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Items: 1 to 50 of 824

1.

Development of nobiletin-methyl hesperidin amorphous solid dispersion: novel application of methyl hesperidin as an excipient for hot-melt extrusion.

Iwashita M, Hashizume K, Umehara M, Ishigami T, Onishi S, Yamamoto M, Higashi K, Moribe K.

Int J Pharm. 2019 Jan 14. pii: S0378-5173(19)30036-5. doi: 10.1016/j.ijpharm.2018.12.092. [Epub ahead of print]

PMID:
30654059
2.

Real-world safety and efficacy of sofosbuvir and ledipasvir for elderly patients.

Tamai H, Shingaki N, Ida Y, Shimizu R, Maeshima S, Okamura J, Kawashima A, Nakao T, Hara T, Matsutani H, Nishikawa I, Higashi K.

JGH Open. 2018 Sep 19;2(6):300-306. doi: 10.1002/jgh3.12088. eCollection 2018 Dec.

3.

The Relationship Between Microbial Community Structures and Environmental Parameters Revealed by Metagenomic Analysis of Hot Spring Water in the Kirishima Area, Japan.

Nishiyama E, Higashi K, Mori H, Suda K, Nakamura H, Omori S, Maruyama S, Hongoh Y, Kurokawa K.

Front Bioeng Biotechnol. 2018 Dec 20;6:202. doi: 10.3389/fbioe.2018.00202. eCollection 2018.

4.

Combination of Roll Grinding and High-Pressure Homogenization Can Prepare Stable Bicelles for Drug Delivery.

Matsuo S, Higashi K, Moribe K, Kimura SI, Itai S, Kondo H, Iwao Y.

Nanomaterials (Basel). 2018 Dec 3;8(12). pii: E998. doi: 10.3390/nano8120998.

5.

Nodular gastritis in association with gastric cancer development before and after Helicobacter pylori eradication.

Nishikawa I, Kato J, Terasoma S, Matsutani H, Tamaki H, Tamaki T, Kuwashima F, Nakata H, Tomeki T, Matsunaka H, Ibata Y, Yamashita Y, Maekita T, Higashi K, Ichinose M.

JGH Open. 2018 Mar 25;2(3):80-86. doi: 10.1002/jgh3.12049. eCollection 2018 Jun.

6.

Microbes Culture System Using Cellulose Tubes and Photocatalyst-Coated Glass Balls.

Saito K, Fujimoto K, Higashi K, Miki N.

Conf Proc IEEE Eng Med Biol Soc. 2018 Jul;2018:5741-5744. doi: 10.1109/EMBC.2018.8513570.

PMID:
30441640
7.

Polyamines stimulate the CHSY1 synthesis through the unfolding of the RNA G-quadruplex at the 5'-untraslated region.

Yamaguchi K, Asakura K, Imamura M, Kawai G, Sakamoto T, Furihata T, Linhardt RJ, Igarashi K, Toida T, Higashi K.

Biochem J. 2018 Dec 6;475(23):3797-3812. doi: 10.1042/BCJ20180672.

PMID:
30401686
8.

Development of a Triple-Coaxial Flow Device for Fabricating a Hydrogel Microtube and Its Application to Bioremediation.

Fujimoto K, Higashi K, Onoe H, Miki N.

Micromachines (Basel). 2018 Feb 12;9(2). pii: E76. doi: 10.3390/mi9020076.

9.

Hydrogel Fiber Cultivation Method for Forming Bacterial Cellulose Microspheres.

Higashi K, Miki N.

Micromachines (Basel). 2018 Jan 17;9(1). pii: E36. doi: 10.3390/mi9010036.

10.

Identification of a Novel Bone Marrow Cell-Derived Accelerator of Fibrotic Liver Regeneration Through Mobilization of Hepatic Progenitor Cells in Mice.

Yanagawa T, Sumiyoshi H, Higashi K, Nakao S, Higashiyama R, Fukumitsu H, Minakawa K, Chiba Y, Suzuki Y, Sumida K, Saito K, Kamiya A, Inagaki Y.

Stem Cells. 2019 Jan;37(1):89-101. doi: 10.1002/stem.2916. Epub 2018 Oct 31.

PMID:
30270488
11.

Anti-cataract Effect of Resveratrol in High-Glucose-Treated Streptozotocin-Induced Diabetic Rats.

