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Items: 1 to 50 of 349

1.

Dynamic differences in dietary polyunsaturated fatty acid metabolism in sputum of COPD patients and controls.

van der Does AM, Heijink M, Mayboroda OA, Persson LJ, Aanerud M, Bakke P, Eagan TM, Hiemstra PS, Giera M.

Biochim Biophys Acta Mol Cell Biol Lipids. 2018 Dec 5;1864(3):224-233. doi: 10.1016/j.bbalip.2018.11.012. [Epub ahead of print]

2.

How to write a response to the reviewers of your manuscript.

Hiemstra PS.

Breathe (Sheff). 2018 Dec;14(4):319-321. doi: 10.1183/20734735.025818.

3.

Electronic Cigarettes - Task Force report from the European Respiratory Society.

Bals R, Boyd J, Esposito S, Foronjy R, Hiemstra PS, Jiménez-Ruiz CA, Katsaounou P, Lindberg A, Metz C, Schober W, Spira A, Blasi F.

Eur Respir J. 2018 Nov 21. pii: 1801151. doi: 10.1183/13993003.01151-2018. [Epub ahead of print]

PMID:
30464018
4.

An airway epithelial IL-17A response signature identifies a steroid-unresponsive COPD patient subgroup.

Christenson SA, van den Berge M, Faiz A, Inkamp K, Bhakta N, Bonser LR, Zlock LT, Barjaktarevic IZ, Barr RG, Bleecker ER, Boucher RC, Bowler RP, Comellas AP, Curtis JL, Han MK, Hansel NN, Hiemstra PS, Kaner RJ, Krishnanm JA, Martinez FJ, O'Neal WK, Paine R 3rd, Timens W, Wells JM, Spira A, Erle DJ, Woodruff PG.

J Clin Invest. 2019 Jan 2;129(1):169-181. doi: 10.1172/JCI121087. Epub 2018 Nov 26.

5.

Retinoic acid signaling balances adult distal lung epithelial progenitor cell growth and differentiation.

Ng-Blichfeldt JP, Schrik A, Kortekaas RK, Noordhoek JA, Heijink IH, Hiemstra PS, Stolk J, Königshoff M, Gosens R.

EBioMedicine. 2018 Oct;36:461-474. doi: 10.1016/j.ebiom.2018.09.002. Epub 2018 Sep 17.

6.

microRNA-mRNA regulatory networks underlying chronic mucus hypersecretion in COPD.

Tasena H, Faiz A, Timens W, Noordhoek J, Hylkema MN, Gosens R, Hiemstra PS, Spira A, Postma DS, Tew GW, Grimbaldeston MA, van den Berge M, Heijink IH, Brandsma CA.

Eur Respir J. 2018 Sep 6;52(3). pii: 1701556. doi: 10.1183/13993003.01556-2017. Print 2018 Sep.

PMID:
30072506
7.

Contribution of Host Defence Proteins and Peptides to Host-Microbiota Interactions in Chronic Inflammatory Lung Diseases.

van der Does AM, Amatngalim GD, Keijser B, Hiemstra PS, Villenave R.

Vaccines (Basel). 2018 Jul 28;6(3). pii: E49. doi: 10.3390/vaccines6030049. Review.

8.

Stem cell-based Lung-on-Chips: The best of both worlds?

Nawroth JC, Barrile R, Conegliano D, van Riet S, Hiemstra PS, Villenave R.

Adv Drug Deliv Rev. 2018 Jul 25. pii: S0169-409X(18)30169-8. doi: 10.1016/j.addr.2018.07.005. [Epub ahead of print] Review.

PMID:
30009883
9.

Immune responses in the treatment of drug-sensitive pulmonary tuberculosis with phenylbutyrate and vitamin D3 as host directed therapy.

Rekha RS, Mily A, Sultana T, Haq A, Ahmed S, Mostafa Kamal SM, van Schadewijk A, Hiemstra PS, Gudmundsson GH, Agerberth B, Raqib R.

BMC Infect Dis. 2018 Jul 4;18(1):303. doi: 10.1186/s12879-018-3203-9.

10.

Serum periostin does not reflect type 2-driven inflammation in COPD.

Carpaij OA, Muntinghe FOW, Wagenaar MB, Habing JW, Timens W, Kerstjens HAM, Nawijn MC, Kunz LIZ, Hiemstra PS, Tew GW, Holweg CTJ, Brandsma CA, van den Berge M.

