medial temporal lobe atrophy and persecutory delusions in patients with dementia of the Alzheimer's type demonstrated on VSRAD advance.

Tagawa R, Hashimoto H, Matsuda Y, Uchida K, Yoshida A, Higashiyama S, Kawabe J, Toshihiro K, Shiomi S, Mori H, Inoue K.

Osaka City Med J. 2014 Dec;60(2):73-80.

PMID:
25803882
46.

Long‑term exposure to leptin enhances the growth of prostate cancer cells.

Noda T, Kikugawa T, Tanji N, Miura N, Asai S, Higashiyama S, Yokoyama M.

Int J Oncol. 2015 Apr;46(4):1535-42. doi: 10.3892/ijo.2015.2845. Epub 2015 Jan 23.

PMID:
25625287
47.

High-throughput synthesis of stable isotope-labeled transmembrane proteins for targeted transmembrane proteomics using a wheat germ cell-free protein synthesis system.

Takemori N, Takemori A, Matsuoka K, Morishita R, Matsushita N, Aoshima M, Takeda H, Sawasaki T, Endo Y, Higashiyama S.

Mol Biosyst. 2015 Feb;11(2):361-5. doi: 10.1039/c4mb00556b. Epub 2014 Nov 28.

PMID:
25431973
48.

131I abnormal uptake by the thyroid bed from Zuckerkandl tubercle diagnosis by 131I SPECT/CT.

Kawabe J, Higashiyama S, Kotani K, Onoda N, Shiomi S.

Clin Nucl Med. 2015 Mar;40(3):275-7. doi: 10.1097/RLU.0000000000000574.

PMID:
25140558
49.

ADAM17 promotes proliferation of collecting duct kidney epithelial cells through ERK activation and increased glycolysis in polycystic kidney disease.

Beck Gooz M, Maldonado EN, Dang Y, Amria MY, Higashiyama S, Abboud HE, Lemasters JJ, Bell PD.

Am J Physiol Renal Physiol. 2014 Sep 1;307(5):F551-9. doi: 10.1152/ajprenal.00218.2014. Epub 2014 Jun 4.

50.

Pathophysiology of lung injury induced by common bile duct ligation in mice.

Shikata F, Sakaue T, Nakashiro K, Okazaki M, Kurata M, Okamura T, Okura M, Ryugo M, Nakamura Y, Yasugi T, Higashiyama S, Izutani H.

PLoS One. 2014 Apr 14;9(4):e94550. doi: 10.1371/journal.pone.0094550. eCollection 2014.

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