Higashi Y, Higashi K, Mori A, Sakamoto K, Ishii K, Nakahara T.

Biol Pharm Bull. 2018;41(10):1586-1592. doi: 10.1248/bpb.b18-00328.

12.

Long-Term Outcomes of Patients with Squamous Cell Carcinoma of the Temporal Bone after Concomitant Chemoradiotherapy.

Shiga K, Katagiri K, Saitoh D, Ogawa T, Higashi K, Ariga H.

J Neurol Surg B Skull Base. 2018 Oct;79(Suppl 4):S316-S321. doi: 10.1055/s-0038-1651522. Epub 2018 May 14.

PMID:
30210984
13.

An Insight into Stabilization Mechanism of a Solid Dispersion of Indomethacin/Partially Hydrolyzed Polyvinyl Alcohol Prepared by Hot-Melt Extrusion.

Benjasirimongkol P, Ueda K, Higashi K, Sriamornsak P, Moribe K.

Chem Pharm Bull (Tokyo). 2018;66(9):859-865. doi: 10.1248/cpb.c18-00362.

14.

DNA-loaded nano-adjuvant formed with a vitamin E-scaffold intracellular environmentally-responsive lipid-like material for cancer immunotherapy.

Kawai M, Nakamura T, Miura N, Maeta M, Tanaka H, Ueda K, Higashi K, Moribe K, Tange K, Nakai Y, Yoshioka H, Harashima H, Akita H.

Nanomedicine. 2018 Nov;14(8):2587-2597. doi: 10.1016/j.nano.2018.08.006. Epub 2018 Aug 29.

PMID:
30170077
15.

GLI1 Inhibitors Identified by Target Protein Oriented Natural Products Isolation (TPO-NAPI) with Hedgehog Inhibition.

Arai MA, Ochi F, Makita Y, Chiba T, Higashi K, Suganami A, Tamura Y, Toida T, Iwama A, Sadhu SK, Ahmed F, Ishibashi M.

ACS Chem Biol. 2018 Sep 21;13(9):2551-2559. doi: 10.1021/acschembio.8b00492. Epub 2018 Sep 7.

PMID:
30160475
16.

Acute peri-myocarditis with an unusual initial manifestation of gallbladder edema and a profound eosinophilic surge during convalescence.

Zenda T, Araki I, Nakamiya O, Ogawa M, Higashi K, Ueno T.

Fukushima J Med Sci. 2018;64(2):95-102. doi: 10.5387/fms.2018-08.

17.

Correlation between clinical and radiologic features of patients with Gerstmann-Sträussler-Scheinker syndrome (Pro102Leu).

Yoshimura M, Yuan JH, Higashi K, Yoshimura A, Arata H, Okubo R, Nakabeppu Y, Yoshiura T, Takashima H.

J Neurol Sci. 2018 Aug 15;391:15-21. doi: 10.1016/j.jns.2018.05.012. Epub 2018 May 17.

18.

Mechanism of Enhanced Nifedipine Dissolution by Polymer-Blended Solid Dispersion through Molecular-Level Characterization.

Ueda K, Yamazoe C, Yasuda Y, Higashi K, Kawakami K, Moribe K.

Mol Pharm. 2018 Sep 4;15(9):4099-4109. doi: 10.1021/acs.molpharmaceut.8b00523. Epub 2018 Aug 13.

PMID:
30064220
19.

Observation of Degradation of Pt and Carbon Support in Polymer Electrolyte Fuel Cell Using Combined Nano-X-ray Absorption Fine Structure and Transmission Electron Microscopy Techniques.

Takao S, Sekizawa O, Samjeské G, Kaneko T, Higashi K, Yoshida Y, Zhao X, Sakata T, Yamamoto T, Gunji T, Uruga T, Iwasawa Y.

ACS Appl Mater Interfaces. 2018 Aug 22;10(33):27734-27744. doi: 10.1021/acsami.8b04407. Epub 2018 Aug 13.

PMID:
30044074
20.

Perceived Hardness through Actual and Virtual Damped Natural Vibrations.

Higashi K, Okamoto S, Yamada Y.

IEEE Trans Haptics. 2018 Oct-Dec;11(4):646-651. doi: 10.1109/TOH.2018.2841820. Epub 2018 May 29.

PMID:
29993586
21.

