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Items: 35

1.

Aberrant Expression of ERG Promotes Resistance to Combined PI3K and AR Pathway Inhibition through Maintenance of AR Target Genes.

Mao N, Gao D, Hu W, Hieronymus H, Wang S, Lee YS, Lee C, Choi D, Gopalan A, Chen Y, Carver BS.

Mol Cancer Ther. 2019 Sep;18(9):1577-1586. doi: 10.1158/1535-7163.MCT-18-1386. Epub 2019 Jul 11.

PMID:
31296553
2.

Tumor copy number alteration burden is a pan-cancer prognostic factor associated with recurrence and death.

Hieronymus H, Murali R, Tin A, Yadav K, Abida W, Moller H, Berney D, Scher H, Carver B, Scardino P, Schultz N, Taylor B, Vickers A, Cuzick J, Sawyers CL.

Elife. 2018 Sep 4;7. pii: e37294. doi: 10.7554/eLife.37294.

3.

Correction: Prostate-specific membrane antigen cleavage of vitamin B9 stimulates oncogenic signaling through metabotropic glutamate receptors.

Kaittanis C, Andreou C, Hieronymus H, Mao N, Foss CA, Eiber M, Weirich G, Panchal P, Gopalan A, Zurita J, Achilefu S, Chiosis G, Ponomarev V, Schwaiger M, Carver BS, Pomper MG, Grimm J.

J Exp Med. 2018 Jan 2;215(1):377. doi: 10.1084/jem.2017105211212017c. Epub 2017 Nov 28. No abstract available.

4.

Prostate-specific membrane antigen cleavage of vitamin B9 stimulates oncogenic signaling through metabotropic glutamate receptors.

Kaittanis C, Andreou C, Hieronymus H, Mao N, Foss CA, Eiber M, Weirich G, Panchal P, Gopalan A, Zurita J, Achilefu S, Chiosis G, Ponomarev V, Schwaiger M, Carver BS, Pomper MG, Grimm J.

J Exp Med. 2018 Jan 2;215(1):159-175. doi: 10.1084/jem.20171052. Epub 2017 Nov 15. Erratum in: J Exp Med. 2017 Nov 28;:.

5.

Deletion of 3p13-14 locus spanning FOXP1 to SHQ1 cooperates with PTEN loss in prostate oncogenesis.

Hieronymus H, Iaquinta PJ, Wongvipat J, Gopalan A, Murali R, Mao N, Carver BS, Sawyers CL.

Nat Commun. 2017 Oct 20;8(1):1081. doi: 10.1038/s41467-017-01198-9.

6.

Low CD38 Identifies Progenitor-like Inflammation-Associated Luminal Cells that Can Initiate Human Prostate Cancer and Predict Poor Outcome.

Liu X, Grogan TR, Hieronymus H, Hashimoto T, Mottahedeh J, Cheng D, Zhang L, Huang K, Stoyanova T, Park JW, Shkhyan RO, Nowroozizadeh B, Rettig MB, Sawyers CL, Elashoff D, Horvath S, Huang J, Witte ON, Goldstein AS.

Cell Rep. 2016 Dec 6;17(10):2596-2606. doi: 10.1016/j.celrep.2016.11.010.

7.

Identifying actionable targets through integrative analyses of GEM model and human prostate cancer genomic profiling.

Wanjala J, Taylor BS, Chapinski C, Hieronymus H, Wongvipat J, Chen Y, Nanjangud GJ, Schultz N, Xie Y, Liu S, Lu W, Yang Q, Sander C, Chen Z, Sawyers CL, Carver BS.

Mol Cancer Ther. 2015 Jan;14(1):278-88. doi: 10.1158/1535-7163.MCT-14-0542-T. Epub 2014 Nov 7.

8.

Copy number alteration burden predicts prostate cancer relapse.

Hieronymus H, Schultz N, Gopalan A, Carver BS, Chang MT, Xiao Y, Heguy A, Huberman K, Bernstein M, Assel M, Murali R, Vickers A, Scardino PT, Sander C, Reuter V, Taylor BS, Sawyers CL.

Proc Natl Acad Sci U S A. 2014 Jul 29;111(30):11139-44. doi: 10.1073/pnas.1411446111. Epub 2014 Jul 14.

9.

SPOP mutations in prostate cancer across demographically diverse patient cohorts.

Blattner M, Lee DJ, O'Reilly C, Park K, MacDonald TY, Khani F, Turner KR, Chiu YL, Wild PJ, Dolgalev I, Heguy A, Sboner A, Ramazangolu S, Hieronymus H, Sawyers C, Tewari AK, Moch H, Yoon GS, Known YC, Andrén O, Fall K, Demichelis F, Mosquera JM, Robinson BD, Barbieri CE, Rubin MA.