Respir Res. 2018 Jun 7;19(1):112. doi: 10.1186/s12931-018-0818-8.

11.

Immunomodulatory innate defence regulator (IDR) peptide alleviates airway inflammation and hyper-responsiveness.

Piyadasa H, Hemshekhar M, Altieri A, Basu S, van der Does AM, Halayko AJ, Hiemstra PS, Mookherjee N.

Thorax. 2018 Oct;73(10):908-917. doi: 10.1136/thoraxjnl-2017-210739. Epub 2018 May 31.

PMID:
29853649
12.

Aerobic Exercise Protects from Pseudomonas aeruginosa-Induced Pneumonia in Elderly Mice.

Stravinskas Durigon T, MacKenzie B, Carneiro Oliveira-Junior M, Santos-Dias A, De Angelis K, Malfitano C, Kelly da Palma R, Moreno Guerra J, Damaceno-Rodrigues NR, Garcia Caldini E, de Almeida FM, Aquino-Santos HC, Rigonato-Oliveira NC, Leal de Oliveira DB, Aimbire F, Ligeiro de Oliveira AP, Franco de Oliveira LV, Durigon EL, Hiemstra PS, Vieira RP.

J Innate Immun. 2018;10(4):279-290. doi: 10.1159/000488953. Epub 2018 May 29.

13.

A novel method for expansion and differentiation of mouse tracheal epithelial cells in culture.

Eenjes E, Mertens TCJ, Buscop-van Kempen MJ, van Wijck Y, Taube C, Rottier RJ, Hiemstra PS.

Sci Rep. 2018 May 9;8(1):7349. doi: 10.1038/s41598-018-25799-6.

14.

Basic and translational research in the European Respiratory Journal.

Farré R, Hiemstra PS, Dinh-Xuan AT.

Eur Respir J. 2018 May 3;51(5). pii: 1800377. doi: 10.1183/13993003.00377-2018. Print 2018 May. No abstract available.

PMID:
29724787
15.

Predictive value of eosinophils and neutrophils on clinical effects of ICS in COPD.

Hartjes FJ, Vonk JM, Faiz A, Hiemstra PS, Lapperre TS, Kerstjens HAM, Postma DS, van den Berge M; and the Groningen and Leiden Universities Corticosteroids in Obstructive Lung Disease (GLUCOLD) Study Group.

Respirology. 2018 Nov;23(11):1023-1031. doi: 10.1111/resp.13312. Epub 2018 Apr 26.

16.

Airway Epithelial Cell Function and Respiratory Host Defense in Chronic Obstructive Pulmonary Disease.

Amatngalim GD, Hiemstra PS.

Chin Med J (Engl). 2018 May 5;131(9):1099-1107. doi: 10.4103/0366-6999.230743. No abstract available.

17.

Response to Comment on "Therapeutic Application of an Extract of Helicobacter pylori Ameliorates the Development of Allergic Airway Disease".

van Wijck Y, Hiemstra PS, Taube C.

J Immunol. 2018 May 1;200(9):3027-3028. doi: 10.4049/jimmunol.1800260. No abstract available.

PMID:
29685947
18.

Mesenchymal stromal cells: a novel therapy for the treatment of chronic obstructive pulmonary disease?

Broekman W, Khedoe PPSJ, Schepers K, Roelofs H, Stolk J, Hiemstra PS.

Thorax. 2018 Jun;73(6):565-574. doi: 10.1136/thoraxjnl-2017-210672. Epub 2018 Apr 13. Review.

19.

Aberrant epithelial differentiation by cigarette smoke dysregulates respiratory host defence.

Amatngalim GD, Schrumpf JA, Dishchekenian F, Mertens TCJ, Ninaber DK, van der Linden AC, Pilette C, Taube C, Hiemstra PS, van der Does AM.

Eur Respir J. 2018 Apr 26;51(4). pii: 1701009. doi: 10.1183/13993003.01009-2017. Print 2018 Apr.

PMID:
29545277
20.

Effects of E-Cigarette Use on Human Lung Tissue. On Harm Reduction and Causing Harm.

Hiemstra PS, Bals R.

