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Items: 46

1.

Identifying differentially methylated sites in samples with varying tumor purity.

Häkkinen A, Alkodsi A, Facciotto C, Zhang K, Kaipio K, Leppä S, Carpén O, Grénman S, Hynninen J, Hietanen S, Lehtonen R, Hautaniemi S.

Bioinformatics. 2018 Sep 15;34(18):3078-3085. doi: 10.1093/bioinformatics/bty310.

PMID:
29912358
2.

A Functional Homologous Recombination Assay Predicts Primary Chemotherapy Response and Long-Term Survival in Ovarian Cancer Patients.

Tumiati M, Hietanen S, Hynninen J, Pietilä E, Färkkilä A, Kaipio K, Roering P, Huhtinen K, Alkodsi A, Li Y, Lehtonen R, Erkan EP, Tuominen MM, Lehti K, Hautaniemi SK, Vähärautio A, Grénman S, Carpén O, Kauppi L.

Clin Cancer Res. 2018 Sep 15;24(18):4482-4493. doi: 10.1158/1078-0432.CCR-17-3770. Epub 2018 Jun 1.

PMID:
29858219
3.

Mathematical Modeling Predicts Response to Chemotherapy and Drug Combinations in Ovarian Cancer.

Kozłowska E, Färkkilä A, Vallius T, Carpén O, Kemppainen J, Grénman S, Lehtonen R, Hynninen J, Hietanen S, Hautaniemi S.

Cancer Res. 2018 Jul 15;78(14):4036-4044. doi: 10.1158/0008-5472.CAN-17-3746. Epub 2018 May 16.

PMID:
29769198
4.

Treatment Profile and 1-Year Mortality Among Nontraumatic Intensive Care Unit Patients With Alcohol-Related Health Problems.

Hietanen S, Ala-Kokko T, Ohtonen P, Käkelä R, Niemelä S, Liisanantti JH.

J Intensive Care Med. 2017 Jan 1:885066617740071. doi: 10.1177/0885066617740071. [Epub ahead of print]

PMID:
29105539
5.

Has the income of the residential area impact on the use of intensive care?

Liisanantti JH, Käkelä R, Raatiniemi LV, Ohtonen P, Hietanen S, Ala-Kokko TI.

Acta Anaesthesiol Scand. 2017 Aug;61(7):804-812. doi: 10.1111/aas.12933. Epub 2017 Jun 26.

PMID:
28653376
6.

Aeration-Induced Changes in Temperature and Nitrogen Dynamics in a Dimictic Lake.

Holmroos H, Horppila J, Laakso S, Niemistö J, Hietanen S.

J Environ Qual. 2016 Jul;45(4):1359-66. doi: 10.2134/jeq2015.09.0455.

PMID:
27380085
7.

Spatial and temporal dynamics of ammonia oxidizers in the sediments of the Gulf of Finland, Baltic Sea.

Vetterli A, Hietanen S, Leskinen E.

Mar Environ Res. 2016 Feb;113:153-63. doi: 10.1016/j.marenvres.2015.12.008. Epub 2015 Dec 15.

PMID:
26722795
8.

N and O isotope fractionation in nitrate during chemolithoautotrophic denitrification by Sulfurimonas gotlandica.

Frey C, Hietanen S, Jürgens K, Labrenz M, Voss M.

Environ Sci Technol. 2014 Nov 18;48(22):13229-37. doi: 10.1021/es503456g. Epub 2014 Nov 5.

PMID:
25347214
9.

Inhibition of c-Abl kinase activity renders cancer cells highly sensitive to mitoxantrone.

Alpay K, Farshchian M, Tuomela J, Sandholm J, Aittokallio K, Siljamäki E, Kallio M, Kähäri VM, Hietanen S.

PLoS One. 2014 Aug 22;9(8):e105526. doi: 10.1371/journal.pone.0105526. eCollection 2014.

10.

Novel action modality of the diterpenoid anisomelic acid causes depletion of E6 and E7 viral oncoproteins in HPV-transformed cervical carcinoma cells.

Paul P, Rajendran SK, Peuhu E, Alshatwi AA, Akbarsha MA, Hietanen S, Eriksson JE.

Biochem Pharmacol. 2014 May 15;89(2):171-84. doi: 10.1016/j.bcp.2014.02.011. Epub 2014 Feb 22.

PMID:
24565908
11.

Hypoxia in the Baltic Sea: biogeochemical cycles, benthic fauna, and management.