A Novel SDHB IVS2-2A>C Mutation Is Responsible for Hereditary Pheochromocytoma/Paraganglioma Syndrome.

Yamanaka M, Shiga K, Fujiwara S, Mizuguchi Y, Yasuda S, Ishizawa K, Saiki Y, Higashi K, Ogawa T, Kimura N, Horii A.

Tohoku J Exp Med. 2018 Jun;245(2):99-105. doi: 10.1620/tjem.245.99.

22.

Latent environment allocation of microbial community data.

Higashi K, Suzuki S, Kurosawa S, Mori H, Kurokawa K.

PLoS Comput Biol. 2018 Jun 6;14(6):e1006143. doi: 10.1371/journal.pcbi.1006143. eCollection 2018 Jun.

23.

Protective Effects of Brain Infarction by N-Acetylcysteine Derivatives.

Uemura T, Watanabe K, Ko K, Higashi K, Kogure N, Kitajima M, Takayama H, Takao K, Sugita Y, Sakamoto A, Terui Y, Toida T, Kashiwagi K, Igarashi K.

Stroke. 2018 Jul;49(7):1727-1733. doi: 10.1161/STROKEAHA.118.021755. Epub 2018 Jun 4.

PMID:
29866754
24.

Combined effects of the drug distribution and mucus diffusion properties of self-microemulsifying drug delivery systems on the oral absorption of fenofibrate.

Sunazuka Y, Ueda K, Higashi K, Tanaka Y, Moribe K.

Int J Pharm. 2018 Jul 30;546(1-2):263-271. doi: 10.1016/j.ijpharm.2018.05.031. Epub 2018 May 26.

PMID:
29763688
25.

Annealing induced atomic rearrangements on (Ga,In) (N,As) probed by hard X-ray photoelectron spectroscopy and X-ray absorption fine structure.

Ishikawa F, Higashi K, Fuyuno S, Morifuji M, Kondow M, Trampert A.

Sci Rep. 2018 Apr 13;8(1):5962. doi: 10.1038/s41598-018-23941-y.

26.

Morphological and Physicochemical Evaluation of Two Distinct Glibenclamide/Hypromellose Amorphous Nanoparticles Prepared by the Antisolvent Method.

Yonashiro H, Higashi K, Morikawa C, Ueda K, Itoh T, Ito M, Masu H, Noguchi S, Moribe K.

Mol Pharm. 2018 Apr 2;15(4):1587-1597. doi: 10.1021/acs.molpharmaceut.7b01122. Epub 2018 Mar 12.

PMID:
29502422
27.

Cancer-Type OATP1B3 mRNA in Extracellular Vesicles as a Promising Candidate for a Serum-Based Colorectal Cancer Biomarker.

Morio H, Sun Y, Harada M, Ide H, Shimozato O, Zhou X, Higashi K, Yuki R, Yamaguchi N, Hofbauer JP, Guttmann-Gruber C, Anzai N, Akita H, Chiba K, Furihata T.

Biol Pharm Bull. 2018;41(3):445-449. doi: 10.1248/bpb.b17-00743.

28.

S1P-S1PR2 Axis Mediates Homing of Muse Cells Into Damaged Heart for Long-Lasting Tissue Repair and Functional Recovery After Acute Myocardial Infarction.

Yamada Y, Wakao S, Kushida Y, Minatoguchi S, Mikami A, Higashi K, Baba S, Shigemoto T, Kuroda Y, Kanamori H, Amin M, Kawasaki M, Nishigaki K, Taoka M, Isobe T, Muramatsu C, Dezawa M, Minatoguchi S.

Circ Res. 2018 Apr 13;122(8):1069-1083. doi: 10.1161/CIRCRESAHA.117.311648. Epub 2018 Feb 23.

PMID:
29475983
29.

Reduction of Spermidine Content Resulting from Inactivation of Two Arginine Decarboxylases Increases Biofilm Formation in Synechocystis sp. Strain PCC 6803.

Kera K, Nagayama T, Nanatani K, Saeki-Yamoto C, Tominaga A, Souma S, Miura N, Takeda K, Kayamori S, Ando E, Higashi K, Igarashi K, Uozumi N.

J Bacteriol. 2018 Apr 9;200(9). pii: e00664-17. doi: 10.1128/JB.00664-17. Print 2018 May 1.

30.

Simple laryngeal suspension procedure by suturing the digastric muscle to the periosteum of the mandible in neck dissection for tongue cancer.

