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Items: 1 to 50 of 56

1.

A longitudinal analysis of CA125 glycoforms in the monitoring and follow up of high grade serous ovarian cancer.

Salminen L, Nadeem N, Jain S, Grènman S, Carpén O, Hietanen S, Oksa S, Lamminmäki U, Pettersson K, Gidwani K, Huhtinen K, Hynninen J.

Gynecol Oncol. 2019 Dec 27. pii: S0090-8258(19)31846-3. doi: 10.1016/j.ygyno.2019.12.025. [Epub ahead of print]

2.

Virtual clinical trials identify effective combination therapies in ovarian cancer.

Kozłowska E, Vallius T, Hynninen J, Hietanen S, Färkkilä A, Hautaniemi S.

Sci Rep. 2019 Dec 10;9(1):18678. doi: 10.1038/s41598-019-55068-z.

3.

Vulvar malignant pleomorphic adenoma in a patient with lichen sclerosus.

Hieta NK, Kurki SH, Rintala MA, Söderlund JM, Hietanen SH, Katri OJ.

JAAD Case Rep. 2019 Oct 31;5(11):994-996. doi: 10.1016/j.jdcr.2019.09.013. eCollection 2019 Nov. No abstract available.

4.

Characteristics of subjects with alcoholic cardiomyopathy and sudden cardiac death.

Hietanen S, Herajärvi J, Junttila J, Pakanen L, Huikuri HV, Liisanantti J.

Heart. 2019 Sep 24. pii: heartjnl-2019-315534. doi: 10.1136/heartjnl-2019-315534. [Epub ahead of print]

PMID:
31551291
5.

Niraparib plus bevacizumab versus niraparib alone for platinum-sensitive recurrent ovarian cancer (NSGO-AVANOVA2/ENGOT-ov24): a randomised, phase 2, superiority trial.

Mirza MR, Åvall Lundqvist E, Birrer MJ, dePont Christensen R, Nyvang GB, Malander S, Anttila M, Werner TL, Lund B, Lindahl G, Hietanen S, Peen U, Dimoula M, Roed H, Ør Knudsen A, Staff S, Krog Vistisen A, Bjørge L, Mäenpää JU; AVANOVA investigators.

Lancet Oncol. 2019 Oct;20(10):1409-1419. doi: 10.1016/S1470-2045(19)30515-7. Epub 2019 Aug 29.

PMID:
31474354
6.

Open Source Infrastructure for Health Care Data Integration and Machine Learning Analyses.

Isoviita VM, Salminen L, Azar J, Lehtonen R, Roering P, Carpén O, Hietanen S, Grénman S, Hynninen J, Färkkilä A, Hautaniemi S.

JCO Clin Cancer Inform. 2019 Aug;3:1-16. doi: 10.1200/CCI.18.00132.

7.

Behavior of FDG-avid supradiaphragmatic lymph nodes in PET/CT throughout primary therapy in advanced serous epithelial ovarian cancer: a prospective study.

Laasik M, Kemppainen J, Auranen A, Hietanen S, Grénman S, Seppänen M, Hynninen J.

Cancer Imaging. 2019 May 29;19(1):27. doi: 10.1186/s40644-019-0215-7.

8.

Decorin Expression in Human Vulva Carcinoma: Oncosuppressive Effect of Decorin cDNA Transduction on Carcinoma Cells.

Nyman MC, Jokilammi AB, Boström PC, Kurki SH, Sainio AO, Grenman SE, Orte KJ, Hietanen SH, Elenius K, Järveläinen HT.

J Histochem Cytochem. 2019 Jul;67(7):511-522. doi: 10.1369/0022155419845373. Epub 2019 Apr 22.

PMID:
31009269
9.

Time to go functional! Determining tumors' DNA repair capacity ex vivo.

Tumiati M, Hietanen S, Kauppi L.

Oncotarget. 2018 Dec 7;9(96):36826-36827. doi: 10.18632/oncotarget.26419. eCollection 2018 Dec 7. No abstract available.

10.

Association of Vulvar Melanoma with Lichen Sclerosus.