Carstensen J, Conley DJ, Bonsdorff E, Gustafsson BG, Hietanen S, Janas U, Jilbert T, Maximov A, Norkko A, Norkko J, Reed DC, Slomp CP, Timmermann K, Voss M.

Ambio. 2014 Feb;43(1):26-36. doi: 10.1007/s13280-013-0474-7.

12.

The role of recurrent disturbances for ecosystem multifunctionality.

Villnäs A, Norkko J, Hietanen S, Josefson AB, Lukkari K, Norkko A.

Ecology. 2013 Oct;94(10):2275-87.

PMID:
24358713
13.

Biogeochemistry: The depths of nitrogen cycling.

Voss M, Hietanen S.

Nature. 2013 Jan 31;493(7434):616-8. doi: 10.1038/493616a. No abstract available.

PMID:
23364738
14.

[Update on current care guidelines: ovarian cancer].

Leminen A, Auranen A, Bützow R, Hietanen S, Komulainen M, Kuoppala T, Mäenpää J, Puistola U, Vuento M, Vuorela P, Yliskoski M.

Duodecim. 2012;128(12):1300-1. Review. Finnish.

PMID:
22822606
15.

Measuring nitrification in sediments--comparison of two techniques and three 15NO(-)3 measurement methods.

Jäntti H, Leskinen E, Stange CF, Hietanen S.

Isotopes Environ Health Stud. 2012 Jun;48(2):313-26. doi: 10.1080/10256016.2012.641543. Epub 2012 Jan 30.

PMID:
22288425
16.

The effects of hypoxia on sediment nitrogen cycling in the Baltic Sea.

Jäntti H, Hietanen S.

Ambio. 2012 Mar;41(2):161-9. doi: 10.1007/s13280-011-0233-6. Epub 2012 Jan 14.

17.

Hypoxia-related processes in the Baltic Sea.

Conley DJ, Björck S, Bonsdorff E, Carstensen J, Destouni G, Gustafsson BG, Hietanen S, Kortekaas M, Kuosa H, Meier HE, Müller-Karulis B, Nordberg K, Norkko A, Nürnberg G, Pitkänen H, Rabalais NN, Rosenberg R, Savchuk OP, Slomp CP, Voss M, Wulff F, Zillén L.

Environ Sci Technol. 2009 May 15;43(10):3412-20. Review.

PMID:
19544833
18.

Denitrification in the river estuaries of the northern Baltic Sea.

Silvennoinen H, Hietanen S, Liikanen A, Stange CF, Russow R, Kuparinen J, Martikainen PJ.

Ambio. 2007 Apr;36(2-3):134-40.

PMID:
17520925
20.

Community structure of the bacteria associated with Nodularia sp. (Cyanobacteria) aggregates in the Baltic Sea.

Tuomainen J, Hietanen S, Kuparinen J, Martikainen PJ, Servomaa K.

Microb Ecol. 2006 Oct;52(3):513-22. Epub 2006 Aug 31.

PMID:
16944338
21.

Hormonal treatments and epithelial ovarian cancer risk.

Auranen A, Hietanen S, Salmi T, Grénman S.

Int J Gynecol Cancer. 2005 Sep-Oct;15(5):692-700. Review.

PMID:
16174215
22.

DNA topoisomerase I is a cofactor for c-Jun in the regulation of epidermal growth factor receptor expression and cancer cell proliferation.

Mialon A, Sankinen M, Söderström H, Junttila TT, Holmström T, Koivusalo R, Papageorgiou AC, Johnson RS, Hietanen S, Elenius K, Westermarck J.

Mol Cell Biol. 2005 Jun;25(12):5040-51.

24.

The cytotoxicity of chemotherapy drugs varies in cervical cancer cells depending on the p53 status.

Koivusalo R, Hietanen S.

Cancer Biol Ther. 2004 Nov;3(11):1177-83. Epub 2004 Nov 1.

PMID:
15640620
25.

Hysterectomy for gynaecological cancer: a follow-up study of subjective and objective outcome.

Meltomaa SS, Hietanen SH, Taalikka MO, Haarala MA, Kiilholma PJ, Mäkinen JI.

Aust N Z J Obstet Gynaecol. 2004 Jun;44(3):214-21.

PMID:
15191445
26.

Response of estrogen receptor-positive intraabdominal fibromatosis to aromatase inhibitor therapy.

Klemi P, Alanen K, Hietanen S, Grénman S, Varpula M, Salmi T.

Obstet Gynecol. 2003 Nov;102(5 Pt 2):1155-8.

PMID:
14607040
27.

Baltic Sea cyanobacterial bloom contains denitrification and nitrification genes, but has negligible denitrification activity.