Ohkoshi A, Ogawa T, Sagai S, Nakanome A, Higashi K, Ishii R, Kato K, Katori Y.

Am J Otolaryngol. 2018 Mar - Apr;39(2):77-81. doi: 10.1016/j.amjoto.2018.01.008. Epub 2018 Jan 31.

PMID:
29395281
31.

Comprehensive analysis of glycosaminoglycans from the edible shellfish.

Okamoto Y, Higashi K, Linhardt RJ, Toida T.

Carbohydr Polym. 2018 Mar 15;184:269-276. doi: 10.1016/j.carbpol.2017.12.076. Epub 2017 Dec 29.

PMID:
29352919
32.

Molecular-level elucidation of saccharin-assisted rapid dissolution and high supersaturation level of drug from Eudragit® E solid dispersion.

Ueda K, Kanaya H, Higashi K, Yamamoto K, Moribe K.

Int J Pharm. 2018 Mar 1;538(1-2):57-64. doi: 10.1016/j.ijpharm.2017.12.050. Epub 2018 Jan 16.

PMID:
29341907
33.

Effects of Inorganic Iodine Therapy Administered to Lactating Mothers With Graves Disease on Infant Thyroid Function.

Hamada K, Mizokami T, Maruta T, Higashi K, Konishi K, Momotani N, Tajiri J.

J Endocr Soc. 2017 Sep 19;1(10):1293-1300. doi: 10.1210/js.2017-00297. eCollection 2017 Oct 1.

34.

Nano-scale and molecular-level understanding of wet-milled indomethacin/poloxamer 407 nanosuspension with TEM, suspended-state NMR, and Raman measurements.

Kuroiwa Y, Higashi K, Ueda K, Yamamoto K, Moribe K.

Int J Pharm. 2018 Feb 15;537(1-2):30-39. doi: 10.1016/j.ijpharm.2017.12.028. Epub 2017 Dec 12.

PMID:
29246438
35.

Reappraising newborn screening for cobalamin C disorder.

Tocan V, Ohkubo K, Higashi K, Toda N, Kojima-Ishii K, Nishiyama K, Ishimura M, Takada H, Sakamoto O, Sasaki F, Yoshimura K, Hirose S, Ohga S.

Pediatr Neonatol. 2018 Aug;59(4):415-417. doi: 10.1016/j.pedneo.2017.11.002. Epub 2017 Nov 22. No abstract available.

36.

Sequencing the Dermatan Sulfate Chain of Decorin.

Yu Y, Duan J, Leach FE 3rd, Toida T, Higashi K, Zhang H, Zhang F, Amster IJ, Linhardt RJ.

J Am Chem Soc. 2017 Nov 22;139(46):16986-16995. doi: 10.1021/jacs.7b10164. Epub 2017 Nov 13.

37.

Determination of Nonspherical Morphology of Doxorubicin-Loaded Liposomes by Atomic Force Microscopy.

Takahashi N, Higashi K, Ueda K, Yamamoto K, Moribe K.

J Pharm Sci. 2018 Feb;107(2):717-726. doi: 10.1016/j.xphs.2017.10.009. Epub 2017 Oct 13.

PMID:
29031955
38.

Probucol prevents the attenuation of β2-adrenoceptor-mediated vasodilation of retinal arterioles in diabetic rats.

Mori A, Higashi K, Wakao S, Sakamoto K, Ishii K, Nakahara T.

Naunyn Schmiedebergs Arch Pharmacol. 2017 Dec;390(12):1247-1253. doi: 10.1007/s00210-017-1423-y. Epub 2017 Sep 14.

PMID:
28913547
39.

Editor's Highlight: Development of Novel Neural Embryonic Stem CellTests for High-Throughput Screening of Embryotoxic Chemicals.

Kobayashi K, Suzuki N, Higashi K, Muroi A, Le Coz F, Nagahori H, Saito K.

Toxicol Sci. 2017 Sep 1;159(1):238-250. doi: 10.1093/toxsci/kfx130.

PMID:
28903496
40.

Determination of 3-hydroxypropylmercapturic acid in urine by three column-switching high-performance liquid chromatography with electrochemical detection using a diamond electrode.

Higashi K, Shibasaki M, Kuni K, Uemura T, Waragai M, Uemura K, Igarashi K, Toida T.