Hieta N, Kurki S, Rintala M, Söderlund J, Hietanen S, Orte K.

Acta Derm Venereol. 2019 Mar 1;99(3):339-340. doi: 10.2340/00015555-3103. No abstract available.

11.

Identifying differentially methylated sites in samples with varying tumor purity.

Häkkinen A, Alkodsi A, Facciotto C, Zhang K, Kaipio K, Leppä S, Carpén O, Grénman S, Hynninen J, Hietanen S, Lehtonen R, Hautaniemi S.

Bioinformatics. 2018 Sep 15;34(18):3078-3085. doi: 10.1093/bioinformatics/bty310.

PMID:
29912358
12.

A Functional Homologous Recombination Assay Predicts Primary Chemotherapy Response and Long-Term Survival in Ovarian Cancer Patients.

Tumiati M, Hietanen S, Hynninen J, Pietilä E, Färkkilä A, Kaipio K, Roering P, Huhtinen K, Alkodsi A, Li Y, Lehtonen R, Erkan EP, Tuominen MM, Lehti K, Hautaniemi SK, Vähärautio A, Grénman S, Carpén O, Kauppi L.

Clin Cancer Res. 2018 Sep 15;24(18):4482-4493. doi: 10.1158/1078-0432.CCR-17-3770. Epub 2018 Jun 1.

13.

Mathematical Modeling Predicts Response to Chemotherapy and Drug Combinations in Ovarian Cancer.

Kozłowska E, Färkkilä A, Vallius T, Carpén O, Kemppainen J, Grénman S, Lehtonen R, Hynninen J, Hietanen S, Hautaniemi S.

Cancer Res. 2018 Jul 15;78(14):4036-4044. doi: 10.1158/0008-5472.CAN-17-3746. Epub 2018 May 16.

14.

Treatment Profile and 1-Year Mortality Among Nontraumatic Intensive Care Unit Patients With Alcohol-Related Health Problems.

Hietanen S, Ala-Kokko T, Ohtonen P, Käkelä R, Niemelä S, Liisanantti JH.

J Intensive Care Med. 2017 Jan 1:885066617740071. doi: 10.1177/0885066617740071. [Epub ahead of print]

PMID:
29105539
15.

Has the income of the residential area impact on the use of intensive care?

Liisanantti JH, Käkelä R, Raatiniemi LV, Ohtonen P, Hietanen S, Ala-Kokko TI.

Acta Anaesthesiol Scand. 2017 Aug;61(7):804-812. doi: 10.1111/aas.12933. Epub 2017 Jun 26.

PMID:
28653376
16.

Aeration-Induced Changes in Temperature and Nitrogen Dynamics in a Dimictic Lake.

Holmroos H, Horppila J, Laakso S, Niemistö J, Hietanen S.

J Environ Qual. 2016 Jul;45(4):1359-66. doi: 10.2134/jeq2015.09.0455.

PMID:
27380085
17.

Spatial and temporal dynamics of ammonia oxidizers in the sediments of the Gulf of Finland, Baltic Sea.

Vetterli A, Hietanen S, Leskinen E.

Mar Environ Res. 2016 Feb;113:153-63. doi: 10.1016/j.marenvres.2015.12.008. Epub 2015 Dec 15.

PMID:
26722795
18.

N and O isotope fractionation in nitrate during chemolithoautotrophic denitrification by Sulfurimonas gotlandica.

Frey C, Hietanen S, Jürgens K, Labrenz M, Voss M.

Environ Sci Technol. 2014 Nov 18;48(22):13229-37. doi: 10.1021/es503456g. Epub 2014 Nov 5.

PMID:
25347214
19.

Inhibition of c-Abl kinase activity renders cancer cells highly sensitive to mitoxantrone.

Alpay K, Farshchian M, Tuomela J, Sandholm J, Aittokallio K, Siljamäki E, Kallio M, Kähäri VM, Hietanen S.

PLoS One. 2014 Aug 22;9(8):e105526. doi: 10.1371/journal.pone.0105526. eCollection 2014.

20.

Novel action modality of the diterpenoid anisomelic acid causes depletion of E6 and E7 viral oncoproteins in HPV-transformed cervical carcinoma cells.