Am J Respir Crit Care Med. 2018 Jul 1;198(1):6-7. doi: 10.1164/rccm.201802-0299ED. No abstract available.

PMID:
29518342
21.

Assembly 3: Basic and Translational Sciences.

Greene CM, Hiemstra PS.

Breathe (Sheff). 2018 Mar;14(1):67-68. doi: 10.1183/20734735.020017.

22.

Farm dust reduces viral load in human bronchial epithelial cells by increasing barrier function and antiviral responses.

van der Vlugt LEPM, Eger K, Müller C, Ninaber DK, Zarcone MC, Amatngalim GD, Bracher F, von Mutius E, Smits HH, Hiemstra PS.

J Allergy Clin Immunol. 2018 May;141(5):1949-1952.e8. doi: 10.1016/j.jaci.2018.01.025. Epub 2018 Feb 7. No abstract available.

PMID:
29425849
23.

Effect of diesel exhaust generated by a city bus engine on stress responses and innate immunity in primary bronchial epithelial cell cultures.

Zarcone MC, Duistermaat E, Alblas MJ, van Schadewijk A, Ninaber DK, Clarijs V, Moerman MM, Vaessen D, Hiemstra PS, Kooter IM.

Toxicol In Vitro. 2018 Apr;48:221-231. doi: 10.1016/j.tiv.2018.01.024.

24.

Therapeutic Application of an Extract of Helicobacter pylori Ameliorates the Development of Allergic Airway Disease.

van Wijck Y, de Kleijn S, John-Schuster G, Mertens TCJ, Hiemstra PS, Müller A, Smits HH, Taube C.

J Immunol. 2018 Mar 1;200(5):1570-1579. doi: 10.4049/jimmunol.1700987. Epub 2018 Jan 19.

PMID:
29352004
25.

Associations of Serum 25(OH)D Concentrations with Lung Function, Airway Inflammation and Common Cold in the General Population.

Rafiq R, Thijs W, Prein R, de Jongh RT, Taube C, Hiemstra PS, de Mutsert R, den Heijer M.

Nutrients. 2018 Jan 3;10(1). pii: E35. doi: 10.3390/nu10010035.

26.

Pulmonary function, exhaled nitric oxide and symptoms in asthma patients with obesity: a cross-sectional study.

Kasteleyn MJ, Bonten TN, de Mutsert R, Thijs W, Hiemstra PS, le Cessie S, Rosendaal FR, Chavannes NH, Taube C.

Respir Res. 2017 Dec 7;18(1):205. doi: 10.1186/s12931-017-0684-9.

27.

Reprogramming of cellular metabolism: driver for airway remodelling in COPD?

Hiemstra PS, van der Does AM.

Eur Respir J. 2017 Nov 30;50(5). pii: 1702197. doi: 10.1183/13993003.02197-2017. Print 2017 Nov. No abstract available.

PMID:
29191957
28.

Human lung epithelial cell cultures for analysis of inhaled toxicants: Lessons learned and future directions.

Hiemstra PS, Grootaers G, van der Does AM, Krul CAM, Kooter IM.

Toxicol In Vitro. 2018 Mar;47:137-146. doi: 10.1016/j.tiv.2017.11.005. Epub 2017 Nov 15. Review.

29.

High intensity training in obesity: a Meta-analysis.

Türk Y, Theel W, Kasteleyn MJ, Franssen FME, Hiemstra PS, Rudolphus A, Taube C, Braunstahl GJ.

Obes Sci Pract. 2017 May 29;3(3):258-271. doi: 10.1002/osp4.109. eCollection 2017 Sep. Review.

30.

microRNA profiling in lung tissue and bronchoalveolar lavage of cigarette smoke-exposed mice and in COPD patients: a translational approach.

Conickx G, Avila Cobos F, van den Berge M, Faiz A, Timens W, Hiemstra PS, Joos GF, Brusselle GG, Mestdagh P, Bracke KR.

Sci Rep. 2017 Oct 9;7(1):12871. doi: 10.1038/s41598-017-13265-8.

31.

Airway Epithelial Barrier Dysfunction in Chronic Obstructive Pulmonary Disease: Role of Cigarette Smoke Exposure.

Aghapour M, Raee P, Moghaddam SJ, Hiemstra PS, Heijink IH.

Am J Respir Cell Mol Biol. 2018 Feb;58(2):157-169. doi: 10.1165/rcmb.2017-0200TR. Review.