J Chromatogr A. 2017 Sep 29;1517:79-85. doi: 10.1016/j.chroma.2017.08.030. Epub 2017 Aug 26.

PMID:
28851527
41.

Antidiabetic Drug Alogliptin Protects the Heart Against Ischemia-reperfusion Injury Through GLP-1 Receptor-dependent and Receptor-independent Pathways Involving Nitric Oxide Production in Rabbits.

Baba S, Iwasa M, Higashi K, Minatoguchi S, Yamada Y, Kanamori H, Kawasaki M, Nishigaki K, Minatoguchi S.

J Cardiovasc Pharmacol. 2017 Dec;70(6):382-389. doi: 10.1097/FJC.0000000000000531.

PMID:
28817485
42.

Pharmacokinetics and Safety of Brexpiprazole Following Multiple-Dose Administration to Japanese Patients With Schizophrenia.

Ishigooka J, Iwashita S, Higashi K, Liew EL, Tadori Y.

J Clin Pharmacol. 2018 Jan;58(1):74-80. doi: 10.1002/jcph.979. Epub 2017 Jul 27.

43.

High FDG uptake on PET is associated with negative cell-to-cell adhesion molecule E-cadherin expression in lung adenocarcinoma.

Higashi K, Ueda Y, Shimasaki M, Ishigaki Y, Nakamura Y, Oguchi M, Takegami T, Watanabe N.

Ann Nucl Med. 2017 Oct;31(8):590-595. doi: 10.1007/s12149-017-1187-y. Epub 2017 Jul 4.

PMID:
28677069
44.

Recovery from reproductive and morphological abnormalities in medaka (Oryzias latipes) following a 14-day exposure to diclofenac.

Yokota H, Higashi K, Hanada E, Matsuzaki E, Tsuruda Y, Suzuki T, Nakano E, Eguchi S.

Environ Toxicol Chem. 2017 Dec;36(12):3277-3283. doi: 10.1002/etc.3899. Epub 2017 Sep 14.

PMID:
28636229
45.

Operando 3D Visualization of Migration and Degradation of a Platinum Cathode Catalyst in a Polymer Electrolyte Fuel Cell.

Matsui H, Ishiguro N, Uruga T, Sekizawa O, Higashi K, Maejima N, Tada M.

Angew Chem Int Ed Engl. 2017 Aug 1;56(32):9371-9375. doi: 10.1002/anie.201703940. Epub 2017 Jul 6.

PMID:
28620952
46.

Direct NMR Monitoring of Phase Separation Behavior of Highly Supersaturated Nifedipine Solution Stabilized with Hypromellose Derivatives.

Ueda K, Higashi K, Moribe K.

Mol Pharm. 2017 Jul 3;14(7):2314-2322. doi: 10.1021/acs.molpharmaceut.7b00178. Epub 2017 Jun 6.

PMID:
28558250
47.

Heparan sulfate alterations in extracellular matrix structures and fibroblast growth factor-2 signaling impairment in the aged neurogenic niche.

Yamada T, Kerever A, Yoshimura Y, Suzuki Y, Nonaka R, Higashi K, Toida T, Mercier F, Arikawa-Hirasawa E.

J Neurochem. 2017 Aug;142(4):534-544. doi: 10.1111/jnc.14081. Epub 2017 Jun 20.

48.

Measuring hip flexor and extensor strengths across various postures using a fixed belt.

Yoshizawa T, Higashi K, Katou T.

J Phys Ther Sci. 2017 Apr;29(4):572-575. doi: 10.1589/jpts.29.572. Epub 2017 Apr 20.

49.

Effect of guest drug character encapsulated in the cavity and intermolecular spaces of γ-cyclodextrins on the dissolution property of ternary γ-cyclodextrin complex.

Liu N, Higashi K, Ueda K, Moribe K.

Int J Pharm. 2017 Oct 15;531(2):543-549. doi: 10.1016/j.ijpharm.2017.04.049. Epub 2017 Apr 24.

PMID:
28450165
50.

Effects of wet-granulation process parameters on the dissolution and physical stability of a solid dispersion.

Kinoshita R, Ohta T, Shiraki K, Higashi K, Moribe K.

Int J Pharm. 2017 May 30;524(1-2):304-311. doi: 10.1016/j.ijpharm.2017.04.007. Epub 2017 Apr 5.

PMID:
28389363

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