Paul P, Rajendran SK, Peuhu E, Alshatwi AA, Akbarsha MA, Hietanen S, Eriksson JE.

Biochem Pharmacol. 2014 May 15;89(2):171-84. doi: 10.1016/j.bcp.2014.02.011. Epub 2014 Feb 22.

PMID:
24565908
21.

Hypoxia in the Baltic Sea: biogeochemical cycles, benthic fauna, and management.

Carstensen J, Conley DJ, Bonsdorff E, Gustafsson BG, Hietanen S, Janas U, Jilbert T, Maximov A, Norkko A, Norkko J, Reed DC, Slomp CP, Timmermann K, Voss M.

Ambio. 2014 Feb;43(1):26-36. doi: 10.1007/s13280-013-0474-7.

22.

The role of recurrent disturbances for ecosystem multifunctionality.

Villnäs A, Norkko J, Hietanen S, Josefson AB, Lukkari K, Norkko A.

Ecology. 2013 Oct;94(10):2275-87.

PMID:
24358713
23.

Biogeochemistry: The depths of nitrogen cycling.

Voss M, Hietanen S.

Nature. 2013 Jan 31;493(7434):616-8. doi: 10.1038/493616a. No abstract available.

PMID:
23364738
24.

[Update on current care guidelines: ovarian cancer].

Leminen A, Auranen A, Bützow R, Hietanen S, Komulainen M, Kuoppala T, Mäenpää J, Puistola U, Vuento M, Vuorela P, Yliskoski M.

Duodecim. 2012;128(12):1300-1. Review. Finnish.

PMID:
22822606
25.

Measuring nitrification in sediments--comparison of two techniques and three 15NO(-)3 measurement methods.

Jäntti H, Leskinen E, Stange CF, Hietanen S.

Isotopes Environ Health Stud. 2012 Jun;48(2):313-26. doi: 10.1080/10256016.2012.641543. Epub 2012 Jan 30.

PMID:
22288425
26.

The effects of hypoxia on sediment nitrogen cycling in the Baltic Sea.

Jäntti H, Hietanen S.

Ambio. 2012 Mar;41(2):161-9. doi: 10.1007/s13280-011-0233-6. Epub 2012 Jan 14.

27.

Hypoxia-related processes in the Baltic Sea.

Conley DJ, Björck S, Bonsdorff E, Carstensen J, Destouni G, Gustafsson BG, Hietanen S, Kortekaas M, Kuosa H, Meier HE, Müller-Karulis B, Nordberg K, Norkko A, Nürnberg G, Pitkänen H, Rabalais NN, Rosenberg R, Savchuk OP, Slomp CP, Voss M, Wulff F, Zillén L.

Environ Sci Technol. 2009 May 15;43(10):3412-20. Review.

PMID:
19544833
28.

Denitrification in the river estuaries of the northern Baltic Sea.

Silvennoinen H, Hietanen S, Liikanen A, Stange CF, Russow R, Kuparinen J, Martikainen PJ.

Ambio. 2007 Apr;36(2-3):134-40.

PMID:
17520925
30.

Community structure of the bacteria associated with Nodularia sp. (Cyanobacteria) aggregates in the Baltic Sea.

Tuomainen J, Hietanen S, Kuparinen J, Martikainen PJ, Servomaa K.

Microb Ecol. 2006 Oct;52(3):513-22. Epub 2006 Aug 31.

PMID:
16944338
31.

Hormonal treatments and epithelial ovarian cancer risk.

Auranen A, Hietanen S, Salmi T, Grénman S.

Int J Gynecol Cancer. 2005 Sep-Oct;15(5):692-700. Review.

32.

DNA topoisomerase I is a cofactor for c-Jun in the regulation of epidermal growth factor receptor expression and cancer cell proliferation.

Mialon A, Sankinen M, Söderström H, Junttila TT, Holmström T, Koivusalo R, Papageorgiou AC, Johnson RS, Hietanen S, Elenius K, Westermarck J.

Mol Cell Biol. 2005 Jun;25(12):5040-51.

34.