Neoplasia. 2014 Jan;16(1):14-20.

10.

Androgen receptor signaling regulates DNA repair in prostate cancers.

Polkinghorn WR, Parker JS, Lee MX, Kass EM, Spratt DE, Iaquinta PJ, Arora VK, Yen WF, Cai L, Zheng D, Carver BS, Chen Y, Watson PA, Shah NP, Fujisawa S, Goglia AG, Gopalan A, Hieronymus H, Wongvipat J, Scardino PT, Zelefsky MJ, Jasin M, Chaudhuri J, Powell SN, Sawyers CL.

Cancer Discov. 2013 Nov;3(11):1245-53. doi: 10.1158/2159-8290.CD-13-0172. Epub 2013 Sep 11.

11.

Traversing the genomic landscape of prostate cancer from diagnosis to death.

Hieronymus H, Sawyers CL.

Nat Genet. 2012 May 29;44(6):613-4. doi: 10.1038/ng.2301.

PMID:
22641202
12.

Modulators of prostate cancer cell proliferation and viability identified by short-hairpin RNA library screening.

Dahlman KB, Parker JS, Shamu T, Hieronymus H, Chapinski C, Carver B, Chang K, Hannon GJ, Sawyers CL.

PLoS One. 2012;7(4):e34414. doi: 10.1371/journal.pone.0034414. Epub 2012 Apr 11.

13.

Ultrasound and microstructures--a promising combination?

Hübner S, Kressirer S, Kralisch D, Bludszuweit-Philipp C, Lukow K, Jänich I, Schilling A, Hieronymus H, Liebner C, Jähnisch K.

ChemSusChem. 2012 Feb 13;5(2):279-88. doi: 10.1002/cssc.201100369.

PMID:
22337650
14.

A public genome-scale lentiviral expression library of human ORFs.

Yang X, Boehm JS, Yang X, Salehi-Ashtiani K, Hao T, Shen Y, Lubonja R, Thomas SR, Alkan O, Bhimdi T, Green TM, Johannessen CM, Silver SJ, Nguyen C, Murray RR, Hieronymus H, Balcha D, Fan C, Lin C, Ghamsari L, Vidal M, Hahn WC, Hill DE, Root DE.

Nat Methods. 2011 Jun 26;8(8):659-61. doi: 10.1038/nmeth.1638.

15.

Reciprocal feedback regulation of PI3K and androgen receptor signaling in PTEN-deficient prostate cancer.

Carver BS, Chapinski C, Wongvipat J, Hieronymus H, Chen Y, Chandarlapaty S, Arora VK, Le C, Koutcher J, Scher H, Scardino PT, Rosen N, Sawyers CL.

Cancer Cell. 2011 May 17;19(5):575-86. doi: 10.1016/j.ccr.2011.04.008.

16.

FAS and NF-κB signalling modulate dependence of lung cancers on mutant EGFR.

Bivona TG, Hieronymus H, Parker J, Chang K, Taron M, Rosell R, Moonsamy P, Dahlman K, Miller VA, Costa C, Hannon G, Sawyers CL.

Nature. 2011 Mar 24;471(7339):523-6. doi: 10.1038/nature09870.

17.

MYC cooperates with AKT in prostate tumorigenesis and alters sensitivity to mTOR inhibitors.

Clegg NJ, Couto SS, Wongvipat J, Hieronymus H, Carver BS, Taylor BS, Ellwood-Yen K, Gerald WL, Sander C, Sawyers CL.

PLoS One. 2011 Mar 4;6(3):e17449. doi: 10.1371/journal.pone.0017449.

18.

COT drives resistance to RAF inhibition through MAP kinase pathway reactivation.

Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA, Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM, Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA.

Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627. Epub 2010 Nov 24.

19.

Integrative genomic profiling of human prostate cancer.

Taylor BS, Schultz N, Hieronymus H, Gopalan A, Xiao Y, Carver BS, Arora VK, Kaushik P, Cerami E, Reva B, Antipin Y, Mitsiades N, Landers T, Dolgalev I, Major JE, Wilson M, Socci ND, Lash AE, Heguy A, Eastham JA, Scher HI, Reuter VE, Scardino PT, Sander C, Sawyers CL, Gerald WL.

Cancer Cell. 2010 Jul 13;18(1):11-22. doi: 10.1016/j.ccr.2010.05.026. Epub 2010 Jun 24.

20.

Cooperativity of TMPRSS2-ERG with PI3-kinase pathway activation in prostate oncogenesis.

King JC, Xu J, Wongvipat J, Hieronymus H, Carver BS, Leung DH, Taylor BS, Sander C, Cardiff RD, Couto SS, Gerald WL, Sawyers CL.