PMID:
28933915
32.

Acute and chronic effects of treatment with mesenchymal stromal cells on LPS-induced pulmonary inflammation, emphysema and atherosclerosis development.

Khedoe PPSJ, de Kleijn S, van Oeveren-Rietdijk AM, Plomp JJ, de Boer HC, van Pel M, Rensen PCN, Berbée JFP, Hiemstra PS.

PLoS One. 2017 Sep 14;12(9):e0183741. doi: 10.1371/journal.pone.0183741. eCollection 2017.

33.

Pre-surgical Pulmonary Rehabilitation in Asthma Patients Undergoing Bariatric Surgery.

Türk Y, van Huisstede A, Hiemstra PS, Taube C, Braunstahl GJ.

Obes Surg. 2017 Nov;27(11):3055-3060. doi: 10.1007/s11695-017-2888-y.

PMID:
28831733
34.

The Effects of Selective Hematopoietic Expression of Human IL-37 on Systemic Inflammation and Atherosclerosis in LDLr-Deficient Mice.

Hoeke G, Khedoe PPSJ, van Diepen JA, Pike-Overzet K, van de Ven B, Vazirpanah N, Mol I, Hiemstra PS, Staal FJT, Stienstra R, Netea MG, Dinarello CA, Rensen PCN, Berbée JFP.

Int J Mol Sci. 2017 Aug 9;18(8). pii: E1672. doi: 10.3390/ijms18081672.

35.

Bone Morphogenetic Protein 9 Protects against Neonatal Hyperoxia-Induced Impairment of Alveolarization and Pulmonary Inflammation.

Chen X, Orriols M, Walther FJ, Laghmani EH, Hoogeboom AM, Hogen-Esch ACB, Hiemstra PS, Folkerts G, Goumans MTH, Ten Dijke P, Morrell NW, Wagenaar GTM.

Front Physiol. 2017 Jul 13;8:486. doi: 10.3389/fphys.2017.00486. eCollection 2017.

36.

Cigarette smoke differentially affects IL-13-induced gene expression in human airway epithelial cells.

Mertens TCJ, van der Does AM, Kistemaker LE, Ninaber DK, Taube C, Hiemstra PS.

Physiol Rep. 2017 Jul;5(13). pii: e13347. doi: 10.14814/phy2.13347. Epub 2017 Jul 11.

37.

The effect of tiotropium in combination with olodaterol on house dust mite-induced allergic airway disease.

John-Schuster G, de Kleijn S, van Wijck Y, Kremer V, Smits HH, Pieper MP, Hiemstra PS, Taube C.

Pulm Pharmacol Ther. 2017 Aug;45:210-217. doi: 10.1016/j.pupt.2017.06.010. Epub 2017 Jul 5.

38.

Airway inflammation in COPD after long-term withdrawal of inhaled corticosteroids.

Kunz LIZ, Ten Hacken NH, Lapperre TS, Timens W, Kerstjens HAM, van Schadewijk A, Vonk JM, Sont JK, Snoeck-Stroband JB, Postma DS, Sterk PJ, Hiemstra PS; GLUCOLD Study Group.

Eur Respir J. 2017 Jun 15;49(6). pii: 1700848. doi: 10.1183/13993003.00848-2017. Print 2017 Jun. No abstract available.

39.

Use of airway epithelial cell culture to unravel the pathogenesis and study treatment in obstructive airway diseases.

Mertens TCJ, Karmouty-Quintana H, Taube C, Hiemstra PS.

Pulm Pharmacol Ther. 2017 Aug;45:101-113. doi: 10.1016/j.pupt.2017.05.008. Epub 2017 May 11. Review.

PMID:
28502841
40.

Defining asthma-COPD overlap syndrome: a population-based study.

Bonten TN, Kasteleyn MJ, de Mutsert R, Hiemstra PS, Rosendaal FR, Chavannes NH, Slats AM, Taube C.

Eur Respir J. 2017 May 1;49(5). pii: 1602008. doi: 10.1183/13993003.02008-2016. Print 2017 May.

41.

Aberrant DNA methylation and expression of SPDEF and FOXA2 in airway epithelium of patients with COPD.