The cytotoxicity of chemotherapy drugs varies in cervical cancer cells depending on the p53 status.

Koivusalo R, Hietanen S.

Cancer Biol Ther. 2004 Nov;3(11):1177-83. Epub 2004 Nov 1.

PMID:
15640620
35.

Hysterectomy for gynaecological cancer: a follow-up study of subjective and objective outcome.

Meltomaa SS, Hietanen SH, Taalikka MO, Haarala MA, Kiilholma PJ, Mäkinen JI.

Aust N Z J Obstet Gynaecol. 2004 Jun;44(3):214-21.

PMID:
15191445
36.

Response of estrogen receptor-positive intraabdominal fibromatosis to aromatase inhibitor therapy.

Klemi P, Alanen K, Hietanen S, Grénman S, Varpula M, Salmi T.

Obstet Gynecol. 2003 Nov;102(5 Pt 2):1155-8.

PMID:
14607040
37.

Baltic Sea cyanobacterial bloom contains denitrification and nitrification genes, but has negligible denitrification activity.

Tuomainen JM, Hietanen S, Kuparinen J, Martikainen PJ, Servomaa K.

FEMS Microbiol Ecol. 2003 Jul 1;45(2):83-96. doi: 10.1016/S0168-6496(03)00131-4.

38.
39.

[An agitated psychotic patient].

Hietanen S, Henriksson M.

Duodecim. 2002;118(3):279-84. Review. Finnish. No abstract available.

PMID:
12233029
40.

Mutations of TP53 do not correlate with the sensitivity to paclitaxel--a study using 27 gynaecological cancer cell lines.

Rantanen V, Engblom P, Raitanen M, Hietanen S, Haarala M, Grénman S, Syrjänen S.

Eur J Cancer. 2002 Sep;38(13):1783-91.

PMID:
12175696
41.

Single copy heterozygote integration of HPV 33 in chromosomal band 5p14 is found in an epithelial cell clone with selective growth advantage.

Peitsaro P, Hietanen S, Johansson B, Lakkala T, Syrjänen S.

Carcinogenesis. 2002 Jun;23(6):1057-64.

PMID:
12082029
42.

Activation of p53 in cervical carcinoma cells by small molecules.

Hietanen S, Lain S, Krausz E, Blattner C, Lane DP.

Proc Natl Acad Sci U S A. 2000 Jul 18;97(15):8501-6.

43.

Expression of cell-cycle proteins p53, p21 (WAF-1), PCNA and Ki-67 in benign, premalignant and malignant skin lesions with implicated HPV involvement.

Lu S, Tiekso J, Hietanen S, Syrjänen K, Havu VK, Syrjänen S.

Acta Derm Venereol. 1999 Jul;79(4):268-73.

44.

Collagenase-3 (MMP-13) is expressed by tumor cells in invasive vulvar squamous cell carcinomas.

Johansson N, Vaalamo M, Grénman S, Hietanen S, Klemi P, Saarialho-Kere U, Kähäri VM.

Am J Pathol. 1999 Feb;154(2):469-80.

45.

p53 mutations and presence of HPV DNA do not correlate with radiosensitivity of gynecological cancer cell lines.

Rantanen V, Grénman S, Kurvinen K, Hietanen S, Raitanen M, Syrjänen S.

Gynecol Oncol. 1998 Dec;71(3):352-8.

PMID:
9887230
46.
47.

Human papillomavirus type 33 DNA and E6-E7 transcripts in late passages of the UT-DEC-1 vaginal keratinocyte cell line.

Auvinen E, Hietanen S, Gissmann L, Alonso A.

Mol Cell Probes. 1998 Feb;12(1):59-62.

PMID:
9584080
49.

Type I diabetic pregnancy and subclinical human papillomavirus infection.

Hietanen S, Ekblad U, Pelliniemi TT, Syrjänen K, Helenius H, Syrjänen S.

Clin Infect Dis. 1997 Feb;24(2):153-6.

PMID:
9114140
50.

[A dissociative disorder or a psychosis?].

Hietanen S.

Duodecim. 1997;113(15):1497-8. Finnish. No abstract available.

PMID:
10643127

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