Nat Genet. 2009 May;41(5):524-6. doi: 10.1038/ng.371. Epub 2009 Apr 26.

21.

Bead-based profiling of tyrosine kinase phosphorylation identifies SRC as a potential target for glioblastoma therapy.

Du J, Bernasconi P, Clauser KR, Mani DR, Finn SP, Beroukhim R, Burns M, Julian B, Peng XP, Hieronymus H, Maglathlin RL, Lewis TA, Liau LM, Nghiemphu P, Mellinghoff IK, Louis DN, Loda M, Carr SA, Kung AL, Golub TR.

Nat Biotechnol. 2009 Jan;27(1):77-83. doi: 10.1038/nbt.1513. Epub 2008 Dec 21.

22.

Gene expression signature-based chemical genomic prediction identifies a novel class of HSP90 pathway modulators.

Hieronymus H, Lamb J, Ross KN, Peng XP, Clement C, Rodina A, Nieto M, Du J, Stegmaier K, Raj SM, Maloney KN, Clardy J, Hahn WC, Chiosis G, Golub TR.

Cancer Cell. 2006 Oct;10(4):321-30. Epub 2006 Sep 28.

23.

The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease.

Lamb J, Crawford ED, Peck D, Modell JW, Blat IC, Wrobel MJ, Lerner J, Brunet JP, Subramanian A, Ross KN, Reich M, Hieronymus H, Wei G, Armstrong SA, Haggarty SJ, Clemons PA, Wei R, Carr SA, Lander ES, Golub TR.

Science. 2006 Sep 29;313(5795):1929-35.

24.

A systems view of mRNP biology.

Hieronymus H, Silver PA.

Genes Dev. 2004 Dec 1;18(23):2845-60. Review.

25.

Genome-wide mRNA surveillance is coupled to mRNA export.

Hieronymus H, Yu MC, Silver PA.

Genes Dev. 2004 Nov 1;18(21):2652-62. Epub 2004 Oct 15.

26.

Genome-wide localization of the nuclear transport machinery couples transcriptional status and nuclear organization.

Casolari JM, Brown CR, Komili S, West J, Hieronymus H, Silver PA.

Cell. 2004 May 14;117(4):427-39.

27.

Genome-wide analysis of RNA-protein interactions illustrates specificity of the mRNA export machinery.

Hieronymus H, Silver PA.

Nat Genet. 2003 Feb;33(2):155-61. Epub 2003 Jan 13.

PMID:
12524544
28.

Field-ionization Stark spectra of Ba Rydberg atoms at high density of states.

König A, Neukammer J, Hieronymus H, Rinneberg H.

Phys Rev A. 1991 Mar 1;43(5):2402-2415. No abstract available.

PMID:
9905289
29.

Perturbed angular distribution of electrons following photoionization of 6sns 1S0 barium Rydberg states.

Hieronymus H, Kohl M, Neukammer J, König A, Rinneberg H, Spinger-Bolk H.

Phys Rev A. 1990 Feb 1;41(3):1477-1491. No abstract available.

PMID:
9903244
30.

Energies of high-n barium Rydberg states.

Neukammer J, Jönsson G, König A, Vietzke K, Hieronymus H, Rinneberg H.

Phys Rev A Gen Phys. 1988 Sep 15;38(6):2804-2814. No abstract available.

PMID:
9900697
31.

Transition from magnetic to electric-field (F||B) dominated spectra of barium at threshold.

König A, Neukammer J, Vietzke K, Kohl M, Grabka H, Hieronymus H, Rinneberg H.

Phys Rev A Gen Phys. 1988 Jul 1;38(1):547-550. No abstract available.

PMID:
9900207
32.

Spectroscopy of Rydberg atoms at n

Neukammer J, Rinneberg H, Vietzke K, König A, Hieronymus H, Kohl M, Grabka H, Wunner G.

Phys Rev Lett. 1987 Dec 28;59(26):2947-2950. No abstract available.

PMID:
10035694
33.

Autoionization inhibited by internal interferences.

Neukammer J, Rinneberg H, Jönsson G, Cooke WE, Hieronymus H, König A, Vietzke K, Springer-Bolk H.

Phys Rev Lett. 1985 Nov 4;55(19):1979-1982. No abstract available.

PMID:
10031978
34.

High n Rydberg atoms and external fields.

Rinneberg H, Neukammer J, Jönsson G, Hieronymus H, König A, Vietzke K.

Phys Rev Lett. 1985 Jul 22;55(4):382-385. No abstract available.

PMID:
10032336
35.

[The federal social welfare law].

HIERONYMUS HE.

Offentl Gesundheitsdienst. 1961 Oct;23:486-97. German. No abstract available.

PMID:
13907211

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