Song J, Heijink IH, Kistemaker LEM, Reinders-Luinge M, Kooistra W, Noordhoek JA, Gosens R, Brandsma CA, Timens W, Hiemstra PS, Rots MG, Hylkema MN.

Clin Epigenetics. 2017 Apr 24;9:42. doi: 10.1186/s13148-017-0341-7. eCollection 2017.

42.

Effect of an Outpatient Pulmonary Rehabilitation Program on Exercise Tolerance and Asthma Control in Obese Asthma Patients.

Türk Y, van Huisstede A, Franssen FME, Hiemstra PS, Rudolphus A, Taube C, Braunstahl GJ.

J Cardiopulm Rehabil Prev. 2017 May;37(3):214-222. doi: 10.1097/HCR.0000000000000249.

PMID:
28448379
43.

Antimicrobial peptide levels are linked to airway inflammation, bacterial colonisation and exacerbations in chronic obstructive pulmonary disease.

Persson LJ, Aanerud M, Hardie JA, Miodini Nilsen R, Bakke PS, Eagan TM, Hiemstra PS.

Eur Respir J. 2017 Mar 15;49(3). pii: 1601328. doi: 10.1183/13993003.01328-2016. Print 2017 Mar.

44.

Proinflammatory Cytokines Impair Vitamin D-Induced Host Defense in Cultured Airway Epithelial Cells.

Schrumpf JA, Amatngalim GD, Veldkamp JB, Verhoosel RM, Ninaber DK, Ordonez SR, van der Does AM, Haagsman HP, Hiemstra PS.

Am J Respir Cell Mol Biol. 2017 Jun;56(6):749-761. doi: 10.1165/rcmb.2016-0289OC.

PMID:
28231019
45.

Antibacterial Defense of Human Airway Epithelial Cells from Chronic Obstructive Pulmonary Disease Patients Induced by Acute Exposure to Nontypeable Haemophilus influenzae: Modulation by Cigarette Smoke.

Amatngalim GD, Schrumpf JA, Henic A, Dronkers E, Verhoosel RM, Ordonez SR, Haagsman HP, Fuentes ME, Sridhar S, Aarbiou J, Janssen RAJ, Lekkerkerker AN, Hiemstra PS.

J Innate Immun. 2017;9(4):359-374. doi: 10.1159/000455193. Epub 2017 Feb 8.

46.

Diesel exhaust alters the response of cultured primary bronchial epithelial cells from patients with chronic obstructive pulmonary disease (COPD) to non-typeable Haemophilus influenzae.

Zarcone MC, van Schadewijk A, Duistermaat E, Hiemstra PS, Kooter IM.

Respir Res. 2017 Jan 28;18(1):27. doi: 10.1186/s12931-017-0510-4.

47.

Standard radiotherapy but not chemotherapy impairs systemic immunity in non-small cell lung cancer.

Talebian Yazdi M, Schinkelshoek MS, Loof NM, Taube C, Hiemstra PS, Welters MJ, van der Burg SH.

Oncoimmunology. 2016 Nov 8;5(12):e1255393. doi: 10.1080/2162402X.2016.1255393. eCollection 2016.

48.

Airway inflammation in COPD after long-term withdrawal of inhaled corticosteroids.

Kunz LI, Ten Hacken NH, Lapperre TS, Timens W, Kerstjens HA, van Schadewijk A, Vonk JM, Sont JK, Snoeck-Stroband JB, Postma DS, Sterk PJ, Hiemstra PS; GLUCOLD Study Group.

Eur Respir J. 2017 Jan 3;49(1). pii: 1600839. doi: 10.1183/13993003.00839-2016. Print 2017 Jan.

49.

Cigarette Smoke Modulates Repair and Innate Immunity following Injury to Airway Epithelial Cells.

Amatngalim GD, Broekman W, Daniel NM, van der Vlugt LE, van Schadewijk A, Taube C, Hiemstra PS.

PLoS One. 2016 Nov 9;11(11):e0166255. doi: 10.1371/journal.pone.0166255. eCollection 2016.

50.

Childhood allergies and asthma: New insights on environmental exposures and local immunity at the lung barrier.

Smits HH, van der Vlugt LE, von Mutius E, Hiemstra PS.

Curr Opin Immunol. 2016 Oct;42:41-47. doi: 10.1016/j.coi.2016.05.009. Epub 2016 May 30. Review.

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