Tuomainen JM, Hietanen S, Kuparinen J, Martikainen PJ, Servomaa K.

FEMS Microbiol Ecol. 2003 Jul 1;45(2):83-96. doi: 10.1016/S0168-6496(03)00131-4.

28.
29.

[An agitated psychotic patient].

Hietanen S, Henriksson M.

Duodecim. 2002;118(3):279-84. Review. Finnish. No abstract available.

PMID:
12233029
30.

Mutations of TP53 do not correlate with the sensitivity to paclitaxel--a study using 27 gynaecological cancer cell lines.

Rantanen V, Engblom P, Raitanen M, Hietanen S, Haarala M, Grénman S, Syrjänen S.

Eur J Cancer. 2002 Sep;38(13):1783-91.

PMID:
12175696
31.

Single copy heterozygote integration of HPV 33 in chromosomal band 5p14 is found in an epithelial cell clone with selective growth advantage.

Peitsaro P, Hietanen S, Johansson B, Lakkala T, Syrjänen S.

Carcinogenesis. 2002 Jun;23(6):1057-64.

PMID:
12082029
32.

Activation of p53 in cervical carcinoma cells by small molecules.

Hietanen S, Lain S, Krausz E, Blattner C, Lane DP.

Proc Natl Acad Sci U S A. 2000 Jul 18;97(15):8501-6.

33.

Expression of cell-cycle proteins p53, p21 (WAF-1), PCNA and Ki-67 in benign, premalignant and malignant skin lesions with implicated HPV involvement.

Lu S, Tiekso J, Hietanen S, Syrjänen K, Havu VK, Syrjänen S.

Acta Derm Venereol. 1999 Jul;79(4):268-73.

PMID:
10429981
34.

Collagenase-3 (MMP-13) is expressed by tumor cells in invasive vulvar squamous cell carcinomas.

Johansson N, Vaalamo M, Grénman S, Hietanen S, Klemi P, Saarialho-Kere U, Kähäri VM.

Am J Pathol. 1999 Feb;154(2):469-80.

35.

p53 mutations and presence of HPV DNA do not correlate with radiosensitivity of gynecological cancer cell lines.

Rantanen V, Grénman S, Kurvinen K, Hietanen S, Raitanen M, Syrjänen S.

Gynecol Oncol. 1998 Dec;71(3):352-8.

PMID:
9887230
36.
37.

Human papillomavirus type 33 DNA and E6-E7 transcripts in late passages of the UT-DEC-1 vaginal keratinocyte cell line.

Auvinen E, Hietanen S, Gissmann L, Alonso A.

Mol Cell Probes. 1998 Feb;12(1):59-62.

PMID:
9584080
39.

Type I diabetic pregnancy and subclinical human papillomavirus infection.

Hietanen S, Ekblad U, Pelliniemi TT, Syrjänen K, Helenius H, Syrjänen S.

Clin Infect Dis. 1997 Feb;24(2):153-6.

PMID:
9114140
40.

[A dissociative disorder or a psychosis?].

Hietanen S.

Duodecim. 1997;113(15):1497-8. Finnish. No abstract available.

PMID:
10643127
41.

[Catatonia].

Hietanen S, Henriksson M, Leppävuori A.

Duodecim. 1996;112(21):1989-98. Review. Finnish. No abstract available.

PMID:
10605199
42.

Mutation of tumor suppressor gene p53 is frequently found in vulvar carcinoma cells.

Hietanen SH, Kurvinen K, Syrjänen K, Grénman S, Carey T, McClatchey K, Syrjänen S.

Am J Obstet Gynecol. 1995 Nov;173(5):1477-82.

PMID:
7503188
43.

Human papillomavirus in vulvar and vaginal carcinoma cell lines.

Hietanen S, Grénman S, Syrjänen K, Lappalainen K, Kauppinen J, Carey T, Syrjänen S.

Br J Cancer. 1995 Jul;72(1):134-9. Erratum in: Br J Cancer 1995 Nov;72(5):1338.

44.
45.

[Hallucination as a conversion symptom].

Hietanen S.

Duodecim. 1994;110(9):918-9. Finnish. No abstract available.

PMID:
7588135
46.

Isolation of two keratinocyte cell lines derived from HPV-positive dysplastic vaginal lesions.

Hietanen S, Auvinen E, Grénman S, Lakkala T, Sajantila A, Klemi P, Mäenpää J.

Int J Cancer. 1992 Sep 30;52(3):391-8.

PMID:
